3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Adenocarcinoma Of Kidney in 1 studies
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "YC-1 displayed cytotoxicity in renal carcinoma cells at 10(-7)-10(-8) M." | 1.35 | YC-1 induces apoptosis of human renal carcinoma A498 cells in vitro and in vivo through activation of the JNK pathway. ( Chang, YL; Chen, TH; Guh, JH; Huang, DY; Kuo, SC; Lee, FY; Liao, CH; Pan, SL; Teng, CM; Wu, SY, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, SY | 1 |
| Pan, SL | 1 |
| Chen, TH | 1 |
| Liao, CH | 1 |
| Huang, DY | 1 |
| Guh, JH | 1 |
| Chang, YL | 1 |
| Kuo, SC | 1 |
| Lee, FY | 1 |
| Teng, CM | 1 |
1 other study available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Adenocarcinoma Of Kidney
| Article | Year |
|---|---|
YC-1 induces apoptosis of human renal carcinoma A498 cells in vitro and in vivo through activation of the JNK pathway.
Topics: Animals; Apoptosis; Carcinoma, Renal Cell; Caspase 3; Caspase 8; Chromatin; Dose-Response Relationsh | 2008 |