Compounds > 3-(3-pyridyl)-1-propyl-(2s)-1-(3-3-dimethyl-1-2-dioxopentyl)-2-pyrrolidinecarboxylate

3-(3-pyridyl)-1-propyl-(2s)-1-(3-3-dimethyl-1-2-dioxopentyl)-2-pyrrolidinecarboxylate and Parkinsonian-Disorders

3-(3-pyridyl)-1-propyl-(2s)-1-(3-3-dimethyl-1-2-dioxopentyl)-2-pyrrolidinecarboxylate has been researched along with Parkinsonian-Disorders* in 1 studies

Other Studies

1 other study(ies) available for 3-(3-pyridyl)-1-propyl-(2s)-1-(3-3-dimethyl-1-2-dioxopentyl)-2-pyrrolidinecarboxylate and Parkinsonian-Disorders

Article	Year
Solid-phase synthesis of FKBP12 inhibitors: N-sulfonyl and N-carbamoylprolyl/pipecolyl amides. Bioorganic & medicinal chemistry letters, 2002, May-20, Volume: 12, Issue:10 In parallel with our work on solution-phase parallel synthesis of ligands for the rotamase enzyme FKBP12, we herein report a methodology for the solid-phase synthesis of two classes of inhibitor, N-sulfonyl and N-carbamoylprolyl and pipecolyl amides along with their in vitro/in vivo biological results. Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Carbamates; Combinatorial Chemistry Techniques; Drug Design; Enzyme Inhibitors; Mice; Models, Molecular; Molecular Structure; Parkinsonian Disorders; Pipecolic Acids; Structure-Activity Relationship; Sulfonic Acids; Tacrolimus Binding Proteins	2002

Article

Year

Solid-phase synthesis of FKBP12 inhibitors: N-sulfonyl and N-carbamoylprolyl/pipecolyl amides.

Bioorganic & medicinal chemistry letters, 2002, May-20, Volume: 12, Issue:10

In parallel with our work on solution-phase parallel synthesis of ligands for the rotamase enzyme FKBP12, we herein report a methodology for the solid-phase synthesis of two classes of inhibitor, N-sulfonyl and N-carbamoylprolyl and pipecolyl amides along with their in vitro/in vivo biological results.

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Carbamates; Combinatorial Chemistry Techniques; Drug Design; Enzyme Inhibitors; Mice; Models, Molecular; Molecular Structure; Parkinsonian Disorders; Pipecolic Acids; Structure-Activity Relationship; Sulfonic Acids; Tacrolimus Binding Proteins

2002