22-hydroxyacuminatine and Neoplasms

22-hydroxyacuminatine has been researched along with Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for 22-hydroxyacuminatine and Neoplasms

ArticleYear
Synthesis and bioevaluation of 22-hydroxyacuminatine analogs.
    Bioorganic & medicinal chemistry letters, 2008, Mar-15, Volume: 18, Issue:6

    A series of 22-hydroxyacuminatine analogs was prepared by using different Friedländer condensations. Several of the new compounds were tested for antiproliferative activity on cancer cell lines and for topoisomerase I inhibitory activity.

    Topics: Antineoplastic Agents; DNA Topoisomerases, Type I; Humans; Indolizines; Molecular Structure; Neoplasms; Quinolines; Structure-Activity Relationship; Topoisomerase I Inhibitors; Tumor Cells, Cultured

2008