3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Carcinoma, Anaplastic in 4 studies
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hep3B hepatoma, NCI-H87 stomach carcinoma, Caki-1 renal carcinoma, SiHa cervical carcinoma, and SK-N-MC neuroblastoma cells were grown as xenografts in immunodeficient mice (69 mice total)." | 1.32 | YC-1: a potential anticancer drug targeting hypoxia-inducible factor 1. ( Cho, YS; Chun, YS; Kim, J; Kim, MS; Lee, JC; Park, JW; Yeo, EJ, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wakiyama, K | 1 |
| Kitajima, Y | 1 |
| Tanaka, T | 1 |
| Kaneki, M | 1 |
| Yanagihara, K | 1 |
| Aishima, S | 1 |
| Nakamura, J | 1 |
| Noshiro, H | 1 |
| Hong, B | 1 |
| Lui, VW | 1 |
| Hui, EP | 1 |
| Lu, Y | 1 |
| Leung, HS | 1 |
| Wong, EY | 1 |
| Cheng, SH | 1 |
| Ng, MH | 1 |
| Mills, GB | 1 |
| Chan, AT | 1 |
| Lee, CS | 1 |
| Kwak, SW | 1 |
| Kim, YJ | 1 |
| Lee, SA | 1 |
| Park, ES | 1 |
| Myung, SC | 1 |
| Kim, W | 1 |
| Lee, MS | 1 |
| Lee, JJ | 1 |
| Yeo, EJ | 1 |
| Chun, YS | 1 |
| Cho, YS | 1 |
| Kim, J | 1 |
| Lee, JC | 1 |
| Kim, MS | 1 |
| Park, JW | 1 |
4 other studies available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Carcinoma, Anaplastic
| Article | Year |
|---|---|
Low-dose YC-1 combined with glucose and insulin selectively induces apoptosis in hypoxic gastric carcinoma cells by inhibiting anaerobic glycolysis.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetyl Coenzyme A; Anaerobiosis; Animals; Apoptosis; Carcinoma; Cell Li | 2017 |
Reverse phase protein array identifies novel anti-invasion mechanisms of YC-1.
Topics: Antineoplastic Agents; Carcinoma; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Checkpo | 2010 |
Guanylate cyclase activator YC-1 potentiates apoptotic effect of licochalcone A on human epithelial ovarian carcinoma cells via activation of death receptor and mitochondrial pathways.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma; Carcinoma, O | 2012 |
YC-1: a potential anticancer drug targeting hypoxia-inducible factor 1.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Carcinoma; Carcinoma, Hepatocellular; Cell | 2003 |