2-propanol has been researched along with Hypermelanosis in 30 studies
2-Propanol: An isomer of 1-PROPANOL. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
propan-2-ol : A secondary alcohol that is propane in which one of the hydrogens attached to the central carbon is substituted by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Terra-firma-forme dermatosis (TFFD) is a little known hyperpigmented skin disease that is more common than expected." | 1.48 | Features of Terra Firma-Forme Dermatosis. ( Aslan, NÇ; Demirci, K; Güler, Ş; Isiyel, E, 2018) |
| "X-linked ocular albinism (OA1) is the most common form of ocular albinism." | 1.35 | Iris hyperpigmentation in a Chinese family with ocular albinism and the GPR143 mutation. ( Xiao, X; Zhang, Q, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (6.67) | 18.2507 |
| 2000's | 7 (23.33) | 29.6817 |
| 2010's | 16 (53.33) | 24.3611 |
| 2020's | 5 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Cohen, PR | 2 |
| Ozturk Durmaz, E | 1 |
| Aslan, NÇ | 1 |
| Güler, Ş | 1 |
| Demirci, K | 1 |
| Isiyel, E | 1 |
| Mattessich, S | 1 |
| Aubert, P | 1 |
| Rees, A | 1 |
| Winkler, JK | 1 |
| Enk, AH | 1 |
| Haenssle, HA | 1 |
| Toberer, F | 1 |
| van der Velden, S | 1 |
| van Neer, F | 1 |
| Pallure, V | 1 |
| Ameline, M | 1 |
| Plantin, P | 1 |
| Bessis, D | 1 |
| Guarneri, C | 3 |
| Tchernev, G | 1 |
| Chokoeva, AA | 1 |
| Ananiev, J | 1 |
| Wollina, U | 1 |
| Fernández-Crehuet, P | 1 |
| Ruiz-Villaverde, R | 1 |
| Ashique, KT | 1 |
| Kaliyadan, F | 1 |
| Goyal, T | 1 |
| Blattner, CM | 1 |
| Perry, B | 1 |
| Snider, K | 1 |
| Young, J | 1 |
| Greywal, T | 1 |
| Cannavò, SP | 2 |
| Oztürk, F | 1 |
| Kocabaş, E | 1 |
| Ertan, P | 1 |
| Ermertcan, AT | 1 |
| Guarneri, F | 1 |
| Coffey, N | 1 |
| Ali, Z | 1 |
| Grau, J | 1 |
| Lipp, MB | 1 |
| Athalye, L | 1 |
| Nami, N | 1 |
| Featherstone, HJ | 1 |
| Scurrell, EJ | 1 |
| Rhodes, M | 1 |
| Pinheiro de Lacerda, R | 1 |
| Vaidya, S | 1 |
| Yaghy, A | 1 |
| Shields, CL | 1 |
| Hawks, M | 1 |
| Collenborne, C | 1 |
| López-Herrero, F | 1 |
| Rueda-Rueda, T | 1 |
| Sánchez-Vicente, JL | 1 |
| Seva-Silva, N | 1 |
| Xiao, X | 1 |
| Zhang, Q | 1 |
| Swann, PG | 1 |
| Kwong, E | 1 |
| Micheli, T | 1 |
| Cheung, LM | 1 |
| Sharma, S | 1 |
| Assaad, NN | 1 |
| Guzowski, M | 1 |
| Francis, IC | 1 |
| Norman, J | 1 |
| Coroneo, MT | 1 |
| Evereklioglu, C | 1 |
| Inaloz, HS | 1 |
| Kirtak, N | 1 |
| McCarey, BE | 1 |
| Kapik, BM | 1 |
| Kane, FE | 1 |
| Zhan, GL | 1 |
| Toris, CB | 1 |
| Camras, CB | 1 |
| Wang, YL | 1 |
| Bito, LZ | 1 |
| Yukishige, K | 1 |
| Fujimoto, S | 1 |
| Ueyama, H | 1 |
| Fujiwara, S | 1 |
| Kumamoto, T | 1 |
| Tsuda, T | 1 |
| Prota, G | 1 |
| Vincensi, MR | 1 |
| Napolitano, A | 1 |
| Selen, G | 1 |
| Stjernschantz, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of Latanoprost, Bimatoprost and Travoprost on Periocular Skin Pigmentation[NCT00705757] | Phase 4 | 89 participants (Actual) | Interventional | 2008-03-31 | Completed | ||
| Efficacy and Safety of Topical Bimatoprost Solution 0.03% in Stable Vitiligo:A Preliminary Study[NCT01202513] | Phase 4 | 20 participants (Actual) | Interventional | 2010-08-31 | Withdrawn (stopped due to regulatory reasons) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Periocular skin color was measured with the Minolta Chroma Meter CR-400 and the L*a*b* system, also known as Commission Internationale de l'Eclairage. This is a well-accepted unit of measurement in which L* corresponds to brightness and a* and b* correspond to chromaticity.~Measurements were taken at baseline and 1 year. Data from each time point and each location (upper and lower eyelids or cheeks/face) were averaged, and subtracted from the baseline value for that location. Six predetermined areas on and around the upper and lower eyelid and 2 areas of the face/cheek were measured.Upper and lower eyelid values were averaged and reported as single value for each location ie;-upper eyelids, lower eyelid and cheek/face. A decrease in luminance indicates increased pigmentation at the site of measurement." (NCT00705757)
Timeframe: one year
| Intervention | L*a*b* (Mean) | ||
|---|---|---|---|
| Upper Lid | Lower Lid | Cheek/Face | |
| Lumigan | -0.90 | -0.37 | 0.30 |
| Travatan | -0.90 | 0.17 | 0.51 |
| Xalatan | -1.42 | 0.48 | 0.55 |
2 reviews available for 2-propanol and Hypermelanosis
| Article | Year |
|---|---|
Terra firma-forme dermatosis: report of a series of 11 cases and a brief review of the literature.
Topics: 2-Propanol; Adolescent; Adult; Aged; Child; Ethanol; Female; Humans; Hygiene; Hyperpigmentation; Mal | 2016 |
Imipramine-Induced Cutaneous and Iris Hyperpigmentation: A Case Report and Literature Review.
Topics: Antidepressive Agents, Tricyclic; Humans; Hyperpigmentation; Imipramine; Iris; Skin | 2022 |
1 trial available for 2-propanol and Hypermelanosis
| Article | Year |
|---|---|
Low incidence of iris pigmentation and eyelash changes in 2 randomized clinical trials with unoprostone isopropyl 0.15%.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Betaxolol; Dinoprost; Double-Blind Method; | 2004 |
27 other studies available for 2-propanol and Hypermelanosis
| Article | Year |
|---|---|
Terra Firma-Forme Dermatosis: Rubbing with Alcohol Establishes the Diagnosis.
Topics: 2-Propanol; Aged, 80 and over; Humans; Hyperpigmentation; Male; Skin Diseases | 2020 |
Chalk-white fluorescence under Wood light in a case of terra firma-forme dermatosis.
Topics: 2-Propanol; Calcium Carbonate; Dermoscopy; Diagnosis, Differential; Fluorescence; Humans; Hyperpigme | 2021 |
Features of Terra Firma-Forme Dermatosis.
Topics: 2-Propanol; Adolescent; Adult; Child; Child, Preschool; Female; Humans; Hyperpigmentation; Infant; M | 2018 |
Bilateral brown plaques behind the ears.
Topics: 2-Propanol; Aged, 80 and over; Alzheimer Disease; Diagnosis, Differential; Female; Humans; Hyperpigm | 2018 |
Reticular hyperpigmentation on the trunk and flexures of the extremities in a 16-year-old boy.
Topics: 2-Propanol; Acanthosis Nigricans; Adolescent; Dermoscopy; Diagnosis, Differential; Humans; Hyperpigm | 2019 |
[A girl with brown skin abnormalities of the neck].
Topics: 2-Propanol; Child; Diagnosis, Differential; Female; Humans; Hyperpigmentation; Neck; Skin Diseases; | 2013 |
[Terra firma-forme dermatosis].
Topics: 2-Propanol; Acanthosis Nigricans; Adolescent; Ankle; Child; Child, Preschool; Comorbidity; Diagnosis | 2013 |
[10-year-old boy with blackish brown skin alterations].
Topics: 2-Propanol; Child; Chronic Disease; Dermatitis; Diagnosis, Differential; Ethanol; Humans; Hyperpigme | 2014 |
Terra firma-forme dermatosis.
Topics: 2-Propanol; Administration, Cutaneous; Arm; Child; Female; Humans; Hyperpigmentation; Skin | 2016 |
Clinical pearl: increasing utility of isopropyl alcohol for cutaneous dyschromia.
Topics: 2-Propanol; Administration, Cutaneous; Dermatologic Agents; Humans; Hyperpigmentation | 2016 |
Non-invasive methods to establish the diagnosis of terra firma-forme dermatosis: The SMART (Skin Modified by Alcohol Rubbing Test) evaluation and dermoscopy.
Topics: 2-Propanol; Dermoscopy; Humans; Hyperpigmentation; Skin | 2016 |
'Dirty lesions' on the neck and abdomen.
Topics: 2-Propanol; Adolescent; Diagnosis, Differential; Female; Humans; Hyperpigmentation; Skin Diseases | 2017 |
Is this skin diseased, or is it just dirty?
Topics: 2-Propanol; Administration, Topical; Child; Diagnosis, Differential; Humans; Hyperpigmentation; Male | 2009 |
Terra firma-forme dermatosis.
Topics: 2-Propanol; Child; Female; Humans; Hyperpigmentation; Skin; Solvents; Therapeutic Irrigation; Treatm | 2010 |
Terra firma-forme dermatosis.
Topics: 2-Propanol; Child; Diagnosis, Differential; Humans; Hygiene; Hyperpigmentation; Male; Skin; Skin Dis | 2008 |
Bimatoprost-induced iris hyperpigmentation: beauty in the darkened eye of the beholder.
Topics: Administration, Topical; Antihypertensive Agents; Bimatoprost; Eyelashes; Female; Humans; Hyperpigme | 2019 |
Iris biopsy to investigate feline iris hyperpigmentation.
Topics: Animals; Biopsy; Cat Diseases; Cats; Female; Hyperpigmentation; Iris; Iris Neoplasms; Male; Melanoma | 2020 |
Pigmented Iris Lesion on Anterior-Segment Swept-Source Optical Coherence Tomography.
Topics: Cysts; Humans; Hyperpigmentation; Iris; Iris Diseases; Male; Middle Aged; Photography; Pigment Epith | 2021 |
Asymptomatic Hyperpigmented Iris Lesion.
Topics: Asymptomatic Diseases; Child; Female; Humans; Hyperpigmentation; Iris; Melanoma; Uveal Neoplasms | 2018 |
Iris mammillations in a patient with type 1 neurofibromatosis.
Topics: Adolescent; Humans; Hyperpigmentation; Iris; Male; Neurofibromatosis 1 | 2019 |
Iris hyperpigmentation in a Chinese family with ocular albinism and the GPR143 mutation.
Topics: Albinism, Ocular; Asian People; Child; China; Electrophoresis, Agar Gel; Eye Proteins; Family; Femal | 2009 |
The naevus of Ota.
Topics: Conjunctiva; Eye Neoplasms; Face; Facial Neoplasms; Female; Fundus Oculi; Humans; Hyperpigmentation; | 2010 |
Acute haptic-induced pigmentary glaucoma with an AcrySof intraocular lens.
Topics: Acrylic Resins; Atrophy; Device Removal; Glaucoma, Open-Angle; Humans; Hyperpigmentation; Intraocula | 2002 |
Psoriasis with pigment dispersion syndrome: report of two cases.
Topics: Adult; Cornea; Female; Follow-Up Studies; Glaucoma; Humans; Hyperpigmentation; Iris; Male; Psoriasis | 2003 |
Prostaglandin-induced iris color darkening. An experimental model.
Topics: Administration, Topical; Animals; Eye Color; Female; Ganglia, Sympathetic; Ganglionectomy; Hyperpigm | 1998 |
[Two adult siblings with Chédiak-Higashi syndrome presenting as hyperpigmentation of the skin and the iris].
Topics: Adult; Chediak-Higashi Syndrome; Humans; Hyperpigmentation; Iris; Male; Melanosomes; Nuclear Family; | 1999 |
Latanoprost stimulates eumelanogenesis in iridial melanocytes of cynomolgus monkeys.
Topics: Administration, Topical; Animals; Antihypertensive Agents; Female; Hyperpigmentation; Iris; Iris Dis | 2000 |