3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Cancer of Ovary in 6 studies
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The molecular mechanisms of ovarian cancer cell invasion under hypoxia remain unclear." | 1.42 | Hypoxia promotes HO-8910PM ovarian cancer cell invasion via Snail-mediated MT1-MMP upregulation. ( Deng, LL; Lin, P; Liu, Y; Lu, C; Qin, Z; Sun, L, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, JC | 1 |
| Chou, LC | 1 |
| Lien, JC | 1 |
| Wu, JC | 1 |
| Huang, CH | 1 |
| Chung, CH | 1 |
| Lee, FY | 1 |
| Huang, LJ | 1 |
| Kuo, SC | 1 |
| Way, TD | 1 |
| Liu, T | 1 |
| Zhao, L | 1 |
| Chen, W | 1 |
| Li, Z | 1 |
| Hou, H | 1 |
| Ding, L | 1 |
| Li, X | 1 |
| Sun, L | 1 |
| Lin, P | 1 |
| Qin, Z | 1 |
| Liu, Y | 1 |
| Deng, LL | 1 |
| Lu, C | 1 |
| Lee, SJ | 1 |
| Kim, YJ | 3 |
| Lee, CS | 3 |
| Bae, J | 1 |
| Kim, W | 2 |
| Myung, SC | 2 |
| Kwak, SW | 1 |
| Lee, SA | 1 |
| Park, ES | 1 |
| Lee, MS | 1 |
| Lee, JJ | 1 |
6 other studies available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Cancer of Ovary
| Article | Year |
|---|---|
CLC604 preferentially inhibits the growth of HER2-overexpressing cancer cells and sensitizes these cells to the inhibitory effect of Taxol in vitro and in vivo.
Topics: Animals; Antibiotics, Antineoplastic; Antibodies, Monoclonal, Humanized; Apoptosis; Breast Neoplasms | 2013 |
Inactivation of von Hippel-Lindau increases ovarian cancer cell aggressiveness through the HIF1α/miR-210/VMP1 signaling pathway.
Topics: Female; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; I | 2014 |
Hypoxia promotes HO-8910PM ovarian cancer cell invasion via Snail-mediated MT1-MMP upregulation.
Topics: Animals; Cell Culture Techniques; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Chick Embryo; | 2015 |
Combined application of camptothecin and the guanylate cyclase activator YC-1: Impact on cell death and apoptosis-related proteins in ovarian carcinoma cell lines.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Line, Tumor; DNA Damage; Enzyme Act | 2009 |
Guanylate cyclase activator YC-1 enhances TRAIL-induced apoptosis in human epithelial ovarian carcinoma cells via activation of apoptosis-related proteins.
Topics: Apoptosis; Biomarkers, Tumor; Caspase 8; Cell Line, Tumor; Enzyme Activators; Female; Guanylate Cycl | 2011 |
Guanylate cyclase activator YC-1 potentiates apoptotic effect of licochalcone A on human epithelial ovarian carcinoma cells via activation of death receptor and mitochondrial pathways.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma; Carcinoma, O | 2012 |