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3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid and Apnea

3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid has been researched along with Apnea in 2 studies

3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid: structure given in first source; NMDA receptor antagonist

Apnea: A transient absence of spontaneous respiration.

Research Excerpts

ExcerptRelevanceReference
" Activation of NMDA receptors at the ventrolateral nucleus of the tractus solitarius with bilateral microinjection of NMDA, 39 pmol, produced a large increase in expiratory duration (+11 +/- 3 s, n = 8), and apnea during the expiratory phase of the respiratory cycle in half of the animals studied."3.69NMDA receptors are involved at the ventrolateral nucleus tractus solitarii for termination of inspiration. ( Berger, I; Gillis, RA; Kelly, M; Magee, S; McManigle, JE; Norman, WP; Panico, WH; Taveira DaSilva, AM; Vitagliano, S, 1995)
"5 nmol of L-glutamate into the caudal subretrofacial area produced apnea in eight of eight animals tested, and the duration of apnea was 27 +/- 2 s."3.69Respiratory effects produced by microinjection of L-glutamate and an uptake inhibitor of L-glutamate into the caudal subretrofacial area of the medulla. ( DaSilva, AM; Gillis, RA; McManigle, JE; Panico, WH, 1995)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berger, I1
Gillis, RA2
Vitagliano, S1
Panico, WH2
Magee, S1
Kelly, M1
Norman, WP1
McManigle, JE2
Taveira DaSilva, AM1
DaSilva, AM1

Other Studies

2 other studies available for 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid and Apnea

ArticleYear
NMDA receptors are involved at the ventrolateral nucleus tractus solitarii for termination of inspiration.
    European journal of pharmacology, 1995, Apr-24, Volume: 277, Issue:2-3

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-

1995
Respiratory effects produced by microinjection of L-glutamate and an uptake inhibitor of L-glutamate into the caudal subretrofacial area of the medulla.
    European journal of pharmacology, 1995, Jul-14, Volume: 280, Issue:3

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Apnea; Blood Pressure; Cats; Cycloleucine; Dicarboxyl

1995