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25-hydroxycholesterol and Innate Inflammatory Response

25-hydroxycholesterol has been researched along with Innate Inflammatory Response in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.35)18.2507
2000's2 (8.70)29.6817
2010's17 (73.91)24.3611
2020's3 (13.04)2.80

Authors

AuthorsStudies
Han, JH; Jou, I; Lee, JH; Woo, JH1
Andrés-Blasco, I; Canfrán-Duque, A; Fernández-Fuertes, M; Fernández-Hernando, C; Fowler, JW; Giannarelli, C; Gómez-Coronado, D; McDonald, JG; Price, NL; Rotllan, N; Schneider, RJ; Sessa, WC; Suárez, Y; Sun, J; Tellides, G; Thompson, BM; Zhang, X1
Ammit, AJ; Gelissen, IC; He, P; Smith, A1
Cao, Q; Liu, Z; Xiong, Y; Ye, Q; Zhong, Z1
Braga, L; Celsi, F; Crovella, S; Gratton, R; Tricarico, PM1
Cyster, JG; Dang, EV; McDonald, JG; Russell, DW1
Caracciolo, I; Crovella, S; D'Agaro, P; Gratton, R; Tricarico, PM1
Han, Y; Liu, C; Ouyang, W; Wang, S; Xia, J; Xu, F; Zhou, H1
Bandyopadhyay, S; Bose, S; Chang, TH; Colburn, ZT; Gc, JB; Jones, JCR; Natesan, S; Pokharel, SM; Segovia, JA; Shil, NK; Tsai, SY1
Ning, Y; Ren, S1
Kotelevtsev, Y; Lathe, R; Sapronova, A1
Buchmann, J; Engel, T; Fobker, M; Kannenberg, F; Nofer, JR; Rust, S; Schürmann, A; Seedorf, U1
Aderem, A; Askovich, PS; Diercks, AH; Gold, ES; Podolsky, I; Podyminogin, RL; Treuting, PM1
Cyster, JG; Dang, EV; Liang, G; McDonald, JG; Reboldi, A; Russell, DW1
Simon, A1
Bartling, B; Buerke, M; Ebelt, H; Fu, H; Gielen, S; Großmann, J; Hiebl, B; Hofmann, B; Jaschke, C; Koch, S; Larisch, M; Loppnow, H; Müller-Werdan, U; Pilowski, C; Riemann, D; Schlecht, K; Schlitt, A; Seliger, B; Silber, RE; Simm, A; Spieler, F; Unverzagt, S; Werdan, K1
Andreollo, NA; de Faria, EC; Menezes, FH; Moura, FA; Nadruz-Junior, W; Nakandakare, E; Nunes, VS; Petrucci, O; Quintão, EC; Rogerio, F; Scherrer, DZ; Sposito, AC; Virginio, VW1
Chen, JH; Peng, DQ1
Bah, SY; Dickinson, P; Forster, T; Ghazal, P; Kampmann, B1
Cho, HJ; Hwang, I; Im, I; Jang, J; Jin Hur, H; Kang, HC; Kim, DW; Lee, E; Lee, H; Park, S; Pyo Kang, Y; Won Kwon, S; Yang, W; Yu, JW1
Berliner, JA; Choi, J; Cole, AL; Dooley, AN; Fishbein, MC; Gargalovic, P; Hovnanian, T; Kirchgessner, T; Liu, Y; Mouilleseaux, K; Qiao, JH; Shyy, JY; Tulchinsky, D; Vora, DK; Yang, WP; Yeh, M1
Acar, N; Bretillon, L; Bron, A; Buteau, B; Cabaret, S; Creuzot-Garcher, C; Joffre, C; Leclère, L; Lizard, G; Malvitte, L; Martine, L1
Dushkin, MI; Grebenshchikov, AIu; Safina, AF; Shvarts, IaSh; Vereshchagin, EI1

Reviews

5 review(s) available for 25-hydroxycholesterol and Innate Inflammatory Response

ArticleYear
Multiple Roles of 25-Hydroxycholesterol in Lipid Metabolism, Antivirus Process, Inflammatory Response, and Cell Survival.
    Oxidative medicine and cellular longevity, 2020, Volume: 2020

    Topics: Animals; Cell Survival; Humans; Hydroxycholesterols; Inflammation; Lipid Metabolism; Membrane Microdomains; Virus Diseases

2020
Sulfation of 25-hydroxycholesterol regulates lipid metabolism, inflammatory responses, and cell proliferation.
    American journal of physiology. Endocrinology and metabolism, 2014, Jan-15, Volume: 306, Issue:2

    Topics: Animals; Cell Proliferation; Cholesterol Esters; Humans; Hydroxycholesterols; Inflammation; Lipid Metabolism; Liver X Receptors; Orphan Nuclear Receptors; Sterol Regulatory Element Binding Proteins; Sulfatases

2014
Atherosclerosis and Alzheimer--diseases with a common cause? Inflammation, oxysterols, vasculature.
    BMC geriatrics, 2014, Mar-21, Volume: 14

    Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Atherosclerosis; Brain; Humans; Hydroxycholesterols; Inflammation; Inflammation Mediators

2014
Is 25-hydroxycholesterol the interplay of statins and inflammation?
    International journal of cardiology, 2015, Apr-01, Volume: 184

    Topics: Drug Therapy, Combination; Humans; Hydroxycholesterols; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation

2015
Immune oxysterols: Role in mycobacterial infection and inflammation.
    The Journal of steroid biochemistry and molecular biology, 2017, Volume: 169

    Topics: Animals; Anti-Bacterial Agents; Cholesterol; Drug Resistance, Bacterial; Homeostasis; Humans; Hydroxycholesterols; Immune System; Immunity, Innate; Inflammation; Lymphocytes; Macrophages; Mycobacterium; Mycobacterium Infections; Oxysterols; Signal Transduction; Vitamin D

2017

Other Studies

18 other study(ies) available for 25-hydroxycholesterol and Innate Inflammatory Response

ArticleYear
25-Hydroxycholesterol suppress IFN-γ-induced inflammation in microglia by disrupting lipid raft formation and caveolin-mediated signaling endosomes.
    Free radical biology & medicine, 2022, 02-01, Volume: 179

    Topics: Animals; Caveolins; Endosomes; Hydroxycholesterols; Inflammation; Interferon-gamma; Membrane Microdomains; Mice, Inbred C57BL; Microglia; Neuroinflammatory Diseases

2022
Macrophage-Derived 25-Hydroxycholesterol Promotes Vascular Inflammation, Atherogenesis, and Lesion Remodeling.
    Circulation, 2023, 01-31, Volume: 147, Issue:5

    Topics: Animals; Atherosclerosis; Cholesterol; Humans; Hydroxycholesterols; Inflammation; Macrophages; Mice; Mice, Knockout; Plaque, Atherosclerotic

2023
The effect of statins and the synthetic LXR agonist T0901317 on expression of ABCA1 transporter protein in human lung epithelial cell lines in vitro.
    Pharmacological reports : PR, 2019, Volume: 71, Issue:6

    Topics: A549 Cells; ATP Binding Cassette Transporter 1; Cell Line; Cell Line, Tumor; Cholesterol; Epithelial Cells; Humans; Hydrocarbons, Fluorinated; Hydroxycholesterols; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Liver X Receptors; Lung; Sulfonamides; Tumor Necrosis Factor-alpha; Up-Regulation

2019
25-Hydroxycholesterol and inflammation in Lovastatin-deregulated mevalonate pathway.
    The international journal of biochemistry & cell biology, 2017, Volume: 92

    Topics: Apoptosis; Autophagy; Cell Line, Tumor; Humans; Hydroxycholesterols; Inflammation; Interleukin-1beta; Lovastatin; Mevalonic Acid; Protein Prenylation; Signal Transduction

2017
Oxysterol Restraint of Cholesterol Synthesis Prevents AIM2 Inflammasome Activation.
    Cell, 2017, Nov-16, Volume: 171, Issue:5

    Topics: Animals; Cholesterol; DNA-Binding Proteins; DNA, Mitochondrial; Humans; Hydroxycholesterols; Inflammasomes; Inflammation; Interleukin-1beta; Intracellular Signaling Peptides and Proteins; Listeria monocytogenes; Listeriosis; Macrophages; Membrane Proteins; Mice; Mitochondria; Oxysterols

2017
25-hydroxycholesterol reduces inflammation, viral load and cell death in ZIKV-infected U-87 MG glial cell line.
    Inflammopharmacology, 2019, Volume: 27, Issue:3

    Topics: Cell Death; Cell Line, Tumor; Cytokines; Humans; Hydroxycholesterols; Inflammasomes; Inflammation; Interleukin-1beta; Macrophages; Neuroglia; Viral Load; Zika Virus; Zika Virus Infection

2019
25-Hydroxycholesterol protects against acute lung injury via targeting MD-2.
    Journal of cellular and molecular medicine, 2018, Volume: 22, Issue:11

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Humans; Hydroxycholesterols; Inflammation; Lipopolysaccharides; Lung; Lymphocyte Antigen 96; Mice; NF-kappa B; Protective Agents; RAW 264.7 Cells; Signal Transduction; Toll-Like Receptor 4

2018
Integrin activation by the lipid molecule 25-hydroxycholesterol induces a proinflammatory response.
    Nature communications, 2019, 04-01, Volume: 10, Issue:1

    Topics: Animals; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Hydroxycholesterols; Immunity, Innate; Inflammation; Integrin alpha5beta1; Integrin alphaVbeta3; Interleukin-6; Macrophages; Mice; Mice, Knockout; Receptors, Pattern Recognition; Signal Transduction; Tumor Necrosis Factor-alpha

2019
3β,5α,6β-Cholestanetriol and 25-hydroxycholesterol accumulate in ATP-binding cassette transporter G1 (ABCG1)-deficiency.
    Atherosclerosis, 2014, Volume: 235, Issue:1

    Topics: Albumins; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Cell Death; Cholestanols; Female; HeLa Cells; Humans; Hydroxycholesterols; Inflammation; Lipids; Lipoproteins; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Phenotype; Reactive Oxygen Species

2014
25-Hydroxycholesterol acts as an amplifier of inflammatory signaling.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Jul-22, Volume: 111, Issue:29

    Topics: Animals; Disease Models, Animal; Feedback, Physiological; Humans; Hydroxycholesterols; Inflammation; Influenza, Human; Liver X Receptors; Macrophages; Mice; Mice, Inbred C57BL; Orphan Nuclear Receptors; Orthomyxoviridae Infections; Poly I-C; Proto-Oncogene Mas; Signal Transduction; Steroid Hydroxylases; Transcription Factor AP-1; Transcription, Genetic

2014
Inflammation. 25-Hydroxycholesterol suppresses interleukin-1-driven inflammation downstream of type I interferon.
    Science (New York, N.Y.), 2014, Aug-08, Volume: 345, Issue:6197

    Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; Feedback, Physiological; Hydroxycholesterols; Inflammasomes; Inflammation; Interferon Type I; Interleukin-1; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Response Elements; Shock, Septic; Steroid Hydroxylases

2014
Cholesterol metabolism and immunity.
    The New England journal of medicine, 2014, Nov-13, Volume: 371, Issue:20

    Topics: Animals; Hydroxycholesterols; Inflammation; Interferon Type I; Interleukin-1beta; Mevalonate Kinase Deficiency; Mice; Mice, Knockout; Phosphotransferases (Alcohol Group Acceptor); Steroid Hydroxylases

2014
Interleukin-1 potently contributes to 25-hydroxycholesterol-induced synergistic cytokine production in smooth muscle cell-monocyte interactions.
    Atherosclerosis, 2014, Volume: 237, Issue:2

    Topics: Atherosclerosis; Blotting, Western; Cells, Cultured; Chemokine CCL2; Coculture Techniques; Cytokines; Enzyme-Linked Immunosorbent Assay; Humans; Hydroxycholesterols; Immunity, Innate; Inflammation; Interleukin-1beta; Interleukin-6; Monocytes; Myocytes, Smooth Muscle; Polymerase Chain Reaction; Tumor Necrosis Factor-alpha

2014
Arterial tissue and plasma concentration of enzymatic-driven oxysterols are associated with severe peripheral atherosclerotic disease and systemic inflammatory activity.
    Free radical research, 2015, Volume: 49, Issue:2

    Topics: Aged; Aged, 80 and over; Arteries; C-Reactive Protein; Female; Humans; Hydroxycholesterols; Inflammation; Male; Middle Aged; Peripheral Arterial Disease

2015
25-hydroxycholesterol contributes to cerebral inflammation of X-linked adrenoleukodystrophy through activation of the NLRP3 inflammasome.
    Nature communications, 2016, 10-25, Volume: 7

    Topics: Adrenoleukodystrophy; Animals; ATP Binding Cassette Transporter, Subfamily D, Member 1; Corpus Callosum; Fibroblasts; Gene Expression; Hydroxycholesterols; Induced Pluripotent Stem Cells; Inflammasomes; Inflammation; Injections, Intraventricular; Liver X Receptors; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NLR Family, Pyrin Domain-Containing 3 Protein; Oligodendroglia; Primary Cell Culture; Reactive Oxygen Species; Stereotaxic Techniques; Steroid Hydroxylases; White Matter

2016
Role for sterol regulatory element-binding protein in activation of endothelial cells by phospholipid oxidation products.
    Circulation research, 2004, Oct-15, Volume: 95, Issue:8

    Topics: Animals; Aorta; Arteriosclerosis; beta-Cyclodextrins; Cattle; Caveolin 1; Caveolins; CCAAT-Enhancer-Binding Proteins; Cell Compartmentation; Cell Membrane; Cell Nucleus; Cells, Cultured; Cholesterol; DNA-Binding Proteins; Endoplasmic Reticulum; Endothelial Cells; Endothelium, Vascular; Golgi Apparatus; HeLa Cells; Humans; Hydroxycholesterols; Inflammation; Interleukin-8; Intracellular Signaling Peptides and Proteins; Membrane Lipids; Membrane Proteins; Phosphatidylcholines; Phospholipid Ethers; Recombinant Fusion Proteins; STAT3 Transcription Factor; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Trans-Activators; Transcription Factors; Transcription, Genetic; Transfection

2004
Oxysterols induced inflammation and oxidation in primary porcine retinal pigment epithelial cells.
    Current eye research, 2007, Volume: 32, Issue:3

    Topics: Animals; Chromatography, Gas; Enzyme-Linked Immunosorbent Assay; Fluoresceins; Fluorescent Dyes; Hydroxycholesterols; Inflammation; Interleukin-8; Ketocholesterols; Mitochondria; Oxidative Stress; Pigment Epithelium of Eye; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine

2007
[Effects of hydroxysterols on expression of inflammatory cytokine genes and their level in macrophages tolerant to endotoxin].
    Biulleten' eksperimental'noi biologii i meditsiny, 1999, Volume: 127, Issue:1

    Topics: Animals; Cells, Cultured; Gene Expression; Hydroxycholesterols; Inflammation; Interleukin-1; Ketocholesterols; Lipopolysaccharides; Macrophages, Peritoneal; Male; Rats; Rats, Wistar; RNA, Messenger; Tumor Necrosis Factor-alpha

1999