3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid has been researched along with Status Epilepticus in 2 studies
3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid: structure given in first source; NMDA receptor antagonist
Status Epilepticus: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ifenprodil was maximally effective at 30 mg/kg." | 1.32 | A comparison of three NMDA receptor antagonists in the treatment of prolonged status epilepticus. ( Bertram, EH; Kapur, J; Williamson, J; Yen, W, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yen, W | 1 |
| Williamson, J | 1 |
| Bertram, EH | 2 |
| Kapur, J | 1 |
| Lothman, EW | 1 |
2 other studies available for 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid and Status Epilepticus
| Article | Year |
|---|---|
A comparison of three NMDA receptor antagonists in the treatment of prolonged status epilepticus.
Topics: Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Ami | 2004 |
NMDA receptor antagonists and limbic status epilepticus: a comparison with standard anticonvulsants.
Topics: Animals; Anticonvulsants; Dibenzocycloheptenes; Dizocilpine Maleate; Electric Stimulation; Hippocamp | 1990 |