3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid and Schizophrenia studies

3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid and Schizophrenia

3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid: structure given in first source; NMDA receptor antagonist

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research Excerpts

Excerpt	Relevance	Reference
"Haloperidol and clozapine were given intraperitoneally (IP) to animals that had received vehicle or a competitive NMDA receptor antagonist, 3-(R)-2-carboxypiperazin-4-propyl-1-phosphonic acid (CPP), directly into the medial prefrontal cortex."	1.35	Haloperidol and clozapine have dissociable effects in a model of attentional performance deficits induced by blockade of NMDA receptors in the mPFC. ( Baviera, M; Carli, M; Invernizzi, RW, 2008)

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (33.33)	18.2507
2000's	1 (33.33)	29.6817
2010's	1 (33.33)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

1 (33.33)

18.2507

2000's

1 (33.33)

29.6817

2010's

1 (33.33)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Carli, M	2
Calcagno, E	1
Mainolfi, P	1
Mainini, E	1
Invernizzi, RW	2
Baviera, M	1
Ujike, H	1
Tsuchida, H	1
Kanzaki, A	1
Akiyama, K	1
Otsuki, S	1

Studies

Carli, M

Calcagno, E

Mainolfi, P

Mainini, E

Invernizzi, RW

Baviera, M

Ujike, H

Tsuchida, H

Kanzaki, A

Akiyama, K

Otsuki, S

Other Studies

3 other studies available for 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid and Schizophrenia

Article	Year
Effects of aripiprazole, olanzapine, and haloperidol in a model of cognitive deficit of schizophrenia in rats: relationship with glutamate release in the medial prefrontal cortex. Psychopharmacology, 2011, Volume: 214, Issue:3 Topics: Analysis of Variance; Animals; Antipsychotic Agents; Aripiprazole; Behavior, Animal; Benzodiazepines	2011
Haloperidol and clozapine have dissociable effects in a model of attentional performance deficits induced by blockade of NMDA receptors in the mPFC. Psychopharmacology, 2008, Volume: 196, Issue:2 Topics: Analysis of Variance; Animals; Antipsychotic Agents; Attention; Behavior, Animal; Clozapine; Dopamin	2008
Competitive and non-competitive N-methyl-D-aspartate antagonists fail to prevent the induction of methamphetamine-induced sensitization. Life sciences, 1992, Volume: 50, Issue:22 Topics: Animals; Binding, Competitive; Dizocilpine Maleate; Drug Administration Schedule; Male; Methamphetam	1992

Article

Year

Effects of aripiprazole, olanzapine, and haloperidol in a model of cognitive deficit of schizophrenia in rats: relationship with glutamate release in the medial prefrontal cortex.

Psychopharmacology, 2011, Volume: 214, Issue:3

Topics: Analysis of Variance; Animals; Antipsychotic Agents; Aripiprazole; Behavior, Animal; Benzodiazepines

2011

Haloperidol and clozapine have dissociable effects in a model of attentional performance deficits induced by blockade of NMDA receptors in the mPFC.

Psychopharmacology, 2008, Volume: 196, Issue:2

Topics: Analysis of Variance; Animals; Antipsychotic Agents; Attention; Behavior, Animal; Clozapine; Dopamin

2008

Competitive and non-competitive N-methyl-D-aspartate antagonists fail to prevent the induction of methamphetamine-induced sensitization.

Life sciences, 1992, Volume: 50, Issue:22

Topics: Animals; Binding, Competitive; Dizocilpine Maleate; Drug Administration Schedule; Male; Methamphetam

1992