24-ethyl-4-cholesten-3-one and Arteriosclerosis

24-ethyl-4-cholesten-3-one has been researched along with Arteriosclerosis* in 1 studies

Other Studies

1 other study(ies) available for 24-ethyl-4-cholesten-3-one and Arteriosclerosis

Article	Year
Metabolism of 24-ethyl-4-cholesten-3-one and 24-ethyl-5-cholesten-3 beta-ol (sitosterol) after intraperitoneal injection in the rat. Scandinavian journal of clinical and laboratory investigation. Supplementum, 1986, Volume: 184 14C-labeled C29- and C27-steroids were injected in rats, which were killed after 14 days. Phytosterols (C29) were excreted mainly as such, whereas C27-steroids were recovered essentially as water soluble metabolites. The total 14C-excretion was lower from 3-oxo, delta 4-steroids (5 alpha-stanol precursors) than from 3 beta-hydroxy,delta 5-steroids. 14C-Phytosterols were accumulated more than C27-steroids in liver, serum (mainly in HDL) and especially in adrenal glands and ovaries. In relation to serum, particularly the 5 alpha-stanols were enriched in the adrenal glands and ovaries. No striking lysosomal accumulation of any of the steroids was found. Topics: Animals; Arteriosclerosis; Blood Proteins; Cricetinae; Female; Injections, Intraperitoneal; Lipid Metabolism, Inborn Errors; Liver; Rats; Rats, Inbred Strains; Sitosterols; Subcellular Fractions; Tissue Distribution	1986

Article

Year

Metabolism of 24-ethyl-4-cholesten-3-one and 24-ethyl-5-cholesten-3 beta-ol (sitosterol) after intraperitoneal injection in the rat.

Scandinavian journal of clinical and laboratory investigation. Supplementum, 1986, Volume: 184

14C-labeled C29- and C27-steroids were injected in rats, which were killed after 14 days. Phytosterols (C29) were excreted mainly as such, whereas C27-steroids were recovered essentially as water soluble metabolites. The total 14C-excretion was lower from 3-oxo, delta 4-steroids (5 alpha-stanol precursors) than from 3 beta-hydroxy,delta 5-steroids. 14C-Phytosterols were accumulated more than C27-steroids in liver, serum (mainly in HDL) and especially in adrenal glands and ovaries. In relation to serum, particularly the 5 alpha-stanols were enriched in the adrenal glands and ovaries. No striking lysosomal accumulation of any of the steroids was found.

Topics: Animals; Arteriosclerosis; Blood Proteins; Cricetinae; Female; Injections, Intraperitoneal; Lipid Metabolism, Inborn Errors; Liver; Rats; Rats, Inbred Strains; Sitosterols; Subcellular Fractions; Tissue Distribution

1986