3-(2,2,2-trimethylhydrazine)propionate has been researched along with Disease Models, Animal in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 10 (50.00) | 24.3611 |
| 2020's | 6 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cirule, H; Dambrova, M; Kigitovica, D; Korzh, S; Liepinsh, E; Makrecka-Kuka, M; Skride, A; Videja, M; Vilks, K; Vilskersts, R | 1 |
| Drakulić, D; Glumac, S; Jasnić, N; Lakić, I; Pejić, S; Ružičić, A; Stanković, S; Todorović, A; Todorović, Z; Tosti, T; Đorđević, J; Đurašević, S; Đurović, S | 1 |
| Arıkök, AT; Bozkurt, H; Ergüder, Bİ; Gürer, B; Kertmen, H; Kuru Bektaşoğlu, P; Ozaydin, D; Sargon, MF; Türe, D | 1 |
| Akakın, D; Çelikoğlu, E; Demir, D; Gürer, B; Kandemir, C; Koyuncuoğlu, T; Kuru Bektaşoğlu, P; Yeğen, BÇ; Yüksel, M | 1 |
| Bohle, DS; Coderre, TJ; Fulas, OA; Laferriere, A; Stein, RS | 1 |
| Arikok, AT; Bektasoglu, PK; Bozkurt, H; Eser, MT; Gurer, B; Kertmen, H; Ozturk, OC; Sorar, M | 1 |
| Calarco, A; Di Cristo, F; Digilio, FA; Galderisi, U; Melone, MAB; Peluso, G; Rosano, C; Saturnino, C; Sinicropi, MS | 1 |
| D'Apolito, M; Di Cristo, F; Digilio, FA; Finicelli, M; Galderisi, U; Giordano, A; Melone, MAB; Paladino, S; Peluso, G; Saturnino, C; Scialò, F; Valentino, A | 1 |
| Beitnere, U; Jansone, B; Kadish, I; Klusa, V; Kumar, A; van Groen, T | 1 |
| Beitnere, U; Dzirkale, Z; Isajevs, S; Kalvinsh, I; Klusa, V; Pupure, J; Rumaks, J; Svirskis, S | 1 |
| Bonifacio, A; Bouitbir, J; Kaufmann, P; Krähenbühl, S; Roberts, PA; Singh, F; Urwyler, A | 1 |
| Cirule, H; Dambrova, M; Kalvinsh, I; Kuka, J; Liepinsh, E; Veveris, M; Vilskersts, R | 1 |
| Cirule, H; Dambrova, M; Grinberga, S; Kalvinsh, I; Kuka, J; Liepinsh, E; Skapare, E; Svalbe, B; Vilskersts, R; Zvejniece, L | 1 |
| Isajevs, S; Kalvinsh, I; Klusa, V; Pupure, J; Rumaks, J; Skapare, E; Svirina, D; Svirskis, S | 1 |
| Al-Shabanah, OA; Aleisa, AM; Darweesh, AQ; Fatani, AG; Rizwan, L; Sayed-Ahmed, MM | 1 |
| Dambrova, M; Kalvinsh, I; Liepinsh, E; Makrecka, M; Svalbe, B; Zvejniece, L | 1 |
| Beitnere, U; Isajeva, D; Isajevs, S; Jansone, B; Kalvinsh, I; Klusa, V | 1 |
| Duburs, G; Isajevs, S; Kalvinsh, I; Klusa, V; Pupure, J; Rumaks, J; Svirskis, S | 1 |
| Gordjushina, V; Isajevs, S; Kalvinsh, I; Klusa, V; Kratovska, A; Pupure, J; Rumaks, J; Svirskis, S; Taivans, I; Viksna, L | 1 |
| Auer, L; Brooks, H; Krähenbühl, S; Solioz, M; Spaniol, M; Stieger, B; Zimmermann, A | 1 |
1 review(s) available for 3-(2,2,2-trimethylhydrazine)propionate and Disease Models, Animal
| Article | Year |
|---|---|
Mildronate and its neuroregulatory mechanisms: targeting the mitochondria, neuroinflammation, and protein expression.
Topics: Adjuvants, Immunologic; Animals; Disease Models, Animal; Humans; Learning; Methylhydrazines; Mice; Mitochondria; Nerve Regeneration; Nerve Tissue Proteins; Neuritis; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Parkinson Disease; Rats | 2013 |
19 other study(ies) available for 3-(2,2,2-trimethylhydrazine)propionate and Disease Models, Animal
| Article | Year |
|---|---|
Protective Effects of Meldonium in Experimental Models of Cardiovascular Complications with a Potential Application in COVID-19.
Topics: Animals; Cardiotonic Agents; Cardiotoxicity; COVID-19; COVID-19 Drug Treatment; Disease Models, Animal; Endothelium; Heart Failure; Heart Ventricles; Hydrogen Peroxide; Lung; Male; Methylhydrazines; Mice, Inbred C57BL; Mitochondria; Oxygen Saturation; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Stroke Volume; Ventricular Dysfunction, Left; Ventricular Dysfunction, Right | 2021 |
The Effects of a Meldonium Pre-Treatment on the Course of the LPS-Induced Sepsis in Rats.
Topics: Animals; Apoptosis; Disease Models, Animal; Inflammation; Lipopolysaccharides; Male; Methylhydrazines; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sepsis | 2022 |
Mildronate Has Ameliorative Effects on the Experimental Ischemia/Reperfusion Injury Model in the Rabbit Spinal Cord.
Topics: Animals; Antioxidants; Caspase 3; Catalase; Disease Models, Animal; Ischemia; Malondialdehyde; Methylprednisolone; Neuroprotective Agents; Peroxidase; Rabbits; Reperfusion Injury; Spinal Cord; Spinal Cord Ischemia | 2023 |
Neuroprotective effects of mildronate in a rat model of traumatic brain injury.
Topics: Animals; Brain Injuries, Traumatic; Disease Models, Animal; Inflammation; Male; Methylhydrazines; Neuroprotective Agents; Oxidative Stress; Rats | 2019 |
Topical combination of meldonium and N-acetyl cysteine relieves allodynia in rat models of CRPS-1 and peripheral neuropathic pain by enhancing NO-mediated tissue oxygenation.
Topics: Acetylcysteine; Administration, Topical; Animals; Disease Models, Animal; Hyperalgesia; Male; Methylhydrazines; Neuralgia; Nitric Oxide; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Reflex Sympathetic Dystrophy | 2020 |
The Vasorelaxant and Neuroprotective Effects of Mildronate in A Rabbit Subarachnoid Hemorrhage Model.
Topics: Animals; Basilar Artery; Disease Models, Animal; Hippocampus; Male; Methylhydrazines; Neuroprotective Agents; Rabbits; Subarachnoid Hemorrhage; Vasodilator Agents; Vasospasm, Intracranial | 2020 |
The Discovery of Highly Potent THP Derivatives as OCTN2 Inhibitors: From Structure-Based Virtual Screening to In Vivo Biological Activity.
Topics: Animals; Carnitine; Cell Line; Cell Survival; Disease Models, Animal; Drosophila melanogaster; Drug Evaluation, Preclinical; Humans; Huntington Disease; Longevity; Methylhydrazines; Mice; Molecular Docking Simulation; Protein Aggregation, Pathological; Signal Transduction; Solute Carrier Family 22 Member 5; Transfection; Treatment Outcome | 2020 |
Meldonium improves Huntington's disease mitochondrial dysfunction by restoring peroxisome proliferator-activated receptor γ coactivator 1α expression.
Topics: Animals; Animals, Genetically Modified; Cell Death; Cell Line; Culture Media, Serum-Free; Disease Models, Animal; Drosophila; Humans; Huntingtin Protein; Huntington Disease; Methylhydrazines; Mitochondria; Models, Biological; Mutation; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Protein Aggregates; Reactive Oxygen Species; Survival Analysis; Up-Regulation | 2019 |
Mildronate improves cognition and reduces amyloid-β pathology in transgenic Alzheimer's disease mice.
Topics: Acetylcholinesterase; Adjuvants, Immunologic; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Glial Fibrillary Acidic Protein; Glutamate Decarboxylase; Humans; Locomotion; Methylhydrazines; Mice; Mice, Transgenic; Social Behavior | 2014 |
Contractile function and energy metabolism of skeletal muscle in rats with secondary carnitine deficiency.
Topics: Animals; Apoptosis; Biomarkers; Carnitine; Deficiency Diseases; Disease Models, Animal; Energy Metabolism; Glycogenolysis; Male; Methylhydrazines; Muscle Contraction; Muscle Development; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Muscular Atrophy; Random Allocation; Rats, Sprague-Dawley | 2015 |
Myocardial infarct size-limiting and anti-arrhythmic effects of mildronate orotate in the rat heart.
Topics: Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Male; Methylhydrazines; Myocardial Infarction; Necrosis; Orotic Acid; Rats; Rats, Wistar; Reperfusion Injury | 2009 |
Protective effects of mildronate in an experimental model of type 2 diabetes in Goto-Kakizaki rats.
Topics: 3-Hydroxybutyric Acid; Administration, Oral; Animals; Blood Glucose; Cardiovascular Agents; Carnitine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Fructosamine; Heart; Hyperalgesia; Hypoglycemic Agents; In Vitro Techniques; Lipids; Male; Methylhydrazines; Myocardial Ischemia; Pain Threshold; Rats; Rats, Wistar | 2009 |
Neuroprotective properties of mildronate, a mitochondria-targeted small molecule.
Topics: Animals; Anti-HIV Agents; Brain; Caspase 3; Cellular Apoptosis Susceptibility Protein; Disease Models, Animal; Electron Transport Complex IV; Glial Fibrillary Acidic Protein; Lymphocytes; Male; Methylhydrazines; Mice; Mice, Inbred Strains; Neuroprotective Agents; Neurotoxicity Syndromes; Nitric Oxide Synthase Type II; Zidovudine | 2010 |
Carnitine deficiency aggravates cyclophosphamide-induced cardiotoxicity in rats.
Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Animals; Antineoplastic Agents, Alkylating; Cardiomyopathies; Carnitine; Creatine Kinase, MB Form; Cyclophosphamide; Disease Models, Animal; L-Lactate Dehydrogenase; Male; Methylhydrazines; Rats; Rats, Wistar; Risk Factors | 2010 |
Mildronate exerts acute anticonvulsant and antihypnotic effects.
Topics: Alcoholic Intoxication; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Methylhydrazines; Mice; Mice, Inbred ICR; Nitric Oxide; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Seizures; Sleep | 2010 |
Mildronate as a regulator of protein expression in a rat model of Parkinson's disease.
Topics: Animals; Cardiovascular Agents; Corpus Striatum; Disease Models, Animal; Glial Cell Line-Derived Neurotrophic Factor; HSP70 Heat-Shock Proteins; Male; Methylhydrazines; Neural Cell Adhesion Molecules; Neuroprotective Agents; Oxidopamine; Parkinson Disease, Secondary; Protein Biosynthesis; Rats; Rats, Wistar; Substantia Nigra | 2011 |
Search for stroke-protecting agents in endothelin-1-induced ischemic stroke model in rats.
Topics: Animals; Dihydropyridines; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Endothelin-1; Male; Methylhydrazines; Neuroprotective Agents; Rats; Rats, Wistar; Stroke | 2012 |
Protection of azidothymidine-induced cardiopathology in mice by mildronate, a mitochondria-targeted drug.
Topics: Animals; Cardiovascular Agents; Disease Models, Animal; Heart Diseases; Methylhydrazines; Mice; Mice, Inbred ICR; Mitochondria; Zidovudine | 2006 |
Development and characterization of an animal model of carnitine deficiency.
Topics: Animals; Base Sequence; Biological Transport; Carnitine; Carrier Proteins; Disease Models, Animal; DNA Primers; gamma-Butyrobetaine Dioxygenase; Kidney; Kinetics; Male; Membrane Proteins; Methylhydrazines; Microvilli; Mixed Function Oxygenases; Organic Cation Transport Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Solute Carrier Family 22 Member 5; Up-Regulation | 2001 |