20-alpha-dihydroprogesterone has been researched along with Breast Neoplasms in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cadieux-Pitre, HA; Welch, I; Wiebe, JP; Zhang, G | 1 |
| Beausoleil, M; Cialacu, V; Wiebe, JP; Zhang, G | 1 |
| Blair, IA; Byrns, MC; Duan, L; Lee, SH; Penning, TM | 1 |
| Franke, HR; Vermes, I | 1 |
| Pawlak, KJ; Wiebe, JP; Zhang, G | 1 |
| de Levin, RW; Levin, E; Puig, OR | 1 |
| Weiler, PJ; Wiebe, JP | 1 |
| Burczynski, ME; Jez, JM; Lin, HK; Ma, H; Moore, M; Palackal, N; Penning, TM; Ratnam, K | 1 |
| Kapur, MM; Laumas, KR; Verma, U | 1 |
| Milgrom, E; Pichon, MF | 1 |
10 other study(ies) available for 20-alpha-dihydroprogesterone and Breast Neoplasms
| Article | Year |
|---|---|
Progesterone metabolites regulate induction, growth, and suppression of estrogen- and progesterone receptor-negative human breast cell tumors.
Topics: 20-alpha-Dihydroprogesterone; 5-alpha-Dihydroprogesterone; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Mice, Inbred NOD; Mice, SCID; Receptors, Estrogen; Receptors, Progesterone; Tissue Distribution; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Opposing actions of the progesterone metabolites, 5alpha-dihydroprogesterone (5alphaP) and 3alpha-dihydroprogesterone (3alphaHP) on mitosis, apoptosis, and expression of Bcl-2, Bax and p21 in human breast cell lines.
Topics: 20-alpha-Dihydroprogesterone; 5-alpha-Dihydroprogesterone; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Female; Gene Expression Regulation, Neoplastic; Humans; Mammary Glands, Human; Mitosis; Progesterone; Proto-Oncogene Proteins c-bcl-2 | 2010 |
Aldo-keto reductase 1C3 expression in MCF-7 cells reveals roles in steroid hormone and prostaglandin metabolism that may explain its over-expression in breast cancer.
Topics: 20-alpha-Dihydroprogesterone; 3-Hydroxysteroid Dehydrogenases; 5-alpha-Dihydroprogesterone; Aldo-Keto Reductase Family 1 Member C3; Androstenedione; Androsterone; Biocatalysis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Dinoprost; Estradiol; Estrone; Etiocholanolone; Female; Gene Expression Regulation, Neoplastic; Gonadal Steroid Hormones; Humans; Hydroxyprostaglandin Dehydrogenases; Ketosteroids; Kinetics; Progesterone; Prostaglandin D2; Prostaglandins; Recombinant Proteins; Testosterone; Transfection; Up-Regulation | 2010 |
The effect of continuous combined 17beta-oestradiol and dihydrodydrogesterone on apoptotic cell death and proliferation of human breast cancer cells in vitro.
Topics: 20-alpha-Dihydroprogesterone; Apoptosis; Breast Neoplasms; Cell Division; Drug Combinations; Dydrogesterone; Estradiol; Female; Humans; Tumor Cells, Cultured | 2002 |
Membrane 5alpha-pregnane-3,20-dione (5alphaP) receptors in MCF-7 and MCF-10A breast cancer cells are up-regulated by estradiol and 5alphaP and down-regulated by the progesterone metabolites, 3alpha-dihydroprogesterone and 20alpha-dihydroprogesterone, with
Topics: 20-alpha-Dihydroprogesterone; 5-alpha-Dihydroprogesterone; Antineoplastic Agents; Breast Neoplasms; Cell Adhesion; Cell Fractionation; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cycloheximide; Dactinomycin; Down-Regulation; Estradiol; Female; Humans; Progesterone; Receptors, Estradiol; Receptors, Progesterone; Up-Regulation | 2005 |
Increased risk for cancer of the breast due to previous medication.
Topics: 20-alpha-Dihydroprogesterone; Adult; Aged; Amitriptyline; Amphetamines; Breast Neoplasms; Cimetidine; Contraceptive Agents; Estradiol; Female; Humans; Methyldopa; Middle Aged; Phenothiazines; Prolactin; Psychotropic Drugs; Quinestrol; Risk; Time Factors | 1984 |
Plasma membrane receptors for the cancer-regulating progesterone metabolites, 5alpha-pregnane-3,20-dione and 3alpha-hydroxy-4-pregnen-20-one in MCF-7 breast cancer cells.
Topics: 20-alpha-Dihydroprogesterone; 5-alpha-Dihydroprogesterone; Binding Sites; Breast Neoplasms; Cell Fractionation; Cell Membrane; Cell Nucleus; Cytosol; Estradiol; Estrogen Antagonists; Female; Humans; Kinetics; Pregnanediones; Progesterone; Receptors, Cell Surface; Substrate Specificity; Thermodynamics; Tumor Cells, Cultured | 2000 |
Structure-function aspects and inhibitor design of type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3).
Topics: 17-Hydroxysteroid Dehydrogenases; 20-alpha-Dihydroprogesterone; 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; Animals; Binding Sites; Breast Neoplasms; Cloning, Molecular; Enzyme Inhibitors; Escherichia coli; Estradiol; Estrone; Female; Gene Expression; Gene Library; Humans; Isoenzymes; Liver; Male; Mammary Glands, Animal; Mutagenesis, Site-Directed; Progesterone; Prostate; Prostatic Neoplasms; Rats; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Structure-Activity Relationship; Tissue Distribution; Uterus | 2001 |
Characterization of progesterone receptors and metabolism of progesterone in the normal and cancerous human mammary gland.
Topics: 20-alpha-Dihydroprogesterone; Adult; Binding Sites; Binding, Competitive; Breast; Breast Neoplasms; Cell Nucleus; Cytosol; Female; Humans; Microsomes; Middle Aged; Mitochondria; Molecular Weight; Progesterone; Receptors, Progesterone | 1978 |
Characterization and assay of progesterone receptor in human mammary carcinoma.
Topics: 20-alpha-Dihydroprogesterone; Adult; Aged; Breast Neoplasms; Centrifugation, Density Gradient; Corticosterone; Cytosol; DNA; Estradiol; Estrogens; Female; Glycerol; Humans; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Middle Aged; Pregnanediones; Progesterone; Progesterone Congeners; Receptors, Estrogen; Receptors, Progesterone; Testosterone; Transcortin | 1977 |