27-hydroxycholesterol has been researched along with Xanthomatosis, Cerebrotendinous in 7 studies
*Xanthomatosis, Cerebrotendinous: An autosomal recessive lipid storage disorder due to mutation of the gene CYP27A1 encoding a CHOLESTANETRIOL 26-MONOOXYGENASE. It is characterized by large deposits of CHOLESTEROL and CHOLESTANOL in various tissues resulting in xanthomatous swelling of tendons, early CATARACT, and progressive neurological symptoms. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Y; Fu, X; Lund, EG; MacNaul, KL; Menke, JG; Sparrow, CP; Wright, SD; Zhou, G | 1 |
| Björkhem, I; Del Puppo, M; Dotti, MT; Federico, A; Gallus, GN; Magni, A; Mignarri, A | 1 |
| Liebisch, G; Matysik, S; Pataj, Z; Schmitz, G | 1 |
| Böhm, M; Laufs, U; Lütjohann, D; Weingärtner, O | 1 |
| Björkhem, I; Diczfalusy, U; Movin, T; Papadogiannakis, N; Pikuleva, I; Rönnow, P; von Bahr, S | 1 |
| Björkhem, I; Eggertsen, G; Floren, CH; Hansson, M; Meaney, S; Olin, M; van't Hooft, F; von Bahr, S | 1 |
| Javitt, NB | 1 |
1 review(s) available for 27-hydroxycholesterol and Xanthomatosis, Cerebrotendinous
| Article | Year |
|---|---|
Biologic role(s) of the 25(R),26-hydroxycholesterol metabolic pathway.
Topics: Animals; Arteriosclerosis; Bile Acids and Salts; Cholestanetriol 26-Monooxygenase; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Enzymologic; Humans; Hydroxycholesterols; Mutation; Nervous System Diseases; Stereoisomerism; Steroid Hydroxylases; Xanthomatosis, Cerebrotendinous | 2000 |
6 other study(ies) available for 27-hydroxycholesterol and Xanthomatosis, Cerebrotendinous
| Article | Year |
|---|---|
27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells.
Topics: ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; CCAAT-Enhancer-Binding Proteins; Cells, Cultured; Cholestenones; Cholesterol; Cholesterol, LDL; DNA-Binding Proteins; DNA, Complementary; Dose-Response Relationship, Drug; Fibroblasts; Gas Chromatography-Mass Spectrometry; Humans; Hydroxycholesterols; Ligands; Liver X Receptors; Macrophages; Orphan Nuclear Receptors; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Reverse Transcriptase Polymerase Chain Reaction; Skin; Sterol Regulatory Element Binding Protein 1; Time Factors; Transcription Factors; Transfection; Xanthomatosis, Cerebrotendinous | 2001 |
Evaluation of cholesterol metabolism in cerebrotendinous xanthomatosis.
Topics: Adolescent; Adult; Bile Acids and Salts; Biomarkers; Chenodeoxycholic Acid; Cholestanol; Cholestenones; Cholesterol; Disease Progression; Female; Humans; Hydroxycholesterols; Lipid Metabolism; Male; Middle Aged; Prognosis; Xanthomatosis, Cerebrotendinous; Young Adult | 2016 |
Quantification of oxysterols in human plasma and red blood cells by liquid chromatography high-resolution tandem mass spectrometry.
Topics: Biomarkers; Chromatography, Liquid; Erythrocytes; Humans; Hydroxycholesterols; Ketocholesterols; Niemann-Pick Disease, Type C; Plasma; Stereoisomerism; Tandem Mass Spectrometry; Xanthomatosis, Cerebrotendinous | 2016 |
An alternative pathway of reverse cholesterol transport: the oxysterol 27-hydroxycholesterol.
Topics: Adult; Biological Transport; Cholestanetriol 26-Monooxygenase; Cholesterol; Coronary Disease; Humans; Hydroxycholesterols; Lipoproteins, HDL; Male; Myocardial Infarction; Radiography; Xanthomatosis, Cerebrotendinous | 2010 |
Mechanism of accumulation of cholesterol and cholestanol in tendons and the role of sterol 27-hydroxylase (CYP27A1).
Topics: Adult; Alcoholism; Arteriosclerosis; Blotting, Western; Cells, Cultured; Cholestanetriol 26-Monooxygenase; Cholestanol; Cholesterol; Cytochrome P-450 Enzyme System; Diabetes Complications; Diabetes Mellitus; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydroxycholesterols; Macrophages, Alveolar; Male; Middle Aged; Steroid Hydroxylases; Substrate Specificity; Xanthomatosis, Cerebrotendinous | 2002 |
Unique patient with cerebrotendinous xanthomatosis. Evidence for presence of a defect in a gene that is not identical to sterol 27-hydroxylase.
Topics: Adult; Base Sequence; Cells, Cultured; Cholestanetriol 26-Monooxygenase; Cholestanol; Exons; Female; Humans; Hydroxycholesterols; Mutation; Pedigree; RNA, Messenger; Xanthomatosis, Cerebrotendinous | 2007 |