3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Blood Pressure, High in 4 studies
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypertension was induced in four additional groups of WKY rats by 3 weeks of oral treatment with L-NAME." | 1.31 | Acute blood pressure effects of YC-1-induced activation of soluble guanylyl cyclase in normotensive and hypertensive rats. ( Friebe, A; Koesling, D; Kreutz, R; Paul, M; Rothermund, L, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mónica, FZ | 1 |
| Antunes, E | 1 |
| Ndisang, JF | 1 |
| Zhao, W | 1 |
| Wang, R | 1 |
| Linder, AE | 1 |
| Weber, DS | 1 |
| Whitesall, SE | 1 |
| D'Alecy, LG | 1 |
| Webb, RC | 1 |
| Rothermund, L | 1 |
| Friebe, A | 1 |
| Paul, M | 1 |
| Koesling, D | 1 |
| Kreutz, R | 1 |
1 review available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Blood Pressure, High
| Article | Year |
|---|---|
Stimulators and activators of soluble guanylate cyclase for urogenital disorders.
Topics: Aging; Animals; Benzoates; Diabetes Complications; Enzyme Activators; Humans; Hypertension; Indazole | 2018 |
3 other studies available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Blood Pressure, High
| Article | Year |
|---|---|
Selective regulation of blood pressure by heme oxygenase-1 in hypertension.
Topics: Animals; Blood Pressure; Culture Techniques; Cyclic GMP; Guanylate Cyclase; Heme Oxygenase (Decycliz | 2002 |
Altered vascular reactivity in mice made hypertensive by nitric oxide synthase inhibition.
Topics: Acetylcholine; Animals; Aorta; Blood Pressure; Dose-Response Relationship, Drug; Endothelium, Vascul | 2005 |
Acute blood pressure effects of YC-1-induced activation of soluble guanylyl cyclase in normotensive and hypertensive rats.
Topics: Animals; Blood Pressure; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Guanylate Cyclase; | 2000 |