3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Age-Related Osteoporosis in 1 studies
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Osteoporosis is a major health problem in postmenopausal women and the elderly that leads to fractures associated with substantial morbidity and mortality." | 1.48 | YC-1 alleviates bone loss in ovariectomized rats by inhibiting bone resorption and inducing extrinsic apoptosis in osteoclasts. ( Chen, TH; Chen, WY; Chien, JL; Chou, SJ; Chu, TH; Lu, KC; Shyu, JF; Wang, JW; Yeh, CB; Yen, MH, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, JW | 1 |
| Yeh, CB | 1 |
| Chou, SJ | 1 |
| Lu, KC | 1 |
| Chu, TH | 1 |
| Chen, WY | 1 |
| Chien, JL | 1 |
| Yen, MH | 1 |
| Chen, TH | 1 |
| Shyu, JF | 1 |
1 other study available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Age-Related Osteoporosis
| Article | Year |
|---|---|
YC-1 alleviates bone loss in ovariectomized rats by inhibiting bone resorption and inducing extrinsic apoptosis in osteoclasts.
Topics: Actins; Animals; Apoptosis; Bone Density Conservation Agents; Bone Resorption; Calpain; Cell Surviva | 2018 |