3-(2,4-dimethoxybenzylidene)anabaseine has been researched along with Disease Models, Animal in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 8 (50.00) | 24.3611 |
| 2020's | 7 (43.75) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, L; Li, J; Wang, L; Xu, F; Zhang, J; Zhang, X | 1 |
| Kang, JL; Kim, DY; Kim, HS; Leem, YH; Park, JE; Park, JS | 1 |
| Chopra, K; Dhaliwal, J; Kondepudi, KK; Ray, RS; Yadav, M; Yadav, S; Yamini, P | 1 |
| Jiang, J; Ma, J; Tang, N; Ye, Z; Zhang, H; Zhao, X; Zhu, Y | 1 |
| Chen, K; Fang, Q; Li, H; Li, XY; Luo, H; Song, XM; Wang, HY; Wang, YL; Wu, XJ; Yan, XT; Yang, XM; Zhang, Y; Zhang, ZZ | 1 |
| Ashby, CR; Gauthier, AG; Lin, M; Mantell, LL; Patel, VS; Sitapara, RA; Zur, M | 1 |
| Jiang, L; Li, F; Li, Q; Liu, X; Sokulsky, L; Tay, HL; Wang, L; Wanyan, Y; Yang, M; Yuan, F; Zhang, G; Zhou, L | 1 |
| Bhakdisongkhram, S; Brenner, T; Hofer, S; Motsch, J; Philipsenburg, C; Schmidt, K; Uhle, F; Weigand, MA; Zivkovic, AR | 1 |
| Al-Sharea, A; Chin-Dusting, J; Flynn, MC; Lee, MKS; Murphy, AJ; Whillas, A | 1 |
| Amamiya, T; Ashihara, E; Ito, A; Kawanishi, S; Kem, WR; Kitade, T; Kitamura, R; Kitamura, Y; Kuroda, E; Mizoguchi, H; Nagasawa, T; Okamoto, H; Saito, Y; Shimohama, S; Sugino, Y; Takata, K; Takegami, S; Tawa, M; Toda, Y | 1 |
| Arias, HR; Hołuj, M; Kos, T; Nikiforuk, A; Popik, P; Potasiewicz, A | 1 |
| Chen, L; He, D; Li, Z; Sokabe, M; Wang, H; Zhang, Z | 1 |
| Cannon, CE; Eddins, D; Egbertson, MS; Puri, V; Uslaner, JM; Vivian, JA | 1 |
| Crombie, J; Farkhondeh, M; Jacobson, L; Kaneki, M; Khan, MA; Martyn, JA | 1 |
| Terry, AV; Wilson, CA | 1 |
| Kem, WR; O'Neill, HC; Rieger, K; Stevens, KE | 1 |
16 other study(ies) available for 3-(2,4-dimethoxybenzylidene)anabaseine and Disease Models, Animal
| Article | Year |
|---|---|
The role of dorsal root ganglia alpha-7 nicotinic acetylcholine receptor in complete Freund's adjuvant-induced chronic inflammatory pain.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzylidene Compounds; Cell Line, Tumor; Chronic Pain; Disease Models, Animal; Freund's Adjuvant; Ganglia, Spinal; Gene Knockdown Techniques; Humans; Inflammation; Inflammation Mediators; Male; Mice; Mice, Inbred C57BL; Neuroinflammatory Diseases; NF-kappa B; Pyridines; TNF Receptor-Associated Factor 6 | 2021 |
Anti-Inflammatory and Neuroprotective Mechanisms of GTS-21, an α7 Nicotinic Acetylcholine Receptor Agonist, in Neuroinflammation and Parkinson's Disease Mouse Models.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents; Benzylidene Compounds; Disease Models, Animal; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Microglia; Neurodegenerative Diseases; Neuroinflammatory Diseases; Neuroprotective Agents; NF-kappa B; Nicotinic Agonists; Parkinson Disease; Phosphatidylinositol 3-Kinases; Pyridines | 2022 |
α7nAChR activation protects against oxidative stress, neuroinflammation and central insulin resistance in ICV-STZ induced sporadic Alzheimer's disease.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Benzylidene Compounds; Cholinergic Agents; Disease Models, Animal; Glycogen Synthase Kinase 3 beta; Insulin Resistance; Maze Learning; Mice; Mice, Inbred C57BL; Oxidative Stress; Proto-Oncogene Proteins c-akt; Pyridines | 2022 |
α7 nicotinic acetylcholine receptor agonist GTS-21 attenuates DSS-induced intestinal colitis by improving intestinal mucosal barrier function.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzylidene Compounds; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Pyridines; Tight Junction Proteins | 2022 |
GTS-21 ameliorates polymicrobial sepsis-induced hepatic injury by modulating autophagy through α7nAchRs in mice.
Topics: Alanine Transaminase; alpha7 Nicotinic Acetylcholine Receptor; Animals; Aspartate Aminotransferases; Autophagy; Benzylidene Compounds; Cytokines; Disease Models, Animal; Inflammation; Interleukin-6; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Pyridines; Sepsis; Tumor Necrosis Factor-alpha | 2020 |
The α7 nicotinic acetylcholine receptor agonist GTS-21 improves bacterial clearance in mice by restoring hyperoxia-compromised macrophage function.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzylidene Compounds; Disease Models, Animal; HMGB1 Protein; Hyperoxia; Macrophages, Alveolar; Male; Mice; Mice, Inbred C57BL; Phagocytosis; Pseudomonas aeruginosa; Pseudomonas Infections; Pyridines; RAW 264.7 Cells; Ventilator-Induced Lung Injury | 2020 |
A Selective α7 Nicotinic Acetylcholine Receptor Agonist, PNU-282987, Attenuates ILC2s Activation and
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Asthma; Benzamides; Benzylidene Compounds; Biomarkers; Bridged Bicyclo Compounds; Cytokines; Disease Models, Animal; Female; Immunity, Innate; Immunohistochemistry; Immunophenotyping; Interleukin-33; Lymphocytes; Mice; Nicotinic Agonists; Pyridines | 2020 |
GTS-21 reduces microvascular permeability during experimental endotoxemia.
Topics: Animals; Benzylidene Compounds; Capillary Permeability; Disease Models, Animal; Endotoxemia; Intravital Microscopy; Lipopolysaccharides; Male; Mesentery; Microvessels; Nicotinic Agonists; Pyridines; Rats, Wistar; Time Factors; Tumor Necrosis Factor-alpha | 2018 |
Nicotinic acetylcholine receptor alpha 7 stimulation dampens splenic myelopoiesis and inhibits atherogenesis in Apoe
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Aorta, Thoracic; Aortic Diseases; Atherosclerosis; Benzylidene Compounds; Diet, Western; Disease Models, Animal; Male; Mice, Knockout, ApoE; Myelopoiesis; Nicotinic Agonists; Plaque, Atherosclerotic; Pyridines; Spleen | 2017 |
Alpha7 nicotinic acetylcholine receptor-specific agonist DMXBA (GTS-21) attenuates Aβ accumulation through suppression of neuronal γ-secretase activity and promotion of microglial amyloid-β phagocytosis and ameliorates cognitive impairment in a mouse mode
Topics: alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Benzylidene Compounds; Brain; Cells, Cultured; Cognitive Dysfunction; Disease Models, Animal; Humans; Mice, Transgenic; Microglia; Neuroblastoma; Phagocytosis; Pyridines; Rats; Tumor Cells, Cultured | 2018 |
3-Furan-2-yl-N-p-tolyl-acrylamide, a positive allosteric modulator of the α7 nicotinic receptor, reverses schizophrenia-like cognitive and social deficits in rats.
Topics: Acrylamides; Allosteric Regulation; alpha7 Nicotinic Acetylcholine Receptor; Animals; Antipsychotic Agents; Attention; Benzylidene Compounds; Cognition; Disease Models, Animal; Furans; Ketamine; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Schizophrenia; Schizophrenic Psychology; Social Behavior | 2017 |
DMXB (GTS-21) ameliorates the cognitive deficits in beta amyloid(25-35(-) ) injected mice through preventing the dysfunction of alpha7 nicotinic receptor.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Animals; Behavior, Animal; Benzylidene Compounds; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Evoked Potentials; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Male; Maze Learning; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 1; Neuronal Plasticity; Nicotinic Agonists; Peptide Fragments; Phosphorylation; Pyridines; Reaction Time; Receptors, Nicotinic; Space Perception | 2010 |
The nicotinic α7 receptor agonist GTS-21 improves cognitive performance in ketamine impaired rhesus monkeys.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Behavior, Animal; Benzylidene Compounds; Cholinesterase Inhibitors; Cognition; Cognition Disorders; Disease Models, Animal; Donepezil; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Indans; Ketamine; Macaca mulatta; Male; Molecular Targeted Therapy; Nicotinic Agonists; Nootropic Agents; Piperidines; Psychomotor Performance; Pyridines; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Schizophrenia | 2013 |
Lipopolysaccharide upregulates α7 acetylcholine receptors: stimulation with GTS-21 mitigates growth arrest of macrophages and improves survival in burned mice.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Analysis of Variance; Animals; Benzylidene Compounds; Bungarotoxins; Burns; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred C57BL; Nicotinic Agonists; Pyridines; Receptors, Nicotinic; RNA, Small Interfering; Tumor Necrosis Factor-alpha | 2012 |
Variable maternal stress in rats alters locomotor activity, social behavior, and recognition memory in the adult offspring.
Topics: Adrenergic Uptake Inhibitors; Amphetamine; Animals; Antipsychotic Agents; Atomoxetine Hydrochloride; Behavior, Animal; Benzylidene Compounds; Disease Models, Animal; Female; Humans; Male; Maze Learning; Mental Disorders; Motor Activity; Nicotinic Agonists; Pregnancy; Prenatal Exposure Delayed Effects; Propylamines; Pyridines; Rats; Rats, Sprague-Dawley; Recognition, Psychology; Risperidone; Social Behavior; Stress, Physiological | 2013 |
DMXB, an alpha7 nicotinic agonist, normalizes auditory gating in isolation-reared rats.
Topics: Animals; Auditory Diseases, Central; Benzylidene Compounds; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Evoked Potentials, Auditory; Male; Nicotinic Agonists; Pyridines; Rats; Rats, Sprague-Dawley; Schizophrenia; Social Isolation; Time Factors | 2003 |