2-propanol has been researched along with Melanosis in 33 studies
2-Propanol: An isomer of 1-PROPANOL. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
propan-2-ol : A secondary alcohol that is propane in which one of the hydrogens attached to the central carbon is substituted by a hydroxy group.
Melanosis: Disorders of increased melanin pigmentation that develop without preceding inflammatory disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the incidence of iridial pigmentation induced by latanoprost ophthalmic solution in Japanese glaucoma patients by a prospective and observer-masked study." | 9.09 | Iridial pigmentation induced by latanoprost ophthalmic solution in Japanese glaucoma patients. ( Abe, K; Chiba, T; Furuichi, M; Iijima, H; Kashiwagi, K; Kogure, S; Shibuya, T; Tsukahara, S, 2001) |
| "To investigate the incidence of iridial pigmentation induced by latanoprost ophthalmic solution in Japanese glaucoma patients by a prospective and observer-masked study." | 5.09 | Iridial pigmentation induced by latanoprost ophthalmic solution in Japanese glaucoma patients. ( Abe, K; Chiba, T; Furuichi, M; Iijima, H; Kashiwagi, K; Kogure, S; Shibuya, T; Tsukahara, S, 2001) |
| "To examine the histopathologic features of iridectomy specimens from patients undergoing glaucoma surgery and to compare histologic abnormalities in a group of patients with a history of latanoprost therapy with those in a group of patients who had no history of prostaglandin therapy (controls)." | 3.72 | A study of iridectomy histopathologic features of latanoprost- and non-latanoprost-treated patients. ( Albert, DM; Damico, CM; Fisher, MR; Gangnon, RE; Gleiser, J; Green, WR; Grossniklaus, HE; Zimbric, ML, 2004) |
| "Naevi or freckles on iris, conjunctiva, or eye lids were not affected." | 2.68 | The incidence and time-course of latanoprost-induced iridial pigmentation as a function of eye color. ( Olsson, K; Stjernschantz, J; Wistrand, PJ, 1997) |
| "Most freckles were observed in the inferior temporal quadrant." | 1.46 | Iris Freckles a Potential Biomarker for Chronic Sun Damage. ( Hofmann-Wellenhof, R; Langmann, G; Mayer, C; Richtig, E; Richtig, G; Richtig, M; Riedl, R; Schwab, C; Tarmann, L; Wackernagel, W; Wedrich, A; Zalaudek, I, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (48.48) | 18.7374 |
| 1990's | 3 (9.09) | 18.2507 |
| 2000's | 8 (24.24) | 29.6817 |
| 2010's | 2 (6.06) | 24.3611 |
| 2020's | 4 (12.12) | 2.80 |
| Authors | Studies |
|---|---|
| Ozturk Durmaz, E | 1 |
| Ridge, A | 1 |
| Lim, BCW | 1 |
| Avalos, G | 1 |
| Laing, M | 1 |
| Featherstone, HJ | 1 |
| Scurrell, EJ | 1 |
| Rhodes, M | 1 |
| Pinheiro de Lacerda, R | 1 |
| Mozo Cuadrado, M | 1 |
| Tabuenca Del Barrio, L | 1 |
| Schwab, C | 1 |
| Mayer, C | 1 |
| Zalaudek, I | 1 |
| Riedl, R | 1 |
| Richtig, M | 1 |
| Wackernagel, W | 1 |
| Hofmann-Wellenhof, R | 1 |
| Richtig, G | 1 |
| Langmann, G | 1 |
| Tarmann, L | 1 |
| Wedrich, A | 1 |
| Richtig, E | 1 |
| Elyadari, M | 1 |
| Zarrouki, M | 1 |
| Elorch, H | 1 |
| Elharchali, S | 1 |
| Elmerrouni, S | 1 |
| Azennoud, S | 1 |
| Hajji, Z | 1 |
| Abdallah, E | 1 |
| Boulanoir, A | 1 |
| Berraho, A | 1 |
| Shields, JA | 1 |
| Shields, CL | 1 |
| Davidson, R | 1 |
| Eagle, RC | 1 |
| Bivolaru, I | 1 |
| Selaru, D | 1 |
| Serghiescu, I | 1 |
| VRABEC, J | 1 |
| STAFFORD, WR | 1 |
| ROE, FJ | 2 |
| MILLICAN, D | 1 |
| MALLETT, JM | 1 |
| JUNCEDA, J | 1 |
| Arranz-Marquez, E | 1 |
| Teus, MA | 1 |
| Saornil, MA | 1 |
| Mendez, MC | 1 |
| Gil, R | 1 |
| Albert, DM | 2 |
| Gangnon, RE | 2 |
| Zimbric, ML | 1 |
| Damico, CM | 1 |
| Fisher, MR | 1 |
| Gleiser, J | 1 |
| Grossniklaus, HE | 2 |
| Green, WR | 2 |
| Darjatmoko, S | 1 |
| Kulkarni, AD | 1 |
| Rennie, IG | 1 |
| Bleehen, SS | 1 |
| Ragge, NK | 1 |
| Acheson, J | 1 |
| Murphree, AL | 1 |
| Selén, G | 1 |
| Stjernschantz, J | 2 |
| Resul, B | 1 |
| Wistrand, PJ | 1 |
| Olsson, K | 1 |
| Taylor, GN | 1 |
| Lloyd, RD | 1 |
| Miller, SC | 1 |
| Muggenburg, BA | 1 |
| Chiba, T | 1 |
| Kashiwagi, K | 1 |
| Kogure, S | 1 |
| Abe, K | 1 |
| Shibuya, T | 1 |
| Furuichi, M | 1 |
| Iijima, H | 1 |
| Tsukahara, S | 1 |
| Tsai, JC | 1 |
| Sivak-Callcott, JA | 1 |
| Haik, BG | 1 |
| Zhang, J | 1 |
| McLean, IW | 1 |
| Tinning, S | 1 |
| Mevorah, B | 1 |
| Frenk, E | 1 |
| Delacrétaz, J | 1 |
| Weingeist, TA | 1 |
| Kupfer, C | 1 |
| Kuwabara, T | 1 |
| Kaiser-Kupfer, M | 1 |
| Babel, J | 1 |
| Schmack, W | 1 |
| Vogel, MH | 1 |
| Dähler, H | 1 |
| Scherz, W | 1 |
| Henkind, P | 1 |
| Friedman, AH | 1 |
| Kendrey, G | 1 |
| Stucchi, CA | 1 |
| Kessous-Odermatt, FL | 1 |
| Paul, EV | 1 |
| Zimmerman, LE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of Latanoprost, Bimatoprost and Travoprost on Periocular Skin Pigmentation[NCT00705757] | Phase 4 | 89 participants (Actual) | Interventional | 2008-03-31 | Completed | ||
| Pigment Dispersion Syndrome With and Without Glaucoma[NCT00001152] | 175 participants | Observational | 1976-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Periocular skin color was measured with the Minolta Chroma Meter CR-400 and the L*a*b* system, also known as Commission Internationale de l'Eclairage. This is a well-accepted unit of measurement in which L* corresponds to brightness and a* and b* correspond to chromaticity.~Measurements were taken at baseline and 1 year. Data from each time point and each location (upper and lower eyelids or cheeks/face) were averaged, and subtracted from the baseline value for that location. Six predetermined areas on and around the upper and lower eyelid and 2 areas of the face/cheek were measured.Upper and lower eyelid values were averaged and reported as single value for each location ie;-upper eyelids, lower eyelid and cheek/face. A decrease in luminance indicates increased pigmentation at the site of measurement." (NCT00705757)
Timeframe: one year
| Intervention | L*a*b* (Mean) | ||
|---|---|---|---|
| Upper Lid | Lower Lid | Cheek/Face | |
| Lumigan | -0.90 | -0.37 | 0.30 |
| Travatan | -0.90 | 0.17 | 0.51 |
| Xalatan | -1.42 | 0.48 | 0.55 |
2 trials available for 2-propanol and Melanosis
| Article | Year |
|---|---|
The incidence and time-course of latanoprost-induced iridial pigmentation as a function of eye color.
Topics: Adrenergic beta-Antagonists; Double-Blind Method; Europe; Eye Color; Glaucoma; Humans; Incidence; In | 1997 |
Iridial pigmentation induced by latanoprost ophthalmic solution in Japanese glaucoma patients.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Eye Color; Female; Glaucoma; Humans; Incide | 2001 |
31 other studies available for 2-propanol and Melanosis
| Article | Year |
|---|---|
Chalk-white fluorescence under Wood light in a case of terra firma-forme dermatosis.
Topics: 2-Propanol; Calcium Carbonate; Dermoscopy; Diagnosis, Differential; Fluorescence; Humans; Hyperpigme | 2021 |
The iris clue: blue-grey periphery, blue collarette and absence of freckles predict risk of skin cancer in a Northern European population.
Topics: Humans; Iris; Melanosis; Skin Neoplasms; White People | 2022 |
Iris biopsy to investigate feline iris hyperpigmentation.
Topics: Animals; Biopsy; Cat Diseases; Cats; Female; Hyperpigmentation; Iris; Iris Neoplasms; Male; Melanoma | 2020 |
Iris mammillations: Images and OCT findings.
Topics: Amblyopia; Female; Humans; Iris; Iris Diseases; Melanosis; Pigmentation Disorders; Scleral Diseases; | 2020 |
Iris Freckles a Potential Biomarker for Chronic Sun Damage.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Biomarkers; Child; Child, Preschool; Chronic Dise | 2017 |
[Ocular melanocytosis].
Topics: Eye Diseases; Humans; Iris; Male; Melanosis; Morocco; Sclera; Young Adult | 2018 |
Iris melanoma arising from sector congenital ocular melanocytosis in a child.
Topics: Adolescent; Eye Diseases; Humans; Iris; Iris Neoplasms; Male; Melanocytes; Melanoma; Melanosis; Micr | 2009 |
[Congenital ocular melanocytosis and delayed psycho-intellectual development--a new association?].
Topics: Child; Developmental Disabilities; Diagnosis, Differential; Eye Diseases; Humans; Iris; Male; Melano | 2009 |
[Bilateral isolated melanosis of the iris].
Topics: Humans; Iris; Iris Diseases; Melanosis | 1959 |
Congenital melanosis oculi. Report of a case.
Topics: Eye Abnormalities; Humans; Iris; Melanosis; Sclera | 1962 |
INDUCTION OF MELANOTIC LESIONS OF THE IRIS IN RATS BY URETHANE GIVEN DURING THE NEONATAL PERIOD.
Topics: Animals; Animals, Newborn; Eye Neoplasms; Iris; Melanoma; Melanosis; Rats; Research; Toxicology; Ure | 1963 |
NEVUS OF OTA.
Topics: Child; Congenital Abnormalities; Conjunctiva; Eye Diseases; Humans; Iris; Melanosis; Nevus; Nevus of | 1965 |
Analysis of irises with a latanoprost-induced change in iris color.
Topics: Aged; Antihypertensive Agents; Biopsy; Exfoliation Syndrome; Eye Color; Female; Glaucoma, Open-Angle | 2004 |
A study of iridectomy histopathologic features of latanoprost- and non-latanoprost-treated patients.
Topics: Antihypertensive Agents; Eye Color; Female; Glaucoma; Humans; Intraocular Pressure; Iridectomy; Iris | 2004 |
A study of histopathological features of latanoprost-treated irides with or without darkening compared with non-latanoprost-treated irides.
Topics: Antihypertensive Agents; Endothelium, Vascular; Fibroblasts; Glaucoma; Humans; Iridectomy; Iris; Iri | 2008 |
Melanosis oculi. An ultrastructural study of an affected iris.
Topics: Aged; Eye Diseases; Female; Humans; Iris; Iris Diseases; Melanocytes; Melanosis | 1983 |
Iris mammillations: significance and associations.
Topics: Adult; Child; Child, Preschool; Female; Humans; Iris; Iris Diseases; Iris Neoplasms; Male; Melanosis | 1996 |
Prostaglandin-induced iridial pigmentation in primates.
Topics: Administration, Topical; Animals; Dinoprost; Dinoprostone; Eye Color; Iris; Iris Diseases; Latanopro | 1997 |
Radium-induced eye melanomas in dogs.
Topics: Animals; Ciliary Body; Dogs; Dose-Response Relationship, Drug; Eye Neoplasms; Hyperplasia; Injection | 2000 |
Latanoprost-induced iris heterochromia and open-angle glaucoma: a clinicopathologic report.
Topics: Antihypertensive Agents; Diagnosis, Differential; Female; Glaucoma, Open-Angle; Humans; Intraocular | 2001 |
Malignant melanoma of the conjunctiva and the iris in a case of primary acquired melanosis of the conjunctiva.
Topics: Aged; Conjunctiva; Eye Diseases; Eye Neoplasms; Eyelid Neoplasms; Female; Humans; Iris; Melanoma; Me | 1978 |
Dermal melanocytosis. Report of an unusual case.
Topics: Adult; Diagnosis, Differential; Female; Humans; Iris; Melanocytes; Melanosis; Nevus; Skin Diseases; | 1977 |
The pigmentary dispersion syndrome and glaucoma.
Topics: Adult; Age Factors; Aged; Atrophy; Corneal Diseases; Epithelium; Eye Diseases; Female; Glaucoma; Hum | 1976 |
The histopathology of pigmentary dispersion syndrome with glaucoma.
Topics: Atrophy; Cornea; Epithelial Cells; Epithelium; Female; Glaucoma; Humans; Iris; Melanosis; Middle Age | 1975 |
[Tumors of the iris].
Topics: Adult; Choroid Neoplasms; Ciliary Body; Eye Neoplasms; Glaucoma; Hemangioma; Humans; Intraocular Pre | 1968 |
[Unilateral melanosis of the iris and ciliary body with glaucoma].
Topics: Adult; Ciliary Body; Diagnosis, Differential; Eye Neoplasms; Female; Glaucoma; Humans; Iris; Melanos | 1972 |
[Clinical aspects of malignant melanoma of the iris (author's transl)].
Topics: Adult; Cysts; Diagnosis, Differential; Eye Diseases; Eye Neoplasms; Female; Fibroma; Granuloma; Hema | 1974 |
External ocular pigmentation.
Topics: Adult; Aged; Conjunctiva; Epinephrine; Eye Diseases; Eye Neoplasms; Eyelid Neoplasms; Facial Neoplas | 1971 |
Melanotic lesions of the eye in August hooded rats induced by urethan or N-hydroxyurethan given during the neonatal period: a histopathological study.
Topics: Animals; Carcinogens; Choroid Neoplasms; Ciliary Body; Eye Diseases; Eye Neoplasms; Female; Injectio | 1969 |
[Benign congenital ocular melanosis].
Topics: Adolescent; Adult; Child; Conjunctiva; Eye Diseases; Female; Humans; Iris; Male; Melanosis; Middle A | 1970 |
Some observations on the ocular pathology of onchocerciasis.
Topics: Adult; Africa; Anterior Chamber; Blindness; Central America; Choroiditis; Congo; Conjunctivitis; Cor | 1970 |