Compounds > 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid
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3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid and Nerve Degeneration

3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid has been researched along with Nerve Degeneration in 13 studies

3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid: structure given in first source; NMDA receptor antagonist

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's10 (76.92)18.2507
2000's2 (15.38)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ayala, GX1
Tapia, R1
Akaike, A1
Tamura, Y1
Yokota, T1
Shimohama, S1
Kimura, J1
Löschmann, PA2
Lange, KW2
Wachtel, H2
Turski, L3
Sofic, E1
Burg, M1
Horowski, R1
Kalveram, KT1
Riederer, P1
Jarrard, LE1
Meldrum, BS1
Bernert, H1
Pohl, D1
Bittigau, P1
Ishimaru, MJ1
Stadthaus, D1
Hübner, C1
Olney, JW1
Ikonomidou, C1
Pollack, AE1
Strauss, JB1
Vezzani, A1
Conti, M1
De Luigi, A1
Ravizza, T1
Moneta, D1
Marchesi, F1
De Simoni, MG1
Eriksson, C1
Zou, LP1
Ahlenius, S1
Winblad, B1
Schultzberg, M1
Bakker, MH1
Foster, AC2
Facci, L1
Leon, A1
Skaper, SD1
Gill, R1
Woodruff, GN1

Other Studies

13 other studies available for 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid and Nerve Degeneration

ArticleYear
Expression of heat shock protein 70 induced by 4-aminopyridine through glutamate-mediated excitotoxic stress in rat hippocampus in vivo.
    Neuropharmacology, 2003, Volume: 45, Issue:5

    Topics: 4-Aminopyridine; Animals; Anticonvulsants; Cell Count; Chromatography, High Pressure Liquid; Dizocil

2003
Nicotine-induced protection of cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity.
    Brain research, 1994, May-02, Volume: 644, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebral Cortex;

1994
MPTP-induced degeneration: interference with glutamatergic toxicity.
    Journal of neural transmission. Supplementum, 1994, Volume: 43

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Chromatography, High Pressure Liquid; Dopamin

1994
The competitive NMDA antagonist CPP protects substantia nigra neurons from MPTP-induced degeneration in primates.
    Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 348, Issue:6

    Topics: Animals; Behavior, Animal; Biogenic Monoamines; Callithrix; Female; Immunohistochemistry; Male; MPTP

1993
Selective excitotoxic pathology in the rat hippocampus.
    Neuropathology and applied neurobiology, 1993, Volume: 19, Issue:5

    Topics: Animals; Brain; Brain Damage, Chronic; Cell Death; Hippocampus; Ibotenic Acid; Kainic Acid; Male; N-

1993
Traumatic brain damage prevented by the non-N-methyl-D-aspartate antagonist 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo[f] quinoxaline.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, May-28, Volume: 93, Issue:11

    Topics: Animals; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Excitatory Amino Acid Antagonists;

1996
N-Methyl-D-aspartate antagonists and apoptotic cell death triggered by head trauma in developing rat brain.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Mar-02, Volume: 96, Issue:5

    Topics: Animals; Apoptosis; Brain; Brain Injuries; Caudate Nucleus; Disease Models, Animal; Dizocilpine Male

1999
Time dependence and role of N-methyl-D-aspartate glutamate receptors in the priming of D2-mediated rotational behavior and striatal Fos expression in 6-hydroxydopamine lesioned rats.
    Brain research, 1999, May-08, Volume: 827, Issue:1-2

    Topics: Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Corpus Striatum; Dizocilpine Maleate; Dopam

1999
Interleukin-1beta immunoreactivity and microglia are enhanced in the rat hippocampus by focal kainate application: functional evidence for enhancement of electrographic seizures.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Jun-15, Volume: 19, Issue:12

    Topics: Animals; Antibodies; Anticonvulsants; Antirheumatic Agents; Bicuculline; Cell Count; Electroencephal

1999
Inhibition of kainic acid induced expression of interleukin-1 beta and interleukin-1 receptor antagonist mRNA in the rat brain by NMDA receptor antagonists.
    Brain research. Molecular brain research, 2000, Dec-28, Volume: 85, Issue:1-2

    Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Epilepsies, Myoclonic; Excitatory Amino Acid Agonist

2000
An investigation of the mechanisms of delayed neurodegeneration caused by direct injection of quinolinate into the rat striatum in vivo.
    Neuroscience, 1991, Volume: 42, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Anticonvulsants; Convulsants; Corpus Striatum; Dialysis; Diaz

1991
Hypoglycemic neurotoxicity in vitro: involvement of excitatory amino acid receptors and attenuation by monosialoganglioside GM1.
    Neuroscience, 1990, Volume: 37, Issue:3

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cerebellum; G(M1) Ganglioside; Gangliosides; Hypoglyc

1990
Neuroprotective effects of MK-801 in vivo: selectivity and evidence for delayed degeneration mediated by NMDA receptor activation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1988, Volume: 8, Issue:12

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Aspartic Acid; Brain;

1988