Page last updated: 2024-09-03

27-hydroxycholesterol and Elevated Cholesterol

27-hydroxycholesterol has been researched along with Elevated Cholesterol in 16 studies

Research

Studies (16)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	6 (37.50)	29.6817
2010's	6 (37.50)	24.3611
2020's	4 (25.00)	2.80

Authors

Authors	Studies
Hao, L; Ju, M; Liu, W; Wang, L; Wang, T; Wang, Y; Xiao, R; Zhang, X	1
Asghari, A; Umetani, M	1
Baek, AE; Boppart, MD; Boppart, SA; Das Gupta, A; Deng, YH; Dvoretskiy, SV; Henn, MA; Kong, H; Krawczynska, N; Ma, L; Madak-Erdogan, Z; McDowell, HB; Nelson, AT; Nelson, ER; Park, J; Smith, BP; Sorrells, JE; Sprenger, A; You, S	1
Björkhem, I; Cedazo-Minguez, A; Goikolea, J; Gomes, CM; Ismail, MA; Lodeiro, M; Loera-Valencia, R; Maioli, S; Mateos, L; Merino-Serrais, P; Puerta, E; Romão, MA	1
Bendahl, PO; Borgquist, S; Chang, CY; Dubois, L; Kimbung, S; McDonnell, DP; Thompson, JW	1
Kaiser, J	1
Carver, NJ; Geradts, J; Howe, MK; Jasper, JS; McDonnell, DP; Nelson, ER; Park, S; Pillai, RV; Sondhi, V; Suchindran, S; Sullivan, PM; Umetani, M; Wardell, SE	1
Han, J; Liu, QR; Ma, WW; Wang, H; Xiao, R; Yu, HL; Zhang, DD	1
Agrawal, DK; Pandya, AN; Radwan, MM; Swier, V; Tang, L; Yin, K; You, Y	1
Feist, G; Ghribi, O; Prasanthi R P, J; Schommer, E; Sharma, S	1
Anzivino, C; Baldelli, E; Bertolotti, M; Carulli, L; Carulli, N; Corna, F; Del Puppo, M; Gabbi, C; Galli Kienle, M; Loria, P	1
Laaksonen, R; Lehtimäki, T; Lütjohann, D; Päivä, H; Thelen, KM	1
Björkhem, I; Diczfalusy, U; Heverin, M; Leoni, V; Meaney, S	1
Laaksonen, R; Lehtimaki, T; Luomala, M; Lütjohann, D; Mattila, K; Päivä, H; Saarela, M; Thelen, K	1
Comijs, HC; Dik, MG; Fassbender, K; Jonker, C; Lütjohann, D; van den Kommer, TN	1
Amati, B; Crosignani, A; Del Puppo, M; Galli Kienle, M; Petroni, ML; Podda, M; Zuin, M	1

Reviews

2 review(s) available for 27-hydroxycholesterol and Elevated Cholesterol

Article	Year
Obesity and Cancer: 27-Hydroxycholesterol, the Missing Link. International journal of molecular sciences, 2020, Jul-08, Volume: 21, Issue:14 Topics: Animals; Estrogen Receptor Modulators; Humans; Hydroxycholesterols; Hypercholesterolemia; Neoplasms; Obesity	2020
Oxysterols and Alzheimer's disease. Acta neurologica Scandinavica. Supplementum, 2006, Volume: 185 Topics: Alzheimer Disease; Amyloid beta-Peptides; Blood-Brain Barrier; Brain; Humans; Hydroxycholesterols; Hypercholesterolemia	2006

Trials

1 trial(s) available for 27-hydroxycholesterol and Elevated Cholesterol

Article	Year
Cholesterol metabolism in primary biliary cirrhosis during simvastatin and UDCA administration. Journal of lipid research, 2001, Volume: 42, Issue:3 Topics: Aged; Anticholesteremic Agents; Cholagogues and Choleretics; Cholesterol; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydroxycholesterols; Hypercholesterolemia; Liver Cirrhosis, Biliary; Male; Middle Aged; Simvastatin; Ursodeoxycholic Acid	2001

Article

Year

Cholesterol metabolism in primary biliary cirrhosis during simvastatin and UDCA administration.

Journal of lipid research, 2001, Volume: 42, Issue:3

Topics: Aged; Anticholesteremic Agents; Cholagogues and Choleretics; Cholesterol; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydroxycholesterols; Hypercholesterolemia; Liver Cirrhosis, Biliary; Male; Middle Aged; Simvastatin; Ursodeoxycholic Acid

2001

Other Studies

13 other study(ies) available for 27-hydroxycholesterol and Elevated Cholesterol

Article	Year
High cholesterol and 27-hydroxycholesterol contribute to phosphorylation of tau protein by impairing autophagy causing learning and memory impairment in C57BL/6J mice. The Journal of nutritional biochemistry, 2022, Volume: 106 Topics: Alzheimer Disease; Animals; Autophagy; Cholesterol; Cholesterol, Dietary; Glycogen Synthase Kinase 3 beta; Hydroxycholesterols; Hypercholesterolemia; Male; Mammals; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Phosphorylation; RNA, Small Interfering; tau Proteins; TOR Serine-Threonine Kinases	2022
The Cholesterol Metabolite 27HC Increases Secretion of Extracellular Vesicles Which Promote Breast Cancer Progression. Endocrinology, 2021, 07-01, Volume: 162, Issue:7 Topics: Animals; Cell Line, Tumor; Disease Progression; Estrogen Receptor Modulators; Extracellular Vesicles; Female; Hydroxycholesterols; Hypercholesterolemia; Mammary Neoplasms, Experimental; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Neutrophils; RAW 264.7 Cells	2021
Hypercholesterolemia and 27-Hydroxycholesterol Increase S100A8 and RAGE Expression in the Brain: a Link Between Cholesterol, Alarmins, and Neurodegeneration. Molecular neurobiology, 2021, Volume: 58, Issue:12 Topics: Alarmins; Animals; Astrocytes; Brain; Calgranulin A; Disease Models, Animal; Hydroxycholesterols; Hypercholesterolemia; Mice; Mice, Transgenic; Neurodegenerative Diseases; Neurons; Receptor for Advanced Glycation End Products	2021
Impact of 27-hydroxylase (CYP27A1) and 27-hydroxycholesterol in breast cancer. Endocrine-related cancer, 2017, Volume: 24, Issue:7 Topics: Breast Neoplasms; Cell Line, Tumor; Cholestanetriol 26-Monooxygenase; Cohort Studies; Female; Humans; Hydroxycholesterols; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Middle Aged	2017
Cancer. Cholesterol forges link between obesity and breast cancer. Science (New York, N.Y.), 2013, Nov-29, Volume: 342, Issue:6162 Topics: Animals; Breast Neoplasms; Female; Humans; Hydroxycholesterols; Hypercholesterolemia	2013
27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology. Science (New York, N.Y.), 2013, Nov-29, Volume: 342, Issue:6162 Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cholestanetriol 26-Monooxygenase; Disease Models, Animal; Female; Humans; Hydroxycholesterols; Hypercholesterolemia; Lung Neoplasms; Mice; Tumor Cells, Cultured	2013
27-Hydroxycholesterol contributes to disruptive effects on learning and memory by modulating cholesterol metabolism in the rat brain. Neuroscience, 2015, Aug-06, Volume: 300 Topics: Animals; Blotting, Western; Brain; Cholesterol; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Hydroxycholesterols; Hypercholesterolemia; Hypolipidemic Agents; Immunohistochemistry; Male; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA, Messenger; Spatial Learning; Spatial Memory	2015
Vitamin D Protects Against Atherosclerosis via Regulation of Cholesterol Efflux and Macrophage Polarization in Hypercholesterolemic Swine. Arteriosclerosis, thrombosis, and vascular biology, 2015, Volume: 35, Issue:11 Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Animals; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Biomarkers; Calcifediol; Calcitriol; Cholesterol; Cholesterol, HDL; Disease Models, Animal; Hep G2 Cells; Hepatocytes; Humans; Hydroxycholesterols; Hypercholesterolemia; JNK Mitogen-Activated Protein Kinases; Liver X Receptors; Macrophages; Orphan Nuclear Receptors; Phenotype; Receptors, Calcitriol; Swine; Swine, Miniature; Time Factors; Vitamin D Deficiency	2015
Hypercholesterolemia-induced Abeta accumulation in rabbit brain is associated with alteration in IGF-1 signaling. Neurobiology of disease, 2008, Volume: 32, Issue:3 Topics: Amyloid beta-Peptides; Animals; Cholesterol; Cholesterol, Dietary; Cyclic AMP Response Element-Binding Protein; Enzyme-Linked Immunosorbent Assay; Female; Glycogen Synthase Kinase 3; Hippocampus; Hydroxycholesterols; Hypercholesterolemia; Insulin-Like Growth Factor I; Insulysin; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rabbits; Random Allocation; Signal Transduction	2008
Increased appearance rate of 27-hydroxycholesterol in vivo in hypercholesterolemia: a possible compensatory mechanism. Nutrition, metabolism, and cardiovascular diseases : NMCD, 2012, Volume: 22, Issue:10 Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Case-Control Studies; Cholesterol; Female; Fluorobenzenes; Gas Chromatography-Mass Spectrometry; Heptanoic Acids; Humans; Hydroxycholesterols; Hydroxylation; Hypercholesterolemia; Hyperlipidemia, Familial Combined; Hyperlipoproteinemia Type II; Male; Middle Aged; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Sulfonamides	2012
High-dose statin treatment does not alter plasma marker for brain cholesterol metabolism in patients with moderately elevated plasma cholesterol levels. Journal of clinical pharmacology, 2006, Volume: 46, Issue:7 Topics: Adult; Aged; Atorvastatin; Biomarkers; Brain; Cholesterol; Female; Heptanoic Acids; Humans; Hydroxycholesterols; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pyrroles; Randomized Controlled Trials as Topic; Simvastatin	2006
Osteopontin levels are associated with cholesterol synthesis markers in mildly hypercholesterolaemic patients. Acta cardiologica, 2007, Volume: 62, Issue:2 Topics: Adult; Aged; Analysis of Variance; Apolipoprotein A-I; Apolipoproteins B; Biomarkers; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Enzyme-Linked Immunosorbent Assay; Female; Finland; Humans; Hydroxycholesterols; Hypercholesterolemia; Male; Middle Aged; Muscle, Skeletal; Osteopontin; Phytosterols; Severity of Illness Index; Sex Factors; Triglycerides	2007
Total cholesterol and oxysterols: early markers for cognitive decline in elderly? Neurobiology of aging, 2009, Volume: 30, Issue:4 Topics: Age of Onset; Aged; Aged, 80 and over; Aging; Apolipoprotein E4; Biomarkers; Causality; Cholesterol; Cognition; Cognition Disorders; Female; Genotype; Humans; Hydroxycholesterols; Hypercholesterolemia; Longitudinal Studies; Male; Memory; Memory Disorders; Middle Aged; Neuropsychological Tests; Predictive Value of Tests; Severity of Illness Index	2009