3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid has been researched along with Infarction, Middle Cerebral Artery in 2 studies
3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid: structure given in first source; NMDA receptor antagonist
Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Taken together, the results suggest that middle cerebral artery occlusion resulted in synthesis of estrogen within the central nucleus of the amygdala and that this enhanced estrogen level may act to attenuate overstimulation of central nucleus of the amygdala neurons to prevent middle cerebral artery occlusion-induced autonomic dysfunction." | 1.33 | Estrogen synthesis in the central nucleus of the amygdala following middle cerebral artery occlusion: role in modulating neurotransmission. ( Connell, BJ; Cribb, AE; Legge, C; Saleh, TM, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baudy, RB | 1 |
| Fletcher, H | 1 |
| Yardley, JP | 1 |
| Zaleska, MM | 1 |
| Bramlett, DR | 1 |
| Tasse, RP | 1 |
| Kowal, DM | 1 |
| Katz, AH | 1 |
| Moyer, JA | 1 |
| Abou-Gharbia, M | 1 |
| Saleh, TM | 1 |
| Connell, BJ | 1 |
| Legge, C | 1 |
| Cribb, AE | 1 |
2 other studies available for 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Design, synthesis, SAR, and biological evaluation of highly potent benzimidazole-spaced phosphono-alpha-amino acid competitive NMDA antagonists of the AP-6 type.
Topics: Animals; Arterial Occlusive Diseases; Benzimidazoles; Binding, Competitive; Brain; Carotid Artery Di | 2001 |
Estrogen synthesis in the central nucleus of the amygdala following middle cerebral artery occlusion: role in modulating neurotransmission.
Topics: Amygdala; Animals; Aromatase Inhibitors; Autonomic Nervous System; Blood Pressure; Brain Chemistry; | 2005 |