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293b cpd and Electrocardiogram QT Prolonged

293b cpd has been researched along with Electrocardiogram QT Prolonged in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (12.50)18.2507
2000's13 (81.25)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Idriss, SF; Neu, WK; Ring, CL1
Ehmke, H; Friederich, P; Kebernik, J; Schwoerer, AP1
Bauer, A; Becker, R; Donahue, JK; Katus, HA; Kelemen, K; Kraft, P; Schoels, W; Senges, JC; Voss, F1
Belardinelli, L; Shryock, JC; Song, Y; Wu, L1
Li, C; Liu, K; Liu, Y; Shi, G; Wang, H; Yang, Z1
Aiba, T; Ding, WG; Horie, M; Inagaki, M; Matsuura, H; Miyoshi, S; Noda, T; Shimizu, W; Sunagawa, K; Toyoda, F; Zankov, DP1
Hashimoto, K; Sugiyama, A; Takahara, A2
Baró, I; Charpentier, F; Escande, D; Kunzelmann, K; Loussouarn, G; Mohammad-Panah, R1
Charpentier, F; Escande, D; Le Marec, H; Merot, J; Riochet, D1
Antzelevitch, C; Shimizu, W2
Barhanin, J; Borsotto, M; Diochot, S; Lazdunski, M; Tinel, N1
Iost, N; Lathrop, DA; Lengyel, C; Papp, JG; Varró, A; Virág, L1
Bogáts, G; Iost, N; Opincariu, M; Papp, JG; Szécsi, J; Szenohradszky, P; Szolnoky, J; Varró, A; Virág, L1
Danilo, P; Gainullin, RZ; Pham, TV; Rosen, MR; Sosunov, EA1

Other Studies

16 other study(ies) available for 293b cpd and Electrocardiogram QT Prolonged

ArticleYear
Variability of action potential duration in pharmacologically induced long QT syndrome type 1.
    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2009, Volume: 2009

    Topics: Action Potentials; Adrenergic Agonists; Animals; Chromans; Electrocardiography; Epinephrine; Heart Ventricles; Linear Models; Long QT Syndrome; Potassium Channel Blockers; Rabbits; Signal Processing, Computer-Assisted; Sulfonamides

2009
The subtype-specific effects of droperidol on action potential duration in cellular and computational models of long QT syndrome.
    Anesthesia and analgesia, 2010, Volume: 111, Issue:3

    Topics: Action Potentials; Adult; Animals; Anti-Arrhythmia Agents; Antiemetics; Cardioplegic Solutions; Cell Separation; Chromans; Computer Simulation; Data Interpretation, Statistical; Droperidol; Guinea Pigs; Humans; Long QT Syndrome; Models, Statistical; Myocytes, Cardiac; Patch-Clamp Techniques; Piperidines; Potassium Channel Blockers; Pyridines; Sulfonamides

2010
Pro- and antiarrhythmic effects of fast cardiac pacing in a canine model of acquired long QT syndrome.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 369, Issue:4

    Topics: Action Potentials; Animals; Cardiac Pacing, Artificial; Chromans; Disease Models, Animal; Dogs; Electrocardiography; Female; Heart Block; Long QT Syndrome; Male; Phenethylamines; Potassium Channel Blockers; Refractory Period, Electrophysiological; Sulfonamides; Time Factors; Ventricular Function

2004
Antagonism by ranolazine of the pro-arrhythmic effects of increasing late INa in guinea pig ventricular myocytes.
    Journal of cardiovascular pharmacology, 2004, Volume: 44, Issue:2

    Topics: Acetanilides; Action Potentials; Animals; Chromans; Cnidarian Venoms; Delayed Rectifier Potassium Channels; Drug Synergism; Drug Therapy, Combination; Female; Guinea Pigs; Heart Conduction System; Heart Ventricles; Ion Channel Gating; Long QT Syndrome; Male; Myocytes, Cardiac; Piperazines; Piperidines; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Potassium Channels, Voltage-Gated; Pyridines; Ranolazine; Sodium Channels; Sulfonamides; Tetrodotoxin; Time Factors

2004
Electrophysiologic effects of nicorandil on the guinea pig long QT1 syndrome model.
    Journal of cardiovascular electrophysiology, 2004, Volume: 15, Issue:7

    Topics: Action Potentials; Animals; Chromans; Disease Models, Animal; Electrocardiography; Guinea Pigs; In Vitro Techniques; Long QT Syndrome; Nicorandil; Potassium Channel Blockers; Sulfonamides; Vasodilator Agents

2004
Cellular and ionic mechanism for drug-induced long QT syndrome and effectiveness of verapamil.
    Journal of the American College of Cardiology, 2005, Jan-18, Volume: 45, Issue:2

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Cats; Chromans; Heart; Long QT Syndrome; Piperidines; Potassium Channel Blockers; Potassium Channels; Pyridines; Sulfonamides; Tissue Culture Techniques; Torsades de Pointes; Verapamil

2005
Reduction of repolarization reserve by halothane anaesthesia sensitizes the guinea-pig heart for drug-induced QT interval prolongation.
    British journal of pharmacology, 2005, Volume: 146, Issue:4

    Topics: Action Potentials; Adrenergic beta-Antagonists; Algorithms; Anesthetics, Inhalation; Animals; Chromans; Delayed Rectifier Potassium Channels; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Electrocardiography; Guinea Pigs; Halothane; Heart; Heart Conduction System; Heart Ventricles; Histamine H1 Antagonists; Linear Models; Long QT Syndrome; Male; Models, Animal; Pharmaceutical Preparations; Potassium Channel Blockers; Reproducibility of Results; Sotalol; Sulfonamides; Terfenadine; Time Factors

2005
Characterization of the halothane-anesthetized guinea-pig heart as a model to detect the K+ channel blocker-induced QT-interval prolongation.
    Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:4

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Anti-Arrhythmia Agents; Chromans; Electrocardiography; Guinea Pigs; Halothane; Heart; Heart Rate; Long QT Syndrome; Male; Potassium Channel Blockers; Sotalol; Sulfonamides

2006
KvLQT1 potassium channel but not IsK is the molecular target for trans-6-cyano-4-(N-ethylsulfonyl-N-methylamino)-3-hydroxy-2,2-dimethyl- chromane.
    Molecular pharmacology, 1997, Volume: 52, Issue:6

    Topics: Animals; Binding Sites; Chromans; COS Cells; Cromakalim; Kinetics; Long QT Syndrome; Potassium; Potassium Channel Blockers; Potassium Channels; Sulfonamides

1997
Adult KCNE1-knockout mice exhibit a mild cardiac cellular phenotype.
    Biochemical and biophysical research communications, 1998, Oct-29, Volume: 251, Issue:3

    Topics: Action Potentials; Animals; Chromans; Electric Conductivity; Electrophysiology; Heart; Homozygote; In Vitro Techniques; KCNQ Potassium Channels; KCNQ1 Potassium Channel; Long QT Syndrome; Mice; Mice, Knockout; Periodicity; Piperidines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Pyridines; Sulfonamides

1998
Differential effects of beta-adrenergic agonists and antagonists in LQT1, LQT2 and LQT3 models of the long QT syndrome.
    Journal of the American College of Cardiology, 2000, Mar-01, Volume: 35, Issue:3

    Topics: Action Potentials; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cardiotonic Agents; Chromans; Cnidarian Venoms; Disease Models, Animal; Dogs; Electrocardiography; Heart Conduction System; Heart Rate; Heart Ventricles; Isoproterenol; Long QT Syndrome; Neurotoxins; Potassium Channel Blockers; Propranolol; Sotalol; Sulfonamides; Sympathetic Nervous System; Treatment Outcome

2000
Effects of a K(+) channel opener to reduce transmural dispersion of repolarization and prevent torsade de pointes in LQT1, LQT2, and LQT3 models of the long-QT syndrome.
    Circulation, 2000, Aug-08, Volume: 102, Issue:6

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Cardiotonic Agents; Chromans; Cnidarian Venoms; Dogs; Electrocardiography; Electrophysiology; Heart; Isoproterenol; Long QT Syndrome; Nicorandil; Potassium Channels; Reaction Time; Sotalol; Sulfonamides; Torsades de Pointes

2000
KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel.
    The EMBO journal, 2000, Dec-01, Volume: 19, Issue:23

    Topics: Animals; Arrhythmias, Cardiac; Cation Transport Proteins; Cell Line; Chromans; COS Cells; DNA-Binding Proteins; Electrophysiology; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; KCNQ Potassium Channels; KCNQ1 Potassium Channel; Long QT Syndrome; Mutation; Myocardium; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Binding; Sulfonamides; Trans-Activators; Transcriptional Regulator ERG; Xenopus

2000
Pharmacological block of the slow component of the outward delayed rectifier current (I(Ks)) fails to lengthen rabbit ventricular muscle QT(c) and action potential duration.
    British journal of pharmacology, 2001, Volume: 132, Issue:1

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Benzodiazepines; Cell Separation; Chromans; Colforsin; Electrocardiography; Female; Heart; Heart Ventricles; In Vitro Techniques; Kinetics; Long QT Syndrome; Male; Microelectrodes; Myocardium; Papillary Muscles; Patch-Clamp Techniques; Piperidines; Potassium Channel Blockers; Pyridines; Rabbits; Sulfonamides

2001
The slow component of the delayed rectifier potassium current in undiseased human ventricular myocytes.
    Cardiovascular research, 2001, Volume: 49, Issue:4

    Topics: Adult; Benzodiazepines; Calcium Channel Blockers; Cell Separation; Chromans; Colforsin; Female; Humans; Ion Channel Gating; Long QT Syndrome; Male; Myocardium; Nisoldipine; Patch-Clamp Techniques; Piperidines; Potassium Channels; Pyridines; Sulfonamides

2001
Impact of sex and gonadal steroids on prolongation of ventricular repolarization and arrhythmias induced by I(K)-blocking drugs.
    Circulation, 2001, May-01, Volume: 103, Issue:17

    Topics: Action Potentials; Animals; Castration; Cation Transport Proteins; Chromans; Dihydrotestosterone; Endocardium; Estradiol; Ether-A-Go-Go Potassium Channels; Female; Isoflavones; Long QT Syndrome; Male; Papillary Muscles; Pericardium; Phenethylamines; Phytoestrogens; Plant Preparations; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Rabbits; Sex Factors; Sulfonamides

2001