2-propanol has been researched along with Gram-Positive Bacterial Infections in 6 studies
2-Propanol: An isomer of 1-PROPANOL. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
propan-2-ol : A secondary alcohol that is propane in which one of the hydrogens attached to the central carbon is substituted by a hydroxy group.
Gram-Positive Bacterial Infections: Infections caused by bacteria that retain the crystal violet stain (positive) when treated by the gram-staining method.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Post-operative endophthalmitis is a serious complication of intraocular surgery which may present acutely or chronically." | 1.43 | Chronic post-operative iris prosthesis endophthalmitis in a patient with traumatic aniridia: a case report. ( Firl, KC; Montezuma, SR, 2016) |
| "Most bacteria that cause nosocomial infections can retain their viability even after exposure to disinfectants in routine practice." | 1.37 | [Investigation of the efficacy of some disinfectants against nosocomial Staphylococcus aureus and Enterococcus spp. isolates]. ( Akın, A; Arıkan Akan, O; Eryılmaz, M, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tinajero, CG | 1 |
| Bobadilla-Del Valle, M | 1 |
| Alvarez, JA | 1 |
| Mosqueda, JL | 1 |
| Ponce De Leon, A | 1 |
| Macias, AE | 1 |
| Yodoshi, T | 1 |
| Ueda, S | 1 |
| Goldman, RD | 1 |
| Swenson, BR | 1 |
| Hedrick, TL | 1 |
| Metzger, R | 1 |
| Bonatti, H | 1 |
| Pruett, TL | 1 |
| Sawyer, RG | 1 |
| Eryılmaz, M | 1 |
| Akın, A | 1 |
| Arıkan Akan, O | 1 |
| Brayer, C | 1 |
| Micheau, P | 1 |
| Bony, C | 1 |
| Tauzin, L | 1 |
| Pilorget, H | 1 |
| Sampériz, S | 1 |
| Alessandri, JL | 1 |
| Firl, KC | 1 |
| Montezuma, SR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Residual Effect of Chlorhexidine 2% / Isopropyl Alcohol 70% Compared to Triclosan 1% / Isopropyl Alcohol 70%[NCT01762904] | Phase 3 | 135 participants (Actual) | Interventional | 2013-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"135 units of measurement to test two antiseptics and two controls. Principal unit of measurement: four determinations of bacterial counts in a subject for antiseptics and controls to test each of the application sites.~All volunteers was provided with a neutral soap without antiseptics for use of two weeks. 2% chlorhexidine in 70% isopropyl alcohol and 1% triclosan in 70% isopropyl alcohol, Deionized water redistilled and Scrub the skin without prior application of any substance was tested. We prepared four skin's areas of 25 cm2, two in each forearm. The solution remained on the skin for 60s, 3h and 24h.~Presence of allergy or any skin reaction at 24 hours after the antiseptic application." (NCT01762904)
Timeframe: 24 hours
| Intervention | participants (Median) |
|---|---|
| Whole Group of 135 Units of Measurement | 0 |
"135 units of measurement to test two controls. Principal unit of measurement: four determinations of bacterial counts in a subject for antiseptics and controls to test each of the application sites.~All volunteers was provided with a neutral soap without antiseptics for use of two weeks. Deionized water redistilled (Control 2: Control with scrub) and Scrub the skin without prior application of any substance (Control1: Control without scrub) was tested. Were prepared two skin's areas of 25 cm2 randomly selected. The solution remained on the skin for 60s, 3h and 24h.~Cultures was taken with a scrub-cup of 5 cm2 pressed over the skin, added a 3 mL of culture broth. The skin was scrub with a sterile rubber policeman for 1 minute and the procedure conducted once again. Both aliquots came together in a sterile tube, a sample of 50 microliters were spread in a plate containing a neutralizing agar and were incubated at 35°C for 24 h." (NCT01762904)
Timeframe: 24 hrs
| Intervention | (CFU/cm2) (Median) | |||||
|---|---|---|---|---|---|---|
| Control 1: without scrub 0 h | Control 2: scrub with Deionized water redisti 0 h | Control 1: without scrub 3 h | Control 2: scrub with Deionized water redisti 3 h | Control 1: without scrub 24 h | Control 2: scrub with Deionized water redisti 24 h | |
| Whole Group of 135 Units of Measurement | 480 | 216 | 288 | 96 | 288 | 96 |
"135 determinations to evaluate residual effect of 2% chlorhexidine in 70% isopropyl alcohol.~All volunteers was provided with a neutral soap without antiseptics for use of two weeks. 2% chlorhexidine in 70% isopropyl alcohol was tested. Were prepared the skin area of 25 cm2 randomly selected. The solution remained on the skin for 60s, 3h and 24h, everyone on different days.~Cultures was taken with a scrub-cup of 5 cm2 pressed over the skin, added a 3 mL of culture broth. The skin was scrub with a sterile rubber policeman for 1 minute and the procedure conducted once again. Both aliquots came together in a sterile tube, a sample of 50 microliters were spread in a plate containing a neutralizing agar and were incubated at 35°C for 24 h." (NCT01762904)
Timeframe: 24 hours
| Intervention | (CFU/cm2) (Median) | ||
|---|---|---|---|
| 0 h | 3 h | 24 h | |
| Whole Group of 135 Units of Measurement | 24 | 48 | 24 |
"135 determinations to test 1% triclosan in 70% isopropyl alcohol.~All volunteers was provided with a neutral soap without antiseptics for use of two weeks. 1% triclosan in 70% isopropyl alcohol was tested. Were prepared the skin area of 25 cm2 randomly selected. The solution remained on the skin for 60s, 3h and 24h, everyone on different days.~Cultures was taken with a scrub-cup of 5 cm2 pressed over the skin, added a 3 mL of culture broth. The skin was scrub with a sterile rubber policeman for 1 minute and the procedure conducted once again. Both aliquots came together in a sterile tube, a sample of 50 microliters were spread in a plate containing a neutralizing agar and were incubated at 35°C for 24 h." (NCT01762904)
Timeframe: 24 hours
| Intervention | (CFU/cm2) (Median) | ||
|---|---|---|---|
| 0 h | 3 h | 24 h | |
| Whole Group of 135 Units of Measurement | 48 | 48 | 96 |
1 trial available for 2-propanol and Gram-Positive Bacterial Infections
| Article | Year |
|---|---|
Effects of preoperative skin preparation on postoperative wound infection rates: a prospective study of 3 skin preparation protocols.
Topics: 2-Propanol; Adult; Aged; Anti-Infective Agents, Local; Chlorhexidine; Female; Gram-Positive Bacteria | 2009 |
5 other studies available for 2-propanol and Gram-Positive Bacterial Infections
| Article | Year |
|---|---|
Vancomycin-resistant Enterococcus faecium sensitivity to isopropyl alcohol before and after implementing alcohol hand rubbing in a hospital.
Topics: 2-Propanol; Disinfectants; Drug Tolerance; Enterococcus faecium; Gram-Positive Bacterial Infections; | 2019 |
Skin preparation for prevention of peripheral blood culture contamination in children.
Topics: 2-Propanol; Anti-Infective Agents, Local; Antisepsis; Bacteremia; Blood Culture; Child; Child, Presc | 2019 |
[Investigation of the efficacy of some disinfectants against nosocomial Staphylococcus aureus and Enterococcus spp. isolates].
Topics: 2-Propanol; Chlorhexidine; Cross Infection; Disinfectants; Drug Resistance, Bacterial; Enterococcus; | 2011 |
[Neonatal accidental burn by isopropyl alcohol].
Topics: 2-Propanol; Accidents, Home; Bacteremia; Burns, Chemical; Enterococcus faecalis; Fatal Outcome; Gram | 2004 |
Chronic post-operative iris prosthesis endophthalmitis in a patient with traumatic aniridia: a case report.
Topics: Aniridia; Device Removal; Endophthalmitis; Eye Injuries; Gram-Positive Bacterial Infections; Humans; | 2016 |