3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Cancer of Pancreas in 5 studies
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Human pancreatic cancer PC-3 cells were incubated under normoxic or hypoxic conditions." | 1.34 | Effects of YC-1 on hypoxia-inducible factor 1-driven transcription activity, cell proliferative vitality, and apoptosis in hypoxic human pancreatic cancer cells. ( Du, J; Gu, H; Liu, N; Qin, H; Teng, X; Zhang, Q; Zhao, Q, 2007) |
| "Human pancreatic cancer PC-3 cells were incubated under hypoxic culture conditions." | 1.33 | [Inhibitory effect of YC-1 on induction of VEGF and GPI genes in hypoxic human pancreatic cancer cells]. ( Du, J; Gu, H; Liu, NZ; Qin, H; Teng, XL; Zhao, Q, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, LH | 1 |
| Pan, SL | 1 |
| Lai, CY | 1 |
| Tsai, AC | 1 |
| Teng, CM | 1 |
| Cho, IR | 1 |
| Kaowinn, S | 1 |
| Moon, J | 1 |
| Soh, J | 1 |
| Kang, HY | 1 |
| Jung, CR | 1 |
| Oh, S | 1 |
| Song, H | 1 |
| Koh, SS | 1 |
| Chung, YH | 1 |
| Wang, L | 1 |
| Zhou, W | 1 |
| Gou, S | 1 |
| Wang, T | 1 |
| Liu, T | 1 |
| Wang, C | 1 |
| Du, J | 2 |
| Zhao, Q | 2 |
| Gu, H | 2 |
| Teng, XL | 1 |
| Qin, H | 2 |
| Liu, NZ | 1 |
| Teng, X | 1 |
| Zhang, Q | 1 |
| Liu, N | 1 |
5 other studies available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Cancer of Pancreas
| Article | Year |
|---|---|
Activated PAR-2 regulates pancreatic cancer progression through ILK/HIF-α-induced TGF-α expression and MEK/VEGF-A-mediated angiogenesis.
Topics: Basic Helix-Loop-Helix Transcription Factors; Cell Line, Tumor; Down-Regulation; Flavonoids; Humans; | 2013 |
Oncotropic H-1 parvovirus infection degrades HIF-1α protein in human pancreatic cancer cells independently of VHL and RACK1.
Topics: Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; GTP-Binding Proteins; H-1 parvovirus; Hu | 2015 |
Insulin promotes proliferative vitality and invasive capability of pancreatic cancer cells via hypoxia-inducible factor 1alpha pathway.
Topics: Cell Line, Tumor; Cell Proliferation; Guanylate Cyclase; Humans; Hypoxia-Inducible Factor 1, alpha S | 2010 |
[Inhibitory effect of YC-1 on induction of VEGF and GPI genes in hypoxic human pancreatic cancer cells].
Topics: Blotting, Western; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Enzyme Activators; Gene Expre | 2006 |
Effects of YC-1 on hypoxia-inducible factor 1-driven transcription activity, cell proliferative vitality, and apoptosis in hypoxic human pancreatic cancer cells.
Topics: Apoptosis; Cell Division; Cell Hypoxia; Cell Line, Tumor; Enzyme Activators; Gene Expression Regulat | 2007 |