Page last updated: 2024-08-24

25-hydroxycholesterol and Niemann-Pick Disease

25-hydroxycholesterol has been researched along with Niemann-Pick Disease in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's4 (40.00)18.2507
2000's4 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chu, JW; Liu, R; Lu, P; Sharom, FJ1
Crowley, JR; Dudley-Rucker, N; Frolov, A; Ory, DS; Schaffer, JE; Zielinski, SE1
Alrefai, WA; Annaba, F; Dudeja, PK; Dwivedi, A; Gill, RK; Saksena, S; Sarwar, Z; Singla, A1
Dahl, NK; Daunais, MA; Liscum, L1
Asotra, K; Patel, RC; Patel, SC; Patel, YC; Suresh, S1
Patel, RC; Patel, SC; Patel, YC; Suresh, S; Yan, Z1
Ridgway, ND1
Bonnet, J; Louisot, P; Pentchev, PG; Rodriguez-Lafrasse, C; Rousson, R; Vanier, MT1
Byers, DM; Cook, HW; Palmer, FB; Rastogi, SR; Spence, MW1
Faust, JR; Liscum, L1

Reviews

1 review(s) available for 25-hydroxycholesterol and Niemann-Pick Disease

ArticleYear
Interactions between metabolism and intracellular distribution of cholesterol and sphingomyelin.
    Biochimica et biophysica acta, 2000, Apr-12, Volume: 1484, Issue:2-3

    Topics: Animals; Biological Transport; Cell Membrane; Cholesterol; Golgi Apparatus; Humans; Hydroxycholesterols; Intracellular Membranes; Niemann-Pick Diseases; Receptors, Steroid; Sphingomyelin Phosphodiesterase; Sphingomyelins

2000

Other Studies

9 other study(ies) available for 25-hydroxycholesterol and Niemann-Pick Disease

ArticleYear
Characterization of fluorescent sterol binding to purified human NPC1.
    The Journal of biological chemistry, 2009, Jan-16, Volume: 284, Issue:3

    Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Binding Sites; Carrier Proteins; CHO Cells; Cholesterol; Cholic Acids; Cricetinae; Cricetulus; Fluorescent Dyes; Humans; Hydroxycholesterols; Intracellular Signaling Peptides and Proteins; Membrane Glycoproteins; Niemann-Pick C1 Protein; Niemann-Pick Diseases; Protein Binding; Recombinant Proteins

2009
NPC1 and NPC2 regulate cellular cholesterol homeostasis through generation of low density lipoprotein cholesterol-derived oxysterols.
    The Journal of biological chemistry, 2003, Jul-11, Volume: 278, Issue:28

    Topics: Carrier Proteins; Cells, Cultured; Cholesterol; Cholesterol, LDL; DNA-Binding Proteins; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Fibroblasts; Filipin; Gas Chromatography-Mass Spectrometry; Genes, Reporter; Glycoproteins; Humans; Hydroxycholesterols; Intracellular Signaling Peptides and Proteins; Lipoproteins; Lipoproteins, LDL; Liver X Receptors; Luciferases; Membrane Glycoproteins; Microscopy, Fluorescence; Mutation; Niemann-Pick C1 Protein; Niemann-Pick Diseases; Orphan Nuclear Receptors; Oxygen; Phenotype; Receptors, Cytoplasmic and Nuclear; Skin; Sterols; Transfection; Vesicular Transport Proteins

2003
Modulation of human Niemann-Pick C1-like 1 gene expression by sterol: Role of sterol regulatory element binding protein 2.
    American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 292, Issue:1

    Topics: Base Sequence; Caco-2 Cells; Cell Nucleus; Cholesterol; DNA Primers; Gene Expression Regulation; Humans; Hydroxycholesterols; Membrane Proteins; Membrane Transport Proteins; Niemann-Pick Diseases; Plasmids; Promoter Regions, Genetic; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Sterol Regulatory Element Binding Protein 2; Transfection

2007
A second complementation class of cholesterol transport mutants with a variant Niemann-Pick type C phenotype.
    Journal of lipid research, 1994, Volume: 35, Issue:10

    Topics: Animals; Biological Transport; CHO Cells; Cholesterol; Cholesterol, LDL; Cricetinae; Genetic Complementation Test; Genetic Variation; Hydroxycholesterols; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mutation; Niemann-Pick Diseases; Phenotype

1994
25-Hydroxycholesterol induces reorganization of lysosomes in normal but not Niemann-Pick disease type C astrocytes.
    Neuroreport, 1994, Oct-27, Volume: 5, Issue:16

    Topics: Animals; Astrocytes; Hydroxycholesterols; Lysosomes; Mice; Mice, Inbred BALB C; Mice, Neurologic Mutants; Niemann-Pick Diseases; Reference Values

1994
Cellular cholesterol storage in the Niemann-Pick disease type C mouse is associated with increased expression and defective processing of apolipoprotein D.
    Journal of neurochemistry, 1998, Volume: 70, Issue:1

    Topics: Animals; Apolipoproteins; Apolipoproteins D; Astrocytes; Brain; Cells, Cultured; Cholesterol; Gene Expression; Hydroxycholesterols; Mice; Mice, Inbred BALB C; Mice, Neurologic Mutants; Niemann-Pick Diseases; Protein Processing, Post-Translational; RNA, Messenger

1998
Abnormal cholesterol metabolism in imipramine-treated fibroblast cultures. Similarities with Niemann-Pick type C disease.
    Biochimica et biophysica acta, 1990, Apr-02, Volume: 1043, Issue:2

    Topics: Acetates; Cells, Cultured; Cholesterol Esters; Cholesterol, LDL; Down-Regulation; Fibroblasts; Humans; Hydroxycholesterols; Imipramine; Kinetics; Niemann-Pick Diseases

1990
Defective activity of acyl-CoA:cholesterol O-acyltransferase in Niemann-Pick type C and type D fibroblasts.
    The Biochemical journal, 1989, Sep-15, Volume: 262, Issue:3

    Topics: Cells, Cultured; Cholesterol; Fibroblasts; Humans; Hydroxycholesterols; Lipoproteins; Niemann-Pick Diseases; Phospholipids; Sterol O-Acyltransferase; Time Factors

1989
Low density lipoprotein (LDL)-mediated suppression of cholesterol synthesis and LDL uptake is defective in Niemann-Pick type C fibroblasts.
    The Journal of biological chemistry, 1987, Dec-15, Volume: 262, Issue:35

    Topics: Cholesterol; Cholesterol Esters; Fibroblasts; Humans; Hydroxycholesterols; Lipoproteins, LDL; Niemann-Pick Diseases; Time Factors

1987