Compounds > 2-propanol
Page last updated: 2024-10-29

2-propanol and Neurofibromatosis 1

2-propanol has been researched along with Neurofibromatosis 1 in 50 studies

2-Propanol: An isomer of 1-PROPANOL. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
propan-2-ol : A secondary alcohol that is propane in which one of the hydrogens attached to the central carbon is substituted by a hydroxy group.

Neurofibromatosis 1: An autosomal dominant inherited disorder (with a high frequency of spontaneous mutations) that features developmental changes in the nervous system, muscles, bones, and skin, most notably in tissue derived from the embryonic NEURAL CREST. Multiple hyperpigmented skin lesions and subcutaneous tumors are the hallmark of this disease. Peripheral and central nervous system neoplasms occur frequently, especially OPTIC NERVE GLIOMA and NEUROFIBROSARCOMA. NF1 is caused by mutations which inactivate the NF1 gene (GENES, NEUROFIBROMATOSIS 1) on chromosome 17q. The incidence of learning disabilities is also elevated in this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1014-18) There is overlap of clinical features with NOONAN SYNDROME in a syndrome called neurofibromatosis-Noonan syndrome. Both the PTPN11 and NF1 gene products are involved in the SIGNAL TRANSDUCTION pathway of Ras (RAS PROTEINS).

Research Excerpts

ExcerptRelevanceReference
"Von Recklinghausen disease or neurofibromatosis type I (NF1) is the most common phacomatosis."1.72[Lisch nodules: an ophthalmic marker of neurofibromatosis type 1]. ( Bouirig, K; Cherkaoui, LO, 2022)
"Uveal melanoma is the most common primary intraocular malignancy in adults."1.62Neurofibromatosis type 1 and melanoma of the iris arising from a dysplastic nevus: A rare yet casual association? ( Albano, V; Alessio, G; Falcone, V; Guerriero, S; Lastella, P; Piscitelli, D; Resta, N; Stella, A, 2021)
"Ocular manifestations such as coloboma of the iris, the retina and the choroid have not been reported so far."1.31[LEOPARD syndrome with iris-retina-choroid coloboma. Discordant findings in monozygotic twins (MIM # 151 100)]. ( Boergen, KP; Haritoglou, C; Kalpadakis, P; Meitinger, T; Rudolph, G, 2001)
"Iris nodules in neurofibromatosis I have become an important tool in the differential diagnosis of phakomatoses."1.30[Lisch nodules. Markers of neurofibromatosis 1 and immunohistochemical references for neuroectodermal differentiation]. ( Junk, AK; Kampik, A; Lukacs, A; Plewig, G; Schirren, CG; Stefani, FH, 1997)
"Bilateral acoustic neuromas, frontal meningiomas and a brain stem schwannoma were found on clinical and CT scan examinations and were histologically confirmed after surgery."1.28Type 2 neurofibromatosis with Lisch nodules. ( Ameriso, S; Arberas, C; Garretto, NS; Molina, HA; Monteverde, D; Salvat, J; Sica, RE, 1989)

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-199030 (60.00)18.7374
1990's5 (10.00)18.2507
2000's6 (12.00)29.6817
2010's3 (6.00)24.3611
2020's6 (12.00)2.80

Authors

AuthorsStudies
Carnevale, JA1
Goldberg, JL1
Schwartz, T1
Anguita, R1
Veas, R1
Thananjeyan, AL1
Karaconji, T1
Flaherty, M1
Zagora, S1
Jamieson, RV1
Grigg, JRB1
Bouirig, K1
Cherkaoui, LO1
Alessio, G1
Guerriero, S1
Albano, V1
Piscitelli, D1
Falcone, V1
Lastella, P1
Resta, N1
Stella, A1
Sanjay, S1
Mahendradas, P1
López-Herrero, F1
Rueda-Rueda, T1
Sánchez-Vicente, JL1
Seva-Silva, N1
Gómez Moyano, E1
Martínez Pilar, L1
Rodriguez Calvo de Mora, M1
Herrero Garcia, MV1
Francia, A1
Godoy Diaz, DJ1
Vera Casaño, A1
Liang, C1
Schaffer, JV1
Boley, S1
Sloan, JL1
Pemov, A1
Stewart, DR1
UNGER, K1
Mulholland, CP1
Rootman, J1
Lyons, CJ1
PIETRUSCHKA, G1
LOWENSTEIN, O1
LOEWENFELD, IE1
de HAAS, E1
HOUTSMULLER, AJ1
WOLTER, JR1
BUTLER, RG1
Richetta, A1
Giustini, S1
Recupero, SM1
Pezza, M1
Carlomagno, V1
Amoruso, G1
Calvieri, S1
Wood, TD1
Egan, RA1
Grossman, H1
Merten, DF1
Kirks, DR1
Ritch, R1
Forbes, M1
Hetherington, J1
Harrison, R1
Podos, SM1
Ender, A1
Weickert, H1
Braun, HS1
Franz, U1
Ender, I1
Lillquist, K1
Warburg, M1
Andersen, SR1
Hägerstrand, I1
Woog, JJ1
Albert, DM1
Solt, LC1
Hu, DN1
Wang, WJ1
Perry, HD1
Font, RL2
Beauchamp, GR1
Ragge, NK1
Acheson, J1
Murphree, AL1
Lukacs, A1
Junk, AK1
Stefani, FH1
Kampik, A1
Schirren, CG1
Plewig, G1
Rudolph, G1
Haritoglou, C1
Kalpadakis, P1
Boergen, KP1
Meitinger, T1
Vabres, P1
Bonneau, D1
Larrègue, M1
Wiznia, RA1
Freedman, JK1
Mancini, AD1
Shields, JA1
Knudson, AG1
Meadows, AT1
Bartkowska-Orlowska, M1
Orlowski, WJ1
Przybyl-Ereńska, K1
Janotka, H1
Czechowa, M1
Matusik, J1
Shields, MB1
Campbell, DG1
Simmons, RJ1
Hutchinson, BT1
Green, JE1
Baird, AM1
Hinrichs, SH1
Klintworth, GK1
Jay, G1
Williamson, TH1
Garner, A1
Moore, AT1
Garretto, NS1
Ameriso, S1
Molina, HA1
Arberas, C1
Salvat, J1
Monteverde, D1
Sica, RE1
Zehavi, C1
Romano, A1
Goodman, RM1
Pearson-Webb, MA1
Kaiser-Kupfer, MI1
Eldridge, R1
Huson, S1
Jones, D1
Beck, L1
Béchetoille, A1
Ebran, JM1
Bigorgne, J1
François, J1
Hanssens, M1
Evens, L1
Bradley, WG1
Richardson, J1
Frew, IJ1
Ferry, AP1
Ufermann, K1
Grant, WM1
Walton, DS1
Verbeck, B1
Nordmann, J2
Brini, A2
Philippides, D1
Focosi, F1
Salvaggio, E1

Reviews

2 reviews available for 2-propanol and Neurofibromatosis 1

ArticleYear
Congenital and inheritable diseases associated with tumors and generalized malignancies--an imaging approach.
    Critical reviews in diagnostic imaging, 1983, Volume: 19, Issue:1

    Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Basal Cell Nevus Syndrome; Beckwith-Wiedemann Synd

1983
The phakomatoses.
    International ophthalmology clinics, 1972,Spring, Volume: 12, Issue:1

    Topics: Angiomatosis; Anterior Chamber; Arteriovenous Fistula; Ataxia Telangiectasia; Brain Neoplasms; Choro

1972

Other Studies

48 other studies available for 2-propanol and Neurofibromatosis 1

ArticleYear
Seizure in Patient with Neurofibromatosis and Amygdala Low-Grade Glioma.
    World neurosurgery, 2022, Volume: 157

    Topics: Adult; Amygdala; Bipolar Disorder; Brain Neoplasms; Electroencephalography; Epilepsy, Temporal Lobe;

2022
Lisch Nodules.
    The New England journal of medicine, 2022, Feb-03, Volume: 386, Issue:5

    Topics: Adult; Hamartoma; Humans; Iris; Iris Diseases; Male; Neurofibromatosis 1

2022
A case of neurofibromatosis type 1 and unilateral glaucoma with ectropion uveae.
    Ophthalmic genetics, 2022, Volume: 43, Issue:5

    Topics: Ectropion; Glaucoma; Humans; Iris; Iris Diseases; Neurofibromatosis 1

2022
[Lisch nodules: an ophthalmic marker of neurofibromatosis type 1].
    The Pan African medical journal, 2022, Volume: 42

    Topics: Female; Hamartoma; Humans; Iris; Iris Neoplasms; Middle Aged; Neurofibromatoses; Neurofibromatosis 1

2022
Neurofibromatosis type 1 and melanoma of the iris arising from a dysplastic nevus: A rare yet casual association?
    European journal of ophthalmology, 2021, Volume: 31, Issue:3

    Topics: Dysplastic Nevus Syndrome; Humans; Iris; Male; Melanoma; Middle Aged; Neurofibromatosis 1; Skin Neop

2021
Commentary: Iris nodules in infants and children- A challenging dilemma.
    Indian journal of ophthalmology, 2020, Volume: 68, Issue:9

    Topics: Child; Humans; Infant; Iris; Neurofibromatosis 1; Polymerase Chain Reaction; Xanthogranuloma, Juveni

2020
Iris mammillations in a patient with type 1 neurofibromatosis.
    Archivos de la Sociedad Espanola de Oftalmologia, 2019, Volume: 94, Issue:2

    Topics: Adolescent; Humans; Hyperpigmentation; Iris; Male; Neurofibromatosis 1

2019
Using dermoscopy to assess diagnostic criteria of neurofibromatosis.
    Journal of the American Academy of Dermatology, 2015, Volume: 73, Issue:1

    Topics: Adult; Dermoscopy; Female; Humans; Iris; Neurofibromatosis 1

2015
Mosaic neurofibromatosis type 1.
    Dermatology online journal, 2008, May-15, Volume: 14, Issue:5

    Topics: Adult; Diagnosis, Differential; Humans; Iris; Male; Neurofibromatosis 1; Skin; Skin Neoplasms

2008
A quantitative assessment of the burden and distribution of Lisch nodules in adults with neurofibromatosis type 1.
    Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:11

    Topics: Adolescent; Adult; Aged; Eye Color; Female; Genes, Neurofibromatosis 1; Genotype; Hamartoma; Humans;

2009
Neurofibromatosis iridis (Recklinghausen's disease).
    Archives of ophthalmology (Chicago, Ill. : 1929), 1947, Volume: 38, Issue:5

    Topics: Iris; Iris Plant; Neurofibromatoses; Neurofibromatosis 1

1947
Primary iris neovascularization in neurofibromatosis type 1.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2010, Volume: 30, Issue:4

    Topics: Adolescent; Amaurosis Fugax; Humans; Iris; Iris Diseases; Male; Neovascularization, Pathologic; Neur

2010
[Iris alterations in Recklinghausen's disease].
    Klinische Monatsblatter fur Augenheilkunde und fur augenarztliche Fortbildung, 1952, Volume: 121, Issue:6

    Topics: Humans; Iris; Neurofibromatoses; Neurofibromatosis 1

1952
Effect of physostigmine and pilocarpine on iris spincter of normal man; is it competitive or additive? Pupillographic studies.
    A.M.A. archives of ophthalmology, 1953, Volume: 50, Issue:3

    Topics: Diagnostic Techniques, Ophthalmological; Humans; Iris; Male; Neurofibromatoses; Neurofibromatosis 1;

1953
[A patient with Fuch's heterochromia and Recklinghausen's disease].
    Nederlands tijdschrift voor geneeskunde, 1962, Sep-15, Volume: 106

    Topics: Eye Abnormalities; Humans; Iris; Neurofibromatosis 1

1962
PIGMENT SPOTS OF THE IRIS AND ECTROPION UVEAE.
    American journal of ophthalmology, 1963, Volume: 56

    Topics: Ectropion; Eye Neoplasms; Glaucoma; Humans; Iris; Iris Diseases; Neurofibromatoses; Neurofibromatosi

1963
Lisch nodules of the iris in neurofibromatosis type 1.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2004, Volume: 18, Issue:3

    Topics: Biopsy, Needle; Female; Humans; Immunohistochemistry; Iris; Iris Neoplasms; Mast Cells; Middle Aged;

2004
Inferior predilection of Lisch nodules with ptosis.
    Neurology, 2005, Apr-26, Volume: 64, Issue:8

    Topics: Blepharoptosis; Environmental Exposure; Humans; Iris; Iris Diseases; Light; Male; Neurofibromatosis

2005
Congenital ectropion uveae with glaucoma.
    Ophthalmology, 1984, Volume: 91, Issue:4

    Topics: Abnormalities, Multiple; Adolescent; Adult; Child; Diagnosis, Differential; Ectropion; Eye Neoplasms

1984
[Family studies in Recklinghausen's neurofibromatosis--a clinical study].
    Beitrage zur Orthopadie und Traumatologie, 1984, Volume: 31, Issue:6

    Topics: Adolescent; Adult; Child; Female; Humans; Iris; Male; Neurofibromatosis 1; Scoliosis

1984
Colobomata of the iris, ciliary body and choroid in an infant with oesophago-tracheal fistula and congenital heart defects. An unknown malformation complex.
    Acta paediatrica Scandinavica, 1980, Volume: 69, Issue:3

    Topics: Abnormalities, Multiple; Choroid; Chromosome Inversion; Chromosomes, Human, 6-12 and X; Ciliary Body

1980
Neurofibromatosis of the eyelid and orbit.
    International ophthalmology clinics, 1982,Fall, Volume: 22, Issue:3

    Topics: Blepharoptosis; China; Conjunctiva; Eyelid Neoplasms; Humans; Infant; Iris; Iris Diseases; Male; Mas

1982
Iris nodules in von Recklinghausen's Neurofibromatosis. Electron microscopic confirmation of their melanocytic origin.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1982, Volume: 100, Issue:10

    Topics: Aged; Hamartoma; Humans; Iris; Male; Melanocytes; Microscopy, Electron; Neurofibromatosis 1; Uveal N

1982
Neurofibromatosis type 1 in children.
    Transactions of the American Ophthalmological Society, 1995, Volume: 93

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Female; Humans; Incidence; Infant; Iris; Iris Neop

1995
Iris mammillations: significance and associations.
    Eye (London, England), 1996, Volume: 10 ( Pt 1)

    Topics: Adult; Child; Child, Preschool; Female; Humans; Iris; Iris Diseases; Iris Neoplasms; Male; Melanosis

1996
[Lisch nodules. Markers of neurofibromatosis 1 and immunohistochemical references for neuroectodermal differentiation].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1997, Volume: 48, Issue:1

    Topics: Diagnosis, Differential; Genetic Counseling; Genetic Markers; Humans; Immunoenzyme Techniques; Iris;

1997
[LEOPARD syndrome with iris-retina-choroid coloboma. Discordant findings in monozygotic twins (MIM # 151 100)].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2001, Volume: 98, Issue:11

    Topics: Adult; Child; Choroid; Coloboma; Diseases in Twins; Female; Humans; Hypertelorism; Iris; Male; Neuro

2001
Absence of Lisch nodules in sporadic neurofibromatosis type 1 may reflect somatic mosaicism.
    Archives of dermatology, 2002, Volume: 138, Issue:6

    Topics: Humans; Iris; Iris Neoplasms; Mosaicism; Mutation; Neurofibromatosis 1; Sensitivity and Specificity;

2002
Malignant melanoma of the choroid in neurofibromatosis.
    American journal of ophthalmology, 1978, Volume: 86, Issue:5

    Topics: Choroid Neoplasms; Eye Neoplasms; Female; Hamartoma; Humans; Iris; Melanoma; Middle Aged; Neoplasms,

1978
Developmental genetics of neuroblastoma.
    Journal of the National Cancer Institute, 1976, Volume: 57, Issue:3

    Topics: Carcinoma in Situ; Child; Child, Preschool; Congenital Abnormalities; Demography; Female; Ganglia, A

1976
[The iris in von Recklinghausen's disease (author's transl)].
    Klinika oczna, 1977, Volume: 47, Issue:10

    Topics: Adult; Eye Neoplasms; Eyelid Neoplasms; Female; Humans; Iris; Male; Neurofibromatosis 1

1977
[Iris changes in Recklinghausen's disease].
    Klinika oczna, 1975, Volume: 45, Issue:4

    Topics: Adult; Cornea; Eye Diseases; Female; Humans; Iris; Neurofibromatosis 1

1975
Iris nodules in essential iris atrophy.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1976, Volume: 94, Issue:3

    Topics: Adult; Atrophy; Cornea; Diagnosis, Differential; Eye Neoplasms; Female; Glaucoma; Granuloma; Humans;

1976
Adrenal medullary tumors and iris proliferation in a transgenic mouse model of neurofibromatosis.
    The American journal of pathology, 1992, Volume: 140, Issue:6

    Topics: Adrenal Gland Neoplasms; Adrenal Medulla; Animals; Cell Division; Gene Products, tax; Genes, pX; Imm

1992
Structure of Lisch nodules in neurofibromatosis type 1.
    Ophthalmic paediatrics and genetics, 1991, Volume: 12, Issue:1

    Topics: Humans; Infant; Iris; Iris Neoplasms; Male; Neurofibromatosis 1; Nevus, Pigmented

1991
Type 2 neurofibromatosis with Lisch nodules.
    Neurofibromatosis, 1989, Volume: 2, Issue:5-6

    Topics: Adolescent; Brain Neoplasms; Female; Humans; Iris; Karyotyping; Meningioma; Neurofibromatosis 1; Neu

1989
Iris (Lisch) nodules in neurofibromatosis.
    Clinical genetics, 1986, Volume: 29, Issue:1

    Topics: Adolescent; Adult; Child; Child, Preschool; Eye Color; Humans; Iris; Middle Aged; Neurofibromatosis

1986
Eye findings in bilateral acoustic (central) neurofibromatosis: association with presenile lens opacities and cataracts but absence of Lisch nodules.
    The New England journal of medicine, 1986, Dec-11, Volume: 315, Issue:24

    Topics: Adolescent; Adult; Cataract; Cranial Nerve Neoplasms; Humans; Iris; Middle Aged; Neurofibromatosis 1

1986
Ophthalmic manifestations of neurofibromatosis.
    The British journal of ophthalmology, 1987, Volume: 71, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Female; Fluorescein Angiography

1987
[Congenital ectropion of the iris epithelium and glaucoma].
    Journal francais d'ophtalmologie, 1985, Volume: 8, Issue:8-9

    Topics: Anterior Chamber; Blepharoptosis; Child; Ectropion; Eyelid Neoplasms; Facial Bones; Glaucoma; Humans

1985
[Melanic ganglioneuroma of the choroid].
    Bulletin de la Societe belge d'ophtalmologie, 1972, Volume: 162

    Topics: Anterior Chamber; Cataract; Choroid Neoplasms; Cornea; Ganglioneuroma; Glaucoma; Humans; Iris; Male;

1972
The familial association of neurofibromatosis, peroneal muscular atrophy, congenital deafness, partial albinism, and Axenfeld's defect.
    Brain : a journal of neurology, 1974, Volume: 97, Issue:3

    Topics: Adult; Albinism; Congenital Abnormalities; Corneal Opacity; Deafness; Electromyography; Female; Fund

1974
[Bilateral ocular involvement in Recklinghausen's neurofibromatosis].
    Klinische Monatsblatter fur Augenheilkunde, 1972, Volume: 161, Issue:3

    Topics: Adult; Eye Neoplasms; Female; Humans; Iris; Neurofibromatosis 1; Optic Atrophy; Optic Nerve; Orbit;

1972
Distinctive gonioscopic findings in glaucoma due to neurofibromatosis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1968, Volume: 79, Issue:2

    Topics: Adult; Child; Child, Preschool; Eye Manifestations; Female; Glaucoma; Gonioscopy; Humans; Iris; Male

1968
[Ocular involvement in von Recklinghausen's neurofibromatosis].
    Klinische Monatsblatter fur Augenheilkunde, 1969, Volume: 155, Issue:5

    Topics: Adult; Child, Preschool; Diagnosis, Differential; Exophthalmos; Eye Neoplasms; Eyelids; Follow-Up St

1969
[Optic nerve glioma and iris nevus (von Recklinghausen's disease)].
    Bulletin des societes d'ophtalmologie de France, 1970, Volume: 70, Issue:1

    Topics: Glioma; Humans; Infant; Iris; Male; Neurofibromatosis 1; Nevus, Pigmented; Optic Nerve

1970
Von Recklinghausen's disease and melanoma of the uvea.
    The British journal of ophthalmology, 1970, Volume: 54, Issue:10

    Topics: Child; Eye Neoplasms; Humans; Infant; Iris; Male; Melanocytes; Melanoma; Neurofibromatosis 1; Optic

1970
[Clinical note on the iris manifestations of Recklinghausen's disease].
    Bollettino d'oculistica, 1970, Volume: 49, Issue:9

    Topics: Brain Neoplasms; Child; Eye Manifestations; Female; Head and Neck Neoplasms; Humans; Iris; Kyphosis;

1970