27-hydroxycholesterol has been researched along with Disease Models, Animal in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 13 (68.42) | 24.3611 |
| 2020's | 3 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, X; Jiang, C; Li, Y; Luo, G; Xiao, L; Yao, P; Yu, J; Zeng, H; Zhou, F | 1 |
| Cedazo-Minguez, A; DeFelipe, J; Gerenu, G; Gómez-Galán, M; Lindskog, M; Loera-Valencia, R; Merino-Serrais, P; Muñoz, A; Vazquez-Juarez, E | 1 |
| Björkhem, I; Cedazo-Minguez, A; Goikolea, J; Gomes, CM; Ismail, MA; Lodeiro, M; Loera-Valencia, R; Maioli, S; Mateos, L; Merino-Serrais, P; Puerta, E; Romão, MA | 1 |
| Nelson, ER | 1 |
| An, Y; Liu, W; Tao, L; Wang, T; Wang, Y; Xi, Y; Xiao, R; Yu, H; Zhang, X | 1 |
| Ghribi, O; Marwarha, G; Prasanthi, JR; Raza, S | 1 |
| Brekken, RA; Euhus, DM; Girard, L; Ishikawa, T; McDonald, JG; Mineo, C; Shaul, PW; Sirianni, R; Tang, H; Thompson, B; Umetani, M; Wu, Q; Xie, Y; Yuhanna, IS | 1 |
| Bae, SS; Eo, SK; Kim, BY; Kim, K; Kim, SM; Lee, SA | 1 |
| Carver, NJ; Geradts, J; Howe, MK; Jasper, JS; McDonnell, DP; Nelson, ER; Park, S; Pillai, RV; Sondhi, V; Suchindran, S; Sullivan, PM; Umetani, M; Wardell, SE | 1 |
| Eo, SK; Kim, BY; Kim, CD; Kim, K; Kim, SM; Lee, SA; Yun, Y | 1 |
| Gustafsson, JA; Warner, M | 1 |
| Ghribi, O; Marwarha, G | 1 |
| Bieghs, V; Gijbels, MJ; Guichot, YD; Hendrikx, T; Hofker, MH; Houben, T; Jeurissen, ML; Leitersdorf, E; Lütjohann, D; Shiri-Sverdlov, R; van Gorp, PJ; Verheyen, F; Walenbergh, SM | 1 |
| Chang, CY; McDonnell, DP; Nelson, ER | 1 |
| Eo, SK; Jung, YS; Kim, BY; Kim, K; Kim, SM; Lee, CW; Park, YC | 1 |
| Agrawal, DK; Pandya, AN; Radwan, MM; Swier, V; Tang, L; Yin, K; You, Y | 1 |
| DuSell, CD; McDonnell, DP | 1 |
| De Vries, HE; Dijkstra, CD; Floris, S; Lütjohann, D; Sonke, M; Teunissen, CE | 1 |
| Arnon, R; Budai, K; Javitt, NB; Lefkowitch, JH; Reiss, A; Yoshimura, T | 1 |
2 review(s) available for 27-hydroxycholesterol and Disease Models, Animal
| Article | Year |
|---|---|
The significance of cholesterol and its metabolite, 27-hydroxycholesterol in breast cancer.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cholesterol; Disease Models, Animal; Female; Humans; Hydroxycholesterols; Mice; Neoplasm Recurrence, Local; Prognosis; Receptors, Estrogen | 2018 |
Does the oxysterol 27-hydroxycholesterol underlie Alzheimer's disease-Parkinson's disease overlap?
Topics: alpha-Synuclein; Alzheimer Disease; Animals; Brain; Cholesterol, Dietary; Disease Models, Animal; Endoplasmic Reticulum Stress; Homeostasis; Humans; Hydroxycholesterols; Lipid Metabolism; Liver X Receptors; Orphan Nuclear Receptors; Parkinson Disease; Plaque, Amyloid; Rabbits | 2015 |
17 other study(ies) available for 27-hydroxycholesterol and Disease Models, Animal
| Article | Year |
|---|---|
Macrophage iron retention aggravates atherosclerosis: Evidence for the role of autocrine formation of hepcidin in plaque macrophages.
Topics: Aged; Animals; Atherosclerosis; Autocrine Communication; Carotid Arteries; Cholestanetriol 26-Monooxygenase; Cholesterol, LDL; Diet, High-Fat; Disease Models, Animal; Endarterectomy, Carotid; Female; Foam Cells; Hepcidins; Humans; Hydroxycholesterols; Iron; Lipoproteins, LDL; Male; Mice; Mice, Knockout, ApoE; Middle Aged; NF-kappa B; Plaque, Atherosclerotic; RAW 264.7 Cells; Signal Transduction; Toll-Like Receptor 4 | 2020 |
High levels of 27-hydroxycholesterol results in synaptic plasticity alterations in the hippocampus.
Topics: Alzheimer Disease; Animals; CA1 Region, Hippocampal; Cognitive Dysfunction; Dendritic Spines; Disease Models, Animal; Hippocampus; Humans; Hydroxycholesterols; Long-Term Potentiation; Male; Mice; Mice, Transgenic; Microfilament Proteins; Neuronal Plasticity; Pyramidal Cells; Synapses; Synaptic Transmission | 2021 |
Hypercholesterolemia and 27-Hydroxycholesterol Increase S100A8 and RAGE Expression in the Brain: a Link Between Cholesterol, Alarmins, and Neurodegeneration.
Topics: Alarmins; Animals; Astrocytes; Brain; Calgranulin A; Disease Models, Animal; Hydroxycholesterols; Hypercholesterolemia; Mice; Mice, Transgenic; Neurodegenerative Diseases; Neurons; Receptor for Advanced Glycation End Products | 2021 |
27-hydroxycholesterol promotes Aβ accumulation via altering Aβ metabolism in mild cognitive impairment patients and APP/PS1 mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Brain; Case-Control Studies; Cognitive Dysfunction; Disease Models, Animal; Hippocampus; Humans; Hydroxycholesterols; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Peptide Fragments; Plaque, Amyloid; Presenilin-1 | 2019 |
Gadd153 and NF-κB crosstalk regulates 27-hydroxycholesterol-induced increase in BACE1 and β-amyloid production in human neuroblastoma SH-SY5Y cells.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Cell Line, Tumor; Disease Models, Animal; Gene Expression Regulation; Humans; Hydroxycholesterols; Male; Mice; Mice, Transgenic; Neurons; NF-kappa B; Promoter Regions, Genetic; Protein Binding; RNA, Small Interfering; Signal Transduction; Transcription Factor CHOP; Transcription, Genetic | 2013 |
27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth.
Topics: Animals; Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Cytochrome P450 Family 7; Disease Models, Animal; Female; Gene Expression; Heterografts; Humans; Hydroxycholesterols; MCF-7 Cells; Mice; Mice, SCID; Receptors, Estrogen; Signal Transduction; Steroid Hydroxylases | 2013 |
27-Hydroxycholesterol induces recruitment of monocytic cells by enhancing CCL2 production.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Cell Line; Chemokine CCL2; Chemotaxis, Leukocyte; Cholesterol, Dietary; Disease Models, Animal; Humans; Hydroxycholesterols; Lipoproteins, LDL; Liver X Receptors; Mice; Mice, Mutant Strains; Monocytes; Orphan Nuclear Receptors; Proto-Oncogene Proteins c-akt | 2013 |
27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cholestanetriol 26-Monooxygenase; Disease Models, Animal; Female; Humans; Hydroxycholesterols; Hypercholesterolemia; Lung Neoplasms; Mice; Tumor Cells, Cultured | 2013 |
27-Hydroxycholesterol and 7alpha-hydroxycholesterol trigger a sequence of events leading to migration of CCR5-expressing Th1 lymphocytes.
Topics: Animals; Cell Line, Tumor; Cell Movement; Chemokine CCL3; Chemokine CCL4; Cholesterol; Diet, High-Fat; Disease Models, Animal; Humans; Hydroxycholesterols; Jurkat Cells; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptors, CCR5; Signal Transduction; Th1 Cells; Up-Regulation | 2014 |
On estrogen, cholesterol metabolism, and breast cancer.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cholestanetriol 26-Monooxygenase; Cholesterol; Disease Models, Animal; Estradiol; Estrogens; Female; Humans; Hydroxycholesterols; Lung Neoplasms; Mice | 2014 |
Hematopoietic overexpression of Cyp27a1 reduces hepatic inflammation independently of 27-hydroxycholesterol levels in Ldlr(-/-) mice.
Topics: Animals; Bone Marrow Transplantation; Cholestanetriol 26-Monooxygenase; Disease Models, Animal; DNA; Gene Expression Regulation; Hydroxycholesterols; Kupffer Cells; Lipoproteins, LDL; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease | 2015 |
The estrogen receptor as a mediator of the pathological actions of cholesterol in breast cancer.
Topics: Animals; Autocrine Communication; Breast Neoplasms; Cholesterol; Cholesterol, Dietary; Disease Models, Animal; Estrogen Receptor alpha; Female; Humans; Hydroxycholesterols; Hyperlipidemias; Incidence; Neoplasm Recurrence, Local; Obesity; Paracrine Communication; Receptors, Estrogen; Risk Factors; Selective Estrogen Receptor Modulators | 2014 |
27-Oxygenated cholesterol induces expression of CXCL8 in macrophages via NF-κB and CD88.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Chemokine CCL2; Disease Models, Animal; Hydroxycholesterols; Interleukin-8; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Receptor, Anaphylatoxin C5a; Transcription, Genetic | 2015 |
Vitamin D Protects Against Atherosclerosis via Regulation of Cholesterol Efflux and Macrophage Polarization in Hypercholesterolemic Swine.
Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Animals; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Biomarkers; Calcifediol; Calcitriol; Cholesterol; Cholesterol, HDL; Disease Models, Animal; Hep G2 Cells; Hepatocytes; Humans; Hydroxycholesterols; Hypercholesterolemia; JNK Mitogen-Activated Protein Kinases; Liver X Receptors; Macrophages; Orphan Nuclear Receptors; Phenotype; Receptors, Calcitriol; Swine; Swine, Miniature; Time Factors; Vitamin D Deficiency | 2015 |
27-Hydroxycholesterol: a potential endogenous regulator of estrogen receptor signaling.
Topics: Animals; Breast Neoplasms; Cardiovascular Diseases; Cholesterol; Disease Models, Animal; Humans; Hydroxycholesterols; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Signal Transduction; Transcription, Genetic | 2008 |
24S-hydroxycholesterol in relation to disease manifestations of acute experimental autoimmune encephalomyelitis.
Topics: Acute Disease; Animals; Biomarkers; Cholesterol; Cholesterol 24-Hydroxylase; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Hydroxycholesterols; Macrophages; Male; Multiple Sclerosis; Rats; Rats, Inbred Lew; Steroid Hydroxylases | 2007 |
Cholesterol 7-hydroxylase knockout mouse: a model for monohydroxy bile acid-related neonatal cholestasis.
Topics: Animals; Animals, Newborn; Bile Acids and Salts; Bile Canaliculi; Cholestasis; Cholic Acids; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Hydroxycholesterols; Lithocholic Acid; Liver; Mice; Mice, Mutant Strains; Reference Values; RNA, Messenger; Spleen; Steroid 12-alpha-Hydroxylase | 1998 |