3-(4-octadecyl)benzoylacrylic-acid and Prostatic-Neoplasms--Castration-Resistant

3-(4-octadecyl)benzoylacrylic-acid has been researched along with Prostatic-Neoplasms--Castration-Resistant* in 1 studies

Other Studies

1 other study(ies) available for 3-(4-octadecyl)benzoylacrylic-acid and Prostatic-Neoplasms--Castration-Resistant

ArticleYear
Discovery and Structure-Based Optimization of Novel Atg4B Inhibitors for the Treatment of Castration-Resistant Prostate Cancer.
    Journal of medicinal chemistry, 2022, 03-24, Volume: 65, Issue:6

    Autophagy inhibition is an attractive target for cancer therapy. In this study, we discovered inhibitors of Atg4B essential for autophagosome formation and evaluated their potential as therapeutics for prostate cancer. Seventeen compounds were identified as candidates after

    Topics: Apoptosis; Autophagy; Autophagy-Related Proteins; Cell Line, Tumor; Cysteine Endopeptidases; Humans; Male; Prostatic Neoplasms, Castration-Resistant

2022