3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5h)-furanone and Disease Models, Animal

3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5h)-furanone has been researched along with Disease Models, Animal in 7 studies

Research

Studies (7)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (28.57)	18.2507
2000's	4 (57.14)	29.6817
2010's	1 (14.29)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chen, W; Correa, L; Cramer, M; Lorrain, D; Munoz, B; Payne, J; Prasit, P; Reger, TS; Smith, ND; Stock, N; Yang, J; Zunic, J	1
Cebrián, C; Escartín, A; Esquivias, P; Esteva, F; García-González, MA; Lanas, A; Morandeira, A; Ortego, J; Piazuelo, E; Santander, S	1
Arnesen, H; Falk, E; Kontny, F; Kwong, E; Lyngdorf, L; Meztli, A; Olesen, M; Seljeflot, I	1
Arber, N; Birkenfeld, S; Bulvik, B; Dvory-Sobol, H; Kazanov, D; Leshno, M; Liberman, E; Luk, P	1
Dinchuk, JE; Evans, JF; Hancock, B; Kargman, SL; Kwong, E; Oshima, H; Oshima, M; Taketo, MM; Trzaskos, JM	1
Taketo, MM	1
Anderson, MA; Burgart, LJ; Buttar, NS; Krishnadath, KK; Leontovich, O; Lutzke, LS; Pacifico, RJ; Wang, KK; Westcott, JY	1

Reviews

1 review(s) available for 3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5h)-furanone and Disease Models, Animal

Article	Year
[Intestinal polyposis in APC knockout mice: mechanism of tumorigenesis and chemotherapy]. Seikagaku. The Journal of Japanese Biochemical Society, 1999, Volume: 71, Issue:11 Topics: Adenomatous Polyposis Coli; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; DNA-Binding Proteins; Furans; Heterozygote; Isoenzymes; Loss of Heterozygosity; Mice; Mice, Knockout; Prostaglandin-Endoperoxide Synthases; Signal Transduction; Trans-Activators; Transforming Growth Factor beta	1999

Article

Year

[Intestinal polyposis in APC knockout mice: mechanism of tumorigenesis and chemotherapy].

Seikagaku. The Journal of Japanese Biochemical Society, 1999, Volume: 71, Issue:11

Topics: Adenomatous Polyposis Coli; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; DNA-Binding Proteins; Furans; Heterozygote; Isoenzymes; Loss of Heterozygosity; Mice; Mice, Knockout; Prostaglandin-Endoperoxide Synthases; Signal Transduction; Trans-Activators; Transforming Growth Factor beta

1999

Other Studies

6 other study(ies) available for 3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5h)-furanone and Disease Models, Animal

Article	Year
Water soluble prodrug of a COX-2 selective inhibitor suitable for intravenous administration in models of cerebral ischemia. Bioorganic & medicinal chemistry letters, 2005, Jul-01, Volume: 15, Issue:13 Topics: Animals; Blood; Brain; Brain Ischemia; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Infusions, Intravenous; Inhibitory Concentration 50; Prodrugs; Prostaglandin-Endoperoxide Synthases; Rats; Solubility; Tissue Distribution	2005
Indomethacin but not a selective cyclooxygenase-2 inhibitor inhibits esophageal adenocarcinogenesis in rats. World journal of gastroenterology, 2012, Sep-21, Volume: 18, Issue:35 Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Barrett Esophagus; Cell Transformation, Neoplastic; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Disease Progression; Esophageal Neoplasms; Esophagitis; Esophagus; Female; Furans; Gastroesophageal Reflux; Indomethacin; Membrane Proteins; Metaplasia; Mucous Membrane; Rats; Rats, Wistar; Time Factors	2012
No effect of cyclooxygenase inhibition on plaque size in atherosclerosis-prone mice. Scandinavian cardiovascular journal : SCJ, 2002, Volume: 36, Issue:6 Topics: Algorithms; Analysis of Variance; Animals; Aorta, Thoracic; Aortic Diseases; Apolipoproteins E; Arteriosclerosis; Cyclooxygenase Inhibitors; Disease Models, Animal; Furans; Male; Mice; Mice, Inbred C57BL; Sulindac	2002
MF tricyclic and sulindac retard tumor formation in an animal model. International journal of cancer, 2006, Jan-01, Volume: 118, Issue:1 Topics: Administration, Oral; Animals; Antineoplastic Agents; Chemoprevention; Colorectal Neoplasms; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Furans; Injections, Subcutaneous; Liver Neoplasms; Mice; Mice, Nude; Placebos; Random Allocation; Single-Blind Method; Sulindac	2006
Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell, 1996, Nov-29, Volume: 87, Issue:5 Topics: Adenomatous Polyposis Coli; Adenomatous Polyposis Coli Protein; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytoskeletal Proteins; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Space; Female; Furans; Gene Dosage; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, APC; Intestinal Mucosa; Isoenzymes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutagenesis; Prostaglandin-Endoperoxide Synthases; Sulindac; Time Factors	1996
Chemoprevention of esophageal adenocarcinoma by COX-2 inhibitors in an animal model of Barrett's esophagus. Gastroenterology, 2002, Volume: 122, Issue:4 Topics: Adenocarcinoma; Animals; Barrett Esophagus; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Esophageal Neoplasms; Esophagitis; Furans; Gastroesophageal Reflux; Isoenzymes; Lactones; Male; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Sulfones	2002