24-hydroxycholesterol has been researched along with Acute Confusional Senile Dementia in 49 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 27 (55.10) | 29.6817 |
| 2010's | 21 (42.86) | 24.3611 |
| 2020's | 1 (2.04) | 2.80 |
| Authors | Studies |
|---|---|
| Bajaj, JS; Barbier, O; Bosoi, CR; Calon, F; Fanet, H; Leclerc, M; Lippman, HR; Marette, A; Mitchell, PL; Tournissac, M; Tremblay, C; Trottier, J; Vandal, M; Verreault, M; Virgili, J | 1 |
| Dong, SY; Li, HY; Li, L; Liu, YH; Peng, ZY; Wang, YJ; Zeng, F; Zhou, HD | 1 |
| Catanozi, S; Cazita, PM; Nakandakare, ER; Nunes, VS; Quintão, ECR | 1 |
| Gamba, P; Gargiulo, S; Giannelli, S; Guglielmotto, M; Leonarduzzi, G; Staurenghi, E; Tabaton, M; Tamagno, E; Testa, G | 1 |
| Goikolea, J; Loera-Valencia, R; Maioli, S; Merino-Serrais, P; Parrado-Fernandez, C | 1 |
| Andreazza, AC; Black, SE; Gallagher, D; Herrmann, N; Kiss, A; Lanctôt, KL; Ruthirakuhan, M; Verhoeff, NPLG | 1 |
| Caccia, C; Leoni, V | 1 |
| Björkhem, I; Blennow, K; Hansson, O; Kivipelto, M; Leoni, V; Lövgren-Sandblom, A; Minthon, L; Solomon, A; Wahlund, LO | 1 |
| Eckert, GP; Li, L; Müller, WE; Wood, WG | 1 |
| Biasi, F; Gamba, P; Gargiulo, S; Giaccone, G; Guglielmotto, M; Iuliano, L; Leonarduzzi, G; Mauro, A; Monteleone, D; Poli, G; Tamagno, E; Testa, G; Zerbinati, C | 1 |
| Hammami, M; Lizard, G; Moreau, T; Zarrouk, A | 1 |
| Liu, Q; Zhang, J | 1 |
| Audrain, M; Auzeil, N; Ayciriex, S; Bièche, I; Blum, D; Braudeau, J; Buée, L; Burlot, MA; Caillierez, R; Cartier, N; Dauphinot, L; Djelti, F; Dutar, P; Fernandez-Gomez, FJ; Gautier, B; Korte, M; Laprévote, O; Michaelsen-Preusse, K; Potier, B; Potier, MC; Varin, J | 1 |
| Kuo, SH; Liu, N; Liu, XG; Song, QY; Wang, HL; Wang, MW; Wang, YY | 1 |
| An, Y; Feng, L; Liu, Q; Lu, Y; Wang, C; Xiao, R; Yu, H | 1 |
| Hentschel, F; Heun, R; Jessen, F; Kelemen, P; Kölsch, H; Lütjohann, D; Maier, W; Popp, J; Schmitz, S | 1 |
| Andreasen, N; Besga, A; Björkhem, I; Julin, P; Kivipelto, M; Leoni, V; Oksengård, AR; Soininen, H; Solomon, A; Svensson, L; Wahlund, LO; Winblad, B | 1 |
| Ahouansou, O; Aubourg, P; Benraiss, A; Bougnères, P; Cartier, N; De Deyn, PP; Delacourte, A; Hudry, E; Kulik, W; Stet, FS; Van Dam, D | 1 |
| Kaul, D; Raina, A | 1 |
| Biasi, F; Gamba, P; Gargiulo, S; Guglielmotto, M; Leonarduzzi, G; Mauro, A; Poli, G; Sottero, B; Tamagno, E; Testa, G; Viña, J | 1 |
| Jeitner, TM; Reiss, AB; Voloshyna, I | 1 |
| Bonetti, F; Bosi, C; Cortese, C; Dalla Nora, E; Donnorso, MP; Mozzi, AF; Passaro, A; Zuliani, G; Zurlo, A | 1 |
| Becker, JT; Evans, RW; Hughes, TM; Kuller, LH; Lopez, OL; Rosano, C; Sutton-Tyrrell, K | 1 |
| Jessen, F; Kölsch, H; Kornhuber, J; Lewczuk, P; Lütjohann, D; Maier, W; Meichsner, S; Popp, J | 1 |
| Heun, R; Jessen, F; Kölsch, H; Ludwig, M; Lütjohann, D; Maier, W; Ptok, U; Rao, ML; Schulte, A; von Bergmann, K | 1 |
| Benussi, L; Binetti, G; Braak, H; Brühl, A; Ghebremedhin, E; Hegi, T; Hock, C; Iakovidou, V; Lütjohann, D; Maddalena, A; Nicosia, F; Nitsch, RM; Papassotiropoulos, A; Pasch, T; Schmid, S; Streffer, JR; Thal, D; Träxler, M; Tsolaki, M | 1 |
| Heun, R; Kölsch, H; Lütjohann, D; von Bergmann, K | 1 |
| Lipton, AM; Lutjohann, D; Moore, C; Svetlik, D; Vega, GL; Von Bergmann, K; Weiner, MF | 1 |
| Blom, HJ; Bosma, H; Bosmans, E; De Bruijn, C; de Vente, J; Delanghe, J; Lütjohann, D; Maes, M; Rieckmann, P; Steinbusch, HW; Teunissen, CE; van Boxtel, MP; Verbeek, MM; Verhey, F; von Bergmann, K; Vreeling, F; Wauters, A | 1 |
| Bayer, T; Björkhem, I; Bogdanovic, N; Bretillon, L; Diczfalusy, U; Heverin, M; Lütjohann, D; Pikuleva, I; Winblad, B | 1 |
| Lütjohann, D; von Bergmann, K | 1 |
| Chan, ES; de Leon, MJ; Ghiso, J; Rahman, MM; Reiss, AB; Siller, KA | 1 |
| Heun, R; Kölsch, H; Lütjohann, D; Maier, W; Sauder, S; Schulz, A; von Bergmann, K | 1 |
| Lütjohann, D; Mijatovic, V; Netelenbos, JC; Pinsdorf, U; van der Mooren, MJ; Vogelvang, TE; von Bergmann, K | 1 |
| Heun, R; Jessen, F; Kölsch, H; Lütjohann, D; Maier, W; Urbach, H; von Bergmann, K | 1 |
| Heun, R; Kölsch, H; Lutjohan, D; Moore, C; Nguyen, A; Vega, GL; von Bergmann, K; Weiner, M | 1 |
| Brunner, F; Hock, C; Lütjohann, D; Molyva, D; Nitsch, RM; Papassotiropoulos, A; Tsolaki, M; Wollmer, MA | 1 |
| Heun, R; Jessen, F; Kölsch, H; Lütjohann, D; Maier, W; Schmitz, S; Urbach, H; Von Bergmann, K | 1 |
| Lukiw, WJ | 1 |
| Björkhem, I; Diczfalusy, U; Heverin, M; Leoni, V; Meaney, S | 1 |
| Björkhem, I | 1 |
| Björkhem, I; Kivipelto, M; Leoni, V; Shafaati, M; Solomon, A | 1 |
| Vega, GL; Weiner, MF | 1 |
| Bagli, M; Björkhem, I; Heun, R; Jessen, F; Locatelli, S; Lütjohann, D; Oehring, RD; Papassotiropoulos, A; Rao, ML; Schlegel, U; von Bergmann, K | 1 |
| Bagli, M; Björkhem, I; Heun, R; Jessen, F; Locatelli, S; Lütjohann, D; Maier, W; Papassotiropoulos, A; Rao, ML; von Bergmann, K | 1 |
| Björkhem, I; Bretillon, L; Crisby, M; Diczfalusy, U; Groth, CG; Hillert, J; Lütjohann, D; Minthon, L; Sidén, A; Wahlund, LO | 1 |
| Björkhem, I; Bogdanovic, N; Bretillon, L; Diczfalusy, U; Lannfelt, L; Lund, EG; Russell, DW; Winblad, B | 1 |
| Beisiegel, U; Locatelli, S; Lütjohann, D; Otto, C; Schmidt, HH; von Bergmann, K | 1 |
| Bardenheuer, H; Beyreuther, K; Hartmann, T; Lütjohann, D; Pantel, J; Schönknecht, P; Schröder, J; von Bergmann, K | 1 |
12 review(s) available for 24-hydroxycholesterol and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Alterations in cholesterol metabolism as a risk factor for developing Alzheimer's disease: Potential novel targets for treatment.
Topics: Alzheimer Disease; Animals; Anticholesteremic Agents; Brain; Cholestanetriol 26-Monooxygenase; Cholesterol; Cholesterol 24-Hydroxylase; Humans; Hydroxycholesterols; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Risk Factors | 2019 |
Potential diagnostic applications of side chain oxysterols analysis in plasma and cerebrospinal fluid.
Topics: Alzheimer Disease; Animals; Biomarkers; Brain; Cholesterol; Humans; Hydroxycholesterols; Neurodegenerative Diseases; Oxidation-Reduction | 2013 |
Cholesterol as a causative factor in Alzheimer's disease: a debatable hypothesis.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Apolipoproteins E; Astrocytes; Cell Membrane; Cells, Cultured; Cholesterol; Cholesterol, Dietary; Disease Models, Animal; Humans; Hydroxycholesterols; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Mice; Models, Biological; Neurons; Polyisoprenyl Phosphates; Rabbits; Sesquiterpenes | 2014 |
Cholesterol metabolism and homeostasis in the brain.
Topics: Alzheimer Disease; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Brain; Cholesterol; Gene Expression Regulation; Homeostasis; Humans; Huntington Disease; Hydroxycholesterols; Lipid Metabolism; Neurons; Parkinson Disease; Receptors, Lipoprotein | 2015 |
Cholesterol, 24-Hydroxycholesterol, and 27-Hydroxycholesterol as Surrogate Biomarkers in Cerebrospinal Fluid in Mild Cognitive Impairment and Alzheimer's Disease: A Meta-Analysis.
Topics: Alzheimer Disease; Cholesterol; Cognitive Dysfunction; Databases, Bibliographic; Humans; Hydroxycholesterols | 2016 |
Oxysterol derivatives of cholesterol in neurodegenerative disorders.
Topics: Alzheimer Disease; Animals; Blood-Brain Barrier; Cholesterol; Humans; Hydroxycholesterols; Multiple Sclerosis; Neurodegenerative Diseases; Paraplegia; Structure-Activity Relationship | 2011 |
The role of 24S-hydroxycholesterol in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Humans; Hydroxycholesterols | 2003 |
Cholesterol in neurologic disorders of the elderly: stroke and Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Cholesterol; Humans; Hydroxycholesterols; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracranial Arteriosclerosis; Steroid Hydroxylases; Stroke | 2004 |
Cholesterol and 24S-hydroxycholesterol trafficking in Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Brain; Cholesterol; Humans; Hydroxycholesterols | 2006 |
Oxysterols and Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Blood-Brain Barrier; Brain; Humans; Hydroxycholesterols; Hypercholesterolemia | 2006 |
Crossing the barrier: oxysterols as cholesterol transporters and metabolic modulators in the brain.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Biological Transport; Blood-Brain Barrier; Brain; Brain Diseases; Cholesterol; Cholesterol 24-Hydroxylase; Homeostasis; Humans; Hydroxycholesterols; Infant; Rats; Steroid Hydroxylases | 2006 |
Plasma 24S hydroxycholesterol response to statins in Alzheimer's disease patients: effects of gender, CYP46, and ApoE polymorphisms.
Topics: Alzheimer Disease; Apolipoproteins E; Brain; Cholesterol; Cholesterol 24-Hydroxylase; Female; Humans; Hydroxycholesterols; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Polymorphism, Genetic; Sex Characteristics; Steroid Hydroxylases | 2007 |
4 trial(s) available for 24-hydroxycholesterol and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Reduction in levels of 24S-hydroxycholesterol by statin treatment in patients with Alzheimer disease.
Topics: Aged; Alzheimer Disease; Brain; Cholesterol 24-Hydroxylase; Female; Humans; Hydroxycholesterols; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Middle Aged; Niacin; Pravastatin; Simvastatin; Steroid Hydroxylases; Treatment Outcome | 2003 |
Combination of serum markers related to several mechanisms in Alzheimer's disease.
Topics: Adult; Aged; Aged, 80 and over; Aging; alpha 1-Antichymotrypsin; Alzheimer Disease; Analysis of Variance; Biomarkers; Chi-Square Distribution; Cholesterol; Cysteine; Female; Follow-Up Studies; Humans; Hydroxycholesterols; Interleukin-6; Logistic Models; Male; Middle Aged; Neurodegenerative Diseases; Parkinson Disease; Reference Values; Serum; Sterols | 2003 |
Effect of raloxifene and hormone therapy on serum markers of brain and whole-body cholesterol metabolism in postmenopausal women.
Topics: Alzheimer Disease; Biomarkers; Brain; Cholesterol; Double-Blind Method; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Humans; Hydroxycholesterols; Medroxyprogesterone Acetate; Middle Aged; Postmenopause; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Treatment Outcome | 2005 |
Reduction of plasma 24S-hydroxycholesterol (cerebrosterol) levels using high-dosage simvastatin in patients with hypercholesterolemia: evidence that simvastatin affects cholesterol metabolism in the human brain.
Topics: Administration, Oral; Adult; Aged; Alzheimer Disease; Anticholesteremic Agents; Brain; Cholesterol; Female; Humans; Hydroxycholesterols; Hypercholesterolemia; Male; Middle Aged; Prospective Studies; Simvastatin | 2002 |
33 other study(ies) available for 24-hydroxycholesterol and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
High-Fat Diet Modulates Hepatic Amyloid β and Cerebrosterol Metabolism in the Triple Transgenic Mouse Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Brain-Gut Axis; Diet, High-Fat; Disease Models, Animal; Hydroxycholesterols; Lipogenesis; Liver; Mice; Mice, Obese; Mice, Transgenic | 2021 |
CYP46A1 and the APOEε4 Allele Polymorphisms Correlate with the Risk of Alzheimer's Disease.
Topics: Aged; Alleles; Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Case-Control Studies; Cholesterol 24-Hydroxylase; Demography; Female; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Hydroxycholesterols; Male; Polymorphism, Single Nucleotide; Risk Factors; Severity of Illness Index | 2018 |
Decreased content, rate of synthesis and export of cholesterol in the brain of apoE knockout mice.
Topics: Alzheimer Disease; Animals; Apolipoproteins E; Biological Transport; Brain; Cholesterol; Hydroxycholesterols; Mice; Mice, Knockout; Phytosterols | 2018 |
A silver lining for 24-hydroxycholesterol in Alzheimer's disease: The involvement of the neuroprotective enzyme sirtuin 1.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Disease Models, Animal; Humans; Hydroxycholesterols; Ketocholesterols; Mice; Mice, Transgenic; Neurons; Neuroprotective Agents; Oxidation-Reduction; Sirtuin 1; tau Proteins | 2018 |
24S-Hydroxycholesterol Is Associated with Agitation Severity in Patients with Moderate-to-Severe Alzheimer's Disease: Analyses from a Clinical Trial with Nabilone.
Topics: Aged, 80 and over; Alzheimer Disease; Anti-Anxiety Agents; Cross-Sectional Studies; Dronabinol; Female; Humans; Hydroxycholesterols; Longitudinal Studies; Male; Psychomotor Agitation; Treatment Outcome | 2019 |
Diagnostic power of 24S-hydroxycholesterol in cerebrospinal fluid: candidate marker of brain health.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Brain; Cognitive Dysfunction; Female; Humans; Hydroxycholesterols; Male; Middle Aged | 2013 |
Up-regulation of β-amyloidogenesis in neuron-like human cells by both 24- and 27-hydroxycholesterol: protective effect of N-acetyl-cysteine.
Topics: Acetylcysteine; Alzheimer Disease; Amyloid beta-Peptides; Cell Line, Tumor; Disease Progression; Humans; Hydroxycholesterols; Neurons; Oxidative Stress; Up-Regulation | 2014 |
Accumulation of 24S-hydroxycholesterol in neuronal SK-N-BE cells treated with hexacosanoic acid (C26:0): argument in favor of 24S-hydroxycholesterol as a potential biomarker of neurolipotoxicity.
Topics: Alzheimer Disease; Animals; Biomarkers; Brain; Cell Line; Cholesterol; Fatty Acids; Humans; Hydroxycholesterols; Lipids; Neurons; Neurotoxicity Syndromes | 2015 |
Cholesterol 24-hydroxylase defect is implicated in memory impairments associated with Alzheimer-like Tau pathology.
Topics: Alzheimer Disease; Animals; Cholesterol 24-Hydroxylase; Disease Models, Animal; Gliosis; Hippocampus; Humans; Hydroxycholesterols; Memory Disorders; Mice; Mice, Transgenic; Phosphorylation; Steroid Hydroxylases; tau Proteins; Tauopathies | 2015 |
Relationship between oxysterols and mild cognitive impairment in the elderly: a case-control study.
Topics: Aged; Alzheimer Disease; Chromatography, High Pressure Liquid; Cognitive Dysfunction; Female; Humans; Hydroxycholesterols; Male; Mass Spectrometry; Middle Aged | 2016 |
CYP46A1 variants influence Alzheimer's disease risk and brain cholesterol metabolism.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Brain; Cholesterol; Cholesterol 24-Hydroxylase; Female; Genetic Predisposition to Disease; Genetic Variation; Haplotypes; Humans; Hydroxycholesterols; Male; Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Steroid Hydroxylases | 2009 |
Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease.
Topics: Age Factors; Aged; Alzheimer Disease; Apolipoproteins E; Brain; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cognition Disorders; Female; Genotype; Humans; Hydroxycholesterols; Lanosterol; Male; Middle Aged; Organ Size; Sex Factors | 2009 |
Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid; Animals; Blotting, Western; Cell Line; Cholesterol 24-Hydroxylase; Dependovirus; Enzyme-Linked Immunosorbent Assay; Genetic Therapy; Humans; Hydroxycholesterols; Immunohistochemistry; Mice; Mice, Transgenic; Reverse Transcriptase Polymerase Chain Reaction; Steroid Hydroxylases | 2010 |
LXR-α genomics programmes neuronal death observed in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Apoptosis; Apoptosis Regulatory Proteins; Cloning, Molecular; Epigenomics; Gene Expression Regulation; Humans; Hydroxycholesterols; Liver X Receptors; Neuroblastoma; Neurons; Orphan Nuclear Receptors; Reactive Oxygen Species; Recombinant Proteins; Repressor Proteins; Tumor Cells, Cultured; Withanolides | 2010 |
Interaction between 24-hydroxycholesterol, oxidative stress, and amyloid-β in amplifying neuronal damage in Alzheimer's disease: three partners in crime.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Apoptosis; Brain; CD36 Antigens; Cell Line, Tumor; Genistein; Glutathione; Glutathione Disulfide; Humans; Hydroxycholesterols; Integrin beta Chains; NADPH Oxidases; Necrosis; Neurons; Oxidation-Reduction; Oxidative Stress; Peptide Fragments; Plaque, Amyloid; Quercetin; Reactive Oxygen Species; Up-Regulation | 2011 |
Plasma 24S-hydroxycholesterol levels in elderly subjects with late onset Alzheimer's disease or vascular dementia: a case-control study.
Topics: Aged; Alzheimer Disease; Atrophy; Biomarkers; Brain; C-Reactive Protein; Case-Control Studies; Cholesterol; Cognitive Dysfunction; Dementia, Vascular; Female; Genotype; Humans; Hydroxycholesterols; Male; Polymorphism, Single Nucleotide; PPAR gamma; Radiography | 2011 |
Markers of cholesterol metabolism in the brain show stronger associations with cerebrovascular disease than Alzheimer's disease.
Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Apolipoprotein E4; Brain; Cerebrovascular Disorders; Cognition Disorders; Cohort Studies; Female; Humans; Hydroxycholesterols; Magnetic Resonance Imaging; Male; Retrospective Studies | 2012 |
Cholesterol metabolism is associated with soluble amyloid precursor protein production in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Amyloid beta-Protein Precursor; Biomarkers; Cholesterol; Female; Humans; Hydroxycholesterols; Male; Middle Aged; Up-Regulation | 2012 |
Polymorphism in the cholesterol 24S-hydroxylase gene is associated with Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Cell Death; Cholesterol; Cholesterol 24-Hydroxylase; Female; Humans; Hydroxycholesterols; Male; Middle Aged; Neurons; Polymorphism, Genetic; Steroid Hydroxylases | 2002 |
Increased brain beta-amyloid load, phosphorylated tau, and risk of Alzheimer disease associated with an intronic CYP46 polymorphism.
Topics: Age of Onset; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Brain; Cholesterol; Cholesterol 24-Hydroxylase; Female; Genetic Predisposition to Disease; Genotype; Humans; Hydroxycholesterols; Introns; Male; Peptide Fragments; Phosphorylation; Polymorphism, Genetic; Risk Factors; Steroid Hydroxylases; tau Proteins | 2003 |
Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Animals; Brain; Female; Humans; Hydroxycholesterols; Male; Mice; Mice, Transgenic; Middle Aged; Mixed Function Oxygenases; Water | 2004 |
24S-hydroxycholesterol: a marker of brain cholesterol metabolism.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Anticholesteremic Agents; Biomarkers; Brain; Brain Chemistry; Child; Child, Preschool; Cholesterol; Dose-Response Relationship, Drug; Humans; Hydroxycholesterols; Hypercholesterolemia; Infant; Middle Aged; Neurodegenerative Diseases; Retrospective Studies | 2003 |
Influence of peroxisome proliferator-activated receptor gamma gene polymorphism on 24S-hydroxycholesterol levels in Alzheimer's patients.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Exons; Female; Genetic Predisposition to Disease; Humans; Hydroxycholesterols; Male; Middle Aged; Mutation, Missense; Polymorphism, Genetic; PPAR gamma; Risk Factors | 2005 |
Polymorphism in neuropeptide Y influences CSF cholesterol levels but is no major risk factor of Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Exons; Female; Genetic Predisposition to Disease; Humans; Hydroxycholesterols; Male; Middle Aged; Neuropeptide Y; Polymorphism, Genetic; Risk Factors | 2006 |
The effects of gender and CYP46 and apo E polymorphism on 24S-hydroxycholesterol levels in Alzheimer's patients treated with statins.
Topics: Aged; Alleles; Alzheimer Disease; Apolipoproteins E; Cholesterol; Cholesterol 24-Hydroxylase; Cholesterol, LDL; Female; Homozygote; Humans; Hydroxycholesterols; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Polymorphism, Genetic; Sex Factors; Steroid Hydroxylases; Sterols | 2004 |
A cluster of cholesterol-related genes confers susceptibility for Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Apolipoprotein A-V; Apolipoproteins; Apolipoproteins A; Apolipoproteins E; Brain; Brain Chemistry; Cholesterol; Cholesterol 24-Hydroxylase; Cross-Cultural Comparison; Female; Genetic Heterogeneity; Genetic Predisposition to Disease; Genetic Testing; Greece; Humans; Hydroxycholesterols; Male; Multigene Family; Polymorphism, Single Nucleotide; Receptors, LDL; Receptors, Oxidized LDL; Risk Factors; Scavenger Receptors, Class E; Steroid Hydroxylases; Switzerland; White People | 2005 |
Polymorphism in ABCA1 influences CSF 24S-hydroxycholesterol levels but is not a major risk factor of Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Cholesterol; Female; Gene Frequency; Genotype; Humans; Hydroxycholesterols; Linkage Disequilibrium; Male; Middle Aged; Multivariate Analysis; Polymorphism, Genetic; Risk Factors | 2006 |
Levels of ApoE in cerebrospinal fluid are correlated with Tau and 24S-hydroxycholesterol in patients with cognitive disorders.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Biomarkers; Brain; Cholesterol; Cognition Disorders; Female; Humans; Hydroxycholesterols; Male; Middle Aged; Nerve Degeneration; Peptide Fragments; Predictive Value of Tests; tau Proteins | 2007 |
Plasma 24S-hydroxycholesterol (cerebrosterol) is increased in Alzheimer and vascular demented patients.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoproteins E; Biomarkers; Case-Control Studies; Cholesterol; Dementia, Vascular; Depression; Diagnosis, Differential; Female; Genotype; Homeostasis; Humans; Hydroxycholesterols; Male; Middle Aged | 2000 |
Plasma 24S-hydroxycholesterol: a peripheral indicator of neuronal degeneration and potential state marker for Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Apolipoproteins E; Biomarkers; Female; Genotype; Humans; Hydroxycholesterols; Male; Nerve Degeneration; Severity of Illness Index | 2000 |
Plasma levels of 24S-hydroxycholesterol in patients with neurological diseases.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Brain Death; Cholesterol; Female; Glioma; Guillain-Barre Syndrome; Humans; Hydroxycholesterols; Liver; Male; Meningitis, Viral; Middle Aged; Multiple Sclerosis; Nervous System Diseases; Sex Factors; Stroke | 2000 |
On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Astrocytes; Axons; Brain; Cholesterol; Cholesterol 24-Hydroxylase; Cytochrome P-450 Enzyme System; Female; Humans; Hydroxycholesterols; Immunohistochemistry; Male; Neuroglia; Neurons; Steroid Hydroxylases | 2001 |
Cerebrospinal fluid 24S-hydroxycholesterol is increased in patients with Alzheimer's disease compared to healthy controls.
Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Protein Precursor; Anticholesteremic Agents; Apolipoproteins E; Body Mass Index; Brain; Cholesterol; Female; Genotype; Humans; Hydroxycholesterols; Hypercholesterolemia; Male; Neurons; Up-Regulation | 2002 |