25-26-dihydroxycholecalciferol and Osteosarcoma

25-26-dihydroxycholecalciferol has been researched along with Osteosarcoma* in 1 studies

Other Studies

1 other study(ies) available for 25-26-dihydroxycholecalciferol and Osteosarcoma

ArticleYear
Cytotoxic effects of 24R,25-dihydroxycholecalciferol on the proliferation of various tumor cell lines in vitro and its antitumor effects in vivo.
    Oncology, 1988, Volume: 45, Issue:3

    24R,25(OH)2D3, one of the endogenous active metabolites of vitamin D3, showed suppressive effects on the proliferation of various tumor cells in vitro, and showed a suppressive effect on the growth of human osteosarcoma transplanted in nude mice. 24R,25(OH)2D3 increased bone strength lowered by the tumor burden which causes abnormal calcium metabolism and results in hypercalcemia.

    Topics: Animals; Antineoplastic Agents; Bone and Bones; Carcinoma; Cell Division; Dihydroxycholecalciferols; Humans; Hypercalcemia; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Neoplasm Transplantation; Osteosarcoma; Rats; Stress, Mechanical; Transplantation, Heterologous; Tumor Cells, Cultured

1988