3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Carcinoma, Epidermoid in 5 studies
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Head and neck squamous cell carcinoma (HNSCC) is an aggressive and often fatal disease." | 1.46 | Soluble guanylate cyclase stimulators increase sensitivity to cisplatin in head and neck squamous cell carcinoma cells. ( Ben-Jonathan, N; Kumar, B; Kumar, P; Takiar, V; Tuttle, TR, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tuttle, TR | 1 |
| Takiar, V | 1 |
| Kumar, B | 1 |
| Kumar, P | 1 |
| Ben-Jonathan, N | 1 |
| Hirabayashi, T | 1 |
| Takahashi, H | 1 |
| Watanabe, M | 1 |
| Tachibana, T | 1 |
| Moon, SY | 1 |
| Chang, HW | 1 |
| Roh, JL | 1 |
| Kim, GC | 1 |
| Choi, SH | 1 |
| Lee, SW | 1 |
| Cho, KJ | 1 |
| Nam, SY | 1 |
| Kim, SY | 1 |
| Feng, Y | 2 |
| Zhu, H | 2 |
| Ling, T | 1 |
| Hao, B | 2 |
| Zhang, G | 2 |
| Shi, R | 2 |
| Zhang, J | 1 |
| Zhou, X | 1 |
5 other studies available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Carcinoma, Epidermoid
| Article | Year |
|---|---|
Soluble guanylate cyclase stimulators increase sensitivity to cisplatin in head and neck squamous cell carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; beta Catenin; Carcinoma, Squamous Cell | 2017 |
Establishment and characterization of a squamous cell carcinoma cell line, designated hZK-1, derived from a metastatic lymph node tumor of the tongue.
Topics: Aged, 80 and over; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell | 2017 |
Using YC-1 to overcome the radioresistance of hypoxic cancer cells.
Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Humans; Hypoxia-Inducible Factor 1, alpha | 2009 |
Effects of YC-1 targeting hypoxia-inducible factor 1 alpha in oesophageal squamous carcinoma cell line Eca109 cells.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell P | 2011 |
Inhibition of hypoxia inducible factor 1α expression suppresses the progression of esophageal squamous cell carcinoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; | 2011 |