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20-hydroxy-5,8,11,14-eicosatetraenoic acid and Stroke

20-hydroxy-5,8,11,14-eicosatetraenoic acid has been researched along with Stroke in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (23.53)29.6817
2010's13 (76.47)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Booz, GW; Fan, F; Fan, L; Li, M; Roman, RJ; Shekhar, S; Varghese, K1
Booz, GW; Cunningham, MW; Fan, F; Pabbidi, MR; Shekhar, S; Wang, S1
Cheng, G; Li, J; Li, Y; Li, Z; Liu, Y; Lu, L; Teng, G; Zhan, M1
Attwell, D; Buchan, AM; Gesslein, B; Hall, CN; Hamilton, NB; Lauritzen, M; Mishra, A; O'Farrell, FM; Reynell, C; Sutherland, BA1
Ergul, A; Hoda, MN; Li, W; Luo, P; Maddipati, KR; Seki, T; Wang, MH; Zhang, Y; Zheng, X1
Chen, H; Li, J; Liao, D; Wang, C; Wu, L; Yi, X1
Al-Shabrawey, M; Huang, H; Wang, MH1
Liao, D; Lin, J; Yi, X; Zhang, B; Zhou, Q1
Liao, D; Wang, C; Wu, L; Yi, X; Zhang, B1
Booz, GW; Elliott, MR; Fan, F; Ge, Y; Hirata, T; Lv, W; Muroya, Y; Roman, RJ1
Han, Z; Lin, J; Liu, P; Yi, X; Zhou, Q1
Lin, J; Wang, C; Yi, X; Zhou, Q1
Almgren, P; Berglund, G; Engström, G; Fava, C; Hedblad, B; Lippi, G; Melander, O; Minuz, P; Montagnana, M; Rosberg, L1
Dunn, KM; Falck, J; Flasch, AK; Harder, DR; Renic, M; Roman, RJ1
Barden, A; Beer, CD; Blacker, D; Croft, KD; Hankey, GJ; Mori, TA; Puddey, IB; Ward, NC1
Bandou, K; Cambj-Sapunar, L; Doi, M; Harder, DR; Kametani, S; Miyata, N; Okuyama, S; Omura, T; Roman, RJ; Sato, M; Seki, T; Tanaka, Y; Taniguchi, K1
Bies, RR; Graham, SH; Kochanek, PM; Poloyac, SM; Zhang, Y1

Reviews

4 review(s) available for 20-hydroxy-5,8,11,14-eicosatetraenoic acid and Stroke

ArticleYear
Conflicting Roles of 20-HETE in Hypertension and Stroke.
    International journal of molecular sciences, 2019, Sep-11, Volume: 20, Issue:18

    Topics: Animals; Disease Progression; Humans; Hydroxyeicosatetraenoic Acids; Hypertension; Models, Biological; Polymorphism, Genetic; Stroke

2019
Targeting vascular inflammation in ischemic stroke: Recent developments on novel immunomodulatory approaches.
    European journal of pharmacology, 2018, Aug-15, Volume: 833

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Endothelial Cells; Genetic Therapy; Humans; Hydroxyeicosatetraenoic Acids; Hyperbaric Oxygenation; Immunomodulation; Inflammation; Macrophages; Microglia; MicroRNAs; Neuroprotective Agents; Oligonucleotides; Oxidative Stress; Signal Transduction; Stroke

2018
Cyclooxygenase- and cytochrome P450-derived eicosanoids in stroke.
    Prostaglandins & other lipid mediators, 2016, Volume: 122

    Topics: Arachidonic Acid; Cytochrome P-450 Enzyme System; Eicosanoids; Humans; Hydroxyeicosatetraenoic Acids; Models, Biological; Prostaglandin-Endoperoxide Synthases; Receptors, Prostaglandin E; Stroke; Subarachnoid Hemorrhage

2016
Molecular mechanisms and cell signaling of 20-hydroxyeicosatetraenoic acid in vascular pathophysiology.
    Frontiers in bioscience (Landmark edition), 2016, 06-01, Volume: 21, Issue:7

    Topics: Animals; Blood Vessels; Brain Injuries, Traumatic; Endothelium, Vascular; Humans; Hydroxyeicosatetraenoic Acids; Muscle, Smooth, Vascular; Neovascularization, Physiologic; Platelet Aggregation; Reperfusion Injury; Signal Transduction; Stroke; Subarachnoid Hemorrhage; Vasculitis

2016

Other Studies

13 other study(ies) available for 20-hydroxy-5,8,11,14-eicosatetraenoic acid and Stroke

ArticleYear
Astrocytic cytochrome P450 4A/20-hydroxyeicosatetraenoic acid contributes to angiogenesis in the experimental ischemic stroke.
    Brain research, 2019, 04-01, Volume: 1708

    Topics: Angiogenesis Inducing Agents; Animals; Astrocytes; Brain Ischemia; Cell Proliferation; Cytochrome P-450 CYP4A; Disease Models, Animal; Endothelial Cells; Hydroxyeicosatetraenoic Acids; Male; Mice; Mice, Inbred C57BL; Microcirculation; Neovascularization, Pathologic; Stroke; Vascular Endothelial Growth Factor A

2019
Capillary pericytes regulate cerebral blood flow in health and disease.
    Nature, 2014, Apr-03, Volume: 508, Issue:7494

    Topics: Animals; Arterioles; Blood-Brain Barrier; Brain Ischemia; Capillaries; Cell Death; Cerebellum; Cerebral Cortex; Cerebrovascular Circulation; Dinoprostone; Excitatory Amino Acid Antagonists; Female; Functional Neuroimaging; Glutamic Acid; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Pericytes; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Glutamate; Signal Transduction; Stroke; Vasoconstriction; Vasodilation

2014
Combined therapy with COX-2 inhibitor and 20-HETE inhibitor reduces colon tumor growth and the adverse effects of ischemic stroke associated with COX-2 inhibition.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2014, Sep-15, Volume: 307, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Ischemia; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytochrome P-450 CYP4A; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Lactones; Male; Mice; Mice, Inbred C57BL; Rats; Stroke; Sulfones; Time Factors; Tumor Burden

2014
CYP Genetic Variants, CYP Metabolite Levels, and Symptomatic Carotid Stenosis in Ischemic Stroke Patients.
    Journal of atherosclerosis and thrombosis, 2016, May-02, Volume: 23, Issue:5

    Topics: Aged; Arachidonic Acids; Brain Ischemia; Carotid Arteries; Carotid Stenosis; Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Female; Genetic Variation; Genotype; Humans; Hydroxyeicosatetraenoic Acids; Male; Middle Aged; Polymorphism, Single Nucleotide; Risk; Stroke; Ultrasonography

2016
Interaction Between CYP4F2 rs2108622 and CPY4A11 rs9333025 Variants Is Significantly Correlated with Susceptibility to Ischemic Stroke and 20-Hydroxyeicosatetraenoic Acid Level.
    Genetic testing and molecular biomarkers, 2016, Volume: 20, Issue:5

    Topics: Aged; Brain Ischemia; Case-Control Studies; Cytochrome P-450 CYP4A; Cytochrome P450 Family 4; Epistasis, Genetic; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Hydroxyeicosatetraenoic Acids; Male; Middle Aged; Polymorphism, Single Nucleotide; Stroke

2016
Interactions Among CYP2C8, EPHX2, and CYP4A11 Variants and CYP Plasma Metabolite Levels in Ischemic Stroke.
    Journal of atherosclerosis and thrombosis, 2016, Nov-01, Volume: 23, Issue:11

    Topics: Aged; Biomarkers; Brain Ischemia; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP4A; Epoxide Hydrolases; Female; Follow-Up Studies; Genetic Variation; Genotype; Humans; Hydroxyeicosatetraenoic Acids; Male; Prognosis; Stroke

2016
20-Hydroxyeicosatetraenoic Acid as a Predictor of Neurological Deterioration in Acute Minor Ischemic Stroke.
    Stroke, 2016, Volume: 47, Issue:12

    Topics: Brain Ischemia; Disease Progression; Humans; Hydroxyeicosatetraenoic Acids; Prognosis; Prospective Studies; Stroke

2016
CYP Genetic Variants, CYP Metabolite Levels, and Neurologic Deterioration in Acute Ischemic Stroke in Chinese Population.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2017, Volume: 26, Issue:5

    Topics: Aged; Aged, 80 and over; Asian People; Biomarkers; Brain Ischemia; Chi-Square Distribution; China; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Eicosanoids; Epoxide Hydrolases; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Hydroxyeicosatetraenoic Acids; Male; Middle Aged; Nerve Degeneration; Odds Ratio; Phenotype; Polymorphism, Single Nucleotide; Prospective Studies; Risk Factors; Stroke; Time Factors

2017
The V433M variant of the CYP4F2 is associated with ischemic stroke in male Swedes beyond its effect on blood pressure.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 52, Issue:2

    Topics: Analysis of Variance; Anthropometry; Brain Ischemia; Cohort Studies; Cytochrome P-450 CYP4A; Female; Gene Expression Regulation; Genetic Predisposition to Disease; Genotype; Heterozygote; Humans; Hydroxyeicosatetraenoic Acids; Hypertension; Kaplan-Meier Estimate; Male; Middle Aged; Polymorphism, Genetic; Probability; Proportional Hazards Models; Sex Factors; Stroke

2008
Elevated production of 20-HETE in the cerebral vasculature contributes to severity of ischemic stroke and oxidative stress in spontaneously hypertensive rats.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:6

    Topics: Amidines; Animals; Blood Pressure; Cerebral Arteries; Cerebrovascular Circulation; Cytochrome P-450 CYP4A; Disease Models, Animal; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Hypertension; Infarction, Middle Cerebral Artery; Isoenzymes; Male; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Severity of Illness Index; Stroke; Time Factors; Up-Regulation

2008
Cytochrome P450 metabolites of arachidonic acid are elevated in stroke patients compared with healthy controls.
    Clinical science (London, England : 1979), 2011, Volume: 121, Issue:11

    Topics: 8,11,14-Eicosatrienoic Acid; Arachidonic Acid; Case-Control Studies; Cytochrome P-450 Enzyme System; F2-Isoprostanes; Female; Humans; Hydroxyeicosatetraenoic Acids; Male; Middle Aged; Oxidative Stress; Stroke

2011
Beneficial effects of a new 20-hydroxyeicosatetraenoic acid synthesis inhibitor, TS-011 [N-(3-chloro-4-morpholin-4-yl) phenyl-N'-hydroxyimido formamide], on hemorrhagic and ischemic stroke.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:1

    Topics: Animals; Brain; Carotid Arteries; Cerebral Hemorrhage; Cerebral Infarction; Cerebrovascular Circulation; Collagenases; Cytochrome P-450 CYP4A; Formamides; Hydroxyeicosatetraenoic Acids; Infarction, Middle Cerebral Artery; Infusions, Intra-Arterial; Isoenzymes; Male; Morpholines; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Stroke

2005
Protective effect of the 20-HETE inhibitor HET0016 on brain damage after temporary focal ischemia.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2006, Volume: 26, Issue:12

    Topics: Amidines; Animals; Brain Injuries; Brain Ischemia; Cerebrovascular Circulation; Cytochrome P-450 Enzyme System; Hydroxyeicosatetraenoic Acids; Male; Microsomes; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stroke; Vasoconstriction

2006