Page last updated: 2024-09-03

27-hydroxycholesterol and Cognitive Dysfunction

27-hydroxycholesterol has been researched along with Cognitive Dysfunction in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (55.56)24.3611
2020's4 (44.44)2.80

Authors

AuthorsStudies
Feng, W; Hao, L; Ju, M; Wang, L; Xiao, R; Yu, H1
An, Y; Liu, W; Lu, Y; Ma, W; Wang, T; Wang, Y; Xiao, R; Yu, H; Zhang, X1
Cedazo-Minguez, A; DeFelipe, J; Gerenu, G; Gómez-Galán, M; Lindskog, M; Loera-Valencia, R; Merino-Serrais, P; Muñoz, A; Vazquez-Juarez, E1
Björkhem, I; Cedazo-Minguez, A; Goikolea, J; Kemppainen, N; Kivipelto, M; Laatikainen, T; Ngandu, T; Paternain, L; Rinne, J; Sandebring-Matton, A; Soininen, H; Solomon, A1
He, S; Nelson, ER1
An, Y; Liu, W; Tao, L; Wang, T; Wang, Y; Xi, Y; Xiao, R; Yu, H; Zhang, X1
Kuo, SH; Liu, N; Liu, XG; Song, QY; Wang, HL; Wang, MW; Wang, YY1
An, Y; Feng, L; Liu, Q; Lu, Y; Wang, C; Xiao, R; Yu, H1
Björkhem, I; Cedazo-Mínguez, A; Gil-Bea, FJ; Ismail, MA; Leoni, V; Mateos, L; Winblad, B1

Reviews

2 review(s) available for 27-hydroxycholesterol and Cognitive Dysfunction

ArticleYear
27-Hydroxycholesterol, an endogenous selective estrogen receptor modulator.
    Maturitas, 2017, Volume: 104

    Topics: Animals; Atherosclerosis; Breast Neoplasms; Cognitive Dysfunction; Female; Humans; Hydroxycholesterols; Male; Osteoporosis; Prostatic Neoplasms; Receptors, Estrogen; Selective Estrogen Receptor Modulators

2017
Cholesterol, 24-Hydroxycholesterol, and 27-Hydroxycholesterol as Surrogate Biomarkers in Cerebrospinal Fluid in Mild Cognitive Impairment and Alzheimer's Disease: A Meta-Analysis.
    Journal of Alzheimer's disease : JAD, 2016, Volume: 51, Issue:1

    Topics: Alzheimer Disease; Cholesterol; Cognitive Dysfunction; Databases, Bibliographic; Humans; Hydroxycholesterols

2016

Trials

1 trial(s) available for 27-hydroxycholesterol and Cognitive Dysfunction

ArticleYear
27-Hydroxycholesterol, cognition, and brain imaging markers in the FINGER randomized controlled trial.
    Alzheimer's research & therapy, 2021, 03-06, Volume: 13, Issue:1

    Topics: Aged; Brain; Cognition; Cognitive Dysfunction; Cross-Sectional Studies; Finland; Humans; Hydroxycholesterols; Magnetic Resonance Imaging; Neuroimaging; Neuropsychological Tests

2021

Other Studies

6 other study(ies) available for 27-hydroxycholesterol and Cognitive Dysfunction

ArticleYear
The Interaction Effect of 27-Hydroxycholesterol Metabolism Disorder and CYP27A1 Single Nucleotide Polymorphisms in Mild Cognitive Impairment: Evidence from a Case-Control Study.
    Molecular nutrition & food research, 2023, Volume: 67, Issue:10

    Topics: Alzheimer Disease; Case-Control Studies; Cholestanetriol 26-Monooxygenase; Cognitive Dysfunction; Cytochrome P-450 Enzyme System; Humans; Hydroxycholesterols; Polymorphism, Single Nucleotide

2023
27-Hydroxycholesterol contributes to cognitive deficits in APP/PS1 transgenic mice through microbiota dysbiosis and intestinal barrier dysfunction.
    Journal of neuroinflammation, 2020, Jun-27, Volume: 17, Issue:1

    Topics: Anastrozole; Animals; Aromatase Inhibitors; Avoidance Learning; Cognitive Dysfunction; Dysbiosis; Gastrointestinal Microbiome; Hydroxycholesterols; Intestinal Mucosa; Intestines; Male; Maze Learning; Mice; Mice, Transgenic; Tight Junction Proteins; Tight Junctions

2020
High levels of 27-hydroxycholesterol results in synaptic plasticity alterations in the hippocampus.
    Scientific reports, 2021, 02-12, Volume: 11, Issue:1

    Topics: Alzheimer Disease; Animals; CA1 Region, Hippocampal; Cognitive Dysfunction; Dendritic Spines; Disease Models, Animal; Hippocampus; Humans; Hydroxycholesterols; Long-Term Potentiation; Male; Mice; Mice, Transgenic; Microfilament Proteins; Neuronal Plasticity; Pyramidal Cells; Synapses; Synaptic Transmission

2021
27-hydroxycholesterol promotes Aβ accumulation via altering Aβ metabolism in mild cognitive impairment patients and APP/PS1 mice.
    Brain pathology (Zurich, Switzerland), 2019, Volume: 29, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Brain; Case-Control Studies; Cognitive Dysfunction; Disease Models, Animal; Hippocampus; Humans; Hydroxycholesterols; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Peptide Fragments; Plaque, Amyloid; Presenilin-1

2019
Relationship between oxysterols and mild cognitive impairment in the elderly: a case-control study.
    Lipids in health and disease, 2016, Oct-10, Volume: 15, Issue:1

    Topics: Aged; Alzheimer Disease; Chromatography, High Pressure Liquid; Cognitive Dysfunction; Female; Humans; Hydroxycholesterols; Male; Mass Spectrometry; Middle Aged

2016
Upregulation of brain renin angiotensin system by 27-hydroxycholesterol in Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2011, Volume: 24, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Angiotensinogen; Animals; Biomarkers; Brain Chemistry; Cells, Cultured; Cognitive Dysfunction; Cross-Sectional Studies; Female; Humans; Hydroxycholesterols; Male; Middle Aged; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Up-Regulation

2011