20-hydroxy-5,8,11,14-eicosatetraenoic acid and Cerebral Ischemia

20-hydroxy-5,8,11,14-eicosatetraenoic acid has been researched along with Cerebral Ischemia in 22 studies

Research

Studies (22)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (4.55)	18.2507
2000's	7 (31.82)	29.6817
2010's	14 (63.64)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Booz, GW; Cunningham, MW; Fan, F; Pabbidi, MR; Shekhar, S; Wang, S	1
Cheng, G; Li, J; Li, Y; Li, Z; Liu, Y; Lu, L; Teng, G; Zhan, M	1
Attwell, D; Buchan, AM; Gesslein, B; Hall, CN; Hamilton, NB; Lauritzen, M; Mishra, A; O'Farrell, FM; Reynell, C; Sutherland, BA	1
Ergul, A; Hoda, MN; Li, W; Luo, P; Maddipati, KR; Seki, T; Wang, MH; Zhang, Y; Zheng, X	1
Alkayed, NJ; Anderson, VC; Borkar, RN; Cetas, JS; Dogan, A; Fairbanks, SL; Liu, JJ; Martini, RP; Nelson, JW; Raskin, JS; Siler, DA; Wang, RK; Ward, JP; Zuloaga, KL	1
Chen, H; Li, J; Liao, D; Wang, C; Wu, L; Yi, X	1
Liao, D; Lin, J; Yi, X; Zhang, B; Zhou, Q	1
Liao, D; Wang, C; Wu, L; Yi, X; Zhang, B	1
Han, Z; Lin, J; Liu, P; Yi, X; Zhou, Q	1
Lin, J; Wang, C; Yi, X; Zhou, Q	1
Almgren, P; Berglund, G; Engström, G; Fava, C; Hedblad, B; Lippi, G; Melander, O; Minuz, P; Montagnana, M; Rosberg, L	1
Cao, S; Harder, DR; Koehler, RC; Kwansa, H; Roman, RJ; Wang, LC	1
Eto, K; Marumo, T; Nabekura, J; Omura, T; Wake, H	1
Balzer, J; Bender, C; Crago, EA; Horowitz, M; Kuo, CW; Poloyac, SM; Sherwood, PR; Thampatty, BP	1
Carter, EL; Crafa, DA; Harder, DR; Kibler, KK; Koehler, RC; Kwansa, H; Martin, LJ; Roman, RJ; Yang, ZJ	1
Ago, Y; Baba, A; Chaki, S; Doi, H; Hashimoto, H; Kawasaki, T; Marumo, T; Matsuda, T; Mori, T; Nakazato, A; Onoe, H; Shirakami, K; Suzuki, M; Watanabe, Y	1
Cambj-Sapunar, L; Harder, DR; Roman, RJ; Yu, M	1
Kerr, ME; Poloyac, SM; Reynolds, RB; Yonas, H	1
Bies, RR; Graham, SH; Kochanek, PM; Poloyac, SM; Zhang, Y	1
Fukasawa, M; Hachiuma, K; Harder, DR; Koizumi, C; Minagawa, T; Miyata, N; Nakaike, S; Okuyama, S; Omura, T; Roman, RJ; Sakurai, T; Susumu, T; Tanaka, Y; Yoshida, S	1
Fukasawa, M; Horiuchi, N; Minagawa, T; Miyata, N; Nakaike, S; Omura, T; Tanaka, Y; Yoshida, S	1
Balazy, M; Bednar, MM; Falck, JR; Gross, CE	1

Reviews

1 review(s) available for 20-hydroxy-5,8,11,14-eicosatetraenoic acid and Cerebral Ischemia

Article	Year
Targeting vascular inflammation in ischemic stroke: Recent developments on novel immunomodulatory approaches. European journal of pharmacology, 2018, Aug-15, Volume: 833 Topics: Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Endothelial Cells; Genetic Therapy; Humans; Hydroxyeicosatetraenoic Acids; Hyperbaric Oxygenation; Immunomodulation; Inflammation; Macrophages; Microglia; MicroRNAs; Neuroprotective Agents; Oligonucleotides; Oxidative Stress; Signal Transduction; Stroke	2018

Article

Year

Targeting vascular inflammation in ischemic stroke: Recent developments on novel immunomodulatory approaches.

European journal of pharmacology, 2018, Aug-15, Volume: 833

Topics: Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Endothelial Cells; Genetic Therapy; Humans; Hydroxyeicosatetraenoic Acids; Hyperbaric Oxygenation; Immunomodulation; Inflammation; Macrophages; Microglia; MicroRNAs; Neuroprotective Agents; Oligonucleotides; Oxidative Stress; Signal Transduction; Stroke

2018

Other Studies

21 other study(ies) available for 20-hydroxy-5,8,11,14-eicosatetraenoic acid and Cerebral Ischemia

Article	Year
Astrocytic cytochrome P450 4A/20-hydroxyeicosatetraenoic acid contributes to angiogenesis in the experimental ischemic stroke. Brain research, 2019, 04-01, Volume: 1708 Topics: Angiogenesis Inducing Agents; Animals; Astrocytes; Brain Ischemia; Cell Proliferation; Cytochrome P-450 CYP4A; Disease Models, Animal; Endothelial Cells; Hydroxyeicosatetraenoic Acids; Male; Mice; Mice, Inbred C57BL; Microcirculation; Neovascularization, Pathologic; Stroke; Vascular Endothelial Growth Factor A	2019
Capillary pericytes regulate cerebral blood flow in health and disease. Nature, 2014, Apr-03, Volume: 508, Issue:7494 Topics: Animals; Arterioles; Blood-Brain Barrier; Brain Ischemia; Capillaries; Cell Death; Cerebellum; Cerebral Cortex; Cerebrovascular Circulation; Dinoprostone; Excitatory Amino Acid Antagonists; Female; Functional Neuroimaging; Glutamic Acid; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Pericytes; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Glutamate; Signal Transduction; Stroke; Vasoconstriction; Vasodilation	2014
Combined therapy with COX-2 inhibitor and 20-HETE inhibitor reduces colon tumor growth and the adverse effects of ischemic stroke associated with COX-2 inhibition. American journal of physiology. Regulatory, integrative and comparative physiology, 2014, Sep-15, Volume: 307, Issue:6 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Ischemia; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytochrome P-450 CYP4A; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Lactones; Male; Mice; Mice, Inbred C57BL; Rats; Stroke; Sulfones; Time Factors; Tumor Burden	2014
Protective role of p450 epoxyeicosanoids in subarachnoid hemorrhage. Neurocritical care, 2015, Volume: 22, Issue:2 Topics: 8,11,14-Eicosatrienoic Acid; Aged; Animals; Brain Ischemia; Disease Models, Animal; Female; Humans; Hydroxyeicosatetraenoic Acids; Male; Mice; Middle Aged; Neuroprotective Agents; Subarachnoid Hemorrhage	2015
CYP Genetic Variants, CYP Metabolite Levels, and Symptomatic Carotid Stenosis in Ischemic Stroke Patients. Journal of atherosclerosis and thrombosis, 2016, May-02, Volume: 23, Issue:5 Topics: Aged; Arachidonic Acids; Brain Ischemia; Carotid Arteries; Carotid Stenosis; Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Female; Genetic Variation; Genotype; Humans; Hydroxyeicosatetraenoic Acids; Male; Middle Aged; Polymorphism, Single Nucleotide; Risk; Stroke; Ultrasonography	2016
Interaction Between CYP4F2 rs2108622 and CPY4A11 rs9333025 Variants Is Significantly Correlated with Susceptibility to Ischemic Stroke and 20-Hydroxyeicosatetraenoic Acid Level. Genetic testing and molecular biomarkers, 2016, Volume: 20, Issue:5 Topics: Aged; Brain Ischemia; Case-Control Studies; Cytochrome P-450 CYP4A; Cytochrome P450 Family 4; Epistasis, Genetic; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Hydroxyeicosatetraenoic Acids; Male; Middle Aged; Polymorphism, Single Nucleotide; Stroke	2016
Interactions Among CYP2C8, EPHX2, and CYP4A11 Variants and CYP Plasma Metabolite Levels in Ischemic Stroke. Journal of atherosclerosis and thrombosis, 2016, Nov-01, Volume: 23, Issue:11 Topics: Aged; Biomarkers; Brain Ischemia; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP4A; Epoxide Hydrolases; Female; Follow-Up Studies; Genetic Variation; Genotype; Humans; Hydroxyeicosatetraenoic Acids; Male; Prognosis; Stroke	2016
20-Hydroxyeicosatetraenoic Acid as a Predictor of Neurological Deterioration in Acute Minor Ischemic Stroke. Stroke, 2016, Volume: 47, Issue:12 Topics: Brain Ischemia; Disease Progression; Humans; Hydroxyeicosatetraenoic Acids; Prognosis; Prospective Studies; Stroke	2016
CYP Genetic Variants, CYP Metabolite Levels, and Neurologic Deterioration in Acute Ischemic Stroke in Chinese Population. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2017, Volume: 26, Issue:5 Topics: Aged; Aged, 80 and over; Asian People; Biomarkers; Brain Ischemia; Chi-Square Distribution; China; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Eicosanoids; Epoxide Hydrolases; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Hydroxyeicosatetraenoic Acids; Male; Middle Aged; Nerve Degeneration; Odds Ratio; Phenotype; Polymorphism, Single Nucleotide; Prospective Studies; Risk Factors; Stroke; Time Factors	2017
The V433M variant of the CYP4F2 is associated with ischemic stroke in male Swedes beyond its effect on blood pressure. Hypertension (Dallas, Tex. : 1979), 2008, Volume: 52, Issue:2 Topics: Analysis of Variance; Anthropometry; Brain Ischemia; Cohort Studies; Cytochrome P-450 CYP4A; Female; Gene Expression Regulation; Genetic Predisposition to Disease; Genotype; Heterozygote; Humans; Hydroxyeicosatetraenoic Acids; Hypertension; Kaplan-Meier Estimate; Male; Middle Aged; Polymorphism, Genetic; Probability; Proportional Hazards Models; Sex Factors; Stroke	2008
Endothelin rather than 20-HETE contributes to loss of pial arteriolar dilation during focal cerebral ischemia with and without polymeric hemoglobin transfusion. American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:5 Topics: Amidines; Animals; Arterioles; Blood Substitutes; Blood Transfusion; Brain Ischemia; Endothelin A Receptor Antagonists; Endothelins; Hemoglobins; Hydroxyeicosatetraenoic Acids; Male; Models, Animal; Oligopeptides; Pia Mater; Polymers; Rats; Rats, Wistar; Regional Blood Flow; Vasodilation	2009
The inhibitor of 20-HETE synthesis, TS-011, improves cerebral microcirculatory autoregulation impaired by middle cerebral artery occlusion in mice. British journal of pharmacology, 2010, Volume: 161, Issue:6 Topics: Animals; Blood Flow Velocity; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Animal; Formamides; Homeostasis; Hydroxyeicosatetraenoic Acids; Infarction, Middle Cerebral Artery; Infusions, Intravenous; Male; Mice; Mice, Inbred C57BL; Microcirculation; Morpholines	2010
Cerebrospinal fluid 20-HETE is associated with delayed cerebral ischemia and poor outcomes after aneurysmal subarachnoid hemorrhage. Stroke, 2011, Volume: 42, Issue:7 Topics: Adolescent; Adult; Aged; Brain Ischemia; Cerebrovascular Circulation; Female; Humans; Hydroxyeicosatetraenoic Acids; Male; Microcirculation; Middle Aged; Neuropsychological Tests; Subarachnoid Hemorrhage; Treatment Outcome; Ultrasonography, Doppler	2011
Attenuation of neonatal ischemic brain damage using a 20-HETE synthesis inhibitor. Journal of neurochemistry, 2012, Volume: 121, Issue:1 Topics: Amidines; Animals; Animals, Newborn; Brain Ischemia; Hydroxyeicosatetraenoic Acids; Infusions, Intraventricular; Male; Swine	2012
Increase of 20-HETE synthase after brain ischemia in rats revealed by PET study with 11C-labeled 20-HETE synthase-specific inhibitor. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2012, Volume: 32, Issue:9 Topics: Animals; Autoradiography; Brain Ischemia; Carbon Radioisotopes; Cytochrome P-450 CYP4A; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Hydroxyeicosatetraenoic Acids; Imidazoles; Immunohistochemistry; Isotope Labeling; Longitudinal Studies; Mice; Mice, Inbred C57BL; Polymerase Chain Reaction; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Wistar; Tissue Distribution	2012
Contribution of 5-hydroxytryptamine1B receptors and 20-hydroxyeiscosatetraenoic acid to fall in cerebral blood flow after subarachnoid hemorrhage. Stroke, 2003, Volume: 34, Issue:5 Topics: Amidines; Animals; Blood; Brain Ischemia; Calcium Signaling; Cerebrospinal Fluid; Cerebrovascular Circulation; Cisterna Magna; Eicosanoic Acids; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Injections; Male; Middle Cerebral Artery; Muscle, Smooth, Vascular; Phospholipases A; Propanolamines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Subarachnoid Hemorrhage; Vascular Resistance; Vasoconstriction; Vasospasm, Intracranial	2003
Identification and quantification of the hydroxyeicosatetraenoic acids, 20-HETE and 12-HETE, in the cerebrospinal fluid after subarachnoid hemorrhage. Journal of neuroscience methods, 2005, Jun-15, Volume: 144, Issue:2 Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adult; Aged; Arachidonic Acid; Brain Ischemia; Cerebral Arteries; Cerebrospinal Fluid; Chromatography, High Pressure Liquid; Humans; Hydroxyeicosatetraenoic Acids; Mass Spectrometry; Middle Aged; Neurochemistry; Subarachnoid Hemorrhage; Time Factors; Vasospasm, Intracranial	2005
Protective effect of the 20-HETE inhibitor HET0016 on brain damage after temporary focal ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2006, Volume: 26, Issue:12 Topics: Amidines; Animals; Brain Injuries; Brain Ischemia; Cerebrovascular Circulation; Cytochrome P-450 Enzyme System; Hydroxyeicosatetraenoic Acids; Male; Microsomes; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stroke; Vasoconstriction	2006
Effect of a new inhibitor of the synthesis of 20-HETE on cerebral ischemia reperfusion injury. Stroke, 2006, Volume: 37, Issue:5 Topics: Animals; Brain Ischemia; Dose-Response Relationship, Drug; Formamides; Gas Chromatography-Mass Spectrometry; Haplorhini; Hydroxyeicosatetraenoic Acids; Male; Morpholines; Rats; Rats, Wistar; Reperfusion Injury	2006
Continuous inhibition of 20-HETE synthesis by TS-011 improves neurological and functional outcomes after transient focal cerebral ischemia in rats. Neuroscience research, 2007, Volume: 59, Issue:4 Topics: Animals; Brain; Brain Ischemia; Cerebral Arteries; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Drug Administration Schedule; Formamides; Hydroxyeicosatetraenoic Acids; Ischemic Attack, Transient; Morpholines; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Treatment Outcome; Up-Regulation; Vasodilation	2007
Antineutrophil strategies. Neurology, 1997, Volume: 49, Issue:5 Suppl 4 Topics: Aged; Aged, 80 and over; Brain Ischemia; Cell Adhesion; Cerebrovascular Disorders; Humans; Hydroxyeicosatetraenoic Acids; Leukocyte Count; Middle Aged; Neutrophil Activation; Neutrophils	1997