3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Cancer of Prostate in 3 studies
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In contrast, prostate cancer cells exposed to acute hypoxia (≤6 h) displayed increased motility, clonogenic survival, and invasive capacity." | 1.37 | Impact of hypoxia on the metastatic potential of human prostate cancer cells. ( Bae, K; Dai, Y; Siemann, DW, 2011) |
| "Hormone-refractory metastatic human prostate cancer PC-3 cells were selected for this study." | 1.33 | YC-1 suppresses constitutive nuclear factor-kappaB activation and induces apoptosis in human prostate cancer cells. ( Chang, YL; Guh, JH; Huang, YT; Kuo, SC; Lee, FY; Pan, SL; Teng, CM, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dai, Y | 1 |
| Bae, K | 1 |
| Siemann, DW | 1 |
| Huang, YT | 2 |
| Pan, SL | 2 |
| Guh, JH | 2 |
| Chang, YL | 1 |
| Lee, FY | 2 |
| Kuo, SC | 2 |
| Teng, CM | 2 |
| Sun, HL | 1 |
| Liu, YN | 1 |
| Huang, DY | 1 |
3 other studies available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Cancer of Prostate
| Article | Year |
|---|---|
Impact of hypoxia on the metastatic potential of human prostate cancer cells.
Topics: Cell Death; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Enzyme | 2011 |
YC-1 suppresses constitutive nuclear factor-kappaB activation and induces apoptosis in human prostate cancer cells.
Topics: Adenocarcinoma; Animals; Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; Cell Cycle; Cell Line, | 2005 |
YC-1 inhibits HIF-1 expression in prostate cancer cells: contribution of Akt/NF-kappaB signaling to HIF-1alpha accumulation during hypoxia.
Topics: Aryl Hydrocarbon Receptor Nuclear Translocator; Blotting, Western; Cell Hypoxia; Cell Line, Tumor; D | 2007 |