27-hydroxycholesterol has been researched along with Spastic Paraplegia, Hereditary in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abreu, L; Antenora, A; Arnoldi, A; Baets, J; Bassi, MT; Bauer, P; Bis, DM; Björkhem, I; Criscuolo, C; De Jonghe, P; Deconinck, T; Filla, A; Fischer, I; Fraidakis, MJ; Hauser, S; Höflinger, P; Jägle, C; Jardim, LB; Klopstock, T; Lourenco, CM; Marques, W; Martinuzzi, A; Martus, P; Meisner, C; Paucar, M; Rattay, TW; Saute, JA; Scarlato, M; Schöls, L; Schüle, R; Smets, K; Stendel, C; Wiethoff, S; Züchner, S | 1 |
| Babin, PJ; Banneau, G; Benyounes, I; Castelnovo, G; Coupry, I; Debs, R; Durr, A; Ewenczyk, C; Goizet, C; Guissart, C; Hajage, D; Humbert, L; Labauge, P; Lafourcade, A; Lamari, F; Lavie, J; Lesca, G; Marelli, C; Mochel, F; Monin, ML; Odent, S; Ollagnon, E; Petit, E; Pilliod, J; Rainteau, D; Stevanin, G; Thauvin-Robinet, C; Ullmann, U; Wolf, C | 1 |
| Carecchio, M; Del Puppo, M; Di Bella, D; Dotti, MT; Magistrelli, L; Mignarri, A; Monti, L | 1 |
| Del Puppo, M; Dotti, MT; Federico, A; Ginanneschi, F; Magni, A; Malandrini, A; Mignarri, A; Monti, L; Santorelli, FM; Tessa, A | 2 |
| Björkhem, I; Deng, HX; Donkervoort, S; Hansson, M; Madrid, RE; Schöls, L; Schüle, R; Siddique, N; Siddique, T; Yang, Y | 1 |
| Björkhem, I; Cedazo-Mínguez, A; Folkesson, R; Gil-Bea, FJ; Heverin, M; Ismail, MA; Mateos, L; Schöls, L; Schüle, R | 1 |
2 trial(s) available for 27-hydroxycholesterol and Spastic Paraplegia, Hereditary
| Article | Year |
|---|---|
Hereditary spastic paraplegia type 5: natural history, biomarkers and a randomized controlled trial.
Topics: Adolescent; Adult; Atorvastatin; Biomarkers; Case-Control Studies; Cell Proliferation; Cross-Sectional Studies; Cytochrome P450 Family 7; Disease Progression; Double-Blind Method; Family; Female; Humans; Hydroxycholesterols; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Induced Pluripotent Stem Cells; Male; Middle Aged; Mutation; Neurites; Oxysterols; Pedigree; Severity of Illness Index; Spastic Paraplegia, Hereditary; Steroid Hydroxylases; Young Adult | 2017 |
Plasma oxysterols: biomarkers for diagnosis and treatment in spastic paraplegia type 5.
Topics: Adolescent; Adult; Anticholesteremic Agents; Atorvastatin; Bile Acids and Salts; Child; Cholesterol; Cohort Studies; Cytochrome P450 Family 7; Deoxycholic Acid; Female; Humans; Hydroxycholesterols; Infant; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; Neurologic Examination; Oxysterols; Resveratrol; ROC Curve; Spastic Paraplegia, Hereditary; Steroid Hydroxylases; Young Adult | 2018 |
5 other study(ies) available for 27-hydroxycholesterol and Spastic Paraplegia, Hereditary
| Article | Year |
|---|---|
SPG5 siblings with different phenotypes showing reduction of 27-hydroxycholesterol after simvastatin-ezetimibe treatment.
Topics: Adult; Anticholesteremic Agents; Brain; Cytochrome P450 Family 7; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxycholesterols; Middle Aged; Phenotype; Siblings; Simvastatin; Spastic Paraplegia, Hereditary; Steroid Hydroxylases; Treatment Outcome | 2017 |
Hereditary spastic paraplegia type 5: a potentially treatable disorder of cholesterol metabolism.
Topics: Adult; Anticholesteremic Agents; Cytochrome P450 Family 7; Female; Humans; Hydroxycholesterols; Male; Mutation; Simvastatin; Spastic Paraplegia, Hereditary; Steroid Hydroxylases; Treatment Outcome; Young Adult | 2014 |
Treatment of SPG5 with cholesterol-lowering drugs.
Topics: Anticholesteremic Agents; Ezetimibe; Follow-Up Studies; Humans; Hydroxycholesterols; Siblings; Simvastatin; Spastic Paraplegia, Hereditary | 2015 |
Marked accumulation of 27-hydroxycholesterol in SPG5 patients with hereditary spastic paresis.
Topics: Adult; Bile Acids and Salts; Cytochrome P450 Family 7; Female; Heterozygote; Homozygote; Humans; Hydroxycholesterols; Male; Middle Aged; Neurodegenerative Diseases; Parents; Phosphorylation; Spastic Paraplegia, Hereditary; Steroid Hydroxylases; tau Proteins | 2010 |
Side chain-oxidized oxysterols regulate the brain renin-angiotensin system through a liver X receptor-dependent mechanism.
Topics: Angiotensinogen; Animals; Astrocytes; Brain; Cerebral Cortex; Cholesterol, Dietary; Hippocampus; Humans; Hydroxycholesterols; Liver X Receptors; Mice; Mice, Inbred C57BL; Orphan Nuclear Receptors; Oxidation-Reduction; Rats; Renin-Angiotensin System; Spastic Paraplegia, Hereditary; Up-Regulation | 2011 |