3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Carcinoma, Renal Cell in 1 studies
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.
Carcinoma, Renal Cell: A heterogeneous group of sporadic or hereditary carcinoma derived from cells of the KIDNEYS. There are several subtypes including the clear cells, the papillary, the chromophobe, the collecting duct, the spindle cells (sarcomatoid), or mixed cell-type carcinoma.
| Excerpt | Relevance | Reference |
|---|---|---|
| "YC-1 displayed cytotoxicity in renal carcinoma cells at 10(-7)-10(-8) M." | 1.35 | YC-1 induces apoptosis of human renal carcinoma A498 cells in vitro and in vivo through activation of the JNK pathway. ( Chang, YL; Chen, TH; Guh, JH; Huang, DY; Kuo, SC; Lee, FY; Liao, CH; Pan, SL; Teng, CM; Wu, SY, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, SY | 1 |
| Pan, SL | 1 |
| Chen, TH | 1 |
| Liao, CH | 1 |
| Huang, DY | 1 |
| Guh, JH | 1 |
| Chang, YL | 1 |
| Kuo, SC | 1 |
| Lee, FY | 1 |
| Teng, CM | 1 |
1 other study available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Carcinoma, Renal Cell
| Article | Year |
|---|---|
YC-1 induces apoptosis of human renal carcinoma A498 cells in vitro and in vivo through activation of the JNK pathway.
Topics: Animals; Apoptosis; Carcinoma, Renal Cell; Caspase 3; Caspase 8; Chromatin; Dose-Response Relationsh | 2008 |