20-hydroxy-5,8,11,14-eicosatetraenoic acid has been researched along with Alloxan Diabetes in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Azar, S; Eid, AA; Eid, S; Haddad, M; Harb, F; Massry, MEL; Sauleau, EA | 1 |
| Alaeddine, LM; Azar, NS; Dia, B; Eid, AA; El Khoury, M; Hamza, M; Harb, F; Mogharbil, N; Noureldein, MH; Sabra, R | 1 |
| Ćosić, A; Drenjančević, I; Mihalj, M; Mišir, M; Novak, S; Renić, M; Vesel, M | 1 |
| Chen, R; Cheng, O; Ding, S; Huang, B; Huang, J; Jiang, Q; Qiu, H; Zhang, J; Zou, X | 1 |
| Elmarakby, AA; Katary, MM; Pye, C | 1 |
| Chang, HH; Inscho, EW; Luo, P; Seki, T; Wang, CY; Wang, MH; Zhang, J; Zhou, Y | 1 |
| Akhtar, S; Benter, IF; Dahly-Vernon, AJ; Dunn, KM; Roman, RJ; Yousif, MH | 1 |
| Benter, IF; Roman, RJ; Yousif, MH | 1 |
| Barbosa-Sicard, E; Bauersachs, J; Ertl, G; Fleming, I; Fraccarollo, D; Galuppo, P; Pfrang, J; Ruetten, H; Schäfer, A; Tas, P; Vogt, C; Widder, JD | 1 |
| Harris, NR; Leskova, W; Wang, Z; Yadav, AS | 1 |
| Chen, YJ; Quilley, J | 1 |
| Akhtar, S; Benter, IF; Canatan, H; Yousif, MH | 1 |
| Chen, YJ; Li, J; Quilley, J | 1 |
1 review(s) available for 20-hydroxy-5,8,11,14-eicosatetraenoic acid and Alloxan Diabetes
| Article | Year |
|---|---|
Meloxicam fails to augment the reno-protective effects of soluble epoxide hydrolase inhibition in streptozotocin-induced diabetic rats via increased 20-HETE levels.
Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Cytochrome P-450 Enzyme System; Cytoprotection; Diabetes Mellitus, Experimental; Drug Synergism; Enzyme Inhibitors; Epoxide Hydrolases; Gene Expression Regulation, Enzymologic; Hydroxyeicosatetraenoic Acids; Kidney; Male; Meloxicam; Rats; Rats, Sprague-Dawley; Solubility; Thiazines; Thiazoles | 2017 |
12 other study(ies) available for 20-hydroxy-5,8,11,14-eicosatetraenoic acid and Alloxan Diabetes
| Article | Year |
|---|---|
Activation of 20-HETE Synthase Triggers Oxidative Injury and Peripheral Nerve Damage in Type 2 Diabetic Mice.
Topics: AMP-Activated Protein Kinases; Animals; Cytochrome P-450 CYP4A; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Hydroxyeicosatetraenoic Acids; Metformin; Mice; Oxidative Stress; Peripheral Nerve Injuries; Peripheral Nerves; Reactive Oxygen Species | 2022 |
Pharmacological regulation of cytochrome P450 metabolites of arachidonic acid attenuates cardiac injury in diabetic rats.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Cardiomyopathies; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Hydroxyeicosatetraenoic Acids; Male; NADPH Oxidase 4; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Streptozocin | 2021 |
Hyperbaric oxygenation and 20-hydroxyeicosatetreanoic acid inhibition reduce stroke volume in female diabetic Sprague-Dawley rats.
Topics: Amidines; Animals; Aryl Hydrocarbon Hydroxylases; Brain; Combined Modality Therapy; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Cytochrome P450 Family 4; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Epoxide Hydrolases; Female; Gene Expression Regulation, Enzymologic; Hydroxyeicosatetraenoic Acids; Hyperbaric Oxygenation; Infarction, Middle Cerebral Artery; Neuroprotective Agents; Nitric Oxide Synthase Type III; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger; Steroid 16-alpha-Hydroxylase; Time Factors | 2017 |
Activation of 20-HETE/PPARs involved in reno-therapeutic effect of naringenin on diabetic nephropathy.
Topics: Animals; Cell Line; Cell Proliferation; Cytochrome P-450 CYP4A; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet, High-Fat; Female; Flavanones; Glucose; Hydroxyeicosatetraenoic Acids; Kidney; Mice; Peroxisome Proliferator-Activated Receptors; Rats; Streptozocin; Up-Regulation | 2019 |
Glomerular 20-HETE, EETs, and TGF-beta1 in diabetic nephropathy.
Topics: 8,11,14-Eicosatrienoic Acid; Amino Acids; Animals; Clofibrate; Cytochrome P-450 CYP4A; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Epoxide Hydrolases; Epoxy Compounds; Hydroxyeicosatetraenoic Acids; Hyperglycemia; Hyperlipidemias; Kidney; Kidney Glomerulus; Male; Polymerase Chain Reaction; Protein Isoforms; Proteinuria; Rats; Rats, Sprague-Dawley; Renal Circulation; Streptozocin; Transforming Growth Factor beta1 | 2009 |
Role of 20-hydroxyeicosatetraenoic acid in altering vascular reactivity in diabetes.
Topics: Amidines; Angiotensin II; Animals; Blood Glucose; Body Weight; Carbachol; Cytochrome P-450 CYP4A; Diabetes Mellitus, Experimental; Endothelin-1; Enzyme Inhibitors; Histamine; Hydroxyeicosatetraenoic Acids; Kidney; Male; Mesenteric Arteries; Microsomes; Nitroprusside; Norepinephrine; Perfusion; Rats; Rats, Wistar; Renal Artery; Triazoles; Vasoconstriction; Vasodilation | 2009 |
Cytochrome P450 metabolites of arachidonic acid play a role in the enhanced cardiac dysfunction in diabetic rats following ischaemic reperfusion injury.
Topics: 8,11,14-Eicosatrienoic Acid; Amidines; Animals; Arachidonic Acid; Blood Glucose; Body Weight; Coronary Circulation; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Epoxide Hydrolases; Glyburide; Heart; Hydroxyeicosatetraenoic Acids; Male; Microsomes; Myocardium; Rats; Rats, Wistar; Reperfusion Injury; Urea; Vascular Resistance; Ventricular Dysfunction, Left | 2009 |
Increased cytochrome P4502E1 expression and altered hydroxyeicosatetraenoic acid formation mediate diabetic vascular dysfunction: rescue by guanylyl-cyclase activation.
Topics: Animals; Aorta, Thoracic; Cytochrome P-450 CYP2E1; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Gene Expression Regulation, Enzymologic; Guanylate Cyclase; Humans; Hydroxyeicosatetraenoic Acids; MicroRNAs; Oligonucleotide Array Sequence Analysis; ortho-Aminobenzoates; Oxidative Stress; Rats; Reactive Oxygen Species; Sulfonamides; Superoxides; Up-Regulation; Vasodilation | 2010 |
Inhibition of 20-HETE attenuates diabetes-induced decreases in retinal hemodynamics.
Topics: Amidines; Animals; Blood Flow Velocity; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Erythrocytes; Hydroxyeicosatetraenoic Acids; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Regional Blood Flow; Retinal Vessels | 2011 |
Role of COX-2 in the enhanced vasoconstrictor effect of arachidonic acid in the diabetic rat kidney.
Topics: Animals; Arachidonic Acid; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Hydroxyeicosatetraenoic Acids; Isoenzymes; Kidney; Male; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Wistar; Vasoconstriction; Vasoconstrictor Agents | 2003 |
Inhibition of Ca2+/calmodulin-dependent protein kinase II, RAS-GTPase and 20-hydroxyeicosatetraenoic acid attenuates the development of diabetes-induced vascular dysfunction in the rat carotid artery.
Topics: Amidines; Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carotid Arteries; Carotid Artery Diseases; Diabetes Mellitus, Experimental; Hydroxyeicosatetraenoic Acids; Monomeric GTP-Binding Proteins; Organophosphonates; Protein Kinase Inhibitors; Rats; Rats, Wistar; Streptozocin; Sulfonamides; Triazoles; Vascular Diseases; Vasoconstriction; Vasodilation | 2005 |
Deficient renal 20-HETE release in the diabetic rat is not the result of oxidative stress.
Topics: Aldehyde Reductase; Animals; Antioxidants; Arachidonic Acid; Benzothiazoles; Cyclic N-Oxides; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP4A; Diabetes Mellitus, Experimental; Enzyme Induction; Enzyme Inhibitors; Fenofibrate; Hydroxyeicosatetraenoic Acids; Hypoglycemic Agents; Indomethacin; Insulin; Kidney; Male; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Perfusion; Phthalazines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Spin Labels; Tyrosine | 2008 |