2-propanol has been researched along with Muscle Contraction in 236 studies
2-Propanol: An isomer of 1-PROPANOL. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
propan-2-ol : A secondary alcohol that is propane in which one of the hydrogens attached to the central carbon is substituted by a hydroxy group.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the mechanism of intraoperative floppy-iris syndrome (IFIS) by examining the binding affinity of tamsulosin and silodosin to α-receptors and melanin pigment using control and α(2)-blocker chronically administered in rabbit models." | 7.78 | Effects of tamsulosin and silodosin on isolated albino and pigmented rabbit iris dilators: possible mechanism of intraoperative floppy-iris syndrome. ( Goseki, T; Ishikawa, H; Mashimo, K; Nemoto, N; Ogasawara, S; Shimizu, K; Taguchi, Y; Yago, K, 2012) |
| "Instillation of pilocarpine-induced a miosis in a rabbit." | 7.68 | Inhibitory effect of pilocarpine on norepinephrine release from electrically stimulated iris dilator muscles of rabbits as a most possible mechanism of pilocarpine-induced miosis. ( Kokubu, N; Shiraishi, K; Takayanagi, I, 1993) |
| "Sympathetic denervation of the iris muscle produces increases in both the breakdown of phosphatidylinositol 4,5-bisphosphate (PIP2) and in muscle contraction in response to norepinephrine (NE)." | 7.67 | Surgical sympathetic denervation increases alpha 1-adrenoceptor-mediated accumulation of myo-inositol trisphosphate and muscle contraction in rabbit iris dilator smooth muscle. ( Abdel-Latif, AA; Akhtar, RA, 1986) |
| "To determine the mechanism of intraoperative floppy-iris syndrome (IFIS) by examining the binding affinity of tamsulosin and silodosin to α-receptors and melanin pigment using control and α(2)-blocker chronically administered in rabbit models." | 3.78 | Effects of tamsulosin and silodosin on isolated albino and pigmented rabbit iris dilators: possible mechanism of intraoperative floppy-iris syndrome. ( Goseki, T; Ishikawa, H; Mashimo, K; Nemoto, N; Ogasawara, S; Shimizu, K; Taguchi, Y; Yago, K, 2012) |
| "The effects of the ocular hypotensive agents prostaglandin F(2alpha) (PGF(2alpha)) and its analog latanoprost on intraocular pressure (IOP) in both animals and human have been investigated extensively in the last two decades." | 3.72 | Effects of prostaglandin F2alpha and latanoprost on phosphoinositide turnover, myosin light chain phosphorylation and contraction in cat iris sphincter. ( Abdel-Latif, AA; Ansari, HR; Davis, AM; Kaddour-Djebbar, I, 2003) |
| " In vitro studies demonstrated that 53 is a potent functional antagonist of the hNK-3 receptor (reversal of senktide-induced contractions in rabbit isolated iris sphincter muscles and reversal of NKB-induced Ca2+ mobilization in CHO cells stably expressing the hNK-3 receptor), while in vivo this compound showed oral and intravenous activity in NK-3 receptor-driven models (senktide-induced behavioral responses in mice and senktide-induced miosis in rabbits)." | 3.70 | Discovery of a novel class of selective non-peptide antagonists for the human neurokinin-3 receptor. 2. Identification of (S)-N-(1-phenylpropyl)-3-hydroxy-2-phenylquinoline-4-carboxamide (SB 223412). ( Cavagnera, S; Farina, C; Foley, JJ; Giardina, GA; Graziani, D; Grugni, M; Hay, DW; Luttmann, M; Medhurst, AD; Raveglia, LF; Rigolio, R; Sarau, HM; Schmidt, DB; Vecchietti, V, 1999) |
| "Sodium nitroprusside inhibited carbachol-induced contractions of the iris sphincter muscle in a concentration-dependent manner but had no effect on neurokinin A-induced muscle contractions." | 3.69 | Nitric oxide-sensitive and -insensitive contractions of the isolated rabbit iris sphincter muscle. ( Chuman, H; Chuman, T; Nao-i, N; Sawada, A; Wada, A; Yamamoto, R, 1996) |
| "Instillation of pilocarpine-induced a miosis in a rabbit." | 3.68 | Inhibitory effect of pilocarpine on norepinephrine release from electrically stimulated iris dilator muscles of rabbits as a most possible mechanism of pilocarpine-induced miosis. ( Kokubu, N; Shiraishi, K; Takayanagi, I, 1993) |
| "The effect of a cyclic GMP phosphodiesterase inhibitor, M & B 22948, on carbachol-induced phosphatidylinositol 4,5-bis-phosphate (PIP2) breakdown and phosphatidic acid labeling, 1,4,5-inositol trisphosphate (IP3) accumulation and muscle contraction was studied in bovine iris sphincter smooth muscle." | 3.68 | The effect of M & B 22948 on carbachol-induced inositol trisphosphate accumulation and contraction in iris sphincter smooth muscle. ( Abdel-Latif, AA; Akhtar, RA, 1991) |
| "We have investigated the interactions between the cAMP and inositol 1,4,5-trisphosphate (IP3)-Ca2+ signalling systems in the bovine iris sphincter by measuring the effects of beta-adrenergic and cholinergic muscarinic agonists and antagonists on cAMP formation, IP3 accumulation and muscle contraction-relaxation." | 3.67 | Activation of beta-adrenergic receptors causes stimulation of cyclic AMP, inhibition of inositol trisphosphate, and relaxation of bovine iris sphincter smooth muscle. Biochemical and functional interactions between the cyclic AMP and calcium signalling sy ( Abdel-Latif, AA; Akhtar, RA; Tachado, SD, 1989) |
| "Sympathetic denervation of the iris muscle produces increases in both the breakdown of phosphatidylinositol 4,5-bisphosphate (PIP2) and in muscle contraction in response to norepinephrine (NE)." | 3.67 | Surgical sympathetic denervation increases alpha 1-adrenoceptor-mediated accumulation of myo-inositol trisphosphate and muscle contraction in rabbit iris dilator smooth muscle. ( Abdel-Latif, AA; Akhtar, RA, 1986) |
| "1 microM Ca++; and phorbol 12,13-dibutyrate, but not phorbol 12-myristate 13-acetate, induced MLC phosphorylation and muscle contraction in a dose- and time-dependent manner." | 3.67 | Correlative studies on the effect of carbachol on myo-inositol trisphosphate accumulation, myosin light chain phosphorylation and contraction in sphincter smooth muscle of rabbit iris. ( Abdel-Latif, AA; Akhtar, RA; Howe, PH; Naderi, S, 1986) |
| " Desensitized tissues showed a significant decrease in epinephrine-induced myo-inositol trisphosphate (IP3) accumulation, 1,2-diacylglycerol (DG) formation, measured as phosphatidate, arachidonic acid (AA) liberation, measured by radiochromatography, prostaglandin (PG) E2 release, measured by radiochromatography and radioimmunoassay, and muscle contraction." | 3.67 | Alpha 1-adrenergic receptor induced subsensitivity and supersensitivity in rabbit iris-ciliary body. Effects on myo-inositol trisphosphate accumulation, arachidonate release, and prostaglandin synthesis. ( Abdel-Latif, AA; Yousufzai, SY, 1987) |
| "Intraocular pressure was measured in conscious dogs and conscious laser-induced ocular hypertensive monkeys." | 1.43 | Prostaglandin E2-Glyceryl Ester: In Vivo Evidence for a Distinct Pharmacological Identity from Intraocular Pressure Studies. ( Poloso, NJ; Wang, JW; Woodward, DF, 2016) |
| "Bimatoprost is a synthetic analog of prostaglandin F(2 alpha) ethanolamide (prostamide F(2 alpha)), and shares a pharmacological profile consistent with that of the prostamides." | 1.33 | Bimatoprost and prostaglandin F(2 alpha) selectively stimulate intracellular calcium signaling in different cat iris sphincter cells. ( Chen, J; Krauss, AH; Nieves, AL; Protzman, CE; Sachs, G; Scott, DF; Spada, CS; Wheeler, LA; Woodward, DF, 2005) |
| " Pharmacokinetic evaluation in the mouse and rat revealed that oral SB 235375 was well absorbed systemically but did not effectively cross the blood-brain barrier." | 1.31 | Nonpeptide tachykinin receptor antagonists. III. SB 235375, a low central nervous system-penetrant, potent and selective neurokinin-3 receptor antagonist, inhibits citric acid-induced cough and airways hyper-reactivity in guinea pigs. ( Barone, FC; Bush, B; Foley, JJ; Giardina, GA; Griswold, DE; Grugni, M; Hay, DW; Kilian, D; Kotzer, CJ; Legos, JJ; Lundberg, D; Luttmann, MA; Martin, LD; Potts, W; Raveglia, LF; Sandhu, P; Sarau, HM; Schmidt, DB; Underwood, DC, 2002) |
| "Desloratadine was found to be a competitive antagonist (pA2 = 6." | 1.30 | Anticholinergic effects of desloratadine, the major metabolite of loratadine, in rabbit and guinea-pig iris smooth muscle. ( Antón, F; Beleta, J; Cardelús, I; Palacios, JM, 1999) |
| "Ryanodine abolished the increase in [Ca2+]i induced by NE but slightly inhibited the tension." | 1.29 | Contractile responses and calcium movements induced by alpha 1-adrenoceptor stimulant, norepinephrine, in rabbit iris dilator muscle. ( Kokubu, N; Satoh, M; Takayanagi, I, 1993) |
| "Bradykinin pretreatment reduced the resiniferatoxin response by about 50%; resiniferatoxin pretreatment completely abolished the response to bradykinin." | 1.28 | Effect of resiniferatoxin on the isolated rabbit iris sphincter muscle: comparison with capsaicin and bradykinin. ( Håkanson, R; Wang, ZY, 1992) |
| " Both antagonists caused a rightward shift of the dose-response curve for CCK-8s on the monkey iris sphincter." | 1.28 | Cholecystokinin contracts isolated human and monkey iris sphincters; a study with CCK receptor antagonists. ( Almegård, B; Bill, A; Stjernschantz, J, 1992) |
| " The dose-response curve for noradrenaline (NA) was significantly shifted to the left 7 days after denervation (ca." | 1.28 | Decrease in neuronal uptake of noradrenaline simply explains the supersensitivity after sympathectomy in the rat iris dilator. ( Imaizumi, Y; Kawai, T; Shibata, K; Takei, S; Watanabe, M, 1989) |
| " The dose-response relationships both for the muscle tension and for the c-AMP level were similar." | 1.27 | Effects of vasoactive intestinal polypeptide (VIP) and cyclic AMP on isolated dilator pupillae muscle of albino rabbit eye. ( Hayashi, K; Masuda, K; Mochizuki, M, 1983) |
| "8% of the MER) without altering the EC50 value (5 X 10(-6) M) of the phenylephrine dose-response curve." | 1.27 | Effects of neuropeptide Y on the isolated rabbit iris dilator muscle. ( Davis, M; Krupin, T; Littzi, J; Piccone, M; Stone, RA; Wax, MB, 1988) |
| "Atropine was about 2 orders of magnitude more potent than PZ in inhibiting the CCh-induced biochemical and pharmacological responses and [3H] QNB binding, indicating the preponderance of M2 receptors in this smooth muscle." | 1.27 | M2 muscarinic receptor subtype is associated with inositol trisphosphate accumulation, myosin light chain phosphorylation and contraction in sphincter smooth muscle of rabbit iris. ( Abdel-Latif, AA; Akhtar, RA; Honkanen, RE; Howe, PH, 1987) |
| " The shift of the dose-response curve for bethanechol (BeCh) after denervation was comparable to that for ACh." | 1.27 | Parasympathetic denervation supersensitivity in the rat iris sphincter muscle: an in vitro study. ( Hasegawa, N; Imaizumi, Y; Watanabe, M, 1987) |
| "No substance P-fibres were found in the cornea, while the sclera contained very few such elements." | 1.26 | Substance P-immunoreactive nerve fibres in the anterior segment of the rabbit eye. Distribution and possible physiological significance. ( Håkanson, R; Leander, S; Lorén, I; Mandahl, A; Sundler, F; Tornqvist, K, 1982) |
| "Indomethacin-treated bovine iris-ciliary body microsomes (IBIM) have been studied for their ability to convert PG endoperoxides into either thromboxane-A2 (TxA2)-like or prostacyclin (PGI2)-like activity." | 1.26 | Microsomal preparations of normal bovine iris-ciliary body generate prostacyclin-like but not thromboxane-A2-activity. ( Eakins, HM; Eakins, KE; Kulkarni, FS; Saber, WL, 1977) |
| "Thromboxane A2 (TxA2) has either no effect or may cause a slight relaxation of the sphincter." | 1.26 | The high yield of prostacyclin biosynthesis by the iris and its effects on the intraocular muscles. ( de Deckere, EA; Dutilh, CE; van Alphen, GW, 1978) |
| " Dose-response curves and ED50 values for levarterenol or phenylephrine in control and 6-hydroxydopamine-denervated tissues, both in the presence and absence of corticosterone, are shown." | 1.26 | Role of neuronal and extraneuronal uptake in responses of rabbit iris dilator muscle to levarterenol and phenylephrine. ( Ahlquist, RP; Carrier, GO; Matheny, JL, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 127 (53.81) | 18.7374 |
| 1990's | 76 (32.20) | 18.2507 |
| 2000's | 29 (12.29) | 29.6817 |
| 2010's | 3 (1.27) | 24.3611 |
| 2020's | 1 (0.42) | 2.80 |
| Authors | Studies |
|---|---|
| Safa, BN | 1 |
| Bahrani Fard, MR | 1 |
| Ethier, CR | 1 |
| Woodward, DF | 3 |
| Poloso, NJ | 1 |
| Wang, JW | 2 |
| Monjok, EM | 1 |
| Kulkarni, KH | 1 |
| Kouamou, G | 1 |
| McKoy, M | 1 |
| Opere, CA | 3 |
| Bongmba, ON | 1 |
| Njie, YF | 1 |
| Ohia, SE | 3 |
| Fan, X | 1 |
| Hearne, L | 1 |
| Lei, B | 1 |
| Miles, JH | 1 |
| Takahashi, N | 1 |
| Yao, G | 1 |
| Inoue-Mochita, M | 1 |
| Inoue, T | 1 |
| Epstein, DL | 1 |
| Blumer, KJ | 1 |
| Rao, PV | 1 |
| Okano, M | 1 |
| Uchikawa, Y | 1 |
| Tanaka, N | 1 |
| Mutoh, J | 1 |
| Ohkura, M | 1 |
| Hisa, H | 1 |
| Yamamoto, R | 3 |
| YOGO, T | 1 |
| KANEDA, T | 1 |
| NEZU, Y | 1 |
| HARADA, Y | 1 |
| HARA, Y | 1 |
| TAGAWA, M | 1 |
| URAKAWA, N | 1 |
| SHIMIZU, K | 2 |
| Flach, AJ | 1 |
| Goseki, T | 1 |
| Ishikawa, H | 3 |
| Ogasawara, S | 1 |
| Mashimo, K | 1 |
| Nemoto, N | 1 |
| Taguchi, Y | 1 |
| Yago, K | 1 |
| Akinlabi, GA | 1 |
| Asowata, OE | 1 |
| Ozolua, RI | 1 |
| Akpaja, OO | 1 |
| Iyawe, V | 1 |
| Filipe, JA | 1 |
| Nunes, JP | 1 |
| El Sayah, M | 2 |
| Calixto, JB | 4 |
| Ansari, HR | 4 |
| Davis, AM | 1 |
| Kaddour-Djebbar, I | 4 |
| Abdel-Latif, AA | 35 |
| AMBACHE, N | 2 |
| APTER, JT | 1 |
| Grumann Júnior, A | 1 |
| Alves, RV | 2 |
| Huang, EC | 1 |
| Barocas, VH | 1 |
| Akhtar, RA | 12 |
| Spada, CS | 1 |
| Krauss, AH | 1 |
| Chen, J | 1 |
| Protzman, CE | 1 |
| Nieves, AL | 1 |
| Wheeler, LA | 2 |
| Scott, DF | 1 |
| Sachs, G | 1 |
| Zhu, L | 1 |
| Cui, YY | 1 |
| Feng, JM | 1 |
| Wu, XJ | 1 |
| Chen, HZ | 1 |
| Rocha-Sousa, A | 2 |
| Saraiva, J | 1 |
| Henriques-Coelho, T | 1 |
| Falcão-Reis, F | 2 |
| Correia-Pinto, J | 1 |
| Leite-Moreira, AF | 2 |
| Clarke, RJ | 1 |
| Hasegawa, Y | 1 |
| Nishimura, J | 1 |
| Niiro, N | 1 |
| Hirano, K | 1 |
| Ishibashi, T | 1 |
| Kanaide, H | 1 |
| Wan, Z | 1 |
| Cornell, CL | 1 |
| Fliri, HG | 1 |
| Martos, JL | 1 |
| Pettit, SN | 1 |
| Kharlamb, AB | 1 |
| Garst, ME | 1 |
| Landsverk, KJ | 1 |
| Struble, CS | 1 |
| Stamer, WD | 1 |
| Sharif, NA | 1 |
| Koella, WP | 1 |
| Rubin, R | 1 |
| Schaeppi, U | 2 |
| Unger, WG | 2 |
| Tighe, J | 1 |
| Reibaldi, A | 1 |
| Lograno, MD | 1 |
| Avitabile, T | 1 |
| Tornqvist, K | 1 |
| Mandahl, A | 1 |
| Leander, S | 3 |
| Lorén, I | 1 |
| Håkanson, R | 13 |
| Sundler, F | 2 |
| Ueda, N | 8 |
| Muramatsu, I | 12 |
| Sakakibara, Y | 1 |
| Fujiwara, M | 10 |
| Dong, YJ | 2 |
| Jones, RL | 2 |
| Zhang, SQ | 1 |
| Butler, JM | 1 |
| Ohara, K | 1 |
| Cole, DF | 1 |
| Hayashi, H | 3 |
| Björkroth, U | 1 |
| Suzuki, R | 13 |
| Kobayashi, S | 12 |
| Hedqvist, P | 2 |
| Gustafsson, L | 2 |
| Hjemdahl, P | 1 |
| Svanborg, K | 1 |
| Hayashi, K | 1 |
| Mochizuki, M | 1 |
| Masuda, K | 1 |
| Imaizumi, Y | 10 |
| Banno, H | 2 |
| Watanabe, M | 12 |
| Takenawa, T | 1 |
| Oso, T | 1 |
| Akesson, C | 1 |
| Swanson, C | 1 |
| Patil, PN | 7 |
| Narita, S | 2 |
| Matheny, JL | 6 |
| Wang, ZY | 9 |
| Tung, SR | 3 |
| Strichartz, GR | 3 |
| Hall, JM | 1 |
| Mitchell, D | 1 |
| Morton, IK | 1 |
| Feng, DM | 2 |
| Wang, YL | 1 |
| Wong, K | 1 |
| Folkers, K | 4 |
| Masuda, Y | 2 |
| Yamahara, NS | 3 |
| Tanaka, M | 2 |
| Ryang, S | 1 |
| Kawai, T | 3 |
| Birney, DM | 1 |
| Cole, DC | 1 |
| Crosson, CE | 1 |
| Kahl, BF | 1 |
| Neff, BW | 1 |
| Reid, TW | 1 |
| Ren, K | 1 |
| Walkup, RD | 1 |
| Glasser, A | 1 |
| Murphy, CJ | 1 |
| Troilo, D | 1 |
| Howland, HC | 1 |
| Fuder, H | 4 |
| Selbach, M | 1 |
| Kunitomo, M | 1 |
| Imaizumi, N | 1 |
| Sameshima, E | 1 |
| Wiklund, CU | 1 |
| Wiklund, NP | 2 |
| Gustafsson, LE | 2 |
| Liljebris, C | 1 |
| Selén, G | 1 |
| Resul, B | 1 |
| Stjernschantz, J | 2 |
| Hacksell, U | 1 |
| Kigoshi, S | 1 |
| Oda, Y | 1 |
| Kokubu, N | 3 |
| Satoh, M | 3 |
| Takayanagi, I | 14 |
| Shinkai, M | 1 |
| Tsuruoka, H | 1 |
| Wakabayashi, S | 1 |
| Yamamoto, Y | 2 |
| el-Mowafy, AM | 1 |
| Wang, XL | 1 |
| Tachado, SD | 8 |
| Virdee, K | 1 |
| Hollenberg, MD | 1 |
| Barnett, NL | 3 |
| Osborne, NN | 3 |
| Shiraishi, K | 4 |
| Zhang, Y | 1 |
| Hashimoto, Y | 1 |
| Hasegawa, N | 3 |
| Suzuki, N | 1 |
| Yousufzai, SY | 11 |
| Ye, Z | 1 |
| Gould, DJ | 3 |
| Vidovic, M | 2 |
| Hill, CE | 7 |
| Luttmann, W | 1 |
| Chuman, T | 2 |
| Chuman, H | 2 |
| Nao-i, N | 2 |
| Sawada, A | 2 |
| Wada, A | 2 |
| Husain, S | 2 |
| Strigas, J | 1 |
| Burcher, E | 1 |
| KAMEI, CH | 1 |
| Fujimoto, N | 1 |
| Shichi, H | 1 |
| Marathe, GK | 1 |
| Miller, DD | 1 |
| Shinkai-Goromaru, M | 1 |
| Samejima, H | 1 |
| Medhurst, AD | 3 |
| Parsons, AA | 2 |
| Roberts, JC | 1 |
| Hay, DW | 4 |
| Kageyama, M | 3 |
| Fujita, H | 3 |
| Nakata, K | 3 |
| Shirasawa, E | 3 |
| Kobayashi, H | 1 |
| Kanai, A | 2 |
| Goto, W | 1 |
| Martin, LD | 2 |
| Griswold, DE | 2 |
| Newhouse, MJ | 1 |
| Hirst, GD | 1 |
| Edwards, FR | 1 |
| Sandow, SL | 2 |
| Ding, KH | 1 |
| Choppin, A | 1 |
| Eglen, RM | 1 |
| Hegde, SS | 1 |
| DeSantis, L | 2 |
| Tian, B | 1 |
| Millar, C | 1 |
| Kaufman, PL | 3 |
| Bershadsky, A | 1 |
| Becker, E | 1 |
| Geiger, B | 1 |
| Giardina, GA | 2 |
| Raveglia, LF | 2 |
| Grugni, M | 2 |
| Sarau, HM | 2 |
| Farina, C | 1 |
| Graziani, D | 1 |
| Schmidt, DB | 2 |
| Rigolio, R | 1 |
| Luttmann, M | 1 |
| Cavagnera, S | 1 |
| Foley, JJ | 2 |
| Vecchietti, V | 1 |
| Cardelús, I | 1 |
| Antón, F | 1 |
| Beleta, J | 1 |
| Palacios, JM | 1 |
| Nakamura, S | 1 |
| Taniguchi, T | 2 |
| Suzuki, F | 1 |
| Akagi, Y | 1 |
| Graham, J | 1 |
| Awe, SO | 2 |
| LeDay, AM | 2 |
| Rice, JC | 2 |
| Ramos, G | 1 |
| Harris, LC | 1 |
| Grumann-Júnior, A | 1 |
| Dias, MA | 1 |
| Boteon, JE | 1 |
| Ikeno, N | 1 |
| Furuta, M | 1 |
| Ohya, S | 1 |
| Gao, G | 1 |
| Matutte, B | 1 |
| Ameh, FA | 1 |
| Underwood, DC | 1 |
| Kotzer, CJ | 1 |
| Bush, B | 1 |
| Potts, W | 1 |
| Sandhu, P | 1 |
| Lundberg, D | 1 |
| Kilian, D | 1 |
| Legos, JJ | 1 |
| Barone, FC | 1 |
| Luttmann, MA | 1 |
| Ahlquist, RP | 2 |
| van Alphen, GW | 4 |
| Crawford, CG | 1 |
| Cook, HW | 1 |
| Lands, WE | 1 |
| Kalsner, S | 1 |
| Fonteles, MC | 1 |
| Conti-Tronconi, B | 1 |
| Gotti, C | 1 |
| Paggi, P | 1 |
| Rossi, A | 1 |
| Grimes, MJ | 1 |
| Carrier, GO | 2 |
| Lagercrantz, H | 1 |
| Kulkarni, FS | 1 |
| Eakins, HM | 1 |
| Saber, WL | 1 |
| Eakins, KE | 2 |
| Dutilh, CE | 1 |
| de Deckere, EA | 1 |
| Lütjen-Drecoll, E | 1 |
| Bárány, EH | 2 |
| Wilhelm, PB | 1 |
| Alphen, GW | 1 |
| Kaumann, AJ | 1 |
| Hennekes, R | 1 |
| Tomlinson, DR | 1 |
| Claesson, H | 1 |
| Bárány, E | 1 |
| Zucker, R | 1 |
| Nolte, J | 1 |
| Kulkarni, PS | 1 |
| Purves, RD | 2 |
| Watanabe, H | 1 |
| Burnstock, G | 3 |
| King, VM | 1 |
| Angel, MA | 1 |
| Gabella, G | 1 |
| Raeymaekers, L | 1 |
| Green, K | 1 |
| McPherson, JC | 1 |
| Smith, JP | 1 |
| Zhou, CJ | 1 |
| De, S | 1 |
| Okamura, T | 1 |
| Wang, Y | 1 |
| Toda, N | 1 |
| Kivelä, T | 1 |
| Fuchs, U | 1 |
| Tarkkanen, A | 1 |
| Almegård, B | 1 |
| Bill, A | 1 |
| Bognar, IT | 2 |
| Altes, U | 1 |
| Beinhauer, C | 1 |
| Kessler, I | 1 |
| Zhang, YW | 2 |
| Anderson, JA | 1 |
| Malfroy, B | 1 |
| Richard, NR | 1 |
| Kullerstrand, L | 1 |
| Lucas, C | 1 |
| Binder, PS | 1 |
| Asano, N | 1 |
| Ekblad, E | 1 |
| Wahlestedt, C | 1 |
| Wilson, NH | 1 |
| Nakanishi, S | 2 |
| Hosoki, R | 2 |
| Hisayama, T | 2 |
| Beding, B | 1 |
| Ljungqvist, A | 1 |
| Chu, JY | 1 |
| Trojnar, J | 1 |
| Chen, AL | 1 |
| Yoshino, H | 8 |
| Carter, KD | 1 |
| Konno, F | 4 |
| Schöpf, J | 1 |
| Unckell, J | 1 |
| Wesner, MT | 1 |
| Melchiorre, C | 1 |
| Tacke, R | 1 |
| Mutschler, E | 1 |
| Lambrecht, G | 1 |
| Barr, L | 1 |
| Geppetti, P | 1 |
| Patacchini, R | 1 |
| Meini, S | 1 |
| Manzini, S | 1 |
| Baumann, B | 1 |
| Dammann, F | 1 |
| Knöll, B | 1 |
| Meincke, M | 1 |
| Pallas, S | 1 |
| Shibata, K | 1 |
| Takei, S | 1 |
| Nakayama, M | 1 |
| Pilar, G | 3 |
| Nuñez, R | 1 |
| McLennan, IS | 1 |
| Meriney, SD | 1 |
| Yoshitomi, T | 3 |
| Ito, Y | 3 |
| Kameda, H | 1 |
| Kubo, H | 1 |
| Furukawa, A | 1 |
| Toyoda, T | 1 |
| Too, HP | 1 |
| Hanley, MR | 1 |
| Koss, MC | 1 |
| Logan, LG | 1 |
| Gherezghiher, T | 1 |
| Howe, PH | 3 |
| Naderi, S | 1 |
| Inomata, H | 1 |
| Piccone, M | 1 |
| Littzi, J | 1 |
| Krupin, T | 1 |
| Stone, RA | 1 |
| Davis, M | 1 |
| Wax, MB | 1 |
| Teranishi, H | 1 |
| Honkanen, RE | 1 |
| Delamere, NA | 1 |
| Williams, RN | 1 |
| Kargacin, GJ | 1 |
| Detwiler, PB | 1 |
| Kuchnow, KP | 2 |
| Knyihár, E | 1 |
| Gannon, BJ | 1 |
| Malmfors, T | 1 |
| Rogers, DC | 1 |
| Ehinger, B | 1 |
| Falck, B | 1 |
| Persson, H | 2 |
| Posner, J | 1 |
| Yamauchi, DN | 1 |
| Harris, LS | 2 |
| Shimmyo, M | 1 |
| Mittag, TW | 2 |
| Taylor, SA | 1 |
| Chamley, JH | 1 |
| Mark, GE | 1 |
| Fry, DM | 1 |
| Vaughan, PC | 2 |
| Denmark, LW | 1 |
| Cohn, K | 1 |
| Galin, MA | 1 |
| Martin, R | 1 |
| Davanger, M | 1 |
| Takao, M | 1 |
| Heckmann, K | 1 |
| Ritter, K | 1 |
| Schwedler, T | 1 |
| Sonmark, B | 1 |
| Kessler, J | 1 |
| Abrams, JD | 1 |
| DeSantis, LM | 1 |
| Mellanby, J | 1 |
| Pope, D | 1 |
| Singer, R | 1 |
| Ber, A | 1 |
| Dodd, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of Systemic Alfuzosin and Tamsulosin Hydrochloride on Choroidal Thickness and Pupil Diameter Sizes in Cases With Benign Prostatic Hyperplasia[NCT03144596] | Phase 4 | 63 participants (Actual) | Interventional | 2015-10-29 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for 2-propanol and Muscle Contraction
| Article | Year |
|---|---|
Inositol phospholipids in stimulated smooth muscles.
Topics: Animals; Aorta; Calcium; Ileum; In Vitro Techniques; Iris; Male; Muscle Contraction; Muscle, Smooth; | 1982 |
Calcium-mobilizing receptors, polyphosphoinositides, generation of second messengers and contraction in the mammalian iris smooth muscle: historical perspectives and current status.
Topics: Animals; Diglycerides; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Iris; Muscle Contraction; | 1989 |
Photomechanical coupling in the vertebrate sphincter pupillae.
Topics: Animals; Iris; Muscle Contraction; Pupil; Vertebrates | 1989 |
233 other studies available for 2-propanol and Muscle Contraction
| Article | Year |
|---|---|
Topics: Glaucoma, Angle-Closure; Humans; Iridium; Iris; Muscle Contraction; Muscle, Smooth | 2022 |
Prostaglandin E2-Glyceryl Ester: In Vivo Evidence for a Distinct Pharmacological Identity from Intraocular Pressure Studies.
Topics: Animals; Cats; Dinoprostone; Dogs; Female; Intraocular Pressure; Iris; Macaca fascicularis; Male; Mu | 2016 |
Inhibitory action of hydrogen sulfide on muscarinic receptor-induced contraction of isolated porcine irides.
Topics: Animals; Carbachol; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Dose-Response Relationsh | 2008 |
Weak gender effects on transient pupillary light reflex.
Topics: Adaptation, Ocular; Adolescent; Age Factors; Aging; Dark Adaptation; Female; Humans; Iris; Male; Mes | 2009 |
RGS2-deficient mice exhibit decreased intraocular pressure and increased retinal ganglion cell survival.
Topics: Animals; Aqueous Humor; Base Sequence; Cell Survival; Ciliary Body; Cornea; DNA Primers; Intraocular | 2009 |
Rho-kinase, but not protein kinase C, is involved in generation of the spontaneous tone in the resting phase of the isolated pig iris sphincter muscle.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Iris; Muscle Contraction; Muscle, Smoo | 2009 |
Effects of various selective phosphodiesterase inhibitors on relaxation and cyclic nucleotide contents in porcine iris sphincter.
Topics: Animals; Carbachol; Colforsin; Female; Iris; Male; Muscle Contraction; Nitroprusside; Phosphodiester | 2009 |
Intraoperative floppy iris syndrome: pathophysiology, prevention, and treatment.
Topics: Adrenergic alpha-Antagonists; Animals; Autonomic Agents; Cataract Extraction; Humans; Intraoperative | 2009 |
Effects of tamsulosin and silodosin on isolated albino and pigmented rabbit iris dilators: possible mechanism of intraoperative floppy-iris syndrome.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Animals; Dose-Respons | 2012 |
Contractile effect of aqueous Pleurotus tuberregium extract on the isolated bovine iris.
Topics: Acetylcholine; Animals; Atropine; Cattle; Drug Combinations; Fungal Proteins; Iris; Muscle Contracti | 2013 |
Functional importance of the actin cytoskeleton in contraction of bovine iris sphincter muscle.
Topics: Actin Cytoskeleton; Animals; Carbachol; Cattle; Cytoskeleton; Dose-Response Relationship, Drug; In V | 2002 |
Study of the mechanisms involved in the bradykinin-induced contraction of the pig iris sphincter muscle in vitro.
Topics: Animals; Atropine; Bradykinin; Bradykinin Receptor Antagonists; Cyclooxygenase Inhibitors; Dose-Resp | 2003 |
Effects of prostaglandin F2alpha and latanoprost on phosphoinositide turnover, myosin light chain phosphorylation and contraction in cat iris sphincter.
Topics: Animals; Antihypertensive Agents; Cats; Dinoprost; Dose-Response Relationship, Drug; In Vitro Techni | 2003 |
Irin, a smooth-muscle contracting substance present in rabbit iris.
Topics: Animals; Iris; Muscle Contraction; Muscles; Rabbits | 1955 |
Distribution of contractile forces in the iris of cats and dogs.
Topics: Animals; Cats; Dogs; Iris; Iris Plant; Muscle Contraction | 1960 |
New evidence on the mechanisms underlying bradykinin-mediated contraction of the pig iris sphincter in vitro.
Topics: Animals; Benzamides; Bradykinin; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Re | 2003 |
Effects of prostaglandin F2alpha, latanoprost and carbachol on phosphoinositide turnover, MAP kinases, myosin light chain phosphorylation and contraction and functional existence and expression of FP receptors in bovine iris sphincter.
Topics: Animals; Antihypertensive Agents; Carbachol; Cattle; Culture Techniques; Dinoprost; Dose-Response Re | 2004 |
The role of calcium channels in substance P-induced contractile response in the rat iris.
Topics: Amiloride; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Econazole; In Vitro Techniq | 2003 |
Active iris mechanics and pupillary block: steady-state analysis and comparison with anatomical risk factors.
Topics: Animals; Aqueous Humor; Biomechanical Phenomena; Computer Simulation; Elasticity; Glaucoma, Angle-Cl | 2004 |
Species differences in the effects of prostanoids on MAP kinase phosphorylation, myosin light chain phosphorylation and contraction in bovine and cat iris sphincter smooth muscle.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Cats; Cattle; Dinoprost | 2005 |
Bimatoprost and prostaglandin F(2 alpha) selectively stimulate intracellular calcium signaling in different cat iris sphincter cells.
Topics: Amides; Animals; Bimatoprost; Calcium; Calcium Signaling; Carbachol; Cats; Cells, Cultured; Choliner | 2005 |
Aceclidine and pilocarpine interact differently with muscarinic receptor in isolated rabbit iris muscle.
Topics: Animals; Carbachol; Iris; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Pilocarpine; Quin | 2006 |
Ghrelin as a novel locally produced relaxing peptide of the iris sphincter and dilator muscles.
Topics: Animals; Anterior Eye Segment; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Ep | 2006 |
Shaping the pupil's response to light in the hooded rat.
Topics: Animals; Electric Stimulation; Female; Ganglia, Parasympathetic; Iris; Light; Male; Muscle Contracti | 2007 |
Prostaglandin F2alpha, but not latanoprost, increases the Ca2+ sensitivity of the pig iris sphincter muscle.
Topics: Animals; Antihypertensive Agents; Calcium; Carbachol; Dinoprost; Enzyme Inhibitors; Intracellular Si | 2006 |
Bimatoprost, prostamide activity, and conventional drainage.
Topics: Aged; Aged, 80 and over; Amides; Animals; Antihypertensive Agents; Aqueous Humor; Bimatoprost; Calci | 2007 |
The obestatin/ghrelin system as a novel regulatory mechanism of iris muscle contraction.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Epinephrine; Ghrelin; Ir | 2008 |
Cat iris sphincter smooth-muscle contraction: comparison of FP-class prostaglandin analog agonist activities.
Topics: Animals; Cats; Cattle; Ciliary Body; Corpus Luteum; Dose-Response Relationship, Drug; Female; Humans | 2008 |
Effects of serotonin upon the isolated iris sphincter of the cat.
Topics: Acetylcholine; Animals; Atropine; Cats; Creatine; Desipramine; Electric Stimulation; Electrophysiolo | 1967 |
The response of the isolated iris sphincter muscle of various mammalian species to substance P.
Topics: Animals; Carbachol; Cats; Cattle; Dogs; Dose-Response Relationship, Drug; Humans; In Vitro Technique | 1984 |
Iris receptors of fresh human eyes.
Topics: Adrenergic beta-Antagonists; Humans; Iris; Muscle Contraction; Muscle Relaxation; Myofibrils; Parasy | 1984 |
Substance P-immunoreactive nerve fibres in the anterior segment of the rabbit eye. Distribution and possible physiological significance.
Topics: Animals; Atropine; Electric Stimulation; Eye; Fluorescent Antibody Technique; Iris; Muscle Contracti | 1982 |
Noncholinergic, nonadrenergic contraction and substance P in rabbit iris sphincter muscle.
Topics: Acetylcholine; Animals; Baclofen; Capsaicin; Cold Temperature; Electric Stimulation; Female; In Vitr | 1981 |
Effects of prostaglandins and thromboxane analogues on bullock and dog iris sphincter preparations.
Topics: Animals; Cattle; Dinoprostone; Dogs; Epoprostenol; Iloprost; In Vitro Techniques; Iris; Male; Muscle | 1982 |
Sensory neural mechanisms in contraction of the isolated sphincter pupillae: the role for substance P and the effects of sensory denervation on the responses to miotics.
Topics: Animals; Bradykinin; Capsaicin; Carbachol; Dose-Response Relationship, Drug; Female; In Vitro Techni | 1982 |
Trigeminal nerve: the possible origin of substance p-nergic response in isolated rabbit iris sphincter muscle.
Topics: Animals; Bradykinin; Capsaicin; Carbachol; Electric Stimulation; Enkephalins; Female; In Vitro Techn | 1982 |
Effects of Met-enkephalin on the substance P-ergic and cholinergic responses in the rabbit iris sphincter muscle.
Topics: Animals; Carbachol; Choline; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Met | 1983 |
Inhibition of smooth muscle contractions induced by capsaicin and electrical transmural stimulation by a substance P antagonist.
Topics: Animals; Capsaicin; Electric Stimulation; Guinea Pigs; Ileum; Iris; Male; Muscle Contraction; Muscle | 1983 |
Different effects of substance P and vasoactive intestinal peptide on the motor function of bovine intraocular muscles.
Topics: Animals; Cattle; Ciliary Body; In Vitro Techniques; Iris; Muscle Contraction; Muscle Relaxation; Mus | 1983 |
[Effects of bradykinin and capsaicin on substance P-induced reactions in the iris sphincter muscle].
Topics: Animals; Bradykinin; Capsaicin; Electric Stimulation; In Vitro Techniques; Iris; Muscle Contraction; | 1983 |
Capsaicin and bradykinin-induced substance P-ergic responses in the iris sphincter muscle of the rabbit.
Topics: Animals; Atropine; Bradykinin; Capsaicin; Carbachol; Electric Stimulation; Female; Guanethidine; Iri | 1984 |
Supersensitivity of the rabbit iris sphincter muscle induced by trigeminal denervation: the role of substance P.
Topics: Action Potentials; Animals; Carbachol; Electric Stimulation; Female; Iris; Male; Muscle Contraction; | 1984 |
Aspects of prostaglandin action on autonomic neuroeffector transmission.
Topics: Adrenergic Fibers; Animals; Cattle; Cholinergic Fibers; Guinea Pigs; Ileum; Indomethacin; Iris; Kidn | 1980 |
Response of bovine intra-ocular muscles to transmural stimulation in the presence of various prostaglandins.
Topics: Action Potentials; Alprostadil; Animals; Cattle; Ciliary Body; Dinoprost; Dinoprostone; Electric Sti | 1983 |
Effects of vasoactive intestinal polypeptide (VIP) and cyclic AMP on isolated dilator pupillae muscle of albino rabbit eye.
Topics: Animals; Cyclic AMP; Dose-Response Relationship, Drug; Female; Iris; Male; Muscle Contraction; Muscl | 1983 |
Anomalous stabilizing action of Ca on sphincter smooth muscle of the rat iris.
Topics: Action Potentials; Animals; Barium; Calcium; Cell Membrane; Iris; Male; Membrane Potentials; Muscle | 1984 |
Cholinergic inhibitory response in the bovine iris dilator muscle.
Topics: Acetylcholine; Animals; Cholinergic Fibers; Electric Stimulation; Iris; Muscle Contraction; Muscle R | 1983 |
Muscarinic receptors of rabbit irides.
Topics: Animals; Atropine; Carbachol; Carboxylic Ester Hydrolases; Dose-Response Relationship, Drug; Drug In | 1983 |
Response of isolated rat iris dilator to adrenergic and cholinergic agents and electrical stimulation.
Topics: Acetylcholine; Animals; Atropine; Dose-Response Relationship, Drug; Electric Stimulation; Epinephrin | 1982 |
Effects of calcium blockers and Mn2+ on the response of isolated rat iris sphincter and dilator muscles to agonists and Ca2+.
Topics: Acetylcholine; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Gallopamil; In Vitro Technique | 1982 |
Adrenergic responsiveness in vitro of iris dilator muscle from rabbits with experimentally induced thyroid disorders.
Topics: Animals; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Iris; Isoproterenol; Male; M | 1980 |
Effects of ruthenium red and capsazepine on C-fibres in the rabbit iris.
Topics: Animals; Bradykinin; Capsaicin; Drug Interactions; Electric Stimulation; Female; Iris; Male; Muscle | 1993 |
Investigation of the specificity of FK 888 as a tachykinin NK1 receptor antagonist.
Topics: Action Potentials; Animals; Dipeptides; Female; Guinea Pigs; Histamine Release; In Vitro Techniques; | 1994 |
Typical and atypical NK1 tachykinin receptor characteristics in the rabbit isolated iris sphincter.
Topics: Animals; In Vitro Techniques; Iris; Male; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor | 1994 |
Pharmacological assessment of spantide II analogues.
Topics: Action Potentials; Amino Acid Sequence; Analgesics; Animals; Female; Guinea Pigs; Histamine Release; | 1994 |
Characterization of muscarinic receptors mediating relaxation and contraction in the rat iris dilator muscle.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Alkaloids; Anim | 1995 |
Use of beta-methylphenylalanine (beta MeF) residues to probe the nature of the interaction of substance P with its receptor: effects of beta MeF-containing substance P analogs on rabbit iris smooth muscle contraction.
Topics: Aminobutyrates; Animals; Iris; Molecular Probes; Muscle Contraction; Muscle, Smooth; Rabbits; Recept | 1995 |
The mechanism of lenticular accommodation in chicks.
Topics: Accommodation, Ocular; Animals; Chickens; Ciliary Body; Dissection; Electric Stimulation; Iris; Lase | 1995 |
The rabbit iris sphincter contains NK1 and NK3 but not NK2 receptors: a study with selective agonists and antagonists.
Topics: Animals; Dactinomycin; Female; Iris; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Neurokinin | 1993 |
Characterization of sensory neurotransmission and its inhibition via alpha 2B-adrenoceptors and via non-alpha 2-receptors in rabbit iris.
Topics: Animals; Cholinergic Fibers; Electric Stimulation; In Vitro Techniques; Iris; Kinins; Muscle Contrac | 1993 |
Pharmacological analysis of receptors involved in the late, tachykininergic contractile response to electrical transmural stimulation in isolated rabbit iris sphincter muscle.
Topics: Animals; Electric Stimulation; Iris; Male; Muscle Contraction; Peptides, Cyclic; Rabbits; Receptors, | 1993 |
Modulation of neuroeffector transmission by endogenous nitric oxide: a role for acetylcholine receptor-activated nitric oxide formation, as indicated by measurements of nitric oxide/nitrite release.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Atropine; Electric Stimulation; Female | 1993 |
Pertussis toxin-sensitive muscarinic relaxation in the rat iris dilator muscle.
Topics: Acetylcholine; Alkaloids; Animals; Atropine; Diamines; Dose-Response Relationship, Drug; Furans; GTP | 1995 |
Derivatives of 17-phenyl-18,19,20-trinorprostaglandin F2 alpha isopropyl ester: potential antiglaucoma agents.
Topics: Animals; Capillary Permeability; Cats; Dinoprost; Glaucoma; Haplorhini; Humans; Intraocular Pressure | 1995 |
Evidence for sympathetic, purinergic transmission in the iris dilator muscle of the rabbit.
Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Electric Stimulation; Female; Guaneth | 1994 |
Contractile responses and calcium movements induced by alpha 1-adrenoceptor stimulant, norepinephrine, in rabbit iris dilator muscle.
Topics: Adrenergic alpha-Agonists; Animals; Calcium; Calcium Channel Blockers; Cytosol; Fura-2; In Vitro Tec | 1993 |
Pre- and postjunctional actions of endothelin in the rat iris sphincter preparation.
Topics: Amino Acid Sequence; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Endothelin Rec | 1994 |
Non-specific actions of the non-peptide tachykinin receptor antagonists, CP-96,345, RP 67580 and SR 48968, on neurotransmission.
Topics: Action Potentials; Anesthetics, Local; Animals; Benzamides; Biphenyl Compounds; Bupivacaine; Electri | 1994 |
Characterization of iris sphincter smooth muscle endothelin receptor subtypes which are coupled to cyclic AMP formation and polyphosphoinositide hydrolysis.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Binding, Competitive; Cattle; Cyclic AMP; Endotheli | 1994 |
Studies on the properties of myo-inositol-1,4,5-trisphosphate 5-phosphatase and myo-inositol monophosphatase in bovine iris sphincter smooth muscle: effects of okadaic acid and protein phosphorylation.
Topics: Animals; Carbachol; Cattle; Disulfiram; Enzyme Activation; Ethers, Cyclic; Hydrogen-Ion Concentratio | 1994 |
M3 muscarinic receptors mediate an increase in both inositol trisphosphate production and cyclic AMP formation in dog iris sphincter smooth muscle.
Topics: Adenylyl Cyclases; Animals; Calcium; Calcium Channel Blockers; Carbachol; Cyclic AMP; Dogs; Inositol | 1994 |
Potentiation of sensory tachykininergic and parasympathetic cholinergic transmission by epidermal growth factor.
Topics: Acetylcholine; Alprostadil; Animals; Atropine; Capsaicin; Epidermal Growth Factor; Female; Genistein | 1993 |
The effect of serotonin on the rabbit isolated iris sphincter muscle.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Iris; Muscle Contraction; Muscle Relaxation; M | 1993 |
Inhibitory effect of pilocarpine on norepinephrine release from electrically stimulated iris dilator muscles of rabbits as a most possible mechanism of pilocarpine-induced miosis.
Topics: Animals; Atropine; Depression, Chemical; Dose-Response Relationship, Drug; Electric Stimulation; In | 1993 |
Protein kinase C is involved in cyclic adenosine monophosphate formation due to PGF2 alpha desensitization in bovine iris sphincter.
Topics: Adenylyl Cyclases; Alkaloids; Animals; Cattle; Chromatography, Ion Exchange; Cyclic AMP; Dinoprost; | 1993 |
Effects of ciliary ganglionectomy on contractile responses in the dilator muscle of the rat iris.
Topics: Animals; Ciliary Body; Cocaine; Dose-Response Relationship, Drug; Ganglia, Sympathetic; Ganglionecto | 1993 |
Subtype of muscarinic receptors mediating relaxation and contraction in the rat iris dilator smooth muscle.
Topics: Alkaloids; Animals; Atropine; Carbachol; Furans; In Vitro Techniques; Iris; Male; Muscle Contraction | 1993 |
Prostaglandins mediate the stimulatory effects of endothelin-1 on cAMP accumulation and inositol-1,4,5-trisphosphate production and contraction in cat iris sphincter.
Topics: Adenylyl Cyclases; Animals; Cats; Cattle; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug | 1995 |
Cross talk between receptors mediating contraction and relaxation in the arterioles but not the dilator muscle of the rat iris.
Topics: Animals; Arterioles; Base Sequence; Cyclic AMP; Female; GTP-Binding Proteins; In Vitro Techniques; I | 1995 |
Endothelin receptors in the cornea, iris and ciliary processes. Evidence from binding, secondary messenger and PCR studies.
Topics: Animals; Autoradiography; Base Sequence; Binding Sites; Ciliary Body; Colforsin; Cornea; Cyclic AMP; | 1993 |
Nitric oxide-sensitive and -insensitive contractions of the isolated rabbit iris sphincter muscle.
Topics: Animals; Arginine; Benzoates; Carbachol; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibi | 1996 |
Protein kinase C isoforms in iris sphincter smooth muscle: differential effects of phorbol ester on contraction and cAMP accumulation are species specific.
Topics: Animals; Carcinogens; Cats; Cattle; Cell Membrane; Cyclic AMP; Cyclooxygenase Inhibitors; Cytosol; D | 1996 |
Sensory nerves play an efferent role in the function of the arterioles, but not the dilator muscle, of the rat iris.
Topics: Adrenergic Fibers; Animals; Arterioles; Autoradiography; Base Sequence; Binding Sites; Calcitonin Ge | 1996 |
EFFECTS OF HISTAMINE AND RELATED COMPOUNDS ON THE BOVINE IRIS DILATOR.
Topics: Analysis of Variance; Animals; Cattle; Chlorpheniramine; Cimetidine; Diphenhydramine; Dose-Response | 1996 |
Effect of prostaglandins on cultured porcine iris sphincter muscle cells.
Topics: Animals; Carbachol; Cells, Cultured; Cyclic AMP; Dinoprost; Dinoprostone; Iris; Muscarinic Agonists; | 1996 |
Characterization of endothelin receptor subtypes mediating Ca2+ mobilization and contractile response in rabbit iris dilator muscle.
Topics: Animals; Calcium; Dose-Response Relationship, Drug; Endothelins; Fura-2; In Vitro Techniques; Iris; | 1996 |
Mediation by prostaglandins of the stimulatory effect of substance P on cyclic AMP production in dog iris sphincter smooth muscle.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Cyclooxygenase Inhibitors; Dinoprostone; Dogs; Dose-Response | 1996 |
Comparison of post-junctional alpha-adrenoceptors in iris dilator muscle of humans, and albino and pigmented rabbits.
Topics: Adult; Aged; Aged, 80 and over; Animals; Dose-Response Relationship, Drug; Female; Humans; In Vitro | 1996 |
The significant role of endothelin-3 in potentiating electrically stimulated contractions in the rat iris sphincter.
Topics: Animals; Bosentan; Electric Stimulation; Endothelin-1; Endothelin-3; Endothelins; Iris; Male; Muscle | 1997 |
Characterization of NK3 receptors in rabbit isolated iris sphincter muscle.
Topics: Adrenergic alpha-Antagonists; Animals; Autoradiography; Benzamides; Electric Stimulation; In Vitro T | 1997 |
Involvement of both L- and N-type voltage-dependent Ca2+ channels in KCl- and veratridine-evoked transmitter release from non-adrenergic, non-cholinergic nerves in the rabbit iris sphincter muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1997 |
Different responsiveness to nitric oxide-cyclic guanosine monophosphate pathway in cholinergic and tachykinergic contractions of the rabbit iris sphincter muscle.
Topics: Animals; Carbachol; Cyclic GMP; Cyclic N-Oxides; Female; Free Radical Scavengers; Imidazoles; Iris; | 1997 |
Effects of the immunosuppressant cyclosporin A on neurotransmitter release from peripheral non-adrenergic, non-cholinergic nerves.
Topics: Animals; Atropine; Calcium Channel Blockers; Capsaicin; Cyclosporine; Dipeptides; Immunosuppressive | 1997 |
FK506-binding proteins regulate smooth muscle contractility by altering neurotransmitter release.
Topics: Animals; Calcium Channel Blockers; Capsaicin; Dipeptides; Dose-Response Relationship, Drug; Immunosu | 1997 |
In vitro and in vivo characterization of NK3 receptors in the rabbit eye by use of selective non-peptide NK3 receptor antagonists.
Topics: Animals; In Vitro Techniques; Iris; Male; Miosis; Muscle Contraction; Muscle, Smooth; Neurokinin B; | 1997 |
A role for neuropeptide Y in rat iridial arterioles.
Topics: Animals; Arterioles; Capsaicin; Electric Stimulation; Female; Iris; Male; Muscle Contraction; Muscle | 1997 |
Electrical properties of iridial arterioles of the rat.
Topics: Animals; Arterioles; Electric Stimulation; Endothelium, Vascular; Iris; Membrane Potentials; Muscle | 1997 |
Actions of C-type natriuretic peptide and sodium nitroprusside on carbachol-stimulated inositol phosphate formation and contraction in ciliary and iris sphincter smooth muscles.
Topics: Aminoquinolines; Animals; Atrial Natriuretic Factor; Carbachol; Cats; Cattle; Ciliary Body; Cyclic A | 1997 |
Pharmacological characterization of muscarinic receptors in rabbit isolated iris sphincter muscle and urinary bladder smooth muscle.
Topics: Animals; Benzofurans; Dioxoles; Elapid Venoms; Female; Humans; In Vitro Techniques; Intercellular Si | 1998 |
Selectivity of muscarinic agonists including (+/-)-aceclidine and antimuscarinics on the human intraocular muscles.
Topics: Adult; Aged; Aged, 80 and over; Ciliary Body; Female; Humans; Iris; Male; Middle Aged; Muscarinic Ag | 1998 |
Effects of H-7 on the iris and ciliary muscle in monkeys.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Accommodation, Ocular; Actomyosin; Animals | 1998 |
Tyrosine kinase inhibitors suppress prostaglandin F2alpha-induced phosphoinositide hydrolysis, Ca2+ elevation and contraction in iris sphincter smooth muscle.
Topics: Animals; Calcium; Carbachol; Cardiotonic Agents; Cats; Dinoprost; Dose-Response Relationship, Drug; | 1998 |
Enhanced sensitivity of the iris sphincter to the muscarinic agonist carbachol at lower temperature.
Topics: Animals; Atropine; Body Temperature; Carbachol; Cold Temperature; Dogs; Dose-Response Relationship, | 1999 |
Discovery of a novel class of selective non-peptide antagonists for the human neurokinin-3 receptor. 2. Identification of (S)-N-(1-phenylpropyl)-3-hydroxy-2-phenylquinoline-4-carboxamide (SB 223412).
Topics: Animals; Calcium; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Humans; In Vitro Techniques; | 1999 |
Anticholinergic effects of desloratadine, the major metabolite of loratadine, in rabbit and guinea-pig iris smooth muscle.
Topics: Animals; Cholinergic Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Female; In Vi | 1999 |
Evaluation of alpha1-adrenoceptors in the rabbit iris: pharmacological characterization and expression of mRNA.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; D | 1999 |
Physiological and anatomical studies of the development of the sympathetic innervation to rat iris arterioles.
Topics: Adaptation, Ocular; Adrenergic alpha-Antagonists; Aging; Animals; Animals, Newborn; Arterioles; Calc | 1999 |
Effect of inhibition of cyclooxygenase on pre- and postjunctional actions of peroxides in the iris-ciliary body.
Topics: Animals; Benzene Derivatives; Carbachol; Cattle; Cholinergic Agonists; Ciliary Body; Cyclooxygenase | 2000 |
Mechanisms mediating substance P-induced contraction in the rat iris in vitro.
Topics: Animals; Calcium; Calcium Channels; Diffusion Chambers, Culture; Dose-Response Relationship, Drug; E | 2000 |
Molecular analysis of non-specific supersensitivity induced by AF64A in rat iris smooth muscle.
Topics: Animals; Aziridines; Calcium; Calcium-Binding Proteins; Calmodulin; Calmodulin-Binding Proteins; Cal | 2000 |
Mitogen-activated protein kinase inhibitors suppress prostaglandin F(2alpha)-induced myosin-light chain phosphorylation and contraction in iris sphincter smooth muscle.
Topics: Animals; Carbachol; Cats; Dinoprost; Enzyme Inhibitors; Flavonoids; Imidazoles; Iris; Miotics; Mitog | 2000 |
Role of catalase in pre- and postjunctional responses of mammalian irides to hydrogen peroxide.
Topics: Amitrole; Animals; Carbachol; Catalase; Cattle; Female; Hydrogen Peroxide; In Vitro Techniques; Iris | 2000 |
Activation of p42/p44 mitogen-activated protein kinase and contraction by prostaglandin F2alpha, ionomycin, and thapsigargin in cat iris sphincter smooth muscle: inhibition by PD98059, KN-93, and isoproterenol.
Topics: Adrenergic beta-Agonists; Animals; Benzylamines; Blotting, Western; Calcium-Transporting ATPases; Ca | 2001 |
Nonpeptide tachykinin receptor antagonists. III. SB 235375, a low central nervous system-penetrant, potent and selective neurokinin-3 receptor antagonist, inhibits citric acid-induced cough and airways hyper-reactivity in guinea pigs.
Topics: Acetates; Animals; Antitussive Agents; Behavior, Animal; Bronchial Hyperreactivity; Calcium; Central | 2002 |
Metabolic inhibition and adrenoceptor interconversion.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Dinitrophenols; Female; In Vitro Techn | 1975 |
The adrenergic receptors of the intraocular muscles of the human eye.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Ad | 1976 |
The effect of precursors, products, and product analogs of prostaglandin cyclooxygenase upon iris sphincter muscle.
Topics: Animals; Cats; Fatty Acids; Fatty Acids, Unsaturated; Flurbiprofen; Hydroxy Acids; In Vitro Techniqu | 1978 |
Mechanisms of inactivation of noradrenaline in the iris sphincter, tracheal muscle and facial artery of cattle: implications for beta-adrenoceptor-mediated responses.
Topics: Animals; Arteries; Cattle; Drug Interactions; Female; In Vitro Techniques; Iris; Male; Muscle Contra | 1978 |
alpha-Adrenoceptor alteration by alloxan diabetes in iris dilator muscle of the rabbit.
Topics: Animals; Diabetes Mellitus, Experimental; In Vitro Techniques; Iris; Muscle Contraction; Muscle, Smo | 1979 |
Acetylcholine receptors in the ciliary ganglion and in the iris muscle of the chick: specific binding and effect on the synaptic transmission of the neurotoxin from Naja naja siamensis.
Topics: Animals; Chickens; Cobra Neurotoxin Proteins; Elapid Venoms; Ganglia; In Vitro Techniques; Iris; Mus | 1979 |
Kinetic studies on dose-triphosphoinositide responses and dose-contraction responses in rabbit iris.
Topics: Animals; Atropine; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Iris; Kinetics; Ma | 1979 |
Potentiation by prostaglandins e1, e2, and f2alpha of the contraction response to transmural stimulation in the bovine iris sphincter muscle.
Topics: Acetylcholine; Animals; Cattle; Depression, Chemical; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic a | 1975 |
Microsomal preparations of normal bovine iris-ciliary body generate prostacyclin-like but not thromboxane-A2-activity.
Topics: Animals; Arteries; Cattle; Ciliary Body; Dogs; Epoprostenol; Humans; Indomethacin; Iris; Microsomes; | 1977 |
The high yield of prostacyclin biosynthesis by the iris and its effects on the intraocular muscles.
Topics: Animals; Arachidonic Acids; Cats; Ciliary Body; Epoprostenol; In Vitro Techniques; Iris; Muscle Cont | 1978 |
Light and electron microscopy of the anterior chamber angle structures following surgical disinsertion of the ciliary muscle in the cynomolgus monkey.
Topics: Animals; Anterior Chamber; Aqueous Humor; Cicatrix; Female; Gonioscopy; Haplorhini; Iris; Macaca; Ma | 1977 |
Potentiation of PG effects on the intraocular muscles of the cat by inhibition of PG synthesis.
Topics: Animals; Cats; Ciliary Body; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Syner | 1977 |
Recent observations concerning the effects of cholinergic drugs on outflow facility in monkeys.
Topics: Animals; Aqueous Humor; Ciliary Body; Haplorhini; Iris; Macaca fascicularis; Muscle Contraction; Pil | 1977 |
The affinity of atropine for muscarine receptors in human sphincter pupillae.
Topics: Atropine; Carbachol; Humans; In Vitro Techniques; Iris; Kinetics; Muscle Contraction; Muscle, Smooth | 1979 |
Effects of acetylcholine and norepinephrine on 45Ca uptake and efflux in rabbit iris smooth muscle.
Topics: Acetylcholine; Animals; Atropine; Calcium; Female; In Vitro Techniques; Iris; Lanthanum; Male; Muscl | 1979 |
The mode of action of tetrabenazine on peripheral noradrenergic nerves.
Topics: Animals; Histocytochemistry; In Vitro Techniques; Iris; Male; Muscle Contraction; Neurons; Norepinep | 1977 |
Effect of 6-hydroxydopamine in vitro on contractility and norepinephrine uptake of rabbit iris muscle.
Topics: Animals; Female; Hydroxydopamines; In Vitro Techniques; Iris; Male; Muscle Contraction; Muscle Dener | 1978 |
Time course of light induced changes in pilocarpine sensitivity of rat iris.
Topics: Animals; Iris; Light; Male; Muscle Contraction; Muscle, Smooth; Pilocarpine; Rats; Receptors, Cholin | 1978 |
Light-induced calcium release in a photosensitive vertebrate smooth muscle.
Topics: Animals; Calcium; Carbachol; Cricetinae; Dark Adaptation; In Vitro Techniques; Iris; Light; Mesocric | 1978 |
Role of neuronal and extraneuronal uptake in responses of rabbit iris dilator muscle to levarterenol and phenylephrine.
Topics: Animals; Corticosterone; Dilatation; Drug Interactions; Female; Hydroxydopamines; In Vitro Technique | 1977 |
The enzymatic conversion of prostaglandin endoperoxides to thromboxane-A2-like activity by human iris microsomes.
Topics: Animals; Ciliary Body; Dogs; Humans; Iris; Microsomes; Muscle Contraction; Prostaglandin Endoperoxid | 1977 |
Specificity of innervation of iris musculature by sympathetic nerve fibres in tissue culture.
Topics: Animals; Culture Techniques; Cytoplasmic Granules; Electric Stimulation; Ganglia, Autonomic; Iris; M | 1976 |
Effects of mydriatics and a miotic on ocular discomfort and pupil responses.
Topics: Humans; Iris; Muscle Contraction; Muscle, Smooth; Mydriatics; Phenylephrine; Pilocarpine; Pupil; Ref | 1976 |
Activity of prostaglandin E, F, A and B on sphincter, dilator and ciliary muscle preparations of the cat eye.
Topics: Animals; Atropine; Cats; Ciliary Body; Drug Synergism; Epinephrine; Indomethacin; Iris; Isoprotereno | 1975 |
Proceedings: The sphincter pupillae: contractions in Ca2+-free solution.
Topics: Animals; Calcium; Guinea Pigs; In Vitro Techniques; Iris; Muscle Contraction; Muscle, Smooth; Pupil | 1975 |
Effects of norepinephrine and acetylcholine on 32P incorporation into phospholipids of the rabbit iris muscle following unilateral superior cervical ganglionectomy.
Topics: Acetylcholine; Animals; Denervation; Ganglia, Autonomic; In Vitro Techniques; Iris; Muscle Contracti | 1975 |
Effects of isoproterenol and forskolin on carbachol- and fluoroaluminate-induced polyphosphoinositide hydrolysis, inositol trisphosphate production, and contraction in bovine iris sphincter smooth muscle: interaction between cAMP and IP3 second messenger
Topics: Aluminum; Animals; Carbachol; Cattle; Colforsin; Cyclic AMP; Deferoxamine; Fluorine; Hydrolysis; Ino | 1992 |
Effects of ageing on responses of rabbit iris smooth muscles to agonists and field stimulation.
Topics: Acetylcholine; Aging; Animals; Electric Stimulation; Electrodes; In Vitro Techniques; Iris; Male; Mu | 1992 |
The electrically evoked, tachykinin-mediated contractile response of the isolated rabbit iris sphincter muscle involves NK1 receptors only.
Topics: Animals; Electric Stimulation; Female; Iris; Male; Muscle Contraction; Neurokinin A; Rabbits; Recept | 1992 |
Carbachol stimulates adenylate cyclase and phospholipase C and muscle contraction-relaxation in a reciprocal manner in dog iris sphincter smooth muscle.
Topics: Adenylyl Cyclases; Animals; Calcium; Calmodulin; Carbachol; Cats; Cattle; Cyclic AMP; Dogs; Inositol | 1992 |
Alpha 1B-adrenoceptor mechanisms in rabbit iris dilator.
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; In Vitro Techniques; Iris; Male; Methoxamine; | 1992 |
(+/-)-CP-96,345, a selective tachykinin NK1 receptor antagonist, has non-specific actions on neurotransmission.
Topics: Animals; Biphenyl Compounds; Carbachol; Dinoprost; Electric Stimulation; Female; Guinea Pigs; Hypnot | 1992 |
Local generation and action of angiotensin II in dog iris sphincter muscle.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Dinoprost; Dogs; Dose-Response Relationship | 1992 |
Effect of resiniferatoxin on the isolated rabbit iris sphincter muscle: comparison with capsaicin and bradykinin.
Topics: Animals; Bradykinin; Capsaicin; Captopril; Diterpenes; Electric Stimulation; Female; Iris; Male; Mus | 1992 |
Cytoskeleton in neuroectodermally derived epithelial and muscle cells of the human iris and ciliary body.
Topics: Adult; Aged; Ciliary Body; Cytoskeleton; Epithelial Cells; Epithelium; Humans; Immunohistochemistry; | 1992 |
Endothelin-1 stimulates phosphatidylinositol hydrolysis in the iris/ciliary complex and is a potent constrictor of the sphincter muscle.
Topics: Animals; Atropine; Carbachol; Ciliary Body; Dose-Response Relationship, Drug; Endothelins; Hydrolysi | 1992 |
Cholecystokinin contracts isolated human and monkey iris sphincters; a study with CCK receptor antagonists.
Topics: Aged; Aged, 80 and over; Animals; Cholecystokinin; Female; Humans; In Vitro Techniques; Iris; Macaca | 1992 |
A muscarinic receptor different from the M1, M2, M3 and M4 subtypes mediates the contraction of the rabbit iris sphincter.
Topics: Animals; Evoked Potentials; Female; Guinea Pigs; Iris; Male; Methacholine Chloride; Muscle Contracti | 1992 |
Species differences in the effects of endothelin-1 on myo-inositol trisphosphate accumulation, cyclic AMP formation and contraction of isolated iris sphincter of rabbit and other species.
Topics: Animals; Calcium Channel Blockers; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Endot | 1991 |
The effect of M & B 22948 on carbachol-induced inositol trisphosphate accumulation and contraction in iris sphincter smooth muscle.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Carbachol; Cattle; Hydrolysis; Inositol 1,4,5-Trisphos | 1991 |
Substance P contracts the human iris sphincter: possible modulation by endogenous enkephalinase.
Topics: Aged; Aged, 80 and over; Carbachol; Female; Humans; Immunoenzyme Techniques; In Vitro Techniques; Ir | 1990 |
Spantide II, a novel tachykinin antagonist having high potency and low histamine-releasing effect.
Topics: Amino Acid Sequence; Animals; Guinea Pigs; Histamine Release; In Vitro Techniques; Iris; Male; Mast | 1990 |
Comparison of spantide II and CP-96,345 for blockade of tachykinin-evoked contractions of smooth muscle.
Topics: Analgesics; Animals; Biphenyl Compounds; Female; In Vitro Techniques; Iris; Male; Muscle Contraction | 1991 |
Effects of surgical sympathetic denervation on myo-inositol trisphosphate production and contraction in the dilator and sphincter smooth muscles of the rabbit iris: evidence for interaction between the cyclic AMP and calcium signaling systems.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Carbachol; Cyclic AMP; Female; Inositol 1,4,5-Trispho | 1991 |
Species differences in the effects of substance P on inositol trisphosphate accumulation and cyclic AMP formation, and on contraction in isolated iris sphincter of the mammalian eye: differences in receptor density.
Topics: Adenylyl Cyclases; Animals; Cats; Cattle; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Humans | 1991 |
Species differences in the effects of leukotriene D4 on inositol trisphosphate accumulation, cyclic AMP formation and contraction in iris sphincter of the mammalian eye.
Topics: Animals; Cats; Cattle; Cyclic AMP; Dinoprost; Humans; In Vitro Techniques; Inositol; Inositol 1,4,5- | 1990 |
Pharmaco-mechanical coupling in the response to acetylcholine and substance P in the smooth muscle of the rat iris sphincter.
Topics: Acetylcholine; Animals; Barium; Calcium; Capsaicin; Electric Stimulation; Iris; Male; Membrane Poten | 1985 |
Galanin: neuromodulatory and direct contractile effects on smooth muscle preparations.
Topics: Animals; Colon; Female; Galanin; Guinea Pigs; In Vitro Techniques; Iris; Jejunum; Male; Muscle Contr | 1985 |
Prostaglandin E receptor subtypes in smooth muscle: agonist activities of stable prostacyclin analogues.
Topics: Animals; Cats; Colon; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazid | 1986 |
Effects of substance P on inositol triphosphate accumulation, on contractile responses and on arachidonic acid release and prostaglandin biosynthesis in rabbit iris sphincter muscle.
Topics: Animals; Arachidonic Acids; Diglycerides; Dinoprostone; Dose-Response Relationship, Drug; Female; In | 1986 |
Effects of neurokinin A, substance P and electrical stimulation on the rabbit iris sphincter muscle.
Topics: Amino Acid Sequence; Animals; Capsaicin; Carbachol; Dose-Response Relationship, Drug; Electric Stimu | 1986 |
Pharmacological evidence for the possible coexistence of multiple receptor sites for mammalian tachykinins in rabbit iris sphincter smooth muscle.
Topics: Animals; Carbachol; Eledoisin; In Vitro Techniques; Iris; Muscle Contraction; Muscle, Smooth; Neurok | 1987 |
Comparison of the responses to the sensory neuropeptides, substance P, neurokinin A, neurokinin B and calcitonin gene-related peptide and to trigeminal nerve stimulation in the iris sphincter muscle of the rabbit.
Topics: Animals; Atropine; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Eledoisin; Fema | 1987 |
Blockade of sensory nerve mediated contraction of the rabbit iris sphincter by a series of novel tachykinin antagonists.
Topics: Animals; Colon; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Iris; Male; Muscle C | 1988 |
Species differences in the effects of prostaglandins on inositol trisphosphate accumulation, phosphatidic acid formation, myosin light chain phosphorylation and contraction in iris sphincter of the mammalian eye: interaction with the cyclic AMP system.
Topics: Animals; Atropine; Calcium; Carbachol; Cats; Cattle; Cyclic AMP; Dose-Response Relationship, Drug; I | 1988 |
Activation of beta-adrenergic receptors causes stimulation of cyclic AMP, inhibition of inositol trisphosphate, and relaxation of bovine iris sphincter smooth muscle. Biochemical and functional interactions between the cyclic AMP and calcium signalling sy
Topics: Animals; Calcium; Cattle; Cyclic AMP; Dose-Response Relationship, Drug; Inositol 1,4,5-Trisphosphate | 1989 |
The different contributions of prostaglandins (E1, E2, F2 alpha, D2) to the tone and neurogenic response of bovine iris sphincter muscle.
Topics: Animals; Carbachol; Cattle; Electric Stimulation; In Vitro Techniques; Indomethacin; Iris; Muscle Co | 1989 |
Short-term desensitization of prostaglandin F2 alpha receptors increases cyclic AMP formation and reduces inositol phosphates accumulation and contraction in the bovine iris sphincter.
Topics: Animals; Cattle; Cyclic AMP; Diglycerides; Dinoprost; In Vitro Techniques; Indomethacin; Inositol Ph | 1989 |
Involvement of threshold level in the contractile responses for some alpha 1-andrenoceptor agonists in the rabbit iris dilators.
Topics: Adrenergic alpha-Agonists; Animals; In Vitro Techniques; Iris; Male; Muscle Contraction; Muscle, Smo | 1989 |
Dual effects of dynorphin-(1-13) on cholinergic and substance P-ergic transmissions in the rabbit iris sphincter muscle.
Topics: Acetylcholine; Animals; Carbachol; Dynorphins; Electric Stimulation; Endorphins; Female; In Vitro Te | 1985 |
Some characterization of the responses to substance P and other tachykinins in rabbit iris sphincter muscle.
Topics: Animals; Atropine; Carbachol; Eledoisin; In Vitro Techniques; Iris; Kinins; Muscle Contraction; Musc | 1985 |
Different muscarine receptors mediate the prejunctional inhibition of [3H]-noradrenaline release in rat or guinea-pig iris and the contraction of the rabbit iris sphincter muscle.
Topics: Animals; Electric Stimulation; In Vitro Techniques; Iris; Kinetics; Methacholine Compounds; Muscle C | 1989 |
Contractile effect of endothelin on isolated iris sphincter muscle of the pig.
Topics: Animals; Atropine; Capsaicin; Endothelins; In Vitro Techniques; Iris; Muscle Contraction; Muscle, Sm | 1989 |
M2 muscarinic receptors on the iris sphincter muscle differ from those on iris noradrenergic nerves.
Topics: Animals; Drug Interactions; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Iris; Ma | 1989 |
Decrease in neuronal uptake of noradrenaline simply explains the supersensitivity after sympathectomy in the rat iris dilator.
Topics: Acetylcholine; Animals; Catecholamines; Denervation; In Vitro Techniques; Iris; Male; Muscle Contrac | 1989 |
[Role of prostaglandins in the cooling-induced constriction of the iris sphincter].
Topics: Animals; Cattle; Cold Temperature; In Vitro Techniques; Iris; Muscle Contraction; Muscle Tonus; Musc | 1989 |
Radioligand binding studies of postsynaptic alpha 1-adrenoceptors in the rabbit iris dilators.
Topics: Animals; Aorta, Thoracic; Binding, Competitive; In Vitro Techniques; Iris; Kinetics; Male; Muscle Co | 1987 |
Muscarinic and nicotinic synaptic activation of the developing chicken iris.
Topics: Animals; Bungarotoxins; Chick Embryo; Chickens; Iris; Light; Muscle Contraction; Muscles; Neuromuscu | 1987 |
Double reciprocal innervations in dog iris sphincter and dilator muscles.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Biomechanical Phenomena; Dogs; E | 1986 |
Characterization of postsynaptic alpha 1-adrenoceptors in the rabbit iris dilator smooth muscle.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta; Guinea Pigs; In Vitro Techn | 1986 |
A difference in mode of antagonism between optical isomers of a potent selective alpha 1-adrenoceptor blocker (YM-12617) and norepinephrine in isolated rabbit iris dilator and aorta.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Dose-Response Relationship, Drug; In Vitro Techniques; | 1986 |
Evidence for multiple tachykinin receptor subtypes on the rabbit iris sphincter muscle.
Topics: Animals; Iris; Muscle Contraction; Muscle, Smooth; Neurotransmitter Agents; Rabbits; Receptors, Neur | 1988 |
Alpha-adrenoceptor activation of nictitating membrane and iris in cats.
Topics: Adrenergic alpha-Antagonists; Animals; Cats; Dose-Response Relationship, Drug; Epinephrine; Female; | 1988 |
Surgical sympathetic denervation increases alpha 1-adrenoceptor-mediated accumulation of myo-inositol trisphosphate and muscle contraction in rabbit iris dilator smooth muscle.
Topics: Adenosine Triphosphatases; Animals; Arachidonic Acid; Arachidonic Acids; Female; Inositol; Inositol | 1986 |
Adenosine-modulation of cholinergic and non-adrenergic non-cholinergic neurotransmission in the rabbit iris sphincter.
Topics: Adenosine; Animals; Atropine; Autonomic Nervous System; Capsaicin; Electric Stimulation; Female; Iri | 1986 |
Correlative studies on the effect of carbachol on myo-inositol trisphosphate accumulation, myosin light chain phosphorylation and contraction in sphincter smooth muscle of rabbit iris.
Topics: Animals; Atropine; Calcium; Carbachol; Ethers; Female; Inositol 1,4,5-Trisphosphate; Inositol Phosph | 1986 |
Alpha 1-adrenergic receptor induced subsensitivity and supersensitivity in rabbit iris-ciliary body. Effects on myo-inositol trisphosphate accumulation, arachidonate release, and prostaglandin synthesis.
Topics: Animals; Aqueous Humor; Arachidonic Acid; Arachidonic Acids; Ciliary Body; Dexamethasone; Dinoprosto | 1987 |
Effects of indomethacin and prostaglandins on the dog iris sphincter and dilator muscles.
Topics: Animals; Atropine; Dogs; Egtazic Acid; Female; Indomethacin; Iris; Male; Membrane Potentials; Muscle | 1988 |
Desensitization of the isolated bovine iris sphincter muscles by pilocarpine.
Topics: Acetylcholine; Animals; Carbachol; Cattle; Drug Interactions; Drug Tolerance; In Vitro Techniques; I | 1988 |
Functional innervation and contractile properties of the human iris sphincter muscle.
Topics: Aged; Atropine; Child, Preschool; Cholinergic Fibers; Electric Stimulation; Female; Humans; In Vitro | 1988 |
Parasympathetic denervation abolishes acetylcholine-induced relaxation in the rat iris dilator.
Topics: Acetylcholine; Animals; Dilatation; Iris; Muscle Contraction; Muscle Relaxation; Oculomotor Muscles; | 1988 |
Possible mechanisms related to contraction of the bovine iris sphincter in the presence of acetylcholine and carbachol.
Topics: Acetylcholine; Animals; Carbachol; Cattle; Dose-Response Relationship, Drug; Indomethacin; Iris; Mus | 1988 |
Effects of neuropeptide Y on the isolated rabbit iris dilator muscle.
Topics: Animals; Electrophysiology; In Vitro Techniques; Iris; Muscle Contraction; Muscles; Neuropeptide Y; | 1988 |
Different time courses of bovine iris sphincter and dilator muscles after stimulation.
Topics: Animals; Cattle; Electric Stimulation; Electromyography; In Vitro Techniques; Indomethacin; Iris; Mu | 1987 |
Muscle tone and drug sensitivity of isolated bovine iris sphincter are enhanced at low temperatures.
Topics: Animals; Carbachol; Cattle; Dinoprostone; Indomethacin; Iris; Muscle Contraction; Muscle Tonus; Pros | 1987 |
M2 muscarinic receptor subtype is associated with inositol trisphosphate accumulation, myosin light chain phosphorylation and contraction in sphincter smooth muscle of rabbit iris.
Topics: Animals; Atropine; Carbachol; Female; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Ph | 1987 |
Parasympathetic denervation supersensitivity in the rat iris sphincter muscle: an in vitro study.
Topics: Acetylcholine; Animals; Bethanechol Compounds; Cholinesterases; In Vitro Techniques; Iris; Male; Mus | 1987 |
Phorbol ester-induced protein phosphorylation and contraction in sphincter smooth muscle of rabbit iris.
Topics: Animals; Eye Proteins; In Vitro Techniques; Iris; Muscle Contraction; Muscle Proteins; Muscle, Smoot | 1987 |
Modulation by vanadate of the adrenergic characteristics of the iris, ileum, and vas deferens.
Topics: Animals; Epinephrine; Guinea Pigs; Ileum; In Vitro Techniques; Iris; Male; Muscle Contraction; Muscl | 1986 |
[Generation of spontaneous activity in the iris sphincter muscles].
Topics: Animals; Cattle; In Vitro Techniques; Iris; Muscle Contraction; Rabbits | 1986 |
[The role of aqueous divalent cations on spontaneous synchronization in bovine iris muscles].
Topics: Animals; Aqueous Humor; Barium; Calcium; Cations, Divalent; Cattle; Iris; Magnesium; Muscle Contract | 1986 |
[Divalent chelating agents, calcium blockers and metabolic inhibitors had different effects on the iris sphincter muscles].
Topics: Animals; Barium; Calcium Channel Blockers; Cattle; Chelating Agents; Iodoacetates; Iodoacetic Acid; | 1986 |
Effects of divalent cations on the spontaneous synchronization in mammalian iris sphincter muscle cells.
Topics: Action Potentials; Animals; Atropine; Barium; Calcium; Cattle; Dose-Response Relationship, Drug; Ele | 1986 |
Light-evoked contraction of the photosensitive iris of the frog.
Topics: Animals; Calcimycin; Calcium; Egtazic Acid; Iris; Light; Membrane Potentials; Muscle Contraction; Mu | 1985 |
[Photoactivated contraction of the isolated dilator smooth muscle of the rat iris].
Topics: Animals; Catechols; Dose-Response Relationship, Radiation; In Vitro Techniques; Iris; Light; Masopro | 1985 |
Fine structure of elasmobranch iris muscle and associated nervous structures.
Topics: Animals; Fishes; Iris; Microscopy, Electron; Muscle Contraction; Muscle, Smooth; Nerve Endings; Neur | 1970 |
Myoepithelial nexus. Intercellular membrane fusions in the dilator pupillae muscle.
Topics: Animals; Axons; Cell Membrane; Connective Tissue Cells; Epithelial Cells; Iris; Microscopy, Electron | 1971 |
Changes in the physiology and fine structure of the taenia of the guinea-pig caecum following transplantation into the anterior eye chamber.
Topics: Acetylcholinesterase; Animals; Anterior Chamber; Cecum; Female; Ganglia; Guinea Pigs; Histocytochemi | 1971 |
Hexamethonium potentiation of noradrenaline-induced contractions in the dilatator pupillae of the cat.
Topics: Animals; Cats; Drug Synergism; Electric Stimulation; Hexamethonium Compounds; In Vitro Techniques; I | 1967 |
The inhibitory innervation of the bovine iris sphincter.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cattle; In Vitro Techniques; Iri | 1969 |
Relative potency of cholinomimetic drugs on the bovine iris sphincter strips.
Topics: Acetylcholine; Animals; Butyrates; Carbachol; Cattle; Choline; Dose-Response Relationship, Drug; Iri | 1973 |
Effects of echothiophate on cholinesterases in cat irides.
Topics: Acetylcholinesterase; Animals; Butyrates; Carbachol; Carbon Radioisotopes; Cats; Choline; Cholineste | 1974 |
Proceedings: Quantitative studies on acetylcholine receptors of the isolated iris sphincter muscle.
Topics: Acetylcholine; Animals; Atropine; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Tec | 1974 |
Functional autonomic neuromuscular junctions in tissue culture.
Topics: Animals; Autonomic Nervous System; Colon; Culture Techniques; Electric Stimulation; Ganglia, Autonom | 1974 |
Ultrastructure and contractures of the pigeon iris striated muscle.
Topics: Acetylcholine; Animals; Calcium; Columbidae; Edetic Acid; Electric Conductivity; Iris; Magnesium; Me | 1971 |
In vitro effects of diisopropylfluorophosphate on cholinesterases and contractility of intact cat iris.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Carbon Isotopes; Cats; Cholinesterase Inhibitors; Chol | 1972 |
Fine structure of the iris and associated structures of the skates Raja asterias and R. clavata.
Topics: Animals; Endoplasmic Reticulum; Epithelium; Fishes; Iris; Microscopy, Electron; Muscle Contraction; | 1972 |
An analysis of the forces determining the size of the pupil.
Topics: Constriction; Dilatation; Humans; Intraocular Pressure; Iris; Muscle Contraction; Oculomotor Muscles | 1972 |
[Human iris extract].
Topics: Animals; Chymotrypsin; Humans; Iris; Muscle Contraction; Muscle, Smooth; Rats; Tissue Extracts | 1971 |
[The physiology of the blood vessels of the iris].
Topics: Animals; Arteries; Blood Pressure; Carbon Dioxide; Carbonates; Intraocular Pressure; Iris; Muscle Co | 1971 |
Adrenoceptors and cholinoceptors in the rabbit iris.
Topics: Acetylcholine; Animals; Atropine; Dibenzylchlorethamine; Drug Interactions; Epinephrine; Female; In | 1971 |
Stimulation of the iris muscles of rabbits by solar heat.
Topics: Animals; Atropine; Constriction; Dilatation; Epinephrine; Hot Temperature; In Vitro Techniques; Iris | 1971 |
Pupillary phenomena and mechanical changes in the iris of the living rabbit.
Topics: Animals; Atropine; Elasticity; Iris; Light; Magnetics; Muscle Contraction; Pilocarpine; Pressure; Pu | 1970 |
A study of the cholinergic and ganglionic-stimulant drugs on the isolated bovine iris sphincter.
Topics: Animals; Atropine; Autonomic Agents; Binding Sites; Cattle; Drug Antagonism; Ganglia; Hexamethonium | 1971 |
The effect of the treatment of crude tetanus toxin with ganglioside cerebroside complex on sphincter paralysis in the rabbit's eye.
Topics: Adsorption; Animals; Cerebrosides; Gangliosides; Iris; Light; Muscle Contraction; Parasympatholytics | 1968 |
Adrenergic receptors of the bovine iris sphincter.
Topics: Animals; Cattle; Drug Antagonism; In Vitro Techniques; Iris; Isoproterenol; Muscle Contraction; Phen | 1969 |
The influence of catecholamines (epinephrine and norepinephrine) and thiamine, injected simultaneously, on the iris of Bufo viridis.
Topics: Animals; Anura; Drug Antagonism; Drug Synergism; Epinephrine; Iris; Muscle Contraction; Mydriatics; | 1969 |
Mechanical responses of the pigeon iris muscle fibres.
Topics: Acetylcholine; Animals; Columbidae; Electric Stimulation; Equipment and Supplies; Iris; Membrane Pot | 1969 |
Non-ganglionic effects of nicotine in the pig iris sphincter.
Topics: Acetylcholine; Animals; Atropine; Denervation; Hexamethonium Compounds; Iris; Isoflurophate; Muscle | 1965 |