3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid has been researched along with Aging in 14 studies
3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid: structure given in first source; NMDA receptor antagonist
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the effect of nicotine, a nicotinic agonist, and D-cycloserine (DCS, a partial glycine-B agonist of the N-methyl-D-aspartate (NMDA) receptor complex) on aging-induced defects of water maze (WM) spatial navigation in rats." | 3.69 | Nicotine and D-cycloserine enhance acquisition of water maze spatial navigation in aged rats. ( Riekkinen, M; Riekkinen, P, 1997) |
| "[3H]-glycine binding sites were severely decreased in the telencephalic regions, including the hippocampus and cerebral cortex, in aged brain." | 1.28 | Influence of age on NMDA receptor complex in rat brain studied by in vitro autoradiography. ( Kito, S; Miyoshi, R; Nomoto, T, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (71.43) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kouvaros, S | 1 |
| Kotzadimitriou, D | 1 |
| Papatheodoropoulos, C | 1 |
| Ma, CL | 1 |
| Kelly, JB | 1 |
| Wu, SH | 1 |
| Dieguez, D | 1 |
| Barea-Rodriguez, EJ | 1 |
| Fueta, Y | 1 |
| Avoli, M | 3 |
| Louvel, J | 1 |
| Kurcewicz, I | 1 |
| Pumain, R | 1 |
| Barbarosie, M | 1 |
| Riekkinen, M | 2 |
| Riekkinen, P | 2 |
| Psarropoulou, C | 2 |
| Descombes, S | 1 |
| Magnusson, KR | 1 |
| Aamodt, SM | 1 |
| Kozlowski, MR | 1 |
| Nordeen, EJ | 1 |
| Nordeen, KW | 1 |
| Miyoshi, R | 2 |
| Kito, S | 2 |
| Doudou, N | 1 |
| Nomoto, T | 2 |
| Erdö, SL | 1 |
| Wolff, JR | 1 |
14 other studies available for 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid and Aging
| Article | Year |
|---|---|
Hippocampal sharp waves and ripples: Effects of aging and modulation by NMDA receptors and L-type Ca2+ channels.
Topics: Action Potentials; Aging; Animals; Biophysics; Calcium Channel Blockers; Calcium Channels, L-Type; D | 2015 |
AMPA and NMDA receptors mediate synaptic excitation in the rat's inferior colliculus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Excitatory Amino | 2002 |
Aging impairs the late phase of long-term potentiation at the medial perforant path-CA3 synapse in awake rats.
Topics: Aging; Animals; Arousal; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsyn | 2004 |
Tetraethylammonium-induced epileptiform activity in young and adult rat hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Bicuculline; Dose-Response Relationship, Drug; | 1993 |
Extracellular free potassium and calcium during synchronous activity induced by 4-aminopyridine in the juvenile rat hippocampus.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Analgesics; Animals; Calcium; Electrop | 1996 |
Dorsal hippocampal muscarinic acetylcholine and NMDA receptors disrupt water maze navigation.
Topics: Aging; Analysis of Variance; Animals; Excitatory Amino Acid Antagonists; Hippocampus; Infusions, Par | 1997 |
Nicotine and D-cycloserine enhance acquisition of water maze spatial navigation in aged rats.
Topics: Aging; Analysis of Variance; Animals; Cycloserine; Excitatory Amino Acid Antagonists; Male; Maze Lea | 1997 |
Differential bicuculline-induced epileptogenesis in rat neonatal, juvenile and adult CA3 pyramidal neurons in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Aging; Animals; Animals, Newborn; Bicuculli | 1999 |
Declines in mRNA expression of different subunits may account for differential effects of aging on agonist and antagonist binding to the NMDA receptor.
Topics: Aging; Animals; Binding, Competitive; Brain Chemistry; Excitatory Amino Acid Agonists; Excitatory Am | 2000 |
CPP, an NMDA-receptor antagonist, blocks 4-aminopyridine-induced spreading depression episodes but not epileptiform activity in immature rat hippocampal slices.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Animals, Newborn; Anticonvuls | 1992 |
Distribution and developmental change in [3H]MK-801 binding within zebra finch song nuclei.
Topics: Aging; Animals; Auditory Pathways; Autoradiography; Binding, Competitive; Birds; Dizocilpine Maleate | 1992 |
Influence of age on N-methyl-D-aspartate antagonist binding sites in the rat brain studied by in vitro autoradiography.
Topics: Aging; Animals; Autoradiography; Brain; Brain Chemistry; In Vitro Techniques; Kinetics; Male; N-Meth | 1991 |
Influence of age on NMDA receptor complex in rat brain studied by in vitro autoradiography.
Topics: Aging; Animals; Autoradiography; Brain; Cerebral Cortex; Glycine; Hippocampus; Male; Piperazines; Ra | 1990 |
Postnatal development of the excitatory amino acid system in visual cortex of the rat. Changes in ligand binding to NMDA, quisqualate and kainate receptors.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ibotenic Acid; Male; Piper | 1990 |