Page last updated: 2024-10-29

2-propanol and Leprosy

2-propanol has been researched along with Leprosy in 15 studies

2-Propanol: An isomer of 1-PROPANOL. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
propan-2-ol : A secondary alcohol that is propane in which one of the hydrogens attached to the central carbon is substituted by a hydroxy group.

Leprosy: A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid.

Research Excerpts

ExcerptRelevanceReference
"From 43 Nepalese leprosy patients skin smear negative, and treated with dapsone (diamino diphenyl sulphone), and without any sign of active leprosy or iritis, specimens from iridectomy during cataract surgery were studied histopathologically."7.68Histopathological findings in the iris of dapsone treated leprosy patients. ( Brandt, F; Pradhan, H; Rai, N; Shi, ZR; Thuladar, L; Zhou, HM, 1990)
"From 43 Nepalese leprosy patients skin smear negative, and treated with dapsone (diamino diphenyl sulphone), and without any sign of active leprosy or iritis, specimens from iridectomy during cataract surgery were studied histopathologically."3.68Histopathological findings in the iris of dapsone treated leprosy patients. ( Brandt, F; Pradhan, H; Rai, N; Shi, ZR; Thuladar, L; Zhou, HM, 1990)
"Leprosy is one of the leading causes of corneal hyposensitivity."1.28Corneal sensitivity and correlations between decreased sensitivity and anterior segment pathology in ocular leprosy. ( Cakiner, T; KaraƧorlu, MA; Saylan, T, 1991)
"Leprosy is endemic in regions where other corneal infections which compromise the epithelial barrier property are prevalent and where leprosy bacilli are found in the environment."1.28Ocular leprosy in nine-banded armadillos following intrastromal inoculation. ( Beuerman, RW; Malaty, R; Pedroza, L, 1990)
"We retrospectively analyzed 255 Hansen's disease patients and found low intraocular pressure (less than 7 mm Hg) in 12% of them."1.28Intraocular pressure and iris denervation in Hansen's disease. ( Courtright, P; Gelber, RH; Hussein, N; Lewallen, S; Ostler, HB, 1990)
"5% rifampin according to two dosage schedules."1.26Corneal penetration of rifampin. ( Feldman, MF; Moses, RA, 1977)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19908 (53.33)18.7374
1990's5 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Mahendradas, P1
Rajendran, J1
Sriram, R1
Morais, LNA1
David, JPF1
Peres Lima, JV1
Demachki, S1
Diniz, DG1
Almeida, EF1
Garg, SP1
Kalra, VK1
Verma, N1
Ffytche, TJ1
Daniel, E1
Ebenezer, GJ1
Job, CK1
Feldman, MF1
Moses, RA1
Ratnakar, KS1
Mohan, M1
Richards, WW2
Brandt, F1
Zhou, HM1
Shi, ZR1
Rai, N1
Thuladar, L1
Pradhan, H1
KaraƧorlu, MA1
Cakiner, T1
Saylan, T1
Malaty, R1
Beuerman, RW1
Pedroza, L1
Lewallen, S1
Hussein, N1
Courtright, P1
Ostler, HB1
Gelber, RH1
Beretti, J1
Cahuzac, G1
Emiru, VP1
Arrington, JM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Modified Tarsorrhaphy vs Gold Weight Implant Technique for Paralytic Lagophthalmos Treatment in Leprosy Patients: a Randomized Clinical Trial[NCT04944498]19 participants (Actual)Interventional2019-05-09Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

15 other studies available for 2-propanol and Leprosy

ArticleYear
Moth-Eaten Appearance of the Iris in Hansen Disease.
    JAMA ophthalmology, 2023, Nov-01, Volume: 141, Issue:11

    Topics: Humans; Iris; Leprosy

2023
Acquired acoria and iris pearls in leprosy: Case report.
    European journal of ophthalmology, 2022, Volume: 32, Issue:6

    Topics: Cataract; Humans; Iris; Leprosy; Male; Middle Aged; Quality of Life; Visual Acuity

2022
Aetiopathogenesis of lepromatous iritis.
    Indian journal of ophthalmology, 1983, Volume: 31 Suppl

    Topics: Humans; Iris; Iritis; Leprosy

1983
Role of iris changes as a cause of blindness in lepromatous leprosy.
    The British journal of ophthalmology, 1981, Volume: 65, Issue:4

    Topics: Aged; Atrophy; Blindness; Cataract; Female; Humans; Iris; Iritis; Leprosy; Male; Middle Aged

1981
Pathology of iris in leprosy.
    The British journal of ophthalmology, 1997, Volume: 81, Issue:6

    Topics: Adult; Aged; Female; Humans; Iridocyclitis; Iris; Leprosy; Male; Middle Aged

1997
Corneal penetration of rifampin.
    American journal of ophthalmology, 1977, Volume: 83, Issue:6

    Topics: Administration, Topical; Animals; Aqueous Humor; Chlorobutanol; Ciliary Body; Cornea; Dimethyl Sulfo

1977
Amyloidosis of the iris.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1976, Volume: 11, Issue:3

    Topics: Adult; Amyloidosis; Humans; Iris; Leprosy; Male

1976
Ocular leprosy.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1975, Volume: 93, Issue:8

    Topics: Aged; Eye Diseases; Humans; Iris; Leprosy; Male; Middle Aged; Sclera

1975
Histopathological findings in the iris of dapsone treated leprosy patients.
    The British journal of ophthalmology, 1990, Volume: 74, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Atrophy; Dapsone; Female; Humans; Iris; Iritis; Leprosy; Male; Middl

1990
Corneal sensitivity and correlations between decreased sensitivity and anterior segment pathology in ocular leprosy.
    The British journal of ophthalmology, 1991, Volume: 75, Issue:2

    Topics: Adult; Blindness; Cornea; Corneal Diseases; Humans; Hypesthesia; Iris; Keratitis; Leprosy; Physical

1991
Ocular leprosy in nine-banded armadillos following intrastromal inoculation.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1990, Volume: 58, Issue:3

    Topics: Animals; Armadillos; Ciliary Body; Conjunctiva; Cornea; Eye Infections, Bacterial; Iris; Leprosy; Mi

1990
Intraocular pressure and iris denervation in Hansen's disease.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1990, Volume: 58, Issue:1

    Topics: Autonomic Nervous System; Case-Control Studies; Homeostasis; Humans; Intraocular Pressure; Iris; Lep

1990
[Lesions of ocular leprosy in New Caledonia].
    Archives d'ophtalmologie et revue generale d'ophtalmologie, 1970, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Aged; Cataract; Child; Child, Preschool; Cornea; Eye Diseases; Eyebrows; Eyelids;

1970
Ocular leprosy in Uganda.
    The British journal of ophthalmology, 1970, Volume: 54, Issue:11

    Topics: Adolescent; Adult; Age Factors; Aged; Blindness; Child; Eye Diseases; Female; Humans; Iris; Keratiti

1970
Unsuspected ocular leprosy.
    American journal of ophthalmology, 1969, Volume: 68, Issue:3

    Topics: Adult; Aged; Alopecia; Conjunctiva; Corneal Opacity; Eye Diseases; Eye Manifestations; Eyebrows; Eye

1969