Page last updated: 2024-10-29

2-propanol and Macular Degeneration

2-propanol has been researched along with Macular Degeneration in 41 studies

2-Propanol: An isomer of 1-PROPANOL. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
propan-2-ol : A secondary alcohol that is propane in which one of the hydrogens attached to the central carbon is substituted by a hydroxy group.

Macular Degeneration: Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms.

Research Excerpts

ExcerptRelevanceReference
"Presbyopia is an early manifestation of physiological ageing resulting in the impossibility to read without additional spectacle correction."5.32[Geriatric eye diseases]. ( De Laey, JJ; Tassignon, MJ, 2004)
"Removal of submacular choroidal neovascularization (CNV) in age-related macular degeneration (ARMD) is usually associated with RPE damage and poor visual prognosis."2.69Iris pigment epithelial cell translocation in exudative age-related macular degeneration. A pilot study in patients. ( Foerster, AM; Kirchhof, B; Kube, T; Lappas, A; Rezai, KA; Weinberger, AW, 2000)
"Age-related macular degeneration is one of the most serious diseases in elderly people because of its disasterous visual outcome and its prevalence."2.39[Retinal pigment epithelial cell transplantation: perspective]. ( Tamai, M, 1996)
"No macular edema or recurrent choroidal neovascularization was apparent at any time during the follow-up."1.33Iris pigment epithelial translocation in the treatment of exudative macular degeneration: a 3-year follow-up. ( Aisenbrey, S; Bartz-Schmidt, KU; Esser, P; Hilgers, RD; Lafaut, BA; Szurman, P; Thumann, G; Walter, P, 2006)
"Presbyopia is an early manifestation of physiological ageing resulting in the impossibility to read without additional spectacle correction."1.32[Geriatric eye diseases]. ( De Laey, JJ; Tassignon, MJ, 2004)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199011 (26.83)18.7374
1990's10 (24.39)18.2507
2000's16 (39.02)29.6817
2010's3 (7.32)24.3611
2020's1 (2.44)2.80

Authors

AuthorsStudies
Flores-Márquez, A1
Moreno-Gutiérrez, JÁ1
Chinchurreta-Capote, A1
García-Martín, F1
Rocha-de-Lossada, C1
McGowan, A1
Silvestri, G1
Moore, E1
Silvestri, V1
Patterson, CC1
Maxwell, AP1
McKay, GJ1
Sheridan, CM1
Mason, S1
Pattwell, DM1
Kent, D1
Grierson, I1
Williams, R1
Johnen, S1
Izsvák, Z1
Stöcker, M1
Harmening, N1
Salz, AK1
Walter, P2
Thumann, G3
Semkova, I1
Kreppel, F1
Welsandt, G1
Luther, T1
Kozlowski, J1
Janicki, H1
Kochanek, S1
Schraermeyer, U2
Nicolas, CM1
Robman, LD1
Tikellis, G1
Dimitrov, PN1
Dowrick, A1
Guymer, RH1
McCarty, CA1
Farjo, AA1
Rhee, DJ1
Soong, HK1
Meyer, RF1
Sugar, A1
Zhu, Y1
Liu, ZL1
De Laey, JJ1
Tassignon, MJ1
Kirchhof, B3
Lappas, A2
Foerster, AM2
Weinberger, AW2
Coburger, S1
Schrage, NF1
Kokkinou, D1
Kasper, HU1
Bartz-Schmidt, KU2
Kijlstra, A1
La Heij, E1
Hendrikse, F1
Ayyagari, R1
Mandal, MN1
Karoukis, AJ1
Chen, L1
McLaren, NC1
Lichter, M1
Wong, DT1
Hitchcock, PF1
Caruso, RC1
Moroi, SE1
Maumenee, IH1
Sieving, PA1
Aisenbrey, S1
Lafaut, BA1
Szurman, P1
Hilgers, RD1
Esser, P1
Cai, H1
Shin, MC1
Tezel, TH1
Kaplan, HJ1
Del Priore, LV1
Mensher, JH1
Francois, J1
Bloom, LH1
Brucker, AJ1
Kraff, MC1
Sanders, DR1
Peyman, GA1
Lieberman, HL1
Tarabishy, S1
Sandberg, MA1
Gaudio, AR1
Miller, S1
Weiner, A1
Tamai, M3
Holzwig, DH1
Alexandrakis, G1
Chaudhry, NA1
Liggett, PE1
Weitzman, M1
Geyer, O1
Neudorfer, M1
Rothkoff, L1
Michaeli-Cohen, A1
Lazar, M1
Williams, KA1
Rakoczy, PE1
Sarks, SH1
Daw, N1
Constable, IJ1
Abe, T2
Yoshida, M2
Tomita, H2
Kano, T2
Nakagawa, Y1
Sato, M2
Wada, Y2
Fuse, N2
Yamada, T2
Kube, T1
Rezai, KA1
Steinhorst, UH1
Amdreae, A1
Sistani, F1
Waldmann, KH1
Kastern, T1
Schlaegel, TF1
Neetens, A1
Rubbens, MC1
Burvenich, H1
Ziobrowski, S1
Rich, W1
Whitwell, J1
Gragoudas, ES1
Chandra, SR1
Friedman, E1
Klein, ML1
Van Buskirk, M1
Liles, MR1
Newsome, DA1
Oliver, PD1
Naeser, K1
Nielsen, NE1
Hansen, TE1
Jardine, P1
Sandford-Smith, JH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Generation of Induced Pluripotent Stem (iPS) Cell Lines From Somatic Cells of Participants With Eye Diseases and From Somatic Cells of Matched Controls[NCT01432847]930 participants (Anticipated)Observational2011-09-07Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for 2-propanol and Macular Degeneration

ArticleYear
Immunological factors in the pathogenesis and treatment of age-related macular degeneration.
    Ocular immunology and inflammation, 2005, Volume: 13, Issue:1

    Topics: Anti-Inflammatory Agents; Autoimmunity; Choroid; Humans; Immune System; Immunotherapy; Iris; Macular

2005
[Retinal pigment epithelial cell transplantation: perspective].
    Nippon Ganka Gakkai zasshi, 1996, Volume: 100, Issue:12

    Topics: Animals; Cattle; Cell Death; Cells, Cultured; Humans; Iris; Macaca; Macular Degeneration; Pigment Ep

1996
Differential diagnosis.
    International ophthalmology clinics, 1977,Fall, Volume: 17, Issue:3

    Topics: Amyloidosis; Atrophy; Choroid; Diagnosis, Differential; Eye Neoplasms; Granuloma; Humans; Iris; Irit

1977

Trials

4 trials available for 2-propanol and Macular Degeneration

ArticleYear
Translocation of iris pigment epithelium in patients with exudative age-related macular degeneration: long-term results.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2004, Volume: 242, Issue:8

    Topics: Aged; Female; Fluorescein Angiography; Follow-Up Studies; Fovea Centralis; Humans; Iris; Longitudina

2004
Slit-lamp fluorophotometry in intraocular lens patients.
    Ophthalmology, 1980, Volume: 87, Issue:9

    Topics: Aqueous Humor; Biological Transport; Blood; Capillary Permeability; Edema; Fluoresceins; Fluorometry

1980
Functional analysis after auto iris pigment epithelial cell transplantation in patients with age-related macular degeneration.
    The Tohoku journal of experimental medicine, 1999, Volume: 189, Issue:4

    Topics: Aged; Aged, 80 and over; Cell Transplantation; Cells, Cultured; Female; Humans; Iris; Macular Degene

1999
Iris pigment epithelial cell translocation in exudative age-related macular degeneration. A pilot study in patients.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2000, Volume: 238, Issue:8

    Topics: Aged; Aged, 80 and over; Cell Transplantation; Choroidal Neovascularization; Exudates and Transudate

2000

Other Studies

34 other studies available for 2-propanol and Macular Degeneration

ArticleYear
Laser-induced maculopathy after iris depigmentation cosmetic treatment.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2023, Volume: 58, Issue:1

    Topics: Humans; Hypopigmentation; Iris; Iris Diseases; Lasers; Macular Degeneration; Retinal Diseases

2023
Retinal vascular caliber, iris color, and age-related macular degeneration in the Irish Nun Eye Study.
    Investigative ophthalmology & visual science, 2014, Dec-18, Volume: 56, Issue:1

    Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Eye Color; Female; Follow-Up Studies; Humans; Irel

2014
Transposon-Based, Targeted Ex Vivo Gene Therapy to Treat Age-Related Macular Degeneration (TargetAMD).
    Human gene therapy. Clinical development, 2015, Volume: 26, Issue:2

    Topics: Animals; Cattle; Cell Line; DNA Transposable Elements; Eye Proteins; Genetic Therapy; Humans; Iris;

2015
Replacement of the RPE monolayer.
    Eye (London, England), 2009, Volume: 23, Issue:10

    Topics: Animals; Cell Transplantation; Humans; Iris; Macular Degeneration; Pigment Epithelium of Eye; Stem C

2009
Sleeping Beauty transposon-mediated transfection of retinal and iris pigment epithelial cells.
    Investigative ophthalmology & visual science, 2012, Jul-18, Volume: 53, Issue:8

    Topics: Animals; Blotting, Western; Cattle; Cells, Cultured; DNA Transposable Elements; Electroporation; Eye

2012
Autologous transplantation of genetically modified iris pigment epithelial cells: a promising concept for the treatment of age-related macular degeneration and other disorders of the eye.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Oct-01, Volume: 99, Issue:20

    Topics: Adenoviridae; Aging; Animals; Cell Transplantation; Cells, Cultured; Eye Diseases; Genetic Vectors;

2002
Iris colour, ethnic origin and progression of age-related macular degeneration.
    Clinical & experimental ophthalmology, 2003, Volume: 31, Issue:6

    Topics: Aged; Aged, 80 and over; Clinical Trials as Topic; Cross-Cultural Comparison; Disease Progression; E

2003
Iris-sutured posterior chamber intraocular lens implantation during penetrating keratoplasty.
    Cornea, 2004, Volume: 23, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Follow-Up Studies; Glaucoma; Graft Rejection; Graft Survival; Humans

2004
[A comparison of the mRNA expression of VEGF and its receptor FLK-1 in rabbit iris pigment epithelium cells and retinal pigment epithelial cells].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2003, Volume: 39, Issue:11

    Topics: Animals; Female; Iris; Macular Degeneration; Male; Pigment Epithelium of Eye; Rabbits; Reverse Trans

2003
[Geriatric eye diseases].
    Revue belge de medecine dentaire, 2004, Volume: 59, Issue:1

    Topics: Aged; Aging; Blindness; Cataract; Cornea; Diabetic Retinopathy; Electroretinography; Evoked Potentia

2004
[Transplantation of iris pigment epithelium].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2004, Volume: 101, Issue:9

    Topics: Aged; Animals; Cell Differentiation; Female; Follow-Up Studies; Fundus Oculi; Humans; Iris; Macular

2004
The pigmentation of human iris influences the uptake and storing of zinc.
    Pigment cell research, 2004, Volume: 17, Issue:5

    Topics: Antioxidants; Biological Transport; Eye Color; Gene Expression Regulation; Humans; Iris; Macular Deg

2004
Late-onset macular degeneration and long anterior lens zonules result from a CTRP5 gene mutation.
    Investigative ophthalmology & visual science, 2005, Volume: 46, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Chromosomes, Human, Pair 11; Collagen; DNA Mutational Analysis; Fema

2005
Iris pigment epithelial translocation in the treatment of exudative macular degeneration: a 3-year follow-up.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2006, Volume: 124, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Cell Transplantation; Choroidal Neovascularization; Exudates and Tra

2006
Use of iris pigment epithelium to replace retinal pigment epithelium in age-related macular degeneration: a gene expression analysis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2006, Volume: 124, Issue:9

    Topics: Aged; Aged, 80 and over; Cells, Cultured; Eye Proteins; Gene Expression; Gene Expression Profiling;

2006
Laser therapy for eye disorders.
    Postgraduate medicine, 1984, Nov-15, Volume: 76, Issue:7

    Topics: Diabetic Retinopathy; Eye Diseases; Glaucoma; Humans; Iris; Laser Therapy; Macular Degeneration; Neo

1984
The significance of genetic research in ophthalmology.
    Birth defects original article series, 1982, Volume: 18, Issue:6

    Topics: Chromosome Deletion; Chromosomes, Human, 6-12 and X; Eye Diseases; Eye Neoplasms; Fabry Disease; Hum

1982
Lasers in ophthalmology.
    The Surgical clinics of North America, 1984, Volume: 64, Issue:5

    Topics: Argon; Diabetic Retinopathy; Eye Diseases; Glaucoma; Glaucoma, Open-Angle; Humans; Iris; Laser Thera

1984
Iris pigmentation and extent of disease in patients with neovascular age-related macular degeneration.
    Investigative ophthalmology & visual science, 1994, Volume: 35, Issue:6

    Topics: Aged; Aged, 80 and over; Choroid; Eye Color; Female; Humans; Iris; Macular Degeneration; Male; Middl

1994
[Holzwig iris retractor and use in narrow pupils].
    Klinische Monatsblatter fur Augenheilkunde, 1998, Volume: 213, Issue:1

    Topics: Amblyopia; Cataract Extraction; Equipment Design; Humans; Iris; Lenses, Intraocular; Macular Degener

1998
Spontaneous suprachoroidal hemorrhage in age-related macular degeneration presenting as angle-closure glaucoma.
    Retina (Philadelphia, Pa.), 1998, Volume: 18, Issue:5

    Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Anticoagulants; Antihypertensive Agents; Atrial Fib

1998
Iris retraction syndrome associated with nonrhegmatogenous retinal detachment.
    Acta ophthalmologica Scandinavica, 1998, Volume: 76, Issue:5

    Topics: Aged; Anterior Eye Segment; Ciliary Body; Exudates and Transudates; Follow-Up Studies; Humans; Iris;

1998
Transplantation of autologous iris pigment epithelial cells as a treatment for age-related macular degeneration?
    Transplantation, 1999, Jul-27, Volume: 68, Issue:2

    Topics: Aging; Animals; Epithelial Cells; Iris; Macular Degeneration; Rabbits

1999
Distribution of cathepsin D in human eyes with or without age-related maculopathy.
    Experimental eye research, 1999, Volume: 69, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cathepsin D; Child; Child, Preschool; Ciliary Body; Eye;

1999
Auto iris pigment epithelial cell transplantation in patients with age-related macular degeneration: short-term results.
    The Tohoku journal of experimental medicine, 2000, Volume: 191, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Automation; Cell Transplantation; Electrophysiology; Epithelial Cell

2000
[Autologous subretinal transplantation of cultivated porcine iris pigment epithelial cells (IPE)].
    Klinische Monatsblatter fur Augenheilkunde, 2001, Volume: 218, Issue:3

    Topics: Animals; Cell Movement; Cells, Cultured; Graft Rejection; Iris; Macular Degeneration; Male; Photorec

2001
Experience with hundred Choyce-Mark VIII pseudophakoi.
    Bulletin de la Societe belge d'ophtalmologie, 1979, Volume: 183

    Topics: Adolescent; Adult; Aged; Anesthesia; Aphakia, Postcataract; Cataract Extraction; Cornea; Evaluation

1979
[Bilateral congenital aniridia (author's transl)].
    Klinika oczna, 1977, Volume: 47, Issue:9

    Topics: Cataract; Child; Female; Humans; Iris; Macular Degeneration; Retinal Degeneration

1977
The elderly aphakic and the use of the iris-clip lens.
    Transactions of the ophthalmological societies of the United Kingdom, 1975, Volume: 95, Issue:1

    Topics: Aged; Cataract Extraction; Humans; Iris; Lenses; Macular Degeneration; Postoperative Care; Prosthese

1975
Inherited eye diseases.
    The Practitioner, 1975, Volume: 214, Issue:1283

    Topics: Adult; Albinism; Blepharoptosis; Cataract; Child; Color Vision Defects; Corneal Dystrophies, Heredit

1975
Disciform degeneration of the macula. II. Pathogenesis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1976, Volume: 94, Issue:5

    Topics: Aged; Aging; Choroid; Female; Follow-Up Studies; Humans; Iris; Macular Degeneration; Male; Middle Ag

1976
Antioxidant enzymes in the aging human retinal pigment epithelium.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1991, Volume: 109, Issue:9

    Topics: Aged; Aged, 80 and over; Aging; Catalase; Humans; Iris; Macular Degeneration; Middle Aged; Pigment E

1991
Morphological changes 2 1/2 years after extracapsular cataract extraction with implantation of a posterior chamber lens. A prospective re-examination.
    Acta ophthalmologica, 1990, Volume: 68, Issue:3

    Topics: Aged; Aged, 80 and over; Anterior Chamber; Cornea; Eye; Female; Follow-Up Studies; Gonioscopy; Human

1990
Federov iris-supported intraocular acrylic lens.
    The British journal of ophthalmology, 1974, Volume: 58, Issue:8

    Topics: Cataract Extraction; Cornea; Edema; Female; Glaucoma; Hemorrhage; Humans; Inflammation; Iris; Lenses

1974