Compounds > 21-deoxycortisol
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21-deoxycortisol and Congenital Adrenal Hyperplasia

21-deoxycortisol has been researched along with Congenital Adrenal Hyperplasia in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199013 (30.95)18.7374
1990's5 (11.90)18.2507
2000's7 (16.67)29.6817
2010's10 (23.81)24.3611
2020's7 (16.67)2.80

Authors

AuthorsStudies
Allen, DB; Bialk, ER; Held, PK; Lasarev, MR1
Gau, M; Hasegawa, T; Hashimoto, A; Ishige, N; Kashimada, K; Konishi, K; Morio, T; Nakatani, H; Sutani, A; Tajima, T; Takasawa, K; Tsuji-Hosokawa, A; Watanabe, K; Yajima, H1
Beilby, JP; Brown, SJ; Lim, EM; Ng, JL; Stuckey, BGA; Watts, GF; Zhang, R1
Miller, WL1
Bouvattier, C; Fagart, J; Lombès, M; Martinerie, L; Pussard, E; Travers, S; Viengchareun, S1
Baráth, Á; Bereczki, C; Galla, Z; Grecsó, N; Monostori, P; Rácz, G; Zádori, A1
Ackermans, M; Bocca, G; Boelen, A; Bosch, AM; Bouva, MJ; Claahsen-van der Grinten, HL; de Jonge, R; Engel, H; Finken, MJJ; Hannema, SE; Heijboer, AC; Jakobs, B; Kemper, EA; Mieke Houdijk, ECA; Paul van Trotsenburg, AS; Ruiter, A; Stroek, K; van Albada, ME; van den Akker, ELT; van der Kamp, HJ; van der Linde, A; van Tellingen, V; Zwaveling-Soonawala, N1
Carvalho, VM; Costa-Barbosa, FA; Kater, CE; Oliveira, KC; Vieira, JGH1
Auchus, RJ; Avila, NA; Elman, MS; Mallappa, A; Marko, J; Merke, DP; Rao, H; Tsodikov, A; Turcu, AF1
Akkurt, HI; Borzikowsky, C; Flader, M; Heger, S; Holterhus, PM; Hornig, N; Kulle, AE; Niedziela, M; Reinehr, T; Simic-Schleicher, G; Zalas, D1
Boettcher, C; Hartmann, MF; Kamrath, C; Wudy, SA1
Auchus, RJ; Chomic, R; Else, T; Liu, J; Moraitis, AG; Nishimoto, HK; Palapattu, GS; Rainey, WE; Rege, J; Turcu, AF1
Claahsen-van der Grinten, HL; Engels, M; Griffin, A; Krone, N; Mooij, CF; Pijnenburg-Kleizen, KJ; Span, PN; Sweep, FC; van Herwaarden, AE1
Hedderich, J; Holterhus, PM; Kulle, AE; Niermeyer, L; Riepe, FG; Schmitz, J; Sippell, WG1
De Mello, MP; Kater, CE; Lemos-Marini, SH; Ribeiro-Neto, LM; Tonetto-Fernandes, V1
Bachega, TA; Carvalho, VM; Costa-Barbosa, FA; Kater, CE; Moura, V; Nakamura, OH; Tonetto-Fernandes, VF; Vieira, JG1
Bachega, TA; Carvalho, VM; Costa-Barbosa, FA; Kater, CE; Nakamura, OH; Vieira, JG1
Brack, C; Heger, S; Janzen, N; Korsch, E; Krull, F; Müller, HL; Peter, M; Riepe, FG; Sander, J; Sander, S; Steuerwald, U1
Bernardi, LR; Biunno, I; Cristoni, S; Cuccato, D; Gerthoux, P; Mora, S; Russo, G; Sciannamblo, M; Weber, G1
Kater, CE; Kuperman, H; Lemos-Marini, SH; Ribeiro-Neto, LM; Tonetto-Fernandes, V; Verreschi, IT1
Gallwitz, B; Häring, HU; Hartmann, MF; Horger, M; Kaltenbach, S; Maser-Gluth, C; Müssig, K; Raue, F; Schulze, E; Wudy, SA1
Holtkamp, U; Janzen, N; Peter, M; Sander, J; Sander, S; Steuerwald, U; Terhardt, M1
Kanbegawa, A; Murata, M; Murata, T1
Conway, GS; Holmes-Walker, DJ; Honour, JW; Jacobs, HS; Rumsby, G1
Afelska, A; Milewicz, A; Romer, T; Wasikowa, R1
Boudou, P; Burthier, JM; Fiet, J; Galons, H; Gourmelen, M; Hardy, N; Julien, R; Soliman, H; Vexiau, P; Villette, JM1
Bellanné-Chantelot, C; Blanché, H; Clauin, S; Dausset, J; Fiet, J; Le Gall, I; Mornet, E; Vexiau, P1
Chabre, O; Defaye, G; Morel, Y; Portrat-Doyen, S; Vivier, J1
Kao, PC; Lacey, JM; Machacek, DA; Magera, MJ; Rinaldo, P1
Saisho, S; Shimozawa, K; Yata, J1
Brerault, JL; Couillin, P; Fiet, J; Gourmelen, M; Gueux, B; Kuttenn, F; Mornet, E; Raux-Demay, MC; Vexiau, P; Villette, JM1
Adams, J; Hague, WM; Honour, JW; Jacobs, HS; Vecsei, P1
Brerault, JL; Couillin, P; Fiet, J; Galons, H; Gueux, B; Julien, R; Kuttenn, F; Raux-DeMay, MC; Vexiau, P; Villette, JM1
Fiet, J; Girard, F; Gourmelen, M; Gueux, B; Pham Huu Trung, MT; Raux-Demay, MC1
Couillin, P; Fiet, J; Galons, H; Gourmelen, M; Gueux, B; Kuttenn, F; Pham-Huu-Trung, MT; Raux-Demay, MC; Vexiau, P; Villette, JM1
Gautier, T; Imperato-McGinley, J; Peterson, RE; Shackleton, C1
Brerault, JL; Fiet, J; Galons, H; Gourmelen, M; Gueux, B; Julien, R; Pham-Huu-Trung, MT; Vexiau, P; Villette, JM1
Boue, J; Couillin, P; Dreux, C; Fiet, J; Galons, H; Gueux, B; Mornet, E; Raux-Demay, MC; Villette, JM1
Boneté, R; Brérault, JL; Fiet, J; Galons, H; Gourmelen, M; Gueux, B; Pham-Huu-Trung, MT; Raux-Eurin, MC; Vexiau, P; Villette, JM1
Hikita, Y1
Arakawa, H; Maeda, M; Tsuji, A1
Franks, RC1

Reviews

2 review(s) available for 21-deoxycortisol and Congenital Adrenal Hyperplasia

ArticleYear
Congenital Adrenal Hyperplasia: Time to Replace 17OHP with 21-Deoxycortisol.
    Hormone research in paediatrics, 2019, Volume: 91, Issue:6

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Cortodoxone; Female; Humans; Infant; Infant, Newborn; Male; Neonatal Screening

2019
21-hydroxylase deficiency transiently mimicking combined 21- and 11beta-hydroxylase deficiency.
    Journal of pediatric endocrinology & metabolism : JPEM, 2008, Volume: 21, Issue:5

    Topics: Adrenal Hyperplasia, Congenital; Androstenedione; Child; Cortodoxone; Diagnosis, Differential; Female; Humans; Mutation; Steroid 11-beta-Hydroxylase; Steroid 21-Hydroxylase

2008

Trials

3 trial(s) available for 21-deoxycortisol and Congenital Adrenal Hyperplasia

ArticleYear
Multiples of Median-Transformed, Normalized Reference Ranges of Steroid Profiling Data Independent of Age, Sex, and Units.
    Hormone research in paediatrics, 2018, Volume: 89, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Adrenocortical Carcinoma; Age Factors; Child; Child, Preschool; Chromatography, Liquid; Cortodoxone; Female; Humans; Infant; Infant, Newborn; Male; Mass Spectrometry; Obesity; Sex Factors

2018
Superior discriminating value of ACTH-stimulated serum 21-deoxycortisol in identifying heterozygote carriers for 21-hydroxylase deficiency.
    Clinical endocrinology, 2010, Volume: 73, Issue:6

    Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Child; Child, Preschool; Chromatography, Liquid; Cortodoxone; Female; Genetic Carrier Screening; Humans; Male; Middle Aged; Mutation; Steroid 21-Hydroxylase; Tandem Mass Spectrometry; Young Adult

2010
Newborn screening for congenital adrenal hyperplasia: additional steroid profile using liquid chromatography-tandem mass spectrometry.
    The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:7

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Androstenedione; Calibration; Chromatography, High Pressure Liquid; Cortodoxone; False Positive Reactions; Female; Humans; Hydrocortisone; Infant, Newborn; Infant, Premature; Male; Neonatal Screening; Prospective Studies; Reproducibility of Results; Retrospective Studies; Tandem Mass Spectrometry

2007

Other Studies

37 other study(ies) available for 21-deoxycortisol and Congenital Adrenal Hyperplasia

ArticleYear
21-Deoxycortisol is a Key Screening Marker for 21-Hydroxylase Deficiency.
    The Journal of pediatrics, 2022, Volume: 242

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Biomarkers; Cortodoxone; Female; Humans; Infant; Infant, Newborn; Male; Neonatal Screening

2022
The High Relevance of 21-Deoxycortisol, (Androstenedione + 17α-Hydroxyprogesterone)/Cortisol, and 11-Deoxycortisol/17α-Hydroxyprogesterone for Newborn Screening of 21-Hydroxylase Deficiency.
    The Journal of clinical endocrinology and metabolism, 2022, 11-25, Volume: 107, Issue:12

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Androgens; Androstenedione; Chromatography, Liquid; Cortodoxone; Endocrine System Diseases; Female; Humans; Hydrocortisone; Infant, Newborn; Male; Neonatal Screening; Steroids; Tandem Mass Spectrometry

2022
Serum 21-Deoxycortisol for Diagnosis of Nonclassic Congenital Adrenal Hyperplasia in Women With Androgen Excess.
    The Journal of clinical endocrinology and metabolism, 2023, Nov-17, Volume: 108, Issue:12

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Androgens; Chromatography, Liquid; Cortodoxone; Cosyntropin; Cross-Sectional Studies; Female; Humans; Steroid 21-Hydroxylase; Tandem Mass Spectrometry

2023
Interaction between accumulated 21-deoxysteroids and mineralocorticoid signaling in 21-hydroxylase deficiency.
    American journal of physiology. Endocrinology and metabolism, 2020, 02-01, Volume: 318, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Hyperplasia, Congenital; Child; Child, Preschool; Cohort Studies; Cortodoxone; Female; HEK293 Cells; Humans; Hydrocortisone; Infant; Male; Mineralocorticoids; Molecular Docking Simulation; Receptors, Mineralocorticoid; Signal Transduction; Steroids; Young Adult

2020
Comparison of different preparation techniques of dried blood spot quality controls in newborn screening for congenital adrenal hyperplasia.
    PloS one, 2021, Volume: 16, Issue:5

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Androstenedione; Cortodoxone; Dried Blood Spot Testing; Humans; Infant, Newborn; Neonatal Screening; Tandem Mass Spectrometry

2021
Second-tier Testing for 21-Hydroxylase Deficiency in the Netherlands: A Newborn Screening Pilot Study.
    The Journal of clinical endocrinology and metabolism, 2021, 10-21, Volume: 106, Issue:11

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Algorithms; Cortodoxone; False Positive Reactions; Humans; Infant, Newborn; Neonatal Screening; Netherlands; Pilot Projects; Sensitivity and Specificity

2021
Reassessment of predictive values of ACTH-stimulated serum 21-deoxycortisol and 17-hydroxyprogesterone to identify CYP21A2 heterozygote carriers and nonclassic subjects.
    Clinical endocrinology, 2021, Volume: 95, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Chromatography, Liquid; Cortodoxone; Heterozygote; Humans; Prospective Studies; Steroid 21-Hydroxylase; Tandem Mass Spectrometry

2021
11-Oxygenated Androgens Are Biomarkers of Adrenal Volume and Testicular Adrenal Rest Tumors in 21-Hydroxylase Deficiency.
    The Journal of clinical endocrinology and metabolism, 2017, 08-01, Volume: 102, Issue:8

    Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenal Rest Tumor; Adult; Age Determination by Skeleton; Aged; Androgens; Androstenedione; Androstenes; Child; Child, Preschool; Cortodoxone; Cross-Sectional Studies; Female; Hirsutism; Humans; Hydroxytestosterones; Male; Menstruation Disturbances; Middle Aged; Organ Size; Pregnenolone; Testicular Neoplasms; Testosterone; Young Adult

2017
Reduced activity of 11β-hydroxylase accounts for elevated 17α-hydroxyprogesterone in preterms.
    The Journal of pediatrics, 2014, Volume: 165, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Chromatography, Gas; Cortodoxone; Female; Gas Chromatography-Mass Spectrometry; Humans; Infant; Infant, Newborn; Infant, Premature; Male; Mass Spectrometry; Metabolome; Pregnanetriol; Retrospective Studies; Steroid 11-beta-Hydroxylase; Steroid 17-alpha-Hydroxylase

2014
Profiles of 21-Carbon Steroids in 21-hydroxylase Deficiency.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:6

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adrenal Rest Tumor; Adult; Case-Control Studies; Cells, Cultured; Cortodoxone; Female; Humans; Hydroxyprogesterones; Male; Metabolome; Middle Aged; Progesterone; Testicular Neoplasms; Young Adult

2015
Adrenal Steroid Metabolites Accumulating in Congenital Adrenal Hyperplasia Lead to Transactivation of the Glucocorticoid Receptor.
    Endocrinology, 2015, Volume: 156, Issue:10

    Topics: 17-alpha-Hydroxyprogesterone; Active Transport, Cell Nucleus; Adrenal Glands; Adrenal Hyperplasia, Congenital; Androstenedione; Animals; Binding, Competitive; Chlorocebus aethiops; Cortodoxone; COS Cells; Glucocorticoids; Green Fluorescent Proteins; HEK293 Cells; HeLa Cells; Humans; Microscopy, Fluorescence; Progesterone; Protein Binding; Receptors, Glucocorticoid; Steroids; Transcriptional Activation

2015
LC-MS/MS based determination of basal- and ACTH-stimulated plasma concentrations of 11 steroid hormones: implications for detecting heterozygote CYP21A2 mutation carriers.
    European journal of endocrinology, 2015, Volume: 173, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Aged; Androstenedione; Case-Control Studies; Child; Chromatography, Liquid; Corticosterone; Cortisone; Cortodoxone; Desoxycorticosterone; Dihydrotestosterone; Female; Genetic Carrier Screening; Hormones; Humans; Hydrocortisone; Male; Middle Aged; Progesterone; Steroid 21-Hydroxylase; Tandem Mass Spectrometry; Testosterone; Young Adult

2015
Zona fasciculata 21-hydroxysteroids and precursor-to-product ratios in 21-hydroxylase deficiency: further characterization of classic and non-classic patients and heterozygote carriers.
    Journal of endocrinological investigation, 2011, Volume: 34, Issue:8

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adult; Carrier State; Corticosterone; Cortodoxone; Female; Heterozygote; Humans; Male; Middle Aged; Steroid 21-Hydroxylase; Young Adult; Zona Fasciculata

2011
Neonatal screening: identification of children with 11β-hydroxylase deficiency by second-tier testing.
    Hormone research in paediatrics, 2012, Volume: 77, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Androstenedione; Cortodoxone; False Positive Reactions; Female; Humans; Hydrocortisone; Infant; Infant, Newborn; Male; Neonatal Screening; Steroid 11-beta-Hydroxylase

2012
Analysis of 21-deoxycortisol, a marker of congenital adrenal hyperplasia, in blood by atmospheric pressure chemical ionization and electrospray ionization using multiple reaction monitoring.
    Rapid communications in mass spectrometry : RCM, 2004, Volume: 18, Issue:1

    Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Atmospheric Pressure; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Cortodoxone; Female; Genetic Testing; Humans; Male; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2004
Serum 21-Deoxycortisol, 17-Hydroxyprogesterone, and 11-deoxycortisol in classic congenital adrenal hyperplasia: clinical and hormonal correlations and identification of patients with 11beta-hydroxylase deficiency among a large group with alleged 21-hydrox
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:6

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Hyperplasia, Congenital; Adult; Child; Child, Preschool; Cortodoxone; Female; Humans; Infant; Infant, Newborn; Male; Steroid 11-beta-Hydroxylase; Steroid 21-Hydroxylase

2006
Late diagnosis of congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2006, Volume: 114, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adult; Androgens; Cortodoxone; Exons; Humans; Infertility, Male; Male; Point Mutation; Steroid 21-Hydroxylase

2006
[Simultaneous determination of plasma 17 alpha-hydroxyprogesterone, 21-deoxycortisol and cortisol by 125I cortisol kit on congenital adrenal hyperplasia (author's transl)].
    Horumon to rinsho. Clinical endocrinology, 1981, Volume: 29, Issue:3

    Topics: 17-Hydroxycorticosteroids; Adrenal Hyperplasia, Congenital; Cortodoxone; Humans; Hydrocortisone; Hydroxyprogesterones; Iodine Radioisotopes; Reagent Kits, Diagnostic

1981
Menstrual disturbance and hypersecretion of progesterone in women with congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
    Clinical endocrinology, 1995, Volume: 43, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Hyperplasia, Congenital; Adult; Amenorrhea; Cortodoxone; Female; Humans; Hydroxyprogesterones; Male; Progesterone; Steroid 21-Hydroxylase

1995
Evaluation of 21-deoxycortisol as a marker for the detection of heterozygous carriers of 21-hydroxylase deficiency.
    Endokrynologia Polska, 1993, Volume: 44, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Biomarkers; Cortodoxone; Female; Genetic Carrier Screening; Humans; Hydroxyprogesterones; Isomerism; Male; Middle Aged; Sensitivity and Specificity

1993
The application of a new highly-sensitive radioimmunoassay for plasma 21-deoxycortisol to the detection of steroid-21-hydroxylase deficiency.
    Annals of clinical biochemistry, 1994, Volume: 31 ( Pt 1)

    Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adult; Antibodies, Monoclonal; Child; Chromatography, High Pressure Liquid; Cortodoxone; Female; Heterozygote; Humans; Male; Radioimmunoassay; Reproducibility of Results; Sensitivity and Specificity

1994
Exhaustive screening of the 21-hydroxylase gene in a population of hyperandrogenic women.
    Human genetics, 1997, Volume: 101, Issue:1

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Alleles; Base Sequence; Child; Cortodoxone; DNA Primers; Female; Genetic Counseling; Genetic Testing; Genotype; Heterozygote; Hirsutism; Homozygote; Humans; Hyperandrogenism; Middle Aged; Mutation; Phenotype; Polymerase Chain Reaction; Steroid 21-Hydroxylase

1997
Two novel mutations in splice donor sites of CYP11B1 in congenital adrenal hyperplasia due to 11beta-hydroxylase deficiency.
    Endocrine research, 2000, Volume: 26, Issue:4

    Topics: Adrenal Cortex; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adult; Cortodoxone; DNA; DNA, Complementary; DNA, Recombinant; Female; Genome; Humans; Hydrocortisone; Metabolism, Inborn Errors; Mutation; RNA, Messenger; Steroid 11-beta-Hydroxylase

2000
Diagnosis of adrenal cortical dysfunction by liquid chromatography-tandem mass spectrometry.
    Annals of clinical and laboratory science, 2001, Volume: 31, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Addison Disease; Adrenal Cortex Diseases; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Aged; Chromatography, Liquid; Cortisone; Cortodoxone; Desoxycorticosterone; Female; Humans; Hydrocortisone; Male; Mass Spectrometry; Metyrapone; Middle Aged

2001
Changes of several adrenal delta 4-steroids measured by HPLC-UV spectrometry in neonatal patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
    Hormone research, 1990, Volume: 33, Issue:1

    Topics: 17-alpha-Hydroxyprogesterone; 17-Hydroxycorticosteroids; Adrenal Hyperplasia, Congenital; Chromatography, High Pressure Liquid; Cortisone; Cortodoxone; Female; Humans; Hydroxyprogesterones; Infant, Newborn; Male; Steroid Hydroxylases; Time Factors

1990
[21-deoxycortisol. A new marker of virilizing adrenal hyperplasia caused by 21-hydroxylase deficiency].
    Presse medicale (Paris, France : 1983), 1989, Dec-02, Volume: 18, Issue:40

    Topics: 17-alpha-Hydroxyprogesterone; 17-Hydroxycorticosteroids; Adrenal Hyperplasia, Congenital; Adult; Amniotic Fluid; Biomarkers; Child; Cortodoxone; Cosyntropin; Female; Heterozygote; Humans; Hydroxyprogesterones; Infant, Newborn; Male; Mixed Function Oxygenases; Prenatal Diagnosis; Radioimmunoassay

1989
Steroid responses to ACTH in women with polycystic ovaries.
    Clinical endocrinology, 1989, Volume: 30, Issue:4

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adult; Cortodoxone; Cosyntropin; Dehydroepiandrosterone; Female; Heterozygote; Humans; Hydroxyprogesterones; Middle Aged; Polycystic Ovary Syndrome; Steroids

1989
Increased plasma 21-deoxycorticosterone (21-DB) levels in late-onset adrenal 21-hydroxylase deficiency suggest a mild defect of the mineralocorticoid pathway.
    The Journal of clinical endocrinology and metabolism, 1989, Volume: 68, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Child; Cortodoxone; Desoxycorticosterone; Female; Heterozygote; Humans; Hydroxyprogesterones; Male; Middle Aged; Steroid Hydroxylases

1989
Detection of heterozygous carriers for 21-hydroxylase deficiency by plasma 21-deoxycortisol measurement.
    Acta endocrinologica, 1987, Volume: 116, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; 17-Hydroxycorticosteroids; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Cortodoxone; Female; Genetic Carrier Screening; HLA Antigens; HLA-B Antigens; HLA-B14 Antigen; Humans; Hydroxyprogesterones; Male; Steroid Hydroxylases

1987
Comparison of basal and adrenocorticotropin-stimulated plasma 21-deoxycortisol and 17-hydroxyprogesterone values as biological markers of late-onset adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1988, Volume: 66, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; 17-Hydroxycorticosteroids; Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Child; Child, Preschool; Cortodoxone; Female; Heterozygote; HLA Antigens; Humans; Hydroxyprogesterones; Infant; Male; Menstrual Cycle; Middle Aged; Reference Values

1988
Male pseudohermaphroditism due to multiple defects in steroid-biosynthetic microsomal mixed-function oxidases. A new variant of congenital adrenal hyperplasia.
    The New England journal of medicine, 1985, Nov-07, Volume: 313, Issue:19

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Adrenal Hyperplasia, Congenital; Aldehyde-Lyases; Aldosterone; Androstenedione; Corticosterone; Cortodoxone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Dihydrotestosterone; Disorders of Sex Development; Humans; Hydrocortisone; Infant; Male; Mixed Function Oxygenases; Pregnenolone; Progesterone; Steroid Hydroxylases; Testosterone

1985
Radioimmunoassay for 21-deoxycortisol: clinical applications.
    Acta endocrinologica, 1985, Volume: 108, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; 17-Hydroxycorticosteroids; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Cortodoxone; Cross Reactions; Female; Haptens; Humans; Hydroxyprogesterones; Immune Sera; Male; Middle Aged; Radioimmunoassay

1985
Prenatal diagnosis of 21-hydroxylase deficiency congenital adrenal hyperplasia by simultaneous radioimmunoassay of 21-deoxycortisol and 17-hydroxyprogesterone in amniotic fluid.
    The Journal of clinical endocrinology and metabolism, 1988, Volume: 66, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; 17-Hydroxycorticosteroids; Adrenal Hyperplasia, Congenital; Amniotic Fluid; Cortodoxone; Female; HLA Antigens; Humans; Hydroxyprogesterones; Pregnancy; Prenatal Diagnosis; Radioimmunoassay; Steroid Hydroxylases

1988
The measurement of 11 beta-hydroxy-4-pregnene-3,20-dione (21-deoxycorticosterone) by radioimmunoassay in human plasma.
    Journal of steroid biochemistry, 1987, Volume: 26, Issue:1

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Hyperplasia, Congenital; Adult; Antibody Specificity; Child; Child, Preschool; Cortodoxone; Cross Reactions; Desoxycorticosterone; Female; Humans; Hydroxyprogesterones; Male; Radioimmunoassay; Renin

1987
[Reevaluation of recalled infants by neonatal mass screening for congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Diagnostic value of pregnanetriolone in a single urine specimen using glass capillary gas chromatography].
    Nihon Naibunpi Gakkai zasshi, 1985, Mar-20, Volume: 61, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Chromatography, Gas; Cortodoxone; Female; Follow-Up Studies; Humans; Hydroxyprogesterones; Male; Mass Screening; Pregnancy; Pregnanetriol; Steroid Hydroxylases

1985
Fluorescence enzyme immunoassay of 21-deoxycortisol in plasma and dried blood sample on filter paper.
    Journal of immunoassay, 1985, Volume: 6, Issue:4

    Topics: 17-Hydroxycorticosteroids; Adrenal Hyperplasia, Congenital; Antibody Specificity; Cortodoxone; Cross Reactions; Humans; Immunoenzyme Techniques; Mass Screening; Paper; Steroid 11-beta-Hydroxylase; Steroid 21-Hydroxylase; Steroid Hydroxylases

1985
Plasma 17-hydroxyprogesterone, 21-deoxycortisol and cortisol in congenital adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1974, Volume: 39, Issue:6

    Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Adult; Child; Child, Preschool; Cortisone; Cortodoxone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Immune Sera; Infant; Male; Mixed Function Oxygenases; Prednisone; Pregnadienediols; Radioimmunoassay; Tritium

1974