3-(2,4-dimethoxybenzylidene)anabaseine has been researched along with Cognition Disorders in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Buchanan, RW; Christians, U; Freedman, R; Harris, J; Johnson, L; Kem, WR; Olincy, A; Wagner, BD | 1 |
| Bourin, C; Bristow, LJ; Easton, A; Jones, KM; McDonald, IM; Olson, RE | 1 |
| Kong, FJ; Ma, LL; Zhang, HH; Zhou, JQ | 1 |
| Buccafusco, JJ; Terry, AV | 1 |
| Chen, L; He, D; Li, Z; Sokabe, M; Wang, H; Zhang, Z | 1 |
| Freedman, R; Johnson, L; Kem, WR; Leonard, S; Martin, LF; Olincy, A; Rojas, DC; Shatti, S; Soti, F; Tanabe, J; Tregellas, JR | 1 |
| Cannon, CE; Eddins, D; Egbertson, MS; Puri, V; Uslaner, JM; Vivian, JA | 1 |
| Adler, LE; Allensworth, D; Ellis, J; Freedman, R; Harris, JG; Johnson, LL; Kem, WR; Kongs, S; Leonard, S; Martin, L; Olincy, A; Pender, V; Soti, F; Stevens, JO; Stevens, KE; Zerbe, GO | 1 |
| Allensworth, D; Ball, MP; Buchanan, RW; Clement, B; Freedman, R; Gold, JM; Guzman-Bonilla, A; Harris, JG; Johnson, L; Kem, WR; Kutnick, J; Martin, LF; Olincy, A; Pender, V; Soti, F; Stevens, KE; Wagner, BD; Zerbe, GO | 1 |
| Kem, WR; Lin, B; Mahnir, V; Prokai-Tatrai, K | 1 |
| Matsumoto, K; Miyake, H; Murakami, Y; Nanri, M; Watanabe, H | 1 |
4 trial(s) available for 3-(2,4-dimethoxybenzylidene)anabaseine and Cognition Disorders
| Article | Year |
|---|---|
Pharmacokinetic Limitations on Effects of an Alpha7-Nicotinic Receptor Agonist in Schizophrenia: Randomized Trial with an Extended-Release Formulation.
Topics: Adolescent; Adult; alpha7 Nicotinic Acetylcholine Receptor; Antipsychotic Agents; Archaeal Proteins; Benzylidene Compounds; Cognition; Cognition Disorders; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Middle Aged; Nicotinic Agonists; Pyridines; Schizophrenia; Schizophrenic Psychology; Young Adult | 2018 |
Effects of an alpha 7-nicotinic agonist on default network activity in schizophrenia.
Topics: Adult; alpha7 Nicotinic Acetylcholine Receptor; Benzylidene Compounds; Brain; Brain Mapping; Cognition Disorders; Dose-Response Relationship, Drug; Eye Movements; Female; Genotype; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neural Pathways; Nicotinic Agonists; Polymorphism, Single Nucleotide; Pyridines; Receptors, Nicotinic; Schizophrenia | 2011 |
Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia.
Topics: Adult; Benzylidene Compounds; Cognition Disorders; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Evoked Potentials, Auditory; Female; Humans; Male; Neuropsychological Tests; Nicotinic Agonists; Placebos; Psychiatric Status Rating Scales; Pyridines; Receptors, Nicotinic; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index | 2006 |
Initial phase 2 trial of a nicotinic agonist in schizophrenia.
Topics: Adult; Attention; Benzylidene Compounds; Brief Psychiatric Rating Scale; Cognition Disorders; Drug Administration Schedule; Female; Humans; Male; Memory, Short-Term; Middle Aged; Neuropsychological Tests; Nicotinic Agonists; Pyridines; Receptors, Cholinergic; Receptors, Nicotinic; Schizophrenia; Severity of Illness Index | 2008 |
7 other study(ies) available for 3-(2,4-dimethoxybenzylidene)anabaseine and Cognition Disorders
| Article | Year |
|---|---|
Effect of alpha7 nicotinic acetylcholine receptor agonists on attentional set-shifting impairment in rats.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Antipsychotic Agents; Attention; Benzamides; Benzylidene Compounds; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Clozapine; Cognition Disorders; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Discovery; Male; Maze Learning; Neuropsychological Tests; Pyridines; Rats; Rats, Sprague-Dawley; Schizophrenia; Set, Psychology | 2014 |
Alpha 7 nicotinic acetylcholine receptor agonist GTS-21 mitigates isoflurane-induced cognitive impairment in aged rats.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Benzylidene Compounds; Cognition Disorders; Hippocampus; Interleukin-1beta; Isoflurane; Male; Nicotinic Agonists; Pyridines; Rats; Rats, Sprague-Dawley | 2015 |
A reversible model of the cognitive impairment associated with schizophrenia in monkeys: potential therapeutic effects of two nicotinic acetylcholine receptor agonists.
Topics: Animals; Antipsychotic Agents; Benzylidene Compounds; Cognition Disorders; Conditioning, Operant; Cotinine; Female; Hallucinogens; Ketamine; Macaca nemestrina; Male; Memory; Nicotinic Agonists; Pyridines; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology | 2009 |
DMXB (GTS-21) ameliorates the cognitive deficits in beta amyloid(25-35(-) ) injected mice through preventing the dysfunction of alpha7 nicotinic receptor.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Animals; Behavior, Animal; Benzylidene Compounds; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Evoked Potentials; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Male; Maze Learning; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 1; Neuronal Plasticity; Nicotinic Agonists; Peptide Fragments; Phosphorylation; Pyridines; Reaction Time; Receptors, Nicotinic; Space Perception | 2010 |
The nicotinic α7 receptor agonist GTS-21 improves cognitive performance in ketamine impaired rhesus monkeys.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Behavior, Animal; Benzylidene Compounds; Cholinesterase Inhibitors; Cognition; Cognition Disorders; Disease Models, Animal; Donepezil; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Indans; Ketamine; Macaca mulatta; Male; Molecular Targeted Therapy; Nicotinic Agonists; Nootropic Agents; Piperidines; Psychomotor Performance; Pyridines; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Schizophrenia | 2013 |
Pharmacokinetics and urinary excretion of DMXBA (GTS-21), a compound enhancing cognition.
Topics: Animals; Benzylidene Compounds; Brain; Chromatography, High Pressure Liquid; Cognition Disorders; Male; Nicotinic Agonists; Pyridines; Rats; Rats, Sprague-Dawley | 1998 |
GTS-21, a nicotinic agonist, attenuates multiple infarctions and cognitive deficit caused by permanent occlusion of bilateral common carotid arteries in rats.
Topics: Animals; Benzylidene Compounds; Brain; Carotid Artery, Common; Carotid Stenosis; Cerebral Cortex; Cerebral Infarction; Cognition Disorders; Corpus Striatum; Hippocampus; Male; Maze Learning; Nicotinic Agonists; Pyridines; Rats; Rats, Wistar | 1998 |