2-thio-6-azathymine and Malaria

2-thio-6-azathymine has been researched along with Malaria* in 1 studies

Other Studies

1 other study(ies) available for 2-thio-6-azathymine and Malaria

ArticleYear
Antimalarials. 3. 1,2,4-Triazines.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:6

    The syntheses of a number of substituted 1,2,4-triazines as potential antimalarials are described. The structural requirements for antimalarial activity are discussed with reference to the substituents of a phenyl group in the 6 position and amino groups at the 3 and 5 positions. Of the compounds tested, 2,5, and 7 produced cures in mice infected with plasmodium berghei. Compounds 2(3,5-diamino-6-(4-trifluoromethylphenyl)-1,2,4-triazine),3,5,8,12,and 37 produced cures in chicks infected with Plasmodium gallinaceum.

    Topics: Animals; Antimalarials; Chickens; Malaria; Malaria, Avian; Mice; Plasmodium berghei; Structure-Activity Relationship; Triazines

1976