Page last updated: 2024-08-24

25-hydroxycholesterol and Disease Models, Animal

25-hydroxycholesterol has been researched along with Disease Models, Animal in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (16.67)18.2507
2000's2 (11.11)29.6817
2010's8 (44.44)24.3611
2020's5 (27.78)2.80

Authors

AuthorsStudies
Cai, Y; Jiang, S; Jiao, F; Lan, Q; Lu, L; Wang, C; Wang, L; Xia, S; Zhang, Y; Zhou, J1
Bensinger, SJ; Bui, VL; Chi, X; Daly, AE; Damoiseaux, R; Feng, AC; Ferrari, A; He, C; Hsieh, WY; Kronenberger, EB; Lee, MS; Mkrtchyan, JJ; Scumpia, PO; Smale, ST; Tarling, EJ; Tontonoz, P; Williams, KJ; Xiao, X; York, AG; Zhou, QD1
Chen, Q; Cheng, G; Deng, YQ; Gold, S; He, J; Li, J; Li, L; Li, X; Li, XF; Qin, CF; Yang, H; Zhang, C; Zhao, H; Zhou, C; Zu, S1
Giniatullin, AR; Kuznetsova, EA; Mukhutdinova, KA; Petrov, AM; Zakyrjanova, GF1
Cao, Q; Liu, Z; Luo, J; Xiong, Y; Ye, Q1
Aliyari, R; Au, C; Buth, JE; Cheng, G; Dai, X; Deng, YQ; Dong, HL; Du, P; Fan, J; Gong, D; Hong, S; Huang, XY; Li, C; Li, L; Li, XF; Liu, P; Liu, Y; Lu, N; Ma, F; Novitch, BG; Qin, CF; Qin, FX; Sun, R; Tian, M; Vishlaghi, N; Wang, S; Watanabe, M; Xu, Z; Ye, Q; Zhang, B; Zhang, NN; Zhao, H1
Han, Y; Liu, C; Ouyang, W; Wang, S; Xia, J; Xu, F; Zhou, H1
Alhouayek, M; Bottemanne, P; Buisseret, B; Guillemot-Legris, O; Lemaire, J; Muccioli, GG; Mutemberezi, V; Palmieri, V; Paquot, A; Rahier, JF1
Daszynski, DM; Kador, PF; Lou, MF; Phadte, AS; Santhoshkumar, P; Sharma, KK; Zhong, HA1
Aderem, A; Askovich, PS; Diercks, AH; Gold, ES; Podolsky, I; Podyminogin, RL; Treuting, PM1
Kakiyama, G; Kim, JK; Min, HK; Ning, Y; Pandak, WM; Ren, S; Rodriguez-Agudo, D1
Andley, UP; DeVree, BT; Dunyak, BM; Gestwicki, JE; Goldman, JW; Klevit, RE; Makley, LN; McGlasson, BN; McMenimen, KA; McQuade, TJ; Rajagopal, P; Sunahara, R; Thompson, AD1
Alejandre, MJ; Iglesias, J; Linares, A; Palomino-Morales, R; Perales, S; Torres, C1
Dijkstra, MH; Gurzeler, E; Heinonen, SE; Jauhiainen, S; Kivelä, AM; Levonen, AL; Ylä-Herttuala, S1
Collins, JL; Elias, PM; Feingold, KR; Fluhr, JW; Fowler, AJ; Kao, J; Mangelsdorf, DJ; Rhein, L; Schmuth, M; Sheu, MY; Willson, TM1
Godin, DV; Kitts, DD; Yuan, YV1
Boissonneault, GA; Hennig, B; Ouyang, CM1
Black, BL; Guyton, JR; Seidel, CL1

Other Studies

18 other study(ies) available for 25-hydroxycholesterol and Disease Models, Animal

ArticleYear
25-Hydroxycholesterol-Conjugated EK1 Peptide with Potent and Broad-Spectrum Inhibitory Activity against SARS-CoV-2, Its Variants of Concern, and Other Human Coronaviruses.
    International journal of molecular sciences, 2021, Nov-01, Volume: 22, Issue:21

    Topics: Amino Acid Sequence; Animals; Antiviral Agents; Body Weight; Coronavirus 229E, Human; Coronavirus Infections; Coronavirus OC43, Human; COVID-19; COVID-19 Drug Treatment; Disease Models, Animal; Drug Synergism; Humans; Hydroxycholesterols; Lipopeptides; Mice; Mice, Inbred BALB C; Polyethylene Glycols; SARS-CoV-2; Survival Rate; Virus Internalization

2021
Interferon-mediated reprogramming of membrane cholesterol to evade bacterial toxins.
    Nature immunology, 2020, Volume: 21, Issue:7

    Topics: Animals; Bacteria; Bacterial Infections; Bacterial Proteins; Bacterial Toxins; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; Disease Models, Animal; Disease Susceptibility; Female; Host Microbial Interactions; Humans; Hydroxycholesterols; Interferons; Intravital Microscopy; Male; Mice; Mice, Transgenic; Phagocytes; Primary Cell Culture; Steroid Hydroxylases; Streptolysins

2020
25-Hydroxycholesterol is a potent SARS-CoV-2 inhibitor.
    Cell research, 2020, Volume: 30, Issue:11

    Topics: Aged; Angiotensin-Converting Enzyme 2; Animals; Betacoronavirus; Chlorocebus aethiops; Coronavirus Infections; COVID-19; Disease Models, Animal; Fatal Outcome; Female; Humans; Hydroxycholesterols; Mice; Mice, Inbred BALB C; Mice, Transgenic; Pandemics; Peptidyl-Dipeptidase A; Pneumonia, Viral; Reverse Transcriptase Polymerase Chain Reaction; SARS-CoV-2; Vero Cells; Virus Replication

2020
Early differences in membrane properties at the neuromuscular junctions of ALS model mice: Effects of 25-hydroxycholesterol.
    Life sciences, 2021, May-15, Volume: 273

    Topics: Acetylcholine; Amyotrophic Lateral Sclerosis; Animals; Ceramides; Cholesterol; Disease Models, Animal; Female; Hydroxycholesterols; Male; Membrane Microdomains; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; Neuromuscular Junction; Superoxide Dismutase-1; Synaptic Transmission

2021
25-Hydroxycholesterol mitigates hepatic ischemia reperfusion injury via mediating mitophagy.
    International immunopharmacology, 2021, Volume: 96

    Topics: Adenine; Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Disease Models, Animal; Hydroxycholesterols; Liver Diseases; Male; Mitophagy; NLR Family, Pyrin Domain-Containing 3 Protein; Protective Agents; Protein Kinases; Rats, Sprague-Dawley; Reperfusion Injury; Ubiquitin-Protein Ligases

2021
25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model.
    Immunity, 2017, 03-21, Volume: 46, Issue:3

    Topics: Animals; Antiviral Agents; Brain; Disease Models, Animal; Fluorescent Antibody Technique; Humans; Hydroxycholesterols; Macaca mulatta; Mice; Microcephaly; Microscopy, Confocal; Virus Internalization; Zika Virus; Zika Virus Infection

2017
25-Hydroxycholesterol protects against acute lung injury via targeting MD-2.
    Journal of cellular and molecular medicine, 2018, Volume: 22, Issue:11

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Humans; Hydroxycholesterols; Inflammation; Lipopolysaccharides; Lung; Lymphocyte Antigen 96; Mice; NF-kappa B; Protective Agents; RAW 264.7 Cells; Signal Transduction; Toll-Like Receptor 4

2018
Colitis Alters Oxysterol Metabolism and is Affected by 4β-Hydroxycholesterol Administration.
    Journal of Crohn's & colitis, 2019, Feb-01, Volume: 13, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Colitis; Colitis, Ulcerative; Colon; Crohn Disease; Disease Models, Animal; Humans; Hydroxycholesterols; Liver; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Oxysterols; Peroxidase; Real-Time Polymerase Chain Reaction; Transcriptome

2019
Failure of Oxysterols Such as Lanosterol to Restore Lens Clarity from Cataracts.
    Scientific reports, 2019, 06-11, Volume: 9, Issue:1

    Topics: alpha-Crystallin B Chain; Animals; Cataract; Crystallins; Disease Models, Animal; Humans; Hydroxycholesterols; Lanosterol; Lens, Crystalline; Molecular Chaperones; Oxysterols; Rats

2019
25-Hydroxycholesterol acts as an amplifier of inflammatory signaling.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Jul-22, Volume: 111, Issue:29

    Topics: Animals; Disease Models, Animal; Feedback, Physiological; Humans; Hydroxycholesterols; Inflammation; Influenza, Human; Liver X Receptors; Macrophages; Mice; Mice, Inbred C57BL; Orphan Nuclear Receptors; Orthomyxoviridae Infections; Poly I-C; Proto-Oncogene Mas; Signal Transduction; Steroid Hydroxylases; Transcription Factor AP-1; Transcription, Genetic

2014
Identification of novel regulatory cholesterol metabolite, 5-cholesten, 3β,25-diol, disulfate.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: Acetyl-CoA Carboxylase; Adenoviridae; Animals; Cells, Cultured; Cholesterol; Cholesterol Esters; Disease Models, Animal; Fatty Acid Synthases; Female; Hep G2 Cells; Hepatocytes; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Lipid Metabolism; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Rats; Signal Transduction; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Viral Proteins

2014
Pharmacological chaperone for α-crystallin partially restores transparency in cataract models.
    Science (New York, N.Y.), 2015, Nov-06, Volume: 350, Issue:6261

    Topics: alpha-Crystallin A Chain; alpha-Crystallin B Chain; Amyloid; Animals; Calorimetry, Differential Scanning; Cataract; Disease Models, Animal; Gene Knock-In Techniques; Humans; Hydroxycholesterols; Mice; Protein Conformation; Protein Stability

2015
Effect of oxysterol-induced apoptosis of vascular smooth muscle cells on experimental hypercholesterolemia.
    Journal of biomedicine & biotechnology, 2009, Volume: 2009

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Chickens; Data Interpretation, Statistical; Diet, Atherogenic; Disease Models, Animal; Gene Expression; Hydroxycholesterols; Hypercholesterolemia; Male; Myocytes, Smooth Muscle; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger

2009
Regulation of endothelial lipase and systemic HDL cholesterol levels by SREBPs and VEGF-A.
    Atherosclerosis, 2012, Volume: 225, Issue:2

    Topics: Adenoviridae; Animals; Apolipoprotein B-100; Atherosclerosis; Binding Sites; Blotting, Western; Cells, Cultured; Cholesterol, HDL; Chromatin Immunoprecipitation; Disease Models, Animal; Endothelial Cells; Gene Expression Regulation, Enzymologic; Gene Transfer Techniques; Genetic Vectors; Human Umbilical Vein Endothelial Cells; Humans; Hydroxycholesterols; Lipase; Mice; Mice, Knockout; Polymerase Chain Reaction; Promoter Regions, Genetic; Receptors, LDL; RNA Interference; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Time Factors; Transfection; Vascular Endothelial Growth Factor A

2012
Liver X receptor activators display anti-inflammatory activity in irritant and allergic contact dermatitis models: liver-X-receptor-specific inhibition of inflammation and primary cytokine production.
    The Journal of investigative dermatology, 2003, Volume: 120, Issue:2

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Carcinogens; Dermatitis, Irritant; Disease Models, Animal; DNA-Binding Proteins; Epidermis; Female; Hydroxycholesterols; Interleukin-1; Liver X Receptors; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Orphan Nuclear Receptors; Oxazolone; Receptors, Cytoplasmic and Nuclear; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2003
Interactive effects of increased intake of saturated fat and cholesterol on atherosclerosis in the Japanese quail (Coturnix japonica).
    The British journal of nutrition, 1998, Volume: 80, Issue:1

    Topics: Analysis of Variance; Animals; Aorta; Arteriosclerosis; Bird Diseases; Cholestanols; Cholesterol; Cholesterol, Dietary; Coturnix; Dietary Fats; Disease Models, Animal; Energy Intake; Hydroxycholesterols; Hypolipidemic Agents; Ketocholesterols; Lipids; Lipoproteins; Male; Regression Analysis

1998
Oxysterols, cholesterol biosynthesis, and vascular endothelial cell monolayer barrier function.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1991, Volume: 196, Issue:3

    Topics: Animals; Biological Transport; Cell Membrane Permeability; Cholestanes; Cholestanols; Cholesterol; Dehydrocholesterols; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium; Hydroxycholesterols; Hypolipidemic Agents; In Vitro Techniques; Ketocholesterols; Lovastatin; Serum Albumin; Swine; Time Factors

1991
Focal toxicity of oxysterols in vascular smooth muscle cell culture. A model of the atherosclerotic core region.
    The American journal of pathology, 1990, Volume: 137, Issue:2

    Topics: Animals; Aorta; Arteriosclerosis; Cell Movement; Cell Survival; Cells, Cultured; Chemotaxis; Cholestanols; Disease Models, Animal; DNA; Dogs; Hydroxycholesterols; Hypolipidemic Agents; Microscopy, Phase-Contrast; Muscle, Smooth, Vascular

1990