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3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Aging

3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Aging in 5 studies

3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mónica, FZ1
Antunes, E1
Alique, M1
Bodega, G1
Giannarelli, C1
Carracedo, J1
Ramírez, R1
Komsuoglu Celikyurt, I1
Utkan, T1
Ozer, C1
Gacar, N1
Aricioglu, F1
Kimura, K1
Iwano, M1
Higgins, DF1
Yamaguchi, Y1
Nakatani, K1
Harada, K1
Kubo, A1
Akai, Y1
Rankin, EB1
Neilson, EG1
Haase, VH1
Saito, Y1
Moreno, L1
Gonzalez-Luis, G1
Cogolludo, A1
Lodi, F1
Lopez-Farre, A1
Tamargo, J1
Villamor, E1
Perez-Vizcaino, F1

Reviews

1 review available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Aging

ArticleYear
Stimulators and activators of soluble guanylate cyclase for urogenital disorders.
    Nature reviews. Urology, 2018, Volume: 15, Issue:1

    Topics: Aging; Animals; Benzoates; Diabetes Complications; Enzyme Activators; Humans; Hypertension; Indazole

2018

Other Studies

4 other studies available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Aging

ArticleYear
MicroRNA-126 regulates Hypoxia-Inducible Factor-1α which inhibited migration, proliferation, and angiogenesis in replicative endothelial senescence.
    Scientific reports, 2019, 05-14, Volume: 9, Issue:1

    Topics: Aging; Antagomirs; Cardiovascular Diseases; Cell Hypoxia; Cell Movement; Cell Proliferation; Cells,

2019
Effects of YC-1 on learning and memory functions of aged rats.
    Medical science monitor basic research, 2014, Aug-21, Volume: 20

    Topics: Aging; Animals; Avoidance Learning; Indazoles; Male; Memory; Motor Activity; Rats, Wistar; Reaction

2014
Stable expression of HIF-1alpha in tubular epithelial cells promotes interstitial fibrosis.
    American journal of physiology. Renal physiology, 2008, Volume: 295, Issue:4

    Topics: Aging; Animals; Disease Models, Animal; Enzyme Activators; Epithelial Cells; Female; Fibrosis; Gene

2008
Soluble guanylyl cyclase during postnatal porcine pulmonary maturation.
    American journal of physiology. Lung cellular and molecular physiology, 2005, Volume: 288, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Base Sequence; Cyclic GMP; Enzyme Activators; Guanylate Cyclase; I

2005