3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Asthma in 2 studies
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, X | 1 |
| Liu, C | 1 |
| Wu, L | 1 |
| Zhu, S | 1 |
| Crotty Alexander, LE | 1 |
| Akong-Moore, K | 1 |
| Feldstein, S | 1 |
| Johansson, P | 1 |
| Nguyen, A | 1 |
| McEachern, EK | 1 |
| Nicatia, S | 1 |
| Cowburn, AS | 1 |
| Olson, J | 1 |
| Cho, JY | 1 |
| Isaacs, H | 1 |
| Johnson, RS | 1 |
| Broide, DH | 1 |
| Nizet, V | 1 |
2 other studies available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Asthma
| Article | Year |
|---|---|
Potent ameliorating effect of Hypoxia-inducible factor 1α (HIF-1α) antagonist YC-1 on combined allergic rhinitis and asthma syndrome (CARAS) in Rats.
Topics: Animals; Anti-Allergic Agents; Asthma; Gene Expression Regulation; Hypoxia-Inducible Factor 1, alpha | 2016 |
Myeloid cell HIF-1α regulates asthma airway resistance and eosinophil function.
Topics: Airway Resistance; Animals; Asthma; Basic Helix-Loop-Helix Transcription Factors; Bronchoalveolar La | 2013 |