25-hydroxyvitamin-d-2 and Congenital-Hypothyroidism

25-hydroxyvitamin-d-2 has been researched along with Congenital-Hypothyroidism* in 2 studies

Trials

1 trial(s) available for 25-hydroxyvitamin-d-2 and Congenital-Hypothyroidism

Article	Year
Hypercalcemia in infants with congenital hypothyroidism and its relation to vitamin D and thyroid hormones. The Journal of pediatrics, 1986, Volume: 109, Issue:5 The circulating concentrations of calcium, phosphorus, and vitamin D metabolites were measured in 25 infants (fifteen to 30 days of age) with congenital hypothyroidism before treatment or during the first 6 months of thyroxine therapy. Five of the children before treatment and four during the early 3 months of treatment had mild hypercalcemia (10.8 to 12.4 mg/dl). Hypercalcemia before treatment did not appear to be related to the vitamin D status of the infant nor to an alteration in vitamin D metabolism, but to the presence of a residual thyroid secretion. In contrast, hypercalcemia during thyroxine therapy was related to vitamin D supplementation, even though the serum calcium concentration could not be correlated with the circulating concentration of any of the vitamin D metabolites assayed and obvious changes in vitamin D metabolism could not be demonstrated. Topics: 24,25-Dihydroxyvitamin D 3; 25-Hydroxyvitamin D 2; Alkaline Phosphatase; Calcitriol; Calcium; Congenital Hypothyroidism; Dihydroxycholecalciferols; Ergocalciferols; Humans; Hypercalcemia; Hypothyroidism; Infant, Newborn; Phosphorus; Thyroid Hormones; Thyrotropin; Thyroxine; Time Factors; Vitamin D	1986

Article

Year

Hypercalcemia in infants with congenital hypothyroidism and its relation to vitamin D and thyroid hormones.

The Journal of pediatrics, 1986, Volume: 109, Issue:5

The circulating concentrations of calcium, phosphorus, and vitamin D metabolites were measured in 25 infants (fifteen to 30 days of age) with congenital hypothyroidism before treatment or during the first 6 months of thyroxine therapy. Five of the children before treatment and four during the early 3 months of treatment had mild hypercalcemia (10.8 to 12.4 mg/dl). Hypercalcemia before treatment did not appear to be related to the vitamin D status of the infant nor to an alteration in vitamin D metabolism, but to the presence of a residual thyroid secretion. In contrast, hypercalcemia during thyroxine therapy was related to vitamin D supplementation, even though the serum calcium concentration could not be correlated with the circulating concentration of any of the vitamin D metabolites assayed and obvious changes in vitamin D metabolism could not be demonstrated.

Topics: 24,25-Dihydroxyvitamin D 3; 25-Hydroxyvitamin D 2; Alkaline Phosphatase; Calcitriol; Calcium; Congenital Hypothyroidism; Dihydroxycholecalciferols; Ergocalciferols; Humans; Hypercalcemia; Hypothyroidism; Infant, Newborn; Phosphorus; Thyroid Hormones; Thyrotropin; Thyroxine; Time Factors; Vitamin D

1986

Other Studies

1 other study(ies) available for 25-hydroxyvitamin-d-2 and Congenital-Hypothyroidism

Article	Year
Effect of short-term hyperthyroxinemia on vitamin D metabolism in congenital hypothyroidism. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1993, Volume: 25, Issue:7 The circulating concentrations of vitamin D metabolites were measured in nine children (four to ten years of age) with congenital hypothyroidism on L-thyroxine therapy, before and after a short term increase (33%) in dosage. The concentrations of 25-hydroxyvitamin D and 24,25-dihydroxyvitamin D were not altered, but the concentration of 1,25 dihydroxyvitamin D was significantly higher in the serum of the children after three weeks of hyperthyroxinemia. This was associated with an increase in urinary calcium excretion. The increases in serum concentration of 1,25 dihydroxyvitamin D cannot be explained by differences in serum levels of calcium, phosphorus or parathyroid hormone. These findings differ from data obtained in adults. Topics: 25-Hydroxyvitamin D 2; Calcium; Child; Child, Preschool; Congenital Hypothyroidism; Ergocalciferols; Humans; Hypothyroidism; Thyroxine; Vitamin D	1993

Article

Year

Effect of short-term hyperthyroxinemia on vitamin D metabolism in congenital hypothyroidism.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1993, Volume: 25, Issue:7

The circulating concentrations of vitamin D metabolites were measured in nine children (four to ten years of age) with congenital hypothyroidism on L-thyroxine therapy, before and after a short term increase (33%) in dosage. The concentrations of 25-hydroxyvitamin D and 24,25-dihydroxyvitamin D were not altered, but the concentration of 1,25 dihydroxyvitamin D was significantly higher in the serum of the children after three weeks of hyperthyroxinemia. This was associated with an increase in urinary calcium excretion. The increases in serum concentration of 1,25 dihydroxyvitamin D cannot be explained by differences in serum levels of calcium, phosphorus or parathyroid hormone. These findings differ from data obtained in adults.

Topics: 25-Hydroxyvitamin D 2; Calcium; Child; Child, Preschool; Congenital Hypothyroidism; Ergocalciferols; Humans; Hypothyroidism; Thyroxine; Vitamin D

1993